Details for: MUC6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 30.7209
Cell Significance Index: 766.0900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 15.5096
Cell Significance Index: 422.1600 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 4.9018
Cell Significance Index: 23.3500 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 3.7288
Cell Significance Index: 43.3500 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 1.5971
Cell Significance Index: 6.0200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.4941
Cell Significance Index: -3.2700 - Cell Name: duodenum glandular cell (CL1001589)
Fold Change: 1.4574
Cell Significance Index: 10.4400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.4487
Cell Significance Index: 7.6900 - Cell Name: helper T cell (CL0000912)
Fold Change: 0.3420
Cell Significance Index: 4.8600 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.2127
Cell Significance Index: 1.8900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.2087
Cell Significance Index: 23.9200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2033
Cell Significance Index: 7.7000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1791
Cell Significance Index: 7.9200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1053
Cell Significance Index: 21.1200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0630
Cell Significance Index: 10.7500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0602
Cell Significance Index: 37.6000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0577
Cell Significance Index: 4.3000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.0357
Cell Significance Index: 1.1300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0136
Cell Significance Index: 7.4500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0136
Cell Significance Index: 18.4900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0083
Cell Significance Index: 1.6500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0025
Cell Significance Index: 0.9100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0003
Cell Significance Index: 0.5700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0010
Cell Significance Index: -1.9000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0015
Cell Significance Index: -2.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0046
Cell Significance Index: -3.3900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0087
Cell Significance Index: -4.8800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0109
Cell Significance Index: -8.2300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0114
Cell Significance Index: -3.2900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0115
Cell Significance Index: -7.2800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0157
Cell Significance Index: -1.8300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0163
Cell Significance Index: -0.4200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0218
Cell Significance Index: -9.9000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0225
Cell Significance Index: -4.7300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0280
Cell Significance Index: -1.4200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0285
Cell Significance Index: -5.1400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0412
Cell Significance Index: -5.9900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0419
Cell Significance Index: -4.7900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0488
Cell Significance Index: -6.0100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0503
Cell Significance Index: -0.7200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0567
Cell Significance Index: -7.7900 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: -0.0576
Cell Significance Index: -0.7300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0670
Cell Significance Index: -8.6500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0713
Cell Significance Index: -7.2800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0751
Cell Significance Index: -5.7600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0775
Cell Significance Index: -8.0700 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0779
Cell Significance Index: -1.0200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0926
Cell Significance Index: -2.5900 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0949
Cell Significance Index: -1.4200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1076
Cell Significance Index: -5.6500 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1080
Cell Significance Index: -2.8400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1173
Cell Significance Index: -4.1100 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1215
Cell Significance Index: -1.8800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1295
Cell Significance Index: -7.9400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1331
Cell Significance Index: -4.2400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1401
Cell Significance Index: -1.6700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1424
Cell Significance Index: -2.9800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1552
Cell Significance Index: -8.7100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1584
Cell Significance Index: -5.1900 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.1650
Cell Significance Index: -2.8200 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1735
Cell Significance Index: -7.1100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1743
Cell Significance Index: -8.1900 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.1784
Cell Significance Index: -2.5900 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.1850
Cell Significance Index: -3.1900 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.1893
Cell Significance Index: -1.1700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1900
Cell Significance Index: -4.7400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1928
Cell Significance Index: -10.0200 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.2155
Cell Significance Index: -3.0700 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.2198
Cell Significance Index: -2.8300 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2267
Cell Significance Index: -6.0700 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.2377
Cell Significance Index: -10.3400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2449
Cell Significance Index: -8.9900 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.2461
Cell Significance Index: -3.3700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2527
Cell Significance Index: -5.4600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2614
Cell Significance Index: -7.7000 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.2615
Cell Significance Index: -5.3200 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2688
Cell Significance Index: -5.6100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.2723
Cell Significance Index: -2.9600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.2743
Cell Significance Index: -9.6400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2747
Cell Significance Index: -5.8300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2869
Cell Significance Index: -5.7600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2893
Cell Significance Index: -13.4900 - Cell Name: myoblast (CL0000056)
Fold Change: -0.3033
Cell Significance Index: -2.9800 - Cell Name: osteoblast (CL0000062)
Fold Change: -0.3061
Cell Significance Index: -2.9700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3094
Cell Significance Index: -8.8700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.3101
Cell Significance Index: -8.3100 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3225
Cell Significance Index: -9.4700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3225
Cell Significance Index: -8.6100 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.3263
Cell Significance Index: -4.4800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3272
Cell Significance Index: -6.4700 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.3308
Cell Significance Index: -4.6400 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.3330
Cell Significance Index: -2.8800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3401
Cell Significance Index: -9.8000 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3407
Cell Significance Index: -5.8900 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.3451
Cell Significance Index: -2.2500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.3470
Cell Significance Index: -6.8300 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.3520
Cell Significance Index: -5.9200 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.3542
Cell Significance Index: -8.5800 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.3587
Cell Significance Index: -9.1400 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.3590
Cell Significance Index: -5.9200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1915647275
Symbol: MUC6_HUMAN
Name: Mucin-6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15081123
Title: The complete genomic organization of the human MUC6 and MUC2 mucin genes.
