Details for: SERPIND1

Gene ID: 3053

Symbol: SERPIND1

Ensembl ID: ENSG00000099937

Description: serpin family D member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 15.2747
    Cell Significance Index: 256.9100
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: 3.5014
    Cell Significance Index: 56.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.8126
    Cell Significance Index: 39.2700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5455
    Cell Significance Index: 306.7100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.3628
    Cell Significance Index: 259.3400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0234
    Cell Significance Index: 101.2400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9039
    Cell Significance Index: 816.1900
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 0.8112
    Cell Significance Index: 2.1400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.8077
    Cell Significance Index: 13.6100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.5867
    Cell Significance Index: 8.6600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.4626
    Cell Significance Index: 11.2100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4622
    Cell Significance Index: 75.1700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4548
    Cell Significance Index: 9.6900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4500
    Cell Significance Index: 48.9500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.4355
    Cell Significance Index: 13.9500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.3271
    Cell Significance Index: 4.6900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2497
    Cell Significance Index: 17.2700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2164
    Cell Significance Index: 4.6300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.2088
    Cell Significance Index: 2.7900
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.1928
    Cell Significance Index: 2.0000
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.1719
    Cell Significance Index: 0.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1686
    Cell Significance Index: 2.8900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1422
    Cell Significance Index: 2.9500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1411
    Cell Significance Index: 97.6000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1359
    Cell Significance Index: 8.1600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1072
    Cell Significance Index: 3.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1049
    Cell Significance Index: 21.0400
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.0560
    Cell Significance Index: 0.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0422
    Cell Significance Index: 1.0800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0333
    Cell Significance Index: 4.8400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0327
    Cell Significance Index: 1.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0278
    Cell Significance Index: 1.2300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0208
    Cell Significance Index: 0.5200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0185
    Cell Significance Index: 0.6500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0151
    Cell Significance Index: 5.4100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0129
    Cell Significance Index: 23.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0091
    Cell Significance Index: 14.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0076
    Cell Significance Index: 0.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0061
    Cell Significance Index: 11.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0034
    Cell Significance Index: 0.1900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0033
    Cell Significance Index: 4.4700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0031
    Cell Significance Index: 0.1400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0022
    Cell Significance Index: 1.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0015
    Cell Significance Index: 0.2700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0011
    Cell Significance Index: -0.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0024
    Cell Significance Index: -1.5000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0029
    Cell Significance Index: -0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0035
    Cell Significance Index: -2.5800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0045
    Cell Significance Index: -2.0200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0069
    Cell Significance Index: -3.8700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0073
    Cell Significance Index: -0.1100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0074
    Cell Significance Index: -4.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0077
    Cell Significance Index: -4.8100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0085
    Cell Significance Index: -0.5700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0090
    Cell Significance Index: -1.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0124
    Cell Significance Index: -3.5700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0148
    Cell Significance Index: -0.6400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0168
    Cell Significance Index: -1.0300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0197
    Cell Significance Index: -0.2800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0216
    Cell Significance Index: -4.5600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0222
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0229
    Cell Significance Index: -3.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0233
    Cell Significance Index: -1.4300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0278
    Cell Significance Index: -3.8200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0332
    Cell Significance Index: -3.8700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0337
    Cell Significance Index: -3.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0349
    Cell Significance Index: -3.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0392
    Cell Significance Index: -4.5000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0395
    Cell Significance Index: -5.1000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0449
    Cell Significance Index: -1.4200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0492
    Cell Significance Index: -0.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0494
    Cell Significance Index: -1.3000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0500
    Cell Significance Index: -2.5200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0521
    Cell Significance Index: -1.4000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0525
    Cell Significance Index: -0.6600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0608
    Cell Significance Index: -1.7000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0609
    Cell Significance Index: -3.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0622
    Cell Significance Index: -3.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0667
    Cell Significance Index: -3.1100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0671
    Cell Significance Index: -5.0000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0697
    Cell Significance Index: -2.4400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0721
    Cell Significance Index: -0.9100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0722
    Cell Significance Index: -2.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0754
    Cell Significance Index: -2.4700
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0832
    Cell Significance Index: -1.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0839
    Cell Significance Index: -4.4100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0896
    Cell Significance Index: -4.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0922
    Cell Significance Index: -5.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0946
    Cell Significance Index: -4.9300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0952
    Cell Significance Index: -2.5900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0959
    Cell Significance Index: -1.1900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0971
    Cell Significance Index: -2.0600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1004
    Cell Significance Index: -2.6800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.1004
    Cell Significance Index: -1.6100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1060
    Cell Significance Index: -2.2900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1061
    Cell Significance Index: -2.2200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1103
    Cell Significance Index: -1.5300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1151
    Cell Significance Index: -4.2300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1159
    Cell Significance Index: -2.7800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1191
    Cell Significance Index: -2.9700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Serpin Family Member:** SERPIND1 belongs to the serpin family of protease inhibitors, which are characterized by their ability to bind to serine proteases and inhibit their activity. 2. **Multifunctional Protein:** SERPIND1 has been shown to have multiple functions, including endopeptidase inhibitor activity, negative regulation of endopeptidase activity, and post-translational protein modification. 3. **Wide Expression:** SERPIND1 is expressed in various cell types, including retina cells, hepatoblasts, conventional dendritic cells, enterocytes, and colon goblet cells. 4. **Heparin Binding:** SERPIND1 has been shown to bind to heparin, a glycosaminoglycan that plays a role in various biological processes, including blood coagulation and chemotaxis. **Pathways and Functions:** 1. **Blood Coagulation:** SERPIND1 plays a crucial role in the blood coagulation cascade, particularly in the intrinsic pathway of fibrin clot formation. 2. **Chemotaxis:** SERPIND1 has been shown to regulate chemotaxis, the movement of cells in response to chemical stimuli. 3. **Fibrin Clot Formation:** SERPIND1 is involved in the formation of fibrin clots, which are essential for wound healing and hemostasis. 4. **Endopeptidase Inhibition:** SERPIND1 inhibits endopeptidase activity, which is involved in various cellular processes, including protein degradation and signal transduction. 5. **Post-translational Protein Modification:** SERPIND1 regulates post-translational protein modification, including phosphorylation and ubiquitination. **Clinical Significance:** 1. **Blood Coagulation Disorders:** Alterations in SERPIND1 expression have been linked to blood coagulation disorders, such as deep vein thrombosis and pulmonary embolism. 2. **Neurological Disorders:** SERPIND1 has been implicated in various neurological disorders, including Alzheimer's disease and Parkinson's disease, where its dysregulation may contribute to disease progression. 3. **Cancer:** SERPIND1 has been shown to have a role in cancer progression, particularly in the regulation of insulin-like growth factor (IGF) transport and uptake by insulin-like growth factor binding proteins (IGFBPs). 4. **Immune System Dysfunction:** Alterations in SERPIND1 expression have been linked to immune system dysfunction, including autoimmune diseases and immunodeficiency disorders. In conclusion, SERPIND1 is a multifaceted gene involved in various biological processes, including blood coagulation, chemotaxis, and fibrin clot formation. Its dysregulation has been linked to various diseases, highlighting the importance of its proper expression and function in maintaining cellular homeostasis.

