Details for: GRM4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 14.2028
Cell Significance Index: -5.7700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 2.9609
Cell Significance Index: 85.3100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 2.8745
Cell Significance Index: 49.2600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.5200
Cell Significance Index: 55.1800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.2190
Cell Significance Index: 98.1500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.9356
Cell Significance Index: 73.3000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.8222
Cell Significance Index: 111.7200 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.4851
Cell Significance Index: 16.8700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.4618
Cell Significance Index: 31.6700 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.9331
Cell Significance Index: 13.6000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.7990
Cell Significance Index: 9.9100 - Cell Name: granule cell (CL0000120)
Fold Change: 0.7523
Cell Significance Index: 8.5700 - Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
Fold Change: 0.6730
Cell Significance Index: 6.8000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5615
Cell Significance Index: 106.8600 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.5212
Cell Significance Index: 5.7500 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.4423
Cell Significance Index: 4.9100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4064
Cell Significance Index: 145.7900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3526
Cell Significance Index: 70.7400 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.3092
Cell Significance Index: 4.0100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2743
Cell Significance Index: 27.1400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2658
Cell Significance Index: 239.9700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.2151
Cell Significance Index: 4.5800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1927
Cell Significance Index: 20.9700 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.1917
Cell Significance Index: 1.5800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1907
Cell Significance Index: 11.4500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1782
Cell Significance Index: 4.6900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1628
Cell Significance Index: 26.4900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1430
Cell Significance Index: 6.4800 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.1371
Cell Significance Index: 1.7100 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.1212
Cell Significance Index: 1.4700 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: 0.1195
Cell Significance Index: 1.3100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0915
Cell Significance Index: 2.6100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0882
Cell Significance Index: 6.1000 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.0618
Cell Significance Index: 1.3400 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: 0.0420
Cell Significance Index: 0.5300 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: 0.0188
Cell Significance Index: 0.2500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0090
Cell Significance Index: 0.4700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0083
Cell Significance Index: 0.2000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0068
Cell Significance Index: 0.1700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.0039
Cell Significance Index: 2.8600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.0037
Cell Significance Index: 2.1100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0031
Cell Significance Index: 0.1900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.0019
Cell Significance Index: 0.0600 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.0016
Cell Significance Index: 0.0400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0013
Cell Significance Index: 2.4200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0006
Cell Significance Index: 0.0200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0003
