Details for: ARHGEF16

Gene ID: 27237

Symbol: ARHGEF16

Ensembl ID: ENSG00000130762

Description: Rho guanine nucleotide exchange factor 16

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 29.2931
    Cell Significance Index: -7.4300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 11.0429
    Cell Significance Index: -7.4100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 7.6670
    Cell Significance Index: -7.3200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.2850
    Cell Significance Index: -8.8000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.3362
    Cell Significance Index: 105.8900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.3185
    Cell Significance Index: 66.8000
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 2.2413
    Cell Significance Index: 24.2900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.1812
    Cell Significance Index: 29.7600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.7948
    Cell Significance Index: 93.2400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.4612
    Cell Significance Index: 21.9000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.3326
    Cell Significance Index: 144.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1416
    Cell Significance Index: 185.6800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.9222
    Cell Significance Index: 5.7300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.8127
    Cell Significance Index: 19.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.8098
    Cell Significance Index: 28.4600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.7940
    Cell Significance Index: 22.1900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7751
    Cell Significance Index: 53.6000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6314
    Cell Significance Index: 62.4600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.6175
    Cell Significance Index: 8.7900
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.6143
    Cell Significance Index: 4.0100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5546
    Cell Significance Index: 500.8000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.5151
    Cell Significance Index: 10.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4633
    Cell Significance Index: 29.2000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4607
    Cell Significance Index: 9.9800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4240
    Cell Significance Index: 9.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3957
    Cell Significance Index: 18.4500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3466
    Cell Significance Index: 11.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2809
    Cell Significance Index: 7.6500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2492
    Cell Significance Index: 6.2300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2153
    Cell Significance Index: 26.4800
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.1973
    Cell Significance Index: 2.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1869
    Cell Significance Index: 33.7000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.1662
    Cell Significance Index: 1.7200
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.1375
    Cell Significance Index: 0.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1360
    Cell Significance Index: 26.9800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1089
    Cell Significance Index: 59.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0699
    Cell Significance Index: 13.3100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0629
    Cell Significance Index: 4.6900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0627
    Cell Significance Index: 1.6500
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.0315
    Cell Significance Index: 0.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0175
    Cell Significance Index: 2.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0126
    Cell Significance Index: 5.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0012
    Cell Significance Index: 2.3100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0011
    Cell Significance Index: 0.0500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0004
    Cell Significance Index: -0.3000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0013
    Cell Significance Index: -0.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0029
    Cell Significance Index: -1.8400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0038
    Cell Significance Index: -6.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0049
    Cell Significance Index: -7.6000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0064
    Cell Significance Index: -2.2900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0074
    Cell Significance Index: -10.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0077
    Cell Significance Index: -5.7000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0082
    Cell Significance Index: -0.2200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0105
    Cell Significance Index: -5.9400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0111
    Cell Significance Index: -3.2000
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.0115
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0124
    Cell Significance Index: -7.7300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0130
    Cell Significance Index: -1.5200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0146
    Cell Significance Index: -1.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0164
    Cell Significance Index: -0.8300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0166
    Cell Significance Index: -1.9000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0203
    Cell Significance Index: -9.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0241
    Cell Significance Index: -3.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0300
    Cell Significance Index: -6.0100
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.0319
    Cell Significance Index: -0.1200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0336
    Cell Significance Index: -4.8800
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.0360
    Cell Significance Index: -0.5000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0364
    Cell Significance Index: -1.4900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0367
    Cell Significance Index: -7.7300
  • Cell Name: salivary gland glandular cell (CL1001596)
    Fold Change: -0.0467
    Cell Significance Index: -0.2600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0484
    Cell Significance Index: -6.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0524
    Cell Significance Index: -6.7200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0624
    Cell Significance Index: -1.6000
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.0625
    Cell Significance Index: -0.6500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0710
    Cell Significance Index: -7.4000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0713
    Cell Significance Index: -1.2000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0755
    Cell Significance Index: -0.7000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0804
    Cell Significance Index: -3.7800
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0854
    Cell Significance Index: -0.5300
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0859
    Cell Significance Index: -0.7300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0874
    Cell Significance Index: -6.9200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0887
    Cell Significance Index: -5.4400
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0936
    Cell Significance Index: -0.6800
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1024
    Cell Significance Index: -1.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1032
    Cell Significance Index: -7.3000
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1049
    Cell Significance Index: -1.4700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1133
    Cell Significance Index: -7.6200
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1171
    Cell Significance Index: -0.9000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1181
    Cell Significance Index: -9.0700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1185
    Cell Significance Index: -3.4900
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.1213
    Cell Significance Index: -1.3300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1275
    Cell Significance Index: -1.5200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1378
    Cell Significance Index: -7.1800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1421
    Cell Significance Index: -9.1700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1450
    Cell Significance Index: -8.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1458
    Cell Significance Index: -8.1800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1480
    Cell Significance Index: -2.1200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1509
    Cell Significance Index: -1.2100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.1561
    Cell Significance Index: -2.1900
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1586
    Cell Significance Index: -1.2200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ARHGEF16 is a guanine nucleotide exchange factor (GEF) that specifically activates Rho GTPases, a family of small GTP-binding proteins involved in regulating actin cytoskeleton dynamics, cell migration, and cell proliferation. This GEF activity enables ARHGEF16 to modulate the activity of Rho GTPases, thereby influencing various cellular processes. **Pathways and Functions:** ARHGEF16 is involved in multiple signaling pathways, including: 1. **Activation of gtpase activity**: ARHGEF16 activates Rho GTPases by facilitating the exchange of GDP for GTP, thereby regulating their activity. 2. **Cadherin binding**: ARHGEF16 interacts with cadherins, a family of adhesion molecules, to regulate cell-cell adhesion and migration. 3. **Cdc42 gtpase cycle**: ARHGEF16 modulates the activity of Cdc42, a Rho GTPase involved in cell migration, polarity, and actin cytoskeleton organization. 4. **Cell chemotaxis**: ARHGEF16 regulates chemotaxis, the movement of cells in response to chemical gradients, by modulating Rho GTPase activity. 5. **Cell death signalling via NRAGE**: ARHGEF16 interacts with NRAGE, a receptor that regulates cell death and survival, to modulate signaling pathways involved in apoptosis and necrosis. **Clinical Significance:** Dysregulation of ARHGEF16 has been implicated in various diseases, including: 1. **Cancer**: Overexpression of ARHGEF16 has been observed in various types of cancer, including breast, lung, and colon cancer, highlighting its potential as a therapeutic target. 2. **Neurodegenerative diseases**: ARHGEF16 has been implicated in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, where its dysregulation contributes to neuronal dysfunction and death. 3. **Inflammatory disorders**: ARHGEF16 has been shown to regulate inflammatory responses, and its dysregulation has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, ARHGEF16 is a multifaceted gene that plays a critical role in regulating various cellular processes, including cell signaling, chemotaxis, and death signaling. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into its role in disease pathology and potential therapeutic applications.

