Details for: SLC45A2

Gene ID: 51151

Symbol: SLC45A2

Ensembl ID: ENSG00000164175

Description: solute carrier family 45 member 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 16.5981
    Cell Significance Index: -4.2100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.2969
    Cell Significance Index: 79.5100
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.1652
    Cell Significance Index: 28.2300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.9043
    Cell Significance Index: 131.4500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4694
    Cell Significance Index: 89.3300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.4277
    Cell Significance Index: 6.1300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3443
    Cell Significance Index: 7.5400
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: 0.2704
    Cell Significance Index: 3.7900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.2604
    Cell Significance Index: 3.7800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2334
    Cell Significance Index: 14.0200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2219
    Cell Significance Index: 4.7300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.2096
    Cell Significance Index: 60.3200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2000
    Cell Significance Index: 19.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1886
    Cell Significance Index: 170.3000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1753
    Cell Significance Index: 19.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1590
    Cell Significance Index: 31.9100
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.1283
    Cell Significance Index: 1.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1262
    Cell Significance Index: 237.6700
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.1198
    Cell Significance Index: 0.2700
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.1175
    Cell Significance Index: 1.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1172
    Cell Significance Index: 23.2700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1105
    Cell Significance Index: 17.9800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0985
    Cell Significance Index: 35.3200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0744
    Cell Significance Index: 5.1500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0403
    Cell Significance Index: 1.1600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0383
    Cell Significance Index: 0.8000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0314
    Cell Significance Index: 21.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0290
    Cell Significance Index: 1.1000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0270
    Cell Significance Index: 0.9500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0210
    Cell Significance Index: 0.9500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0205
    Cell Significance Index: 0.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0111
    Cell Significance Index: 0.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0108
    Cell Significance Index: 0.2700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0091
    Cell Significance Index: 14.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0090
    Cell Significance Index: 12.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0022
    Cell Significance Index: 1.4200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0006
    Cell Significance Index: 1.0800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0002
    Cell Significance Index: 0.0100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0014
    Cell Significance Index: -0.0800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0030
    Cell Significance Index: -2.2100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0038
    Cell Significance Index: -0.1900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0046
    Cell Significance Index: -2.6000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0057
    Cell Significance Index: -0.0900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0059
    Cell Significance Index: -3.6600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0061
    Cell Significance Index: -2.7700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0064
    Cell Significance Index: -3.4800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0067
    Cell Significance Index: -0.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0076
    Cell Significance Index: -5.5600
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.0085
    Cell Significance Index: -0.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0091
    Cell Significance Index: -1.1700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0105
    Cell Significance Index: -0.8100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0106
    Cell Significance Index: -0.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0118
    Cell Significance Index: -0.5500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0125
    Cell Significance Index: -2.2600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0127
    Cell Significance Index: -0.2700
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.0128
    Cell Significance Index: -0.1200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0178
    Cell Significance Index: -0.7300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0179
    Cell Significance Index: -0.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0190
    Cell Significance Index: -1.2000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0194
    Cell Significance Index: -4.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0209
    Cell Significance Index: -3.5700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0241
    Cell Significance Index: -0.6000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0286
    Cell Significance Index: -3.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0286
    Cell Significance Index: -2.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0338
    Cell Significance Index: -4.1500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0340
    Cell Significance Index: -3.8900
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: -0.0386
    Cell Significance Index: -0.0500
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.0428
    Cell Significance Index: -0.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0434
    Cell Significance Index: -1.3900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0439
    Cell Significance Index: -5.1200
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0462
    Cell Significance Index: -0.4000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0466
    Cell Significance Index: -2.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0469
    Cell Significance Index: -4.8000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0471
    Cell Significance Index: -0.7100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0475
    Cell Significance Index: -0.4500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0578
    Cell Significance Index: -1.4100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0595
    Cell Significance Index: -1.5300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0605
    Cell Significance Index: -1.9800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0644
    Cell Significance Index: -2.0500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0654
    Cell Significance Index: -2.2900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0682
    Cell Significance Index: -3.5800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0694
    Cell Significance Index: -1.7300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0713
    Cell Significance Index: -1.4100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0739
    Cell Significance Index: -4.7700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0787
    Cell Significance Index: -1.7000
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0806
    Cell Significance Index: -0.6700
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.0874
    Cell Significance Index: -0.7900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0895
    Cell Significance Index: -1.7500
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0897
    Cell Significance Index: -1.2100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0913
    Cell Significance Index: -1.0400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0928
    Cell Significance Index: -1.3700
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0930
    Cell Significance Index: -1.5900
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.0936
    Cell Significance Index: -0.9800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0953
    Cell Significance Index: -1.9900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0959
    Cell Significance Index: -2.6100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0971
    Cell Significance Index: -1.6400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0976
    Cell Significance Index: -2.6200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1005
    Cell Significance Index: -4.7300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1006
    Cell Significance Index: -2.0200
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.1012
    Cell Significance Index: -1.3100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Gene structure and expression**: The SLC45A2 gene is located on chromosome 15q13.1 and consists of 14 exons. It is highly expressed in cells involved in melanin production, such as melanocytes, and is also found in other tissues, including the brain and immune cells. 2. **Protein function**: The SLC45A2 protein is a transmembrane protein that functions as a glucose-proton symporter, facilitating the transport of glucose across cell membranes. This function is essential for maintaining glucose homeostasis and regulating cellular metabolism. 3. **Cellular localization**: The SLC45A2 protein is primarily found in the plasma membrane of cells, where it can interact with other proteins and influence cellular signaling pathways. **Pathways and Functions:** 1. **Melanin biosynthesis**: SLC45A2 plays a critical role in regulating melanin production by transporting glucose and other solutes required for melanin synthesis. This process involves the conversion of tyrosine to melanin through a series of enzyme-catalyzed reactions. 2. **Developmental pigmentation**: The SLC45A2 gene is involved in the regulation of developmental pigmentation, including the formation of melanocytes and the distribution of melanin in the skin and hair. 3. **Lysosomal function**: SLC45A2 also plays a role in regulating lysosomal function, particularly in the context of melanin degradation and recycling. 4. **Cellular metabolism**: The SLC45A2 protein is involved in regulating cellular metabolism by facilitating the transport of glucose and other solutes across cell membranes. **Clinical Significance:** 1. **Melanoma and skin cancer**: Mutations in the SLC45A2 gene have been associated with an increased risk of melanoma and other skin cancers. This highlights the importance of SLC45A2 in regulating melanin production and preventing cancer. 2. **Albinism**: Individuals with albinism, a genetic disorder characterized by a lack of melanin production, often exhibit defects in SLC45A2 expression or function. 3. **Immune system disorders**: SLC45A2 is also expressed in immune cells, and alterations in its expression or function may contribute to immune system disorders, such as autoimmune diseases or immunodeficiency syndromes. 4. **Neurological disorders**: The SLC45A2 gene is also expressed in the brain, and dysregulation of its function may contribute to neurological disorders, such as Parkinson's disease or Alzheimer's disease. In conclusion, the SLC45A2 gene plays a critical role in regulating melanin biosynthesis, developmental pigmentation, and lysosomal function. Its dysregulation has been implicated in various diseases, including melanoma, albinism, and immune system disorders. Further research into the functions and clinical significance of the SLC45A2 gene is necessary to fully understand its importance in human health and disease.

