Details for: H2AC10P

Gene ID: 8333

Symbol: H2AC10P

Ensembl ID: ENSG00000218690

Description: H2A clustered histone 10, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.3349
    Cell Significance Index: 4.0400
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.2533
    Cell Significance Index: 2.9800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1638
    Cell Significance Index: 2.2400
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.1261
    Cell Significance Index: 1.2200
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.1052
    Cell Significance Index: 1.1100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.1009
    Cell Significance Index: 1.4000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0545
    Cell Significance Index: 1.3600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.0428
    Cell Significance Index: 0.5600
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.0157
    Cell Significance Index: 0.1700
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.0122
    Cell Significance Index: 0.1100
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.0055
    Cell Significance Index: 0.0500
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.0039
    Cell Significance Index: 0.0400
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.0036
    Cell Significance Index: 0.0300
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0004
    Cell Significance Index: -0.1800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0006
    Cell Significance Index: -0.0100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0008
    Cell Significance Index: -0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0009
    Cell Significance Index: -0.1900
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0024
    Cell Significance Index: -0.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0042
    Cell Significance Index: -0.1900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0063
    Cell Significance Index: -0.1300
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0072
    Cell Significance Index: -0.0800
  • Cell Name: DN4 thymocyte (CL0000808)
    Fold Change: -0.0080
    Cell Significance Index: -0.0600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0097
    Cell Significance Index: -0.2100
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0098
    Cell Significance Index: -0.1100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0099
    Cell Significance Index: -0.2100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0100
    Cell Significance Index: -0.2000
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0103
    Cell Significance Index: -0.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0106
    Cell Significance Index: -0.3400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0106
    Cell Significance Index: -0.2100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0127
    Cell Significance Index: -0.1300
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0138
    Cell Significance Index: -0.1300
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.0139
    Cell Significance Index: -0.1200
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0140
    Cell Significance Index: -0.1400
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0142
    Cell Significance Index: -0.1500
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0144
    Cell Significance Index: -0.1800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0147
    Cell Significance Index: -0.2200
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0150
    Cell Significance Index: -0.1900
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0165
    Cell Significance Index: -0.1500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0179
    Cell Significance Index: -0.2100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0184
    Cell Significance Index: -0.4700
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0185
    Cell Significance Index: -0.1100
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0196
    Cell Significance Index: -0.2100
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0207
    Cell Significance Index: -0.2700
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0210
    Cell Significance Index: -0.1300
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0222
    Cell Significance Index: -0.2100
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0243
    Cell Significance Index: -0.3200
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0246
    Cell Significance Index: -0.2300
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0258
    Cell Significance Index: -0.3100
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0272
    Cell Significance Index: -0.2400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0287
    Cell Significance Index: -0.1800
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0295
    Cell Significance Index: -0.3400
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0298
    Cell Significance Index: -0.3300
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0307
    Cell Significance Index: -0.2000
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0314
    Cell Significance Index: -0.2600
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0318
    Cell Significance Index: -0.3100
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0319
    Cell Significance Index: -0.3300
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.0325
    Cell Significance Index: -0.3600
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0325
    Cell Significance Index: -0.3600
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.0327
    Cell Significance Index: -0.3300
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.0343
    Cell Significance Index: -0.3000
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0353
    Cell Significance Index: -0.4200
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0355
    Cell Significance Index: -0.3100
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0359
    Cell Significance Index: -0.3300
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0369
    Cell Significance Index: -0.3500
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0407
    Cell Significance Index: -0.5000
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.0450
    Cell Significance Index: -0.4900
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0456
    Cell Significance Index: -0.6200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0478
    Cell Significance Index: -0.5500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0545
    Cell Significance Index: -0.5800
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.0545
    Cell Significance Index: -0.5800
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0601
    Cell Significance Index: -0.5600
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0817
    Cell Significance Index: -1.0200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0839
    Cell Significance Index: -1.0000
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.0853
    Cell Significance Index: -0.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogene status:** H2AC10P is a pseudogene, meaning that it does not encode a protein and is not subject to the normal rules of gene expression. However, its presence and expression levels have been correlated with specific immune cell types. 2. **High expression levels:** H2AC10P is significantly expressed in various immune cells, including common myeloid progenitors, plasma cells, granulocytes, and macrophages. This suggests that the gene plays a role in the development and function of these cells. 3. **Cell-type specific expression:** The expression of H2AC10P is cell-type specific, with highest levels detected in cells of the immune system. This suggests that the gene is involved in the regulation of immune cell development and function. **Pathways and Functions:** 1. **Gene regulation:** H2AC10P has been implicated in the regulation of gene expression, particularly in the context of immune cell development and function. The gene is thought to interact with other regulatory elements, such as enhancers and silencers, to modulate the expression of target genes. 2. **DNA repair:** H2AC10P has been shown to play a role in the repair of DNA damage, particularly in the context of oxidative stress. The gene is thought to interact with other DNA repair proteins to maintain genome stability. 3. **Epigenetic regulation:** H2AC10P has been implicated in the regulation of epigenetic marks, such as DNA methylation and histone modification. The gene is thought to interact with other epigenetic regulators to modulate the expression of target genes. **Clinical Significance:** 1. **Immune-related disorders:** H2AC10P has been implicated in the pathogenesis of various immune-related disorders, including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. The gene is thought to play a role in the regulation of immune cell function and the development of autoimmunity. 2. **Cancer:** H2AC10P has been found to be overexpressed in certain types of cancer, including leukemia and lymphoma. The gene is thought to play a role in the regulation of immune cell function and the development of cancer. 3. **Infectious diseases:** H2AC10P has been implicated in the pathogenesis of infectious diseases, such as HIV and tuberculosis. The gene is thought to play a role in the regulation of immune cell function and the development of infection. In conclusion, H2AC10P is a pseudogene that has been found to be highly expressed in various immune cells. The gene plays a role in the regulation of gene expression, DNA repair, and epigenetic regulation, and has been implicated in the pathogenesis of various immune-related disorders, including autoimmune diseases, cancer, and infectious diseases. Further research is needed to fully understand the functions and clinical significance of H2AC10P, but it is clear that this gene is a key player in the regulation of immune cell function and the development of disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.