Details for: RGS7

Gene ID: 6000

Symbol: RGS7

Ensembl ID: ENSG00000182901

Description: regulator of G protein signaling 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.3289
    Cell Significance Index: -31.3600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 6.8451
    Cell Significance Index: 117.3100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 6.7842
    Cell Significance Index: 193.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 6.6775
    Cell Significance Index: 295.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 6.3656
    Cell Significance Index: 241.0500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 5.5044
    Cell Significance Index: 370.1200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 5.2553
    Cell Significance Index: 1884.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.6924
    Cell Significance Index: 740.7000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.2932
    Cell Significance Index: 2277.7300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 3.1096
    Cell Significance Index: 190.6500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 2.9086
    Cell Significance Index: 37.7200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.6417
    Cell Significance Index: 162.3700
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 2.0210
    Cell Significance Index: 28.2600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 2.0112
    Cell Significance Index: 20.9500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.8171
    Cell Significance Index: 44.0200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.3226
    Cell Significance Index: 31.7200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.2824
    Cell Significance Index: 28.0800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.2348
    Cell Significance Index: 69.2900
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.8070
    Cell Significance Index: 6.1900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4962
    Cell Significance Index: 448.0000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0957
    Cell Significance Index: 5.0300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0443
    Cell Significance Index: 4.3800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0087
    Cell Significance Index: 0.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0057
    Cell Significance Index: 10.7800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0009
    Cell Significance Index: -0.0100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0052
    Cell Significance Index: -0.9900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0231
    Cell Significance Index: -42.5800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0330
    Cell Significance Index: -50.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0525
    Cell Significance Index: -71.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0776
    Cell Significance Index: -57.4600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0825
    Cell Significance Index: -13.4200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1257
    Cell Significance Index: -92.1500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1295
    Cell Significance Index: -82.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1298
    Cell Significance Index: -98.2200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1371
    Cell Significance Index: -77.3000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1451
    Cell Significance Index: -4.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1606
    Cell Significance Index: -100.2600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1653
    Cell Significance Index: -90.3000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1781
    Cell Significance Index: -80.8200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2221
    Cell Significance Index: -2.7700
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.2596
    Cell Significance Index: -2.4700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2675
    Cell Significance Index: -76.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.3027
    Cell Significance Index: -60.0800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3052
    Cell Significance Index: -4.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3144
    Cell Significance Index: -7.8600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.3253
    Cell Significance Index: -4.3400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3722
    Cell Significance Index: -7.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.4096
    Cell Significance Index: -73.8400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4230
    Cell Significance Index: -8.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4265
    Cell Significance Index: -89.8300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4488
    Cell Significance Index: -9.0100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.4521
    Cell Significance Index: -49.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.5024
    Cell Significance Index: -85.7800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5232
    Cell Significance Index: -76.0600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.5428
    Cell Significance Index: -24.6100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5458
    Cell Significance Index: -17.8700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.5887
    Cell Significance Index: -80.8500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6399
    Cell Significance Index: -20.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.6436
    Cell Significance Index: -79.1400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.7582
    Cell Significance Index: -9.5700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.7791
    Cell Significance Index: -90.8000
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.8242
    Cell Significance Index: -9.6200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8281
    Cell Significance Index: -94.8700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8303