Genular Protein ID: 380129960

Symbol: S45A2_HUMAN

Name: Melanoma antigen AIM1

UniProtKB Accession Codes:

Q9UMX9 Q6P2P0 Q9BTM3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 4 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 4 MalaCards 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 3 Rhea 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 11221837

Title: Use of an in vitro immunoselected tumor line to identify shared melanoma antigens recognized by HLA-A*0201-restricted T cells.

PubMed ID: 11221837

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 35469906

Title: Ablation of H+/glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis.

PubMed ID: 35469906

DOI: 10.1016/j.jid.2022.04.008

PubMed ID: 11574907

Title: Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4.

PubMed ID: 11574907

DOI: 10.1086/324340

PubMed ID: 14961451

Title: Oculocutaneous albinism type 4 is one of the most common types of albinism in Japan.

PubMed ID: 14961451

DOI: 10.1086/382195

PubMed ID: 14722913

Title: Mutations in the MATP gene in five German patients affected by oculocutaneous albinism type 4.

PubMed ID: 14722913

DOI: 10.1002/humu.10311

PubMed ID: 15455243

Title: MATP polymorphisms in Germans and Japanese: the L374F mutation as a population marker for Caucasoids.

PubMed ID: 15455243

DOI: 10.1007/s00414-004-0490-z

PubMed ID: 15656822

Title: A Korean case of oculocutaneous albinism type IV caused by a D157N mutation in the MATP gene.

PubMed ID: 15656822

DOI: 10.1111/j.1365-2133.2005.06403.x

PubMed ID: 15714523

Title: Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation.

PubMed ID: 15714523

DOI: 10.1002/humu.20143

PubMed ID: 17044855

Title: Distribution of the F374 allele of the SLC45A2 (MATP) gene and founder-haplotype analysis.

PubMed ID: 17044855

DOI: 10.1111/j.1469-1809.2006.00261.x

PubMed ID: 17999355

Title: A genomewide association study of skin pigmentation in a South Asian population.

PubMed ID: 17999355

DOI: 10.1086/522235

PubMed ID: 17768386

Title: SLC45A2 variations in Indian oculocutaneous albinism patients.

PubMed ID: 17768386

PubMed ID: 18683857

Title: Variants of the MATP/SLC45A2 gene are protective for melanoma in the French population.

PubMed ID: 18683857

DOI: 10.1002/humu.20823

PubMed ID: 18563784

Title: SLC45A2: a novel malignant melanoma-associated gene.

PubMed ID: 18563784

DOI: 10.1002/humu.20804

PubMed ID: 19865097

Title: A comprehensive analysis reveals mutational spectra and common alleles in Chinese patients with oculocutaneous albinism.