Genular Protein ID: 1165129662

Symbol: HEP2_HUMAN

Name: Heparin cofactor 2

UniProtKB Accession Codes:

P05546 A0A7H0TJC6 B2RAI1 D3DX34 Q6IBZ5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CPTAC 2 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 8 EMBL 9 Ensembl 2 EvolutionaryTrace 1 GO 9 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2894851

Title: Heparin cofactor II: cDNA sequence, chromosome localization, restriction fragment length polymorphism, and expression in Escherichia coli.

PubMed ID: 2894851

DOI: 10.1021/bi00402a039

PubMed ID: 32827448

Title: Identification and characterization of a novel isoform of heparin cofactor II in human liver.

PubMed ID: 32827448

DOI: 10.1002/iub.2361

PubMed ID: 1671335

Title: Complete nucleotide sequence of the gene for human heparin cofactor II and mapping to chromosomal band 22q11.

PubMed ID: 1671335

DOI: 10.1021/bi00219a027

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 3003690

Title: A new member of the plasma protease inhibitor gene family.

PubMed ID: 3003690

DOI: 10.1093/nar/14.2.1073

PubMed ID: 3755044

Title: Isolation and characterization of a partial cDNA clone for heparin cofactor II1.

PubMed ID: 3755044

DOI: 10.1016/0006-291x(86)91228-3

PubMed ID: 3907702

Title: Structural evidence for leucine at the reactive site of heparin cofactor II.