    Cell Significance Index: -86.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.8533
    Cell Significance Index: -100.6300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.8997
    Cell Significance Index: -91.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.9496
    Cell Significance Index: -65.6700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.0477
    Cell Significance Index: -29.2800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.0965
    Cell Significance Index: -84.1400
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.1720
    Cell Significance Index: -11.1100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.1816
    Cell Significance Index: -93.5900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.1937
    Cell Significance Index: -25.7900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.2188
    Cell Significance Index: -73.1700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.2719
    Cell Significance Index: -15.2100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.5663
    Cell Significance Index: -39.0700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.5982
    Cell Significance Index: -100.7300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.6067
    Cell Significance Index: -20.2800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.6120
    Cell Significance Index: -56.4700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.6682
    Cell Significance Index: -53.4300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.7646
    Cell Significance Index: -38.2300
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -1.9723
    Cell Significance Index: -17.0600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.0045
    Cell Significance Index: -94.2100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.0480
    Cell Significance Index: -35.4100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -2.0488
    Cell Significance Index: -42.7600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -2.1390
    Cell Significance Index: -23.6000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.1785
    Cell Significance Index: -113.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -2.2829
    Cell Significance Index: -106.4400
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -2.3897
    Cell Significance Index: -36.3600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -2.6541
    Cell Significance Index: -92.2300
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -2.7117
    Cell Significance Index: -31.0400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -2.8865
    Cell Significance Index: -75.9000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -2.9250
    Cell Significance Index: -36.2800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -2.9509
    Cell Significance Index: -58.0800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -2.9758
    Cell Significance Index: -59.3400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -3.0078
    Cell Significance Index: -95.1300
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -3.0243
    Cell Significance Index: -36.6600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -3.0255
    Cell Significance Index: -40.3300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -3.1551
    Cell Significance Index: -81.1000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -3.1794
    Cell Significance Index: -67.9600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -3.2555
    Cell Significance Index: -81.3100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Negative Regulation of GPCR Signaling:** RGS7 acts as a negative regulator of GPCR signaling by accelerating the GTPase activity of Gα subunits, thereby terminating the signaling cascade. 2. **Cellular Expression:** RGS7 is expressed in a wide range of cell types, including neuronal, epithelial, and immune cells, suggesting its involvement in various physiological processes. 3. **Molecular Mechanisms:** RGS7 interacts with Gα subunits, accelerating their GTPase activity and terminating the signaling cascade. 4. **Regulation of Protein Folding:** RGS7 has been implicated in the regulation of protein folding, particularly in the context of G-protein β-subunit folding. **Pathways and Functions:** 1. **G-Protein Coupled Receptor Signaling Pathway:** RGS7 regulates the activity of G-proteins, including Gαi, which is associated with inhibitory signaling. 2. **Cooperation of pdcl (phlp1) and tric/cct in G-Protein β Folding:** RGS7 interacts with pdcl (phlp1) and tric/cct, which are involved in the folding of G-protein β-subunits. 3. **Intracellular Signal Transduction:** RGS7 plays a role in regulating intracellular signal transduction pathways, including those involved in metabolism, potassium ion transport, and response to amphetamine and ethanol. 4. **G-Protein α-Subunit Binding:** RGS7 binds to Gα subunits, accelerating their GTPase activity and terminating the signaling cascade. **Clinical Significance:** 1. **Neurological Disorders:** RGS7 has been implicated in various neurological disorders, including Parkinson's disease, Alzheimer's disease, and schizophrenia, where dysregulation of G-protein signaling has been observed. 2. **Cancer:** RGS7 has been found to be overexpressed in certain types of cancer, including breast cancer and lung cancer, suggesting its potential role in oncogenesis. 3. **Immune System:** RGS7 has been implicated in the regulation of immune responses, particularly in the context of G-protein coupled receptor signaling in immune cells. 4. **Therapeutic Potential:** Targeting RGS7 may provide a new therapeutic strategy for treating various diseases, including neurological disorders and cancer, where dysregulation of G-protein signaling has been observed. In conclusion, RGS7 plays a crucial role in regulating G-protein coupled receptor signaling pathways, protein folding, and intracellular signal transduction. Its dysregulation has been implicated in various diseases, including neurological disorders, cancer, and immune system dysregulation. Further research is needed to fully elucidate the molecular mechanisms underlying RGS7's function and its potential therapeutic applications.

