Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 3.3823
Cell Significance Index: 35.3100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 2.4284
Cell Significance Index: 26.4000 - Cell Name: muscle precursor cell (CL0000680)
Fold Change: 1.2991
Cell Significance Index: 8.8800 - Cell Name: tongue muscle cell (CL0002673)
Fold Change: 0.9762
Cell Significance Index: 7.3100 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.2205
Cell Significance Index: 5.3400 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.1722
Cell Significance Index: 4.2900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1126
Cell Significance Index: 1.9300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.0512
Cell Significance Index: 0.7600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0501
Cell Significance Index: 10.0400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0388
Cell Significance Index: 13.9200 - Cell Name: fast muscle cell (CL0000190)
Fold Change: 0.0145
Cell Significance Index: 0.1900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0070
Cell Significance Index: 0.1800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0036
Cell Significance Index: 2.4800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0035
Cell Significance Index: 0.7000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0014
Cell Significance Index: 0.2400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0001
Cell Significance Index: -0.1300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0002
Cell Significance Index: -0.3500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0008
Cell Significance Index: -1.2900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0013
Cell Significance Index: -1.7200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0035
Cell Significance Index: -2.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0038
Cell Significance Index: -1.0800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0044
Cell Significance Index: -3.2800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0052
Cell Significance Index: -2.8600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0054
Cell Significance Index: -2.4500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0054
Cell Significance Index: -3.3600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0056
Cell Significance Index: -3.1400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0093
Cell Significance Index: -1.6800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0106
Cell Significance Index: -1.5400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0112
Cell Significance Index: -0.1600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0155
Cell Significance Index: -3.2600 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: -0.0212
Cell Significance Index: -0.2400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0225
Cell Significance Index: -0.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0235
Cell Significance Index: -2.8900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0261
Cell Significance Index: -3.0400 - Cell Name: radial glial cell (CL0000681)
Fold Change: -0.0270
Cell Significance Index: -0.1600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0270
Cell Significance Index: -3.0900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0284
Cell Significance Index: -2.9600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0348
Cell Significance Index: -2.3400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0375
Cell Significance Index: -2.8800 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: -0.0375
Cell Significance Index: -0.3100 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0412
Cell Significance Index: -0.5200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0430
Cell Significance Index: -1.9500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0504
Cell Significance Index: -3.1000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0511
Cell Significance Index: -2.8700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0511
Cell Significance Index: -1.3900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0532
Cell Significance Index: -2.4800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0561
Cell Significance Index: -2.4800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0568
Cell Significance Index: -1.5900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0574
Cell Significance Index: -2.7000 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0576
Cell Significance Index: -0.3900 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0593
Cell Significance Index: -0.9400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0597
Cell Significance Index: -2.0900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0598
Cell Significance Index: -3.1400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0606
Cell Significance Index: -1.9300 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0610
Cell Significance Index: -1.9300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0637
Cell Significance Index: -2.0900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0664
Cell Significance Index: -2.5200 - Cell Name: secretory cell (CL0000151)
Fold Change: -0.0764
Cell Significance Index: -0.5300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0777
Cell Significance Index: -1.5600 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.0824
Cell Significance Index: -1.3300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0851
Cell Significance Index: -2.2800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0859
Cell Significance Index: -2.4500 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: -0.0860
Cell Significance Index: -0.7400 - Cell Name: neuron (CL0000540)
Fold Change: -0.0865
Cell Significance Index: -0.8200 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0877
Cell Significance Index: -3.5900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0882
Cell Significance Index: -4.4600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0928
Cell Significance Index: -3.2600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0937
Cell Significance Index: -0.9700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0946
Cell Significance Index: -2.3600 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: -0.0957
Cell Significance Index: -1.0100 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.1031
Cell Significance Index: -1.4300 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1032
Cell Significance Index: -2.1000 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.1069
Cell Significance Index: -0.5600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1084
Cell Significance Index: -2.3000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1097
Cell Significance Index: -3.1600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1106
Cell Significance Index: -2.3900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1134
Cell Significance Index: -3.3400 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1158
Cell Significance Index: -2.5400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1183
Cell Significance Index: -3.1600 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -0.1230
Cell Significance Index: -0.8000 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1234
Cell Significance Index: -2.4400 - Cell Name: retinal astrocyte (CL4033015)
Fold Change: -0.1236
Cell Significance Index: -1.2100 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.1237
Cell Significance Index: -1.8500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1276
Cell Significance Index: -2.6700 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1280
Cell Significance Index: -3.2600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1291
Cell Significance Index: -2.5200 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1308
Cell Significance Index: -2.7300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1309
Cell Significance Index: -3.1400 - Cell Name: glioblast (CL0000030)
Fold Change: -0.1322
Cell Significance Index: -0.8300 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1333
Cell Significance Index: -3.3300 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.1346
Cell Significance Index: -2.6500 - Cell Name: lung resident memory CD8-positive, alpha-beta T cell (CL4033039)
Fold Change: -0.1356
Cell Significance Index: -1.2000 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.1384
Cell Significance Index: -2.7600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1385
Cell Significance Index: -2.9600 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.1388
Cell Significance Index: -1.8500 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: -0.1538
Cell Significance Index: -1.3900 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.1585
Cell Significance Index: -2.0300 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.1588
Cell Significance Index: -3.1100 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: -0.1588
Cell Significance Index: -1.6200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1596
Cell Significance Index: -3.3100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4152355152
Symbol: PAX7_HUMAN
Name: Paired box protein Pax-7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9339373
Title: The genomic organization and the full coding region of the human PAX7 gene.
PubMed ID: 9339373
PubMed ID: 16830101
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7527137
Title: Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes.
PubMed ID: 7527137
PubMed ID: 2501086
Title: Conservation of the paired domain in metazoans and its structure in three isolated human genes.
PubMed ID: 2501086
PubMed ID: 8187070
Title: Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma.
PubMed ID: 8187070
PubMed ID: 10393185
Title: The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx.
PubMed ID: 10393185
PubMed ID: 31092906
Title: Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy.
PubMed ID: 31092906
Sequence Information:
- Length: 505
- Mass: 55119
- Checksum: E51CF8B3E8D4C3D9
- Sequence:
MAALPGTVPR MMRPAPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPRQVA TPDVEKKIEE YKRENPGMFS WEIRDRLLKD GHCDRSTVPS GLVSSISRVL RIKFGKKEEE DEADKKEDDG EKKAKHSIDG ILGDKGNRLD EGSDVESEPD LPLKRKQRRS RTTFTAEQLE ELEKAFERTH YPDIYTREEL AQRTKLTEAR VQVWFSNRRA RWRKQAGANQ LAAFNHLLPG GFPPTGMPTL PPYQLPDSTY PTTTISQDGG STVHRPQPLP PSTMHQGGLA AAAAAADTSS AYGARHSFSS YSDSFMNPAA PSNHMNPVSN GLSPQVMSIL GNPSAVPPQP QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT GYSVDPVAGY QYGQYGQTAV DYLAKNVSLS TQRRMKLGEH SAVLGLLPVE TGQAY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.