Details for: SERPINF2

Gene ID: 5345

Symbol: SERPINF2

Ensembl ID: ENSG00000167711

Description: serpin family F member 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 41.0813
    Cell Significance Index: -6.3900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 23.1427
    Cell Significance Index: -5.8700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 16.9801
    Cell Significance Index: 250.6300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 5.8905
    Cell Significance Index: 99.2300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.1827
    Cell Significance Index: -6.3900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 3.5714
    Cell Significance Index: 708.7500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.3227
    Cell Significance Index: 18.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.6371
    Cell Significance Index: -6.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.3523
    Cell Significance Index: 133.7800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.3139
    Cell Significance Index: 21.0800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.2771
    Cell Significance Index: -2.8000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.2119
    Cell Significance Index: 25.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.1564
    Cell Significance Index: 168.0900
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.1357
    Cell Significance Index: 6.5400
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.0627
    Cell Significance Index: 4.5700
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.8427
    Cell Significance Index: 7.4800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7642
    Cell Significance Index: 83.1200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7063
    Cell Significance Index: 114.8700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6216
    Cell Significance Index: 37.3200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.5514
    Cell Significance Index: 16.2400
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 0.4806
    Cell Significance Index: 1.8100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.4457
    Cell Significance Index: 3.0200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3583
    Cell Significance Index: 9.5900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.2009
    Cell Significance Index: 152.1000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.1554
    Cell Significance Index: 2.3600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1247
    Cell Significance Index: 3.4000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1151
    Cell Significance Index: 1.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0975
    Cell Significance Index: 43.0900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0809
    Cell Significance Index: 15.3900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0784
    Cell Significance Index: 15.7200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0410
    Cell Significance Index: 28.3300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0181
    Cell Significance Index: 6.4800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0157
    Cell Significance Index: 0.4000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0143
    Cell Significance Index: 0.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0119
    Cell Significance Index: 22.3900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0106
    Cell Significance Index: 1.4600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0100
    Cell Significance Index: 0.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0056
    Cell Significance Index: 0.1600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0028
    Cell Significance Index: 1.5400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0022
    Cell Significance Index: -4.1100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0031
    Cell Significance Index: -0.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0034
    Cell Significance Index: -5.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0040
    Cell Significance Index: -2.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0050
    Cell Significance Index: -6.7700
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0052
    Cell Significance Index: -0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0052
    Cell Significance Index: -3.8900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0056
    Cell Significance Index: -1.6200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0057
    Cell Significance Index: -1.0300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0064
    Cell Significance Index: -0.1800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0073
    Cell Significance Index: -0.1100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0085
    Cell Significance Index: -0.3000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0086
    Cell Significance Index: -4.8400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0095
    Cell Significance Index: -6.9600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0099
    Cell Significance Index: -6.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0101
    Cell Significance Index: -0.4700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0103
    Cell Significance Index: -0.5200
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.0111
    Cell Significance Index: -0.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0115
    Cell Significance Index: -5.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0193
    Cell Significance Index: -2.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0196
    Cell Significance Index: -1.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0224
    Cell Significance Index: -2.2900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0249
    Cell Significance Index: -3.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0272
    Cell Significance Index: -3.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0279