PubMed ID: 3907702

DOI: 10.1021/bi00345a008

PubMed ID: 2841345

Title: Structure and expression of the gene coding for the human serpin hLS2.

PubMed ID: 2841345

DOI: 10.1016/s0021-9258(18)37902-x

PubMed ID: 1985958

Title: Leukocyte chemoattractant peptides from the serpin heparin cofactor II.

PubMed ID: 1985958

DOI: 10.1016/s0021-9258(17)35228-6

PubMed ID: 1939083

Title: The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans.

PubMed ID: 1939083

DOI: 10.1016/s0021-9258(18)54913-9

PubMed ID: 2104620

Title: Site-directed mutagenesis of arginine 103 and lysine 185 in the proposed glycosaminoglycan-binding site of heparin cofactor II.

PubMed ID: 2104620

DOI: 10.1016/s0021-9258(19)40228-7

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 12169660

Title: Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.

PubMed ID: 12169660

DOI: 10.1073/pnas.162232399

PubMed ID: 2647747

Title: Heparin cofactor IIOslo. Mutation of Arg-189 to His decreases the affinity for dermatan sulfate.

PubMed ID: 2647747

DOI: 10.1016/s0021-9258(18)83708-5

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

PubMed ID: 11204559

Title: Molecular mechanism of type I congenital heparin cofactor (HC) II deficiency caused by a missense mutation at reactive P2 site: HC II Tokushima.

PubMed ID: 11204559

PubMed ID: 15337701

Title: Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis.

PubMed ID: 15337701

DOI: 10.1161/01.cir.0000140763.51679.d9

Sequence Information:

  • Length: 499
  • Mass: 57071
  • Checksum: 3B0E353FE1F6DF05
  • Sequence:
    • MKHSLNALLI FLIITSAWGG SKGPLDQLEK GGETAQSADP QWEQLNNKNL SMPLLPADFH 
KENTVTNDWI PEGEEDDDYL DLEKIFSEDD DYIDIVDSLS VSPTDSDVSA GNILQLFHGK 
SRIQRLNILN AKFAFNLYRV LKDQVNTFDN IFIAPVGIST AMGMISLGLK GETHEQVHSI 
LHFKDFVNAS SKYEITTIHN LFRKLTHRLF RRNFGYTLRS VNDLYIQKQF PILLDFKTKV 
REYYFAEAQI ADFSDPAFIS KTNNHIMKLT KGLIKDALEN IDPATQMMIL NCIYFKGSWV 
NKFPVEMTHN HNFRLNEREV VKVSMMQTKG NFLAANDQEL DCDILQLEYV GGISMLIVVP 
HKMSGMKTLE AQLTPRVVER WQKSMTNRTR EVLLPKFKLE KNYNLVESLK LMGIRMLFDK 
NGNMAGISDQ RIAIDLFKHQ GTITVNEEGT QATTVTTVGF MPLSTQVRFT VDRPFLFLIY 
EHRTSCLLFM GRVANPSRS

Genular Protein ID: 953020103

Symbol: Q8IVC0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8IVC0

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 2 InterPro 7 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 499
  • Mass: 56957
  • Checksum: D20047E38655004F
  • Sequence:
    • MKHSLNALLI FLIITSAWGG SKGPLDQLEK GGETAQSADP QWEQLNNKNL SMPLLPADFH 
KENTVTNDWI PEGEEDDDYL DLEKIFSEDD DYIDIVDSLS VSPTDSDVSA GNILQLFHGK 
SRIQRLNIVN AKFAFNLYRV LKDQVNTFDN IFIAPVGIST AMGMISLGLK GETHEQVHSI 
LHFKDFVNAS SKYEITTIHN LFRKLTHRLF RRNFGYTLRS VNDLYIQKQF PILLDFKTKV 
REYYFAEAQI ADFSDPAFIS KTNNHIMKLT KGLIKDALEN IDPATQMMIL NCIYFKGSWV 
NKFPVEMTHN HNFRLNEREV VKVSMMQTKG NFLAANDQEL DCDILQLEYV GGISMLIVVP 
HKMSGMKTLE AQLTPGVVER WQKSMTNRTR EVLLPKFKLE KNYNLVESLK LMGIRMLFDK 
NGNMAGISDQ RIAIDLFKHQ GTITVNEEGT QATTVTTVGF MPLSTQVRFT VDRPFLFLIY 
EHRTSCLLFM GRVANPSRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.