Details for: SEMA7A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 41.6599
Cell Significance Index: -6.4800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 32.0529
Cell Significance Index: -8.1300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 18.2889
Cell Significance Index: -7.4300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 7.7822
Cell Significance Index: -7.4300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 6.0018
Cell Significance Index: -7.4000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.2850
Cell Significance Index: -8.8000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.9366
Cell Significance Index: 152.5500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.5822
Cell Significance Index: 69.1900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.4716
Cell Significance Index: 155.7800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.0831
Cell Significance Index: -8.2200 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 2.0026
Cell Significance Index: 28.0900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.5759
Cell Significance Index: 299.9100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.5637
Cell Significance Index: 18.6400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.0629
Cell Significance Index: 105.1400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 1.0501
Cell Significance Index: 15.8300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.9964
Cell Significance Index: 26.2000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9811
Cell Significance Index: 885.8800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.8992
Cell Significance Index: 28.8000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.8756
Cell Significance Index: 23.3800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5347
Cell Significance Index: 86.9600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4755
Cell Significance Index: 51.7200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4520
Cell Significance Index: 90.6700 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.4120
Cell Significance Index: 2.5600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.3821
Cell Significance Index: 10.2200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2888
Cell Significance Index: 19.9800 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2868
Cell Significance Index: 6.2800 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 0.2789
Cell Significance Index: 3.7200 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.2606
Cell Significance Index: 1.3000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2055
Cell Significance Index: 24.2400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1671
Cell Significance Index: 10.0300 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.1369
Cell Significance Index: 1.9000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1255
Cell Significance Index: 2.7200 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.1070
Cell Significance Index: 1.1800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1062
Cell Significance Index: 3.0600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0990
Cell Significance Index: 68.4400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0938
Cell Significance Index: 18.6100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0749
Cell Significance Index: 8.7300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0552
Cell Significance Index: 1.9400 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0425
Cell Significance Index: 1.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0377
Cell Significance Index: 13.5100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.0331
Cell Significance Index: 0.3100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0295
Cell Significance Index: 16.1300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0015
Cell Significance Index: 2.0800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0028
Cell Significance Index: -0.0700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0029
Cell Significance Index: -0.3600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0034
Cell Significance Index: -6.4300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0035
Cell Significance Index: -5.4100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0039
Cell Significance Index: -7.1400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0069
Cell Significance Index: -1.2400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0099
Cell Significance Index: -0.4500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0106
Cell Significance Index: -8.0600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0108
Cell Significance Index: -7.9400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0108
Cell Significance Index: -0.5500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0116
Cell Significance Index: -8.6200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0119
Cell Significance Index: -7.5800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0128
Cell Significance Index: -1.6600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0146
Cell Significance Index: -6.4700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0154
Cell Significance Index: -8.6700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0170
Cell Significance Index: -7.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0189
Cell Significance Index: -2.6000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0206
Cell Significance Index: -5.9300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0241
Cell Significance Index: -0.9900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0259
Cell Significance Index: -4.4200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0347
Cell Significance Index: -1.6200 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.0368
Cell Significance Index: -0.3500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0378
Cell Significance Index: -1.9700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0395
Cell Significance Index: -8.3100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0433
Cell Significance Index: -6.2900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0441
Cell Significance Index: -0.7600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0511
Cell Significance Index: -2.4000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.0530
Cell Significance Index: -0.3200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0536
Cell Significance Index: -6.8700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0565
Cell Significance Index: -1.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0603
Cell Significance Index: -6.1600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0627
Cell Significance Index: -7.1800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0649
Cell Significance Index: -0.9300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0763
Cell Significance Index: -7.9500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0782
Cell Significance Index: -2.5600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0794
Cell Significance Index: -2.2200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0889
Cell Significance Index: -6.8200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0919
Cell Significance Index: -1.9500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0986
Cell Significance Index: -2.1000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1023
Cell Significance Index: -5.3700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1034
Cell Significance Index: -6.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1054
Cell Significance Index: -6.4600 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.1066
Cell Significance Index: -0.8800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1121
Cell Significance Index: -6.2900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1151
Cell Significance Index: -8.5800 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1166
Cell Significance Index: -1.2700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1182
Cell Significance Index: -4.1400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1213
Cell Significance Index: -2.0300 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1240
Cell Significance Index: -2.6800 - Cell Name: trophoblast giant cell (CL0002488)
Fold Change: -0.1249
Cell Significance Index: -0.9000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1456
Cell Significance Index: -6.4400 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1571
Cell Significance Index: -2.4300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1577
Cell Significance Index: -5.7900 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.1582
Cell Significance Index: -1.2900 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.1658
Cell Significance Index: -2.4800 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1672
Cell Significance Index: -3.4900 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1672
Cell Significance Index: -4.1700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 179999846
Symbol: SEM7A_HUMAN
Name: Semaphorin-7A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9721204
Title: New eukaryotic semaphorins with close homology to semaphorins of DNA viruses.
PubMed ID: 9721204
PubMed ID: 10201933
Title: Molecular cloning of a glycosylphosphatidylinositol-anchored molecule CDw108.
PubMed ID: 10201933
PubMed ID: 9712866
Title: Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins.