Genular Protein ID: 1162622310

Symbol: ARHGG_HUMAN

Name: Rho guanine nucleotide exchange factor 16

UniProtKB Accession Codes:

Q5VV41 Q86TF0 Q99434

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 3 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 4 RefSeq 3 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20679435

Title: Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism.

PubMed ID: 20679435

DOI: 10.1083/jcb.201005141

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21139582

Title: The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42.

PubMed ID: 21139582

DOI: 10.1038/sj.bjc.6606026

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 30245514

Title: Splice-altering variant in COL11A1 as a cause of nonsyndromic hearing loss DFNA37.

PubMed ID: 30245514

DOI: 10.1038/s41436-018-0285-0

Sequence Information:

  • Length: 709
  • Mass: 80105
  • Checksum: 9672AB3C92311BEB
  • Sequence:
    • MAQRHSDSSL EEKLLGHRFH SELRLDAGGN PASGLPMVRG SPRVRDDAAF QPQVPAPPQP 
RPPGHEEPWP IVLSTESPAA LKLGTQQLIP KSLAVASKAK TPARHQSFGA AVLSREAARR 
DPKLLPAPSF SLDDMDVDKD PGGMLRRNLR NQSYRAAMKG LGKPGGQGDA IQLSPKLQAL 
AEEPSQPHTR SPAKNKKTLG RKRGHKGSFK DDPQLYQEIQ ERGLNTSQES DDDILDESSS 
PEGTQKVDAT IVVKSYRPAQ VTWSQLPEVV ELGILDQLST EERKRQEAMF EILTSEFSYQ 
HSLSILVEEF LQSKELRATV TQMEHHHLFS NILDVLGASQ RFFEDLEQRH KAQVLVEDIS 
DILEEHAEKH FHPYIAYCSN EVYQQRTLQK LISSNAAFRE ALREIERRPA CGGLPMLSFL 
ILPMQRVTRL PLLMDTLCLK TQGHSERYKA ASRALKAISK LVRQCNEGAH RMERMEQMYT 
LHTQLDFSKV KSLPLISASR WLLKRGELFL VEETGLFRKI ASRPTCYLFL FNDVLVVTKK 
KSEESYMVQD YAQMNHIQVE KIEPSELPLP GGGNRSSSVP HPFQVTLLRN SEGRQEQLLL 
SSDSASDRAR WIVALTHSER QWQGLSSKGD LPQVEITKAF FAKQADEVTL QQADVVLVLQ 
QEDGWLYGER LRDGETGWFP EDFARFITSR VAVEGNVRRM ERLRVETDV

Genular Protein ID: 3147299801

Symbol: B3KTS4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KTS4

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 3 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 709
  • Mass: 80184
  • Checksum: 2158558725F7DD23
  • Sequence:
    • MAQRHSDSSL EEKLLGHRFH SELRLDAGGN PASGLPMVRG SPRVRDDAAF QPQVPAPPQP 
RPPGHEEPWP IVLSTESPAA LKLGTQQLIP KSLAVASKAK TPARHQSFGA AVLSREAARR 
DPKLLPAPSF SLDDMDVDKD PGGMLRRNLR NQSYRAAMKG LGKPGGQGDA IQLSPKLQAL 
AEEPSQPHTR SPAKNKKTLG RKRGHKGSFK DDPQLYQEIQ ERGLNTSQES DDDILDESSS 
PEGTQKVDAT IVVKSYRPAQ VTWSQLPEVV ELGILDQLST EERKRQEAMF EILTSEFSYQ 
HSLSILVEEF LQSKELRATV TQMEHHHLFS NILDVLGASQ RFFEDLEQRH KAQVLVEDIS 
DILEEHAEKY FHPYIAYCSN EVYQQRTLQK LISSNAAFRE ALREIERRPA CGGLPMLSFL 
ILPMQRVTRL PLLMDTLRLK TQGHSERYKA ASRALKAISK LVRQCNEGAH RMERMEQMYT 
LHTQLDFSKV KSLPLISASR WLLKRGELFL VEETGLFRKI ASRPTCYLFL FNDVLVVTKK 
KSEESYMVQD YAQMNHIQVE KIEPSELPLP GGGNRSSSVP HPFQVTLLRN SEGRQEQLLL 
SSDSASDRAR WIVALTHSER QWQGLSSKGD LPQVEITKAF FAKQADEVTL QQADVVLVLQ 
QEDGWLYGER LRDGETGWFP EDFARFITSR VAVEGNVRRM ERLRVETDV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.