    Cell Significance Index: -1.3100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0348
    Cell Significance Index: -7.3300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0352
    Cell Significance Index: -0.6000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0360
    Cell Significance Index: -4.2000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0394
    Cell Significance Index: -1.0600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0414
    Cell Significance Index: -0.6200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0445
    Cell Significance Index: -3.1500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0448
    Cell Significance Index: -2.0300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0499
    Cell Significance Index: -1.2500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0501
    Cell Significance Index: -1.0400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0558
    Cell Significance Index: -5.8100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0647
    Cell Significance Index: -7.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0663
    Cell Significance Index: -2.1100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0677
    Cell Significance Index: -7.7600
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.0721
    Cell Significance Index: -0.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0740
    Cell Significance Index: -2.3700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0746
    Cell Significance Index: -3.2400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0773
    Cell Significance Index: -4.7400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0783
    Cell Significance Index: -0.8900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0816
    Cell Significance Index: -2.6700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0846
    Cell Significance Index: -6.4900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0855
    Cell Significance Index: -0.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0893
    Cell Significance Index: -7.0700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0899
    Cell Significance Index: -3.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0989
    Cell Significance Index: -5.1400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1004
    Cell Significance Index: -4.4400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1026
    Cell Significance Index: -4.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1056
    Cell Significance Index: -6.8200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1066
    Cell Significance Index: -5.9800
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1128
    Cell Significance Index: -1.5700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1171
    Cell Significance Index: -6.1500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1175
    Cell Significance Index: -3.0200
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.1191
    Cell Significance Index: -0.9400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1221
    Cell Significance Index: -3.0500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1223
    Cell Significance Index: -4.6300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1242
    Cell Significance Index: -6.4700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1259
    Cell Significance Index: -2.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** SERPINF2 is a serine protease inhibitor (serpin) that consists of a single-chain molecule with a characteristic serpin fold. 2. **Function:** SERPINF2 inhibits a range of proteases, including plasminogen activators, thrombin, and trypsin, thereby regulating fibrinolysis, hemostasis, and cell differentiation. 3. **Expression:** SERPINF2 is widely expressed in various cell types, including hepatocytes, endothelial cells, pneumocytes, and retinal cells. 4. **Regulation:** SERPINF2 is regulated by various factors, including platelet-derived growth factors, transforming growth factor-beta, and the renin-angiotensin system. **Pathways and Functions:** 1. **Hemostasis:** SERPINF2 regulates fibrinolysis by inhibiting plasminogen activators, thereby maintaining blood clot stability. 2. **Fibrinolysis:** SERPINF2 inhibits plasminogen activators, which are responsible for dissolving fibrin clots. 3. **Cell Differentiation:** SERPINF2 regulates cell differentiation by inhibiting proteases that are involved in cell signaling pathways. 4. **Cell Adhesion:** SERPINF2 promotes cell adhesion by regulating cadherin-mediated adhesion. 5. **Smooth Muscle Cell Proliferation:** SERPINF2 regulates smooth muscle cell proliferation by inhibiting proteases that are involved in cell signaling pathways. 6. **Stress Fiber Assembly:** SERPINF2 regulates stress fiber assembly by inhibiting proteases that are involved in cell signaling pathways. **Clinical Significance:** 1. **Thrombosis and Hemorrhage:** SERPINF2 deficiency or dysfunction has been associated with thrombosis and hemorrhage, highlighting its importance in maintaining hemostasis. 2. **Cancer:** SERPINF2 has been implicated in cancer progression, particularly in lung and breast cancer, where it regulates cell differentiation and proliferation. 3. **Cardiovascular Disease:** SERPINF2 has been linked to cardiovascular disease, particularly in cases of hypertension and atherosclerosis, where it regulates smooth muscle cell proliferation and angiogenesis. 4. **Neurological Disorders:** SERPINF2 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it regulates cell differentiation and aggregation. In conclusion, SERPINF2 is a multifunctional gene that plays a critical role in regulating hemostasis, fibrinolysis, and cell differentiation. Its dysregulation has been implicated in various diseases, including thrombosis, cancer, cardiovascular disease, and neurological disorders. Further research is needed to fully understand the mechanisms by which SERPINF2 regulates these processes and to develop therapeutic strategies for its dysregulation.

