Details for: SERPIND1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 5.75
Marker Score: 16773 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 4.91
Marker Score: 14569 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 4.73
Marker Score: 4531.5 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 3.98
Marker Score: 11433 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 3.51
Marker Score: 29667 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 2.58
Marker Score: 7349 - Cell Name: hepatoblast (CL0005026)
Fold Change: 2.21
Marker Score: 7233 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 2.2
Marker Score: 1514 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2
Marker Score: 1997 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1172 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.37
Marker Score: 872 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.27
Marker Score: 857 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4817 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.1
Marker Score: 6694 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.1
Marker Score: 505 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.02
Marker Score: 4405 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71829 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48054 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 511 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.98
Marker Score: 408 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 464 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30408 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2412 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.94
Marker Score: 375 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5340 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.92
Marker Score: 849 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2742 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 327 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.87
Marker Score: 13608 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.87
Marker Score: 1644 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.82
Marker Score: 628 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1262 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 398 - Cell Name: brush cell (CL0002204)
Fold Change: 0.76
Marker Score: 697 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.73
Marker Score: 464 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.72
Marker Score: 3848 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.7
Marker Score: 264 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 179 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.69
Marker Score: 4465 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.65
Marker Score: 1319 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.61
Marker Score: 2345 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.57
Marker Score: 458 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.56
Marker Score: 148 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.55
Marker Score: 5562.5 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.47
Marker Score: 284 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.46
Marker Score: 314 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 0.45
Marker Score: 701 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.44
Marker Score: 186 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.43
Marker Score: 656 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.42
Marker Score: 106 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.41
Marker Score: 398 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.39
Marker Score: 114 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.37
Marker Score: 373 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.36
Marker Score: 390.5 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.36
Marker Score: 224 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.35
Marker Score: 719.5 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.34
Marker Score: 92 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.32
Marker Score: 102 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.29
Marker Score: 108 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.29
Marker Score: 142 - Cell Name: erythrocyte (CL0000232)
Fold Change: 0.28
Marker Score: 154 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.27
Marker Score: 131 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.27
Marker Score: 1822 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.27
Marker Score: 1604 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.26
Marker Score: 110 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.26
Marker Score: 343 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.25
Marker Score: 128.5 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.25
Marker Score: 100 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.24
Marker Score: 380 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.24
Marker Score: 211 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.23
Marker Score: 91 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.22
Marker Score: 64 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.22
Marker Score: 74 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.21
Marker Score: 210 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: 0.21
Marker Score: 64 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.2
Marker Score: 371 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.2
Marker Score: 89 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.2
Marker Score: 118 - Cell Name: monocyte (CL0000576)
Fold Change: 0.2
Marker Score: 255 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.18
Marker Score: 221 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.18
Marker Score: 181 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.18
Marker Score: 10845 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.18
Marker Score: 218 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 0.17
Marker Score: 915 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.17
Marker Score: 1493 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.17
Marker Score: 101.5 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.17
Marker Score: 43 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.17
Marker Score: 1591 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 0.17
Marker Score: 46 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.17
Marker Score: 53 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.17
Marker Score: 206 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.16
Marker Score: 656 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.15
Marker Score: 2486 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.15
Marker Score: 81 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.15
Marker Score: 985 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.14
Marker Score: 59 - Cell Name: podocyte (CL0000653)
Fold Change: 0.14
Marker Score: 53 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.14
Marker Score: 81 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.14
Marker Score: 57 - Cell Name: pneumocyte (CL0000322)
Fold Change: 0.14
Marker Score: 223
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Other Information
Genular Protein ID: 1165129662
Symbol: HEP2_HUMAN
Name: Heparin cofactor 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2894851
Title: Heparin cofactor II: cDNA sequence, chromosome localization, restriction fragment length polymorphism, and expression in Escherichia coli.
PubMed ID: 2894851
DOI: 10.1021/bi00402a039
PubMed ID: 1671335
Title: Complete nucleotide sequence of the gene for human heparin cofactor II and mapping to chromosomal band 22q11.
PubMed ID: 1671335
DOI: 10.1021/bi00219a027
PubMed ID: 15461802
Title: A genome annotation-driven approach to cloning the human ORFeome.
PubMed ID: 15461802
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 3003690
Title: A new member of the plasma protease inhibitor gene family.