PubMed ID: 19865097

DOI: 10.1038/jid.2009.339

PubMed ID: 23504663

Title: DNA variations in oculocutaneous albinism: an updated mutation list and current outstanding issues in molecular diagnostics.

PubMed ID: 23504663

DOI: 10.1002/humu.22315

PubMed ID: 25703744

Title: Mutational spectrum of the TYR and SLC45A2 genes in Pakistani families with oculocutaneous albinism, and potential founder effect of missense substitution (p.Arg77Gln) of tyrosinase.

PubMed ID: 25703744

DOI: 10.1111/ced.12612

PubMed ID: 32966160

Title: SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation.

PubMed ID: 32966160

DOI: 10.1091/mbc.e20-03-0200

PubMed ID: 38337174

Title: Oculocutaneous albinism type 4: Novel compound heterozygous mutations in the SLC45A2 gene in a Chinese case.

PubMed ID: 38337174

DOI: 10.1002/mgg3.2385

Sequence Information:

  • Length: 530
  • Mass: 58268
  • Checksum: 11AA45A24EC1B35B
  • Sequence:
    • MGSNSGQAGR HIYKSLADDG PFDSVEPPKR PTSRLIMHSM AMFGREFCYA VEAAYVTPVL 
LSVGLPSSLY SIVWFLSPIL GFLLQPVVGS ASDHCRSRWG RRRPYILTLG VMMLVGMALY 
LNGATVVAAL IANPRRKLVW AISVTMIGVV LFDFAADFID GPIKAYLFDV CSHQDKEKGL 
HYHALFTGFG GALGYLLGAI DWAHLELGRL LGTEFQVMFF FSALVLTLCF TVHLCSISEA 
PLTEVAKGIP PQQTPQDPPL SSDGMYEYGS IEKVKNGYVN PELAMQGAKN KNHAEQTRRA 
MTLKSLLRAL VNMPPHYRYL CISHLIGWTA FLSNMLFFTD FMGQIVYRGD PYSAHNSTEF 
LIYERGVEVG CWGLCINSVF SSLYSYFQKV LVSYIGLKGL YFTGYLLFGL GTGFIGLFPN 
VYSTLVLCSL FGVMSSTLYT VPFNLITEYH REEEKERQQA PGGDPDNSVR GKGMDCATLT 
CMVQLAQILV GGGLGFLVNT AGTVVVVVIT ASAVALIGCC FVALFVRYVD

Genular Protein ID: 3464333502

Symbol: A0A076YGN1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A076YGN1

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 3 GO 2 Gene3D 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 25093503

Title: The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population.

PubMed ID: 25093503

Sequence Information:

  • Length: 530
  • Mass: 58302
  • Checksum: F14A4BACAA8FF31B
  • Sequence:
    • MGSNSGQAGR HIYKSLADDG PFDSVEPPKR PTSRLIMHSM AMFGREFCYA VEAAYVTPVL 
LSVGLPSSLY SIVWFLSPIL GFLLQPVVGS ASDHCRSRWG RRRPYILTLG VMMLVGMALY 
LNGATVVAAL IANPRRKLVW AISVTMIGVV LFDFAADFID GPIKAYLFDV CSHQDKEKGL 
HYHALFTGFG GALGYLLGAI DWAHLELGRL LGTEFQVMFF FSALVLTLCF TVHLCSISEA 
PLTEVAKGIP PQQTPQDPPL SSDGMYEYGS IEKVKNGYVN PELAMQGAKN KNHAEQTRRA 
MTLKSLLRAL VNMPPHYRYL CISHLIGWTA FLSNMLFFTD FMGQIVYRGD PYSAHNSTEF 
LIYERGVEVG CWGFCINSVF SSLYSYFQKV LVSYIGLKGL YFTGYLLFGL GTGFIGLFPN 
VYSTLVLCSL FGVMSSTLYT VPFNLITEYH REEEKERQQA PGGDPDNSVR GKGMDCATLT 
CMVQLAQILV GGGLGFLVNT AGTVVVVVIT ASAVALIGCC FVALFVRYVD

Genular Protein ID: 2360375105

Symbol: D6RGY6_HUMAN

Name: N/A

UniProtKB Accession Codes:

D6RGY6

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 243
  • Mass: 26710
  • Checksum: 296BE181FAC6ECA0
  • Sequence:
    • MGSNSGQAGR HIYKSLADDG PFDSVEPPKR PTSRLIMHSM AMFGREFCYA VEAAYVTPVL 
LSVGLPSSLY SIVWFLSPIL GFLLQPVVGS ASDHCRSRWG RRRPYILTLG VMMLVGMALY 
LNGATVVAAL IANPRRKLVW AISVTMIGVV LFDFAADFID GPIKAYLFDV CSHQDKEKGL 
HYHALFTDSQ GNDIKVTAES TGEHASSLPL PLHQPPHWMD SLPVQHAVLH RFHGPDCVPR 
GSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.