Cell Significance Index: 0.0100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0006
Cell Significance Index: -0.4000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0012
Cell Significance Index: -2.2900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0016
Cell Significance Index: -2.3900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0024
Cell Significance Index: -3.2000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0027
Cell Significance Index: -0.5600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0066
Cell Significance Index: -0.1300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0069
Cell Significance Index: -1.1700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0069
Cell Significance Index: -3.0600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0079
Cell Significance Index: -5.9700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0085
Cell Significance Index: -4.6400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0091
Cell Significance Index: -0.1300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0096
Cell Significance Index: -6.0900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0106
Cell Significance Index: -4.8300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0144
Cell Significance Index: -0.2900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0152
Cell Significance Index: -4.3700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0215
Cell Significance Index: -2.4500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0254
Cell Significance Index: -5.0400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0270
Cell Significance Index: -4.8600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0322
Cell Significance Index: -0.4400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0336
Cell Significance Index: -0.9400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0337
Cell Significance Index: -0.7000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0351
Cell Significance Index: -5.1000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0351
Cell Significance Index: -4.8200 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.0356
Cell Significance Index: -0.5400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0434
Cell Significance Index: -5.0600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0442
Cell Significance Index: -5.0600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0445
Cell Significance Index: -5.4700 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0478
Cell Significance Index: -0.6800 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0498
Cell Significance Index: -0.7500 - Cell Name: neuron (CL0000540)
Fold Change: -0.0506
Cell Significance Index: -0.4800 - Cell Name: neural cell (CL0002319)
Fold Change: -0.0506
Cell Significance Index: -0.5900 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.0524
Cell Significance Index: -0.7400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0535
Cell Significance Index: -3.6000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0547
Cell Significance Index: -1.1600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0562
Cell Significance Index: -1.8400 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.0577
Cell Significance Index: -0.6900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0612
Cell Significance Index: -6.3700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0622
Cell Significance Index: -7.3400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0631
Cell Significance Index: -2.2100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0669
Cell Significance Index: -3.1200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0681
Cell Significance Index: -6.9600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0685
Cell Significance Index: -5.2600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0750
Cell Significance Index: -4.2100 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0762
Cell Significance Index: -1.5000 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.0805
Cell Significance Index: -1.1300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0866
Cell Significance Index: -5.4600 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0900
Cell Significance Index: -0.9800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1100