PubMed ID: 15081123
PubMed ID: 7680650
Title: Human gastric mucin. Identification of a unique species by expression cloning.
PubMed ID: 7680650
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 9195947
Title: The carboxyl-terminal sequence of the human secretory mucin, MUC6. Analysis of the primary amino acid sequence.
PubMed ID: 9195947
PubMed ID: 9422745
Title: Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs.
PubMed ID: 9422745
PubMed ID: 10209489
Title: The MUC6 secretory mucin gene is expressed in a wide variety of epithelial tissues.
PubMed ID: 10209489
DOI: 10.1002/(sici)1096-9896(199812)186:4<398::aid-path192>3.0.co;2-x
PubMed ID: 10330458
Title: Expression of the MUC 6 mucin gene in development of the human kidney and male genital ducts.
PubMed ID: 10330458
PubMed ID: 11988092
Title: Gastric MUC5AC and MUC6 are large oligomeric mucins that differ in size, glycosylation and tissue distribution.
PubMed ID: 11988092
DOI: 10.1042/bj3640191
PubMed ID: 15280409
Title: Aberrant epithelial expression of trefoil family factor 2 and mucin 6 in Helicobacter pylori infected gastric antrum, incisura, and body and its association with antralisation.
PubMed ID: 15280409
PubMed ID: 15979574
Title: Upregulation of MUC6 mucin gene expression by NFkappaB and Sp factors.
PubMed ID: 15979574
Sequence Information:
- Length: 2439
- Mass: 257051
- Checksum: 4A1A7E6A7C30F895
- Sequence:
MVQRWLLLSC CGALLSAGLA NTSYTSPGLQ RLKDSPQTAP DKGQCSTWGA GHFSTFDHHV YDFSGTCNYI FAATCKDAFP TFSVQLRRGP DGSISRIIVE LGASVVTVSE AIISVKDIGV ISLPYTSNGL QITPFGQSVR LVAKQLELEL EVVWGPDSHL MVLVERKYMG QMCGLCGNFD GKVTNEFVSE EGKFLEPHKF AALQKLDDPG EICTFQDIPS THVRQAQHAR ICTQLLTLVA PECSVSKEPF VLSCQADVAA APQPGPQNSS CATLSEYSRQ CSMVGQPVRR WRSPGLCSVG QCPANQVYQE CGSACVKTCS NPQHSCSSSC TFGCFCPEGT VLNDLSNNHT CVPVTQCPCV LHGAMYAPGE VTIAACQTCR CTLGRWVCTE RPCPGHCSLE GGSFVTTFDA RPYRFHGTCT YILLQSPQLP EDGALMAVYD KSGVSHSETS LVAVVYLSRQ DKIVISQDEV VTNNGEAKWL PYKTRNITVF RQTSTHLQMA TSFGLELVVQ LRPIFQAYVT VGPQFRGQTR GLCGNFNGDT TDDFTTSMGI AEGTASLFVD SWRAGNCPAA LERETDPCSM SQLNKVCAET HCSMLLRTGT VFERCHATVN