PubMed ID: 9712866
PubMed ID: 17207242
Title: The molecular diversity of Sema7A, the semaphorin that carries the JMH blood group antigens.
PubMed ID: 17207242
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10416131
Title: Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules.
PubMed ID: 10416131
PubMed ID: 12879062
Title: Semaphorin 7A promotes axon outgrowth through integrins and MAPKs.
PubMed ID: 12879062
DOI: 10.1038/nature01790
PubMed ID: 17377534
Title: Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.
PubMed ID: 17377534
DOI: 10.1038/nature05652
PubMed ID: 17671519
Title: Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins.
PubMed ID: 17671519
PubMed ID: 20727575
Title: Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1.
PubMed ID: 20727575
PubMed ID: 20854351
Title: A new SEMA7A variant found in Native Americans with alloantibody.
PubMed ID: 20854351
PubMed ID: 34585848
Title: A homozygous R148W mutation in Semaphorin 7A causes progressive familial intrahepatic cholestasis.
PubMed ID: 34585848
Sequence Information:
- Length: 666
- Mass: 74824
- Checksum: AD3ABE56B5EBE194
- Sequence:
MTPPPPGRAA PSAPRARVPG PPARLGLPLR LRLLLLLWAA AASAQGHLRS GPRIFAVWKG HVGQDRVDFG QTEPHTVLFH EPGSSSVWVG GRGKVYLFDF PEGKNASVRT VNIGSTKGSC LDKRDCENYI TLLERRSEGL LACGTNARHP SCWNLVNGTV VPLGEMRGYA PFSPDENSLV LFEGDEVYST IRKQEYNGKI PRFRRIRGES ELYTSDTVMQ NPQFIKATIV HQDQAYDDKI YYFFREDNPD KNPEAPLNVS RVAQLCRGDQ GGESSLSVSK WNTFLKAMLV CSDAATNKNF NRLQDVFLLP DPSGQWRDTR VYGVFSNPWN YSAVCVYSLG DIDKVFRTSS LKGYHSSLPN PRPGKCLPDQ QPIPTETFQV ADRHPEVAQR VEPMGPLKTP LFHSKYHYQK VAVHRMQASH GETFHVLYLT TDRGTIHKVV EPGEQEHSFA FNIMEIQPFR RAAAIQTMSL DAERRKLYVS SQWEVSQVPL DLCEVYGGGC HGCLMSRDPY CGWDQGRCIS IYSSERSVLQ SINPAEPHKE CPNPKPDKAP LQKVSLAPNS RYYLSCPMES RHATYSWRHK ENVEQSCEPG HQSPNCILFI ENLTAQQYGH YFCEAQEGSY FREAQHWQLL PEDGIMAEHL LGHACALAAS LWLGVLPTLT LGLLVH
Genular Protein ID: 3355678140
Symbol: B3KMH6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 379
- Mass: 42973
- Checksum: D8042EDD79F88C8F
- Sequence:
MLVCSDAATN KNFNRLQDVF LLPDPSGQWR DTRVYGVFSN PWNYSAVCVY SLGDIDKVFR TSSLKGYHSS LPNPRPGKCL PDQQPIPTET FQVADRHPEV AQRVEPMGPL KTPLFHSKYH YQKVAVHRMQ ASHGETFHVL YLTTDRGTIH KVVEPGEQEH SFAFNIMEIQ PFRRAAAIQT MSLDAERRKL YVSSQWEVSQ VPLDLCEVYG GGCHGCLMSR DPYCGWDQGR CISIYSSERS VLQSINPAEP HKECPNPKPD KAPLQKVSLA PNSRYYLSCP MESRHATYSW RHKENVEQSC EPGHQSPNCI LFIENLTAQQ YGHYFCEAQE GSYFREAQHW QLLPEDGIMA EHLLGHACAL AASLWLGVLP TLTLGLLVH
Genular Protein ID: 975830014
Symbol: F5GYX3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
Sequence Information:
- Length: 501
- Mass: 57077
- Checksum: 5EFC380AAB241E70
- Sequence:
MRGYAPFSPD ENSLVLFEGD EVYSTIRKQE YNGKIPRFRR IRGESELYTS DTVMQNPQFI KATIVHQDQA YDDKIYYFFR EDNPDKNPEA PLNVSRVAQL CRGDQGGESS LSVSKWNTFL KAMLVCSDAA TNKNFNRLQD VFLLPDPSGQ WRDTRVYGVF SNPWNYSAVC VYSLGDIDKV FRTSSLKGYH SSLPNPRPGK CLPDQQPIPT ETFQVADRHP EVAQRVEPMG PLKTPLFHSK YHYQKVAVHR MQASHGETFH VLYLTTDRGT IHKVVEPGEQ EHSFAFNIME IQPFRRAAAI QTMSLDAERR KLYVSSQWEV SQVPLDLCEV YGGGCHGCLM SRDPYCGWDQ GRCISIYSSE RSVLQSINPA EPHKECPNPK PDKAPLQKVS LAPNSRYYLS CPMESRHATY SWRHKENVEQ SCEPGHQSPN CILFIENLTA QQYGHYFCEA QEGSYFREAQ HWQLLPEDGI MAEHLLGHAC ALAASLWLGV LPTLTLGLLV H
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.