Genular Protein ID: 2835059777

Symbol: A2AP_HUMAN

Name: Alpha-2-antiplasmin

UniProtKB Accession Codes:

P08697 B4E1B7 Q8N5U7 Q9UCG2 Q9UCG3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 11 Ensembl 6 ExpressionAtlas 1 GO 28 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2830248

Title: Structure of human alpha 2-plasmin inhibitor deduced from the cDNA sequence.

PubMed ID: 2830248

DOI: 10.1093/oxfordjournals.jbchem.a122141

PubMed ID: 3166140

Title: Organization of the human alpha 2-plasmin inhibitor gene.

PubMed ID: 3166140

DOI: 10.1073/pnas.85.18.6836

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2433286

Title: Primary structure of human alpha 2-antiplasmin, a serine protease inhibitor (serpin).

PubMed ID: 2433286

DOI: 10.1016/s0021-9258(19)75687-7

PubMed ID: 8484741

Title: Different N-terminal forms of alpha 2-plasmin inhibitor in human plasma.

PubMed ID: 8484741

DOI: 10.1042/bj2910623

PubMed ID: 1385210

Title: Bovine alpha 2-antiplasmin. N-terminal and reactive site sequence.

PubMed ID: 1385210

DOI: 10.1016/0014-5793(92)81419-m

PubMed ID: 2440681

Title: Amino-acid sequence of human alpha 2-antiplasmin.

PubMed ID: 2440681

DOI: 10.1111/j.1432-1033.1987.tb13551.x

PubMed ID: 21075

Title: Purification and characterization of human antiplasmin, the fast-acting plasmin inhibitor in plasma.

PubMed ID: 21075

DOI: 10.1111/j.1432-1033.1977.tb11709.x

PubMed ID: 3818581

Title: Structure of the carboxyl-terminal half of human alpha 2-plasmin inhibitor deduced from that of cDNA.

PubMed ID: 3818581

DOI: 10.1093/oxfordjournals.jbchem.a121846

PubMed ID: 2434496

Title: Sulfation of a tyrosine residue in the plasmin-binding domain of alpha 2-antiplasmin.

PubMed ID: 2434496

DOI: 10.1016/s0021-9258(18)61471-1

PubMed ID: 2456616

Title: Alpha-2-antiplasmin: a serpin with two separate but overlapping reactive sites.

PubMed ID: 2456616

DOI: 10.1126/science.2456616

PubMed ID: 9169621

Title: Assignment of a single disulphide bridge in human alpha2-antiplasmin: implications for the structural and functional properties.

PubMed ID: 9169621

DOI: 10.1042/bj3230847

PubMed ID: 14751930

Title: A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion.

PubMed ID: 14751930

DOI: 10.1182/blood-2003-12-4240

PubMed ID: 15853774

Title: Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.

PubMed ID: 15853774

DOI: 10.1042/bj20050299

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16223769

Title: Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein.

PubMed ID: 16223769

DOI: 10.1182/blood-2005-08-3452

PubMed ID: 2572590

Title: Hereditary alpha 2-plasmin inhibitor deficiency caused by a transport-deficient mutation (alpha 2-PI-Okinawa). Deletion of Glu137 by a trinucleotide deletion blocks intracellular transport.

PubMed ID: 2572590

DOI: 10.1016/s0021-9258(19)84699-9

PubMed ID: 10583218

Title: A novel missense mutation in the human plasmin inhibitor (alpha2-antiplasmin) gene associated with a bleeding tendency.

PubMed ID: 10583218

DOI: 10.1046/j.1365-2141.1999.01708.x

Sequence Information:

  • Length: 491
  • Mass: 54566
  • Checksum: 385A1C90E91A63CB
  • Sequence:
    • MALLWGLLVL SWSCLQGPCS VFSPVSAMEP LGRQLTSGPN QEQVSPLTLL KLGNQEPGGQ 
TALKSPPGVC SRDPTPEQTH RLARAMMAFT ADLFSLVAQT STCPNLILSP LSVALALSHL 
ALGAQNHTLQ RLQQVLHAGS GPCLPHLLSR LCQDLGPGAF RLAARMYLQK GFPIKEDFLE 
QSEQLFGAKP VSLTGKQEDD LANINQWVKE ATEGKIQEFL SGLPEDTVLL LLNAIHFQGF 
WRNKFDPSLT QRDSFHLDEQ FTVPVEMMQA RTYPLRWFLL EQPEIQVAHF PFKNNMSFVV 
LVPTHFEWNV SQVLANLSWD TLHPPLVWER PTKVRLPKLY LKHQMDLVAT LSQLGLQELF 
QAPDLRGISE QSLVVSGVQH QSTLELSEVG VEAAAATSIA MSRMSLSSFS VNRPFLFFIF 
EDTTGLPLFV GSVRNPNPSA PRELKEQQDS PGNKDFLQSL KGFPRGDKLF GPDLKLVPPM 
EEDYPQFGSP K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.