PAPFYKRCVY QACNYEETFP HICAALGDYV HACSLRGVLL WGWRSSVDNC TIPCTGNTTF SYNSQACERT CLSLSDRATE CHHSAVPVDG CNCPDGTYLN QKGECVRKAQ CPCILEGYKF ILAEQSTVIN GITCHCINGR LSCPQRPQMF LASCQAPKTF KSCSQSSENK FGAACAPTCQ MLATGVACVP TKCEPGCVCA EGLYENADGQ CVPPEECPCE FSGVSYPGGA ELHTDCRTCS CSRGRWACQQ GTHCPSTCTL YGEGHVITFD GQRFVFDGNC EYILATDVCG VNDSQPTFKI LTENVICGNS GVTCSRAIKI FLGGLSVVLA DRNYTVTGEE PHVQLGVTPG ALSLVVDISI PGRYNLTLIW NRHMTILIRI ARASQDPLCG LCGNFNGNMK DDFETRSRYV ASSELELVNS WKESPLCGDV SFVTDPCSLN AFRRSWAERK CSVINSQTFA TCHSKVYHLP YYEACVRDAC GCDSGGDCEC LCDAVAAYAQ ACLDKGVCVD WRTPAFCPIY CGFYNTHTQD GHGEYQYTQE ANCTWHYQPC LCPSQPQSVP GSNIEGCYNC SQDEYFDHEE GVCVPCMPPT TPQPPTTPQL PTTGSRPTQV WPMTGTSTTI GLLSSTGPSP SSNHTPASPT QTPLLPATLT SSKPTASSGE PPRPTTAVTP QATSGLPPTA TLRSTATKPT VTQATTRATA STASPATTST AQSTTRTTMT LPTPATSGTS PTLPKSTNQE LPGTTATQTT GPRPTPASTT GPTTPQPGQP TRPTATETTQ TRTTTEYTTP QTPHTTHSPP TAGSPVPSTG PVTATSFHAT TTYPTPSHPE TTLPTHVPPF STSLVTPSTH TVITPTHAQM ATSASNHSAP TGTIPPPTTL KATGSTHTAP PITPTTSGTS QAHSSFSTNK TPTSLHSHTS STHHPEVTPT STTTITPNPT STRTRTPVAH TNSATSSRPP PPFTTHSPPT GSSPFSSTGP MTATSFKTTT TYPTPSHPQT TLPTHVPPFS TSLVTPSTHT VITPTHAQMA TSASIHSMPT GTIPPPTTLK ATGSTHTAPT MTLTTSGTSQ ALSSLNTAKT STSLHSHTSS THHAEATSTS TTNITPNPTS TGTPPMTVTT SGTSQSRSSF STAKTSTSLH SHTSSTHHPE VTSTSTTSIT PNHTSTGTRT PVAHTTSATS SRLPTPFTTH SPPTGTTPIS STGPVTATSF QTTTTYPTPS HPHTTLPTHV PSFSTSLVTP STHTVIIPTH TQMATSASIH SMPTGTIPPP TTIKATGSTH TAPPMTPTTS GTSQSPSSFS TAKTSTSLPY HTSSTHHPEV TPTSTTNITP KHTSTGTRTP VAHTTSASSS RLPTPFTTHS PPTGSSPFSS TGPMTATSFQ TTTTYPTPSH PQTTLPTHVP PFSTSLVTPS THTVIITTHT QMATSASIHS TPTGTVPPPT TLKATGSTHT APPMTVTTSG TSQTHSSFST ATASSSFISS SSWLPQNSSS RPPSSPITTQ LPHLSSATTP VSTTNQLSSS FSPSPSAPST VSSYVPSSHS SPQTSSPSVG TSSSFVSAPV HSTTLSSGSH SSLSTHPTTA SVSASPLFPS SPAASTTIRA TLPHTISSPF TLSALLPIST VTVSPTPSSH LASSTIAFPS TPRTTASTHT APAFSSQSTT SRSTSLTTRV PTSGFVSLTS GVTGIPTSPV TNLTTRHPGP TLSPTTRFLT SSLTAHGSTP ASAPVSSLGT PTPTSPGVCS VREQQEEITF KGCMANVTVT RCEGACISAA SFNIITQQVD ARCSCCRPLH SYEQQLELPC PDPSTPGRRL VLTLQVFSHC VCSSVACGD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.