Genular Protein ID: 4190433387

Symbol: RGS7_HUMAN

Name: Regulator of G-protein signaling 7

UniProtKB Accession Codes:

P49802 Q5T3H4 Q8TD66 Q8TD67 Q8WW09 Q9UNU7 Q9Y6B9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 3 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EMDB 3 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10339594

Title: Interaction between RGS7 and polycystin.

PubMed ID: 10339594

DOI: 10.1073/pnas.96.11.6371

PubMed ID: 8548815

Title: EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.

PubMed ID: 8548815

DOI: 10.1016/s0092-8674(00)80998-8

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10521509

Title: Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways.

PubMed ID: 10521509

DOI: 10.1074/jbc.274.43.31087

PubMed ID: 10339615

Title: Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.

PubMed ID: 10339615

DOI: 10.1073/pnas.96.11.6489

PubMed ID: 10862767

Title: 14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity.

PubMed ID: 10862767

DOI: 10.1074/jbc.m002905200

PubMed ID: 12659861

Title: Snapin interacts with the N-terminus of regulator of G protein signaling 7.

PubMed ID: 12659861

DOI: 10.1016/s0006-291x(03)00400-5

PubMed ID: 15897264

Title: Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.

PubMed ID: 15897264

DOI: 10.1083/jcb.200502007

PubMed ID: 31189666

Title: Nonclassical ligand-independent regulation of Go protein by an orphan class C G-protein-coupled receptor.

PubMed ID: 31189666

DOI: 10.1124/mol.118.113019

PubMed ID: 18434541

Title: Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.

PubMed ID: 18434541

DOI: 10.1073/pnas.0801508105

PubMed ID: 34815401

Title: Structure of the class C orphan GPCR GPR158 in complex with RGS7-Gbeta5.

PubMed ID: 34815401

DOI: 10.1038/s41467-021-27147-1

PubMed ID: 34793198

Title: Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gbeta5 signaling complex.

PubMed ID: 34793198

DOI: 10.1126/science.abl4732

Sequence Information:

  • Length: 495
  • Mass: 57668
  • Checksum: 1FCC2D60622675DE
  • Sequence:
    • MAQGNNYGQT SNGVADESPN MLVYRKMEDV IARMQDEKNG IPIRTVKSFL SKIPSVFSGS 
DIVQWLIKNL TIEDPVEALH LGTLMAAHGY FFPISDHVLT LKDDGTFYRF QTPYFWPSNC 
WEPENTDYAV YLCKRTMQNK ARLELADYEA ESLARLQRAF ARKWEFIFMQ AEAQAKVDKK 
RDKIERKILD SQERAFWDVH RPVPGCVNTT EVDIKKSSRM RNPHKTRKSV YGLQNDIRSH 
SPTHTPTPET KPPTEDELQQ QIKYWQIQLD RHRLKMSKVA DSLLSYTEQY LEYDPFLLPP 
DPSNPWLSDD TTFWELEASK EPSQQRVKRW GFGMDEALKD PVGREQFLKF LESEFSSENL 
RFWLAVEDLK KRPIKEVPSR VQEIWQEFLA PGAPSAINLD SKSYDKTTQN VKEPGRYTFE 
DAQEHIYKLM KSDSYPRFIR SSAYQELLQA KKKSGNSMDR RTSFEKFAQN VGRNIPIFPC 
HKNCTPTLRA STNLL

Genular Protein ID: 2667237464

Symbol: A0A8I5KXW5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8I5KXW5

Database IDs:

ARBA 1 CDD 3 CTD 1 DisGeNET 1 EMBL 6 Ensembl 5 GO 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 11 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 3 SAM 1 SMART 4 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 443
  • Mass: 51858
  • Checksum: 4B007801E91D3694
  • Sequence:
    • MEDVIARMQD EKNGIPIRTV KSFLSKIPSV FSGSDIVQWL IKNLTIEDPV EALHLGTLMA 
AHGYFFPISD HVLTLKDDGT FYRFQTPYFW PSNCWEPENT DYAVYLCKRT MQNKARLELA 
DYEAESLARL QRAFARKWEF IFMQAEAQAK VDKKRDKIER KILDSQERAF WDVHRPVPGC 
VNTTEVDIKK SSRMRNPHKT RKSVYGLQND IRSHSPTHTP TPETKPPTED ELQQQIKYWQ 
IQLDRHRLKM SKVADSLLSY TEQYLEYDPF LLPPDPSNPW LSDDTTFWEL EASKEPSQQR 
VKRWGFGMDE ALKDPVGREQ FLKFLESEFS SENLRFWLAV EDLKKRPIKE VPSRVQEIWQ 
EFLAPGAPSA INLDSKSYDK TTQNVKEPGR YTFEDAQEHI YKLMKSDSYP RFIRSSAYQE 
LLQAKKKGKS LTSKRLTSLA QSY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.