PubMed ID: 3003690
PubMed ID: 3755044
Title: Isolation and characterization of a partial cDNA clone for heparin cofactor II1.
PubMed ID: 3755044
PubMed ID: 3907702
Title: Structural evidence for leucine at the reactive site of heparin cofactor II.
PubMed ID: 3907702
DOI: 10.1021/bi00345a008
PubMed ID: 2841345
Title: Structure and expression of the gene coding for the human serpin hLS2.
PubMed ID: 2841345
PubMed ID: 1985958
Title: Leukocyte chemoattractant peptides from the serpin heparin cofactor II.
PubMed ID: 1985958
PubMed ID: 1939083
Title: The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans.
PubMed ID: 1939083
PubMed ID: 2104620
Title: Site-directed mutagenesis of arginine 103 and lysine 185 in the proposed glycosaminoglycan-binding site of heparin cofactor II.
PubMed ID: 2104620
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 12169660
Title: Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
PubMed ID: 12169660
PubMed ID: 2647747
Title: Heparin cofactor IIOslo. Mutation of Arg-189 to His decreases the affinity for dermatan sulfate.
PubMed ID: 2647747
PubMed ID: 10391209
Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.
PubMed ID: 10391209
DOI: 10.1038/10290
PubMed ID: 11204559
Title: Molecular mechanism of type I congenital heparin cofactor (HC) II deficiency caused by a missense mutation at reactive P2 site: HC II Tokushima.
PubMed ID: 11204559
PubMed ID: 15337701
Title: Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis.
PubMed ID: 15337701
Sequence Information:
- Length: 499
- Mass: 57071
- Checksum: 3B0E353FE1F6DF05
- Sequence:
MKHSLNALLI FLIITSAWGG SKGPLDQLEK GGETAQSADP QWEQLNNKNL SMPLLPADFH KENTVTNDWI PEGEEDDDYL DLEKIFSEDD DYIDIVDSLS VSPTDSDVSA GNILQLFHGK SRIQRLNILN AKFAFNLYRV LKDQVNTFDN IFIAPVGIST AMGMISLGLK GETHEQVHSI LHFKDFVNAS SKYEITTIHN LFRKLTHRLF RRNFGYTLRS VNDLYIQKQF PILLDFKTKV REYYFAEAQI ADFSDPAFIS KTNNHIMKLT KGLIKDALEN IDPATQMMIL NCIYFKGSWV NKFPVEMTHN HNFRLNEREV VKVSMMQTKG NFLAANDQEL DCDILQLEYV GGISMLIVVP HKMSGMKTLE AQLTPRVVER WQKSMTNRTR EVLLPKFKLE KNYNLVESLK LMGIRMLFDK NGNMAGISDQ RIAIDLFKHQ GTITVNEEGT QATTVTTVGF MPLSTQVRFT VDRPFLFLIY EHRTSCLLFM GRVANPSRS
Genular Protein ID: 953020103
Symbol: Q8IVC0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 499
- Mass: 56957
- Checksum: D20047E38655004F
- Sequence:
MKHSLNALLI FLIITSAWGG SKGPLDQLEK GGETAQSADP QWEQLNNKNL SMPLLPADFH KENTVTNDWI PEGEEDDDYL DLEKIFSEDD DYIDIVDSLS VSPTDSDVSA GNILQLFHGK SRIQRLNIVN AKFAFNLYRV LKDQVNTFDN IFIAPVGIST AMGMISLGLK GETHEQVHSI LHFKDFVNAS SKYEITTIHN LFRKLTHRLF RRNFGYTLRS VNDLYIQKQF PILLDFKTKV REYYFAEAQI ADFSDPAFIS KTNNHIMKLT KGLIKDALEN IDPATQMMIL NCIYFKGSWV NKFPVEMTHN HNFRLNEREV VKVSMMQTKG NFLAANDQEL DCDILQLEYV GGISMLIVVP HKMSGMKTLE AQLTPGVVER WQKSMTNRTR EVLLPKFKLE KNYNLVESLK LMGIRMLFDK NGNMAGISDQ RIAIDLFKHQ GTITVNEEGT QATTVTTVGF MPLSTQVRFT VDRPFLFLIY EHRTSCLLFM GRVANPSRS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.