Cell Significance Index: -5.7300 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.1167
Cell Significance Index: -1.1100 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.1183
Cell Significance Index: -2.3600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1223
Cell Significance Index: -4.4900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1249
Cell Significance Index: -3.2100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1294
Cell Significance Index: -6.0800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2348027017
Symbol: GRM4_HUMAN
Name: Metabotropic glutamate receptor 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8738157
Title: Molecular characterization and localization of human metabotropic glutamate receptor type 4.
PubMed ID: 8738157
PubMed ID: 9473604
Title: Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.
PubMed ID: 9473604
PubMed ID: 7617140
Title: Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 4.
PubMed ID: 7617140
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 11525421
Title: Mutation screening of the metabotropic glutamate receptor mGluR4 (GRM4) gene in patients with schizophrenia.
PubMed ID: 11525421
Sequence Information:
- Length: 912
- Mass: 101868
- Checksum: 4A2F36E63A2EAF5A
- Sequence:
MPGKRGLGWW WARLPLCLLL SLYGPWMPSS LGKPKGHPHM NSIRIDGDIT LGGLFPVHGR GSEGKPCGEL KKEKGIHRLE AMLFALDRIN NDPDLLPNIT LGARILDTCS RDTHALEQSL TFVQALIEKD GTEVRCGSGG PPIITKPERV VGVIGASGSS VSIMVANILR LFKIPQISYA STAPDLSDNS RYDFFSRVVP SDTYQAQAMV DIVRALKWNY VSTVASEGSY GESGVEAFIQ KSREDGGVCI AQSVKIPREP KAGEFDKIIR RLLETSNARA VIIFANEDDI RRVLEAARRA NQTGHFFWMG SDSWGSKIAP VLHLEEVAEG AVTILPKRMS VRGFDRYFSS RTLDNNRRNI WFAEFWEDNF HCKLSRHALK KGSHVKKCTN RERIGQDSAY EQEGKVQFVI DAVYAMGHAL HAMHRDLCPG RVGLCPRMDP VDGTQLLKYI RNVNFSGIAG NPVTFNENGD APGRYDIYQY QLRNDSAEYK VIGSWTDHLH LRIERMHWPG SGQQLPRSIC SLPCQPGERK KTVKGMPCCW HCEPCTGYQY QVDRYTCKTC PYDMRPTENR TGCRPIPIIK LEWGSPWAVL PLFLAVVGIA ATLFVVITFV RYNDTPIVKA SGRELSYVLL AGIFLCYATT FLMIAEPDLG TCSLRRIFLG LGMSISYAAL LTKTNRIYRI FEQGKRSVSA PRFISPASQL AITFSLISLQ LLGICVWFVV DPSHSVVDFQ DQRTLDPRFA RGVLKCDISD LSLICLLGYS MLLMVTCTVY AIKTRGVPET FNEAKPIGFT MYTTCIVWLA FIPIFFGTSQ SADKLYIQTT TLTVSVSLSA SVSLGMLYMP KVYIILFHPE QNVPKRKRSL KAVVTAATMS NKFTQKGNFR PNGEAKSELC ENLEAPALAT KQTYVTYTNH AI
Genular Protein ID: 1651099849
Symbol: A8K0J8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 604
- Mass: 67999
- Checksum: B99356631C935F16
- Sequence:
MGSDSWGSKI APVLHLEEVA EGAVTILPKR MSVRGFDRYF SSRTLDNNRR NIWFAEFWED NFHCKLSRHA LKKGSHVKKC TNRERIGQDS AYEQEGKVQF VIDAVYAMGH ALHAMHRDLC PGRVGLCPRM DPVDGTQLLK YIRNVNFSGI AGNPVTFNEN GDAPGRYDIY QYQLRNDSAE YKVIGSWTDH LHLRIERMHW PGSGQQLPRS ICSLPCQPGE RKKTVKGMPC CWHCEPCTGY QYQVDRYTCK TCPYDMRPTE NRTGCRPIPI IKLEWGSPWA VLPLFLAVVG IAATLFVVIT FVRYNDTPIV KASGRELSYV LLAGIFLCYA TTFLMIAEPD LGTCSLRRIF LGLGMSISYA ALLTKTNRIY RIFEQGKRSV SAPRFISPAS QLAITFSLIS LQLLGICVWF VVDPSHSVVD FQDQRTLDPR FARGVLKCDI SDLSLICLLG YSMLLMVTCT VYAIKTRGVP ETFNEAKPIG FTMYTTCIVW LAFIPIFFGT SQSADKLYIQ TTTLTVSVSL SASVSLGMLY MPKVYIILFH PEQNVPKRKR SLKAVVTAAT MSNKFTQKGN FRPNGEAKSE LCENLEAPAL ATKQTYVTYT NHAI
Genular Protein ID: 3990698199
Symbol: B7ZLU9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 865
- Mass: 96139
- Checksum: 6166A86C8E3865A0
- Sequence:
MPGKRGLGWW WARLPLCLLL SLYGPWMPSS LGKPKGHPHM NSIRIDGDIT LGGLFPVHGR GSEGKPCGEL KKEKGIHRLE AMLFALDRIN NDPDLLPNIT LGARILDTCS RDTHALEQSL TFVQALIEKD GTEVRCGSGG PPIITKPERV VGVIGASGSS VSIMVANILR LFKIPQISYA STAPDLSDNS RYDFFSRVVP SDTYQAQAMV DIVRALKWNY VSTVASEGSY GESGVEAFIQ KSREDGGVCI AQSVKIPREP KAGEFDKIIR RLLETSNARA VIIFANEDDI RRVLEAARRA NQTGHFFWMG SDSWGSKIAP VLHLEEVAEG AVTILPKRMS VRDRERIGQD SAYEQEGKVQ FVIDAVYAMG HALHAMHRDL CPGRVGLCPR MDPVDGTQLL KYIRNVNFSG IAGNPVTFNE NGDAPGRYDI YQYQLRNDSA EYKVIGSWTD HLHLRIERMH WPGSGQQLPR SICSLPCQPG ERKKTVKGMP CCWHCEPCTG YQYQVDRYTC KTCPYDMRPT ENRTGCRPIP IIKLEWGSPW AVLPLFLAVV GIAATLFVVI TFVRYNDTPI VKASGRELSY VLLAGIFLCY ATTFLMIAEP DLGTCSLRRI FLGLGMSISY AALLTKTNRI YRIFEQGKRS VSAPRFISPA SQLAITFSLI SLQLLGICVW FVVDPSHSVV DFQDQRTLDP RFARGVLKCD ISDLSLICLL GYSMLLMVTC TVYAIKTRGV PETFNEAKPI GFTMYTTCIV WLAFIPIFFG TSQSADKLYI QTTTLTVSVS LSASVSLGML YMPKVYIILF HPEQNVPKRK RSLKAVVTAA TMSNKFTQKG NFRPNGEAKS ELCENLEAPA LATKQTYVTY TNHAI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.