Details for: ASMTL

Gene ID: 8623

Symbol: ASMTL

Ensembl ID: ENSG00000169093

Description: acetylserotonin O-methyltransferase like

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 41.7286
    Cell Significance Index: -17.1900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 37.9351
    Cell Significance Index: -17.9100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 35.0321
    Cell Significance Index: -18.0200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 7.2350
    Cell Significance Index: 108.4100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.9690
    Cell Significance Index: -15.9900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.2500
    Cell Significance Index: -11.4900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.5321
    Cell Significance Index: -13.9200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 4.5143
    Cell Significance Index: 204.6200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 3.7469
    Cell Significance Index: 77.7300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.9635
    Cell Significance Index: 26.7900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.9611
    Cell Significance Index: 41.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.8596
    Cell Significance Index: 53.5800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.3263
    Cell Significance Index: 144.2600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.3093
    Cell Significance Index: 84.4700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2639
    Cell Significance Index: 205.5600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.2304
    Cell Significance Index: 10.3400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0497
    Cell Significance Index: 63.0200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.9757
    Cell Significance Index: 7.7900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.9531
    Cell Significance Index: 27.9900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.8316
    Cell Significance Index: 29.2200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7861
    Cell Significance Index: 156.0000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7285
    Cell Significance Index: 50.3800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6869
    Cell Significance Index: 130.7300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.6038
    Cell Significance Index: 16.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.5517
    Cell Significance Index: 158.7500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5381
    Cell Significance Index: 73.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5373
    Cell Significance Index: 14.6300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.4889
    Cell Significance Index: 15.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4872
    Cell Significance Index: 48.1900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.4820
    Cell Significance Index: 5.2400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4545
    Cell Significance Index: 23.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3612
    Cell Significance Index: 72.4500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.3443
    Cell Significance Index: 10.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3395
    Cell Significance Index: 185.4000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3346
    Cell Significance Index: 8.6000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3343
    Cell Significance Index: 42.8600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3239
    Cell Significance Index: 6.7800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3111
    Cell Significance Index: 10.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.3034
    Cell Significance Index: 44.1000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2959
    Cell Significance Index: 22.0600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2931
    Cell Significance Index: 36.0400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2736
    Cell Significance Index: 32.2600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2520
    Cell Significance Index: 12.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2437
    Cell Significance Index: 43.9400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.2369
    Cell Significance Index: 3.5700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2320
    Cell Significance Index: 5.8000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2233
    Cell Significance Index: 98.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2203
    Cell Significance Index: 79.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1936
    Cell Significance Index: 14.8600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1894
    Cell Significance Index: 4.9800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1808
    Cell Significance Index: 23.3600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1406
    Cell Significance Index: 1.3000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1403
    Cell Significance Index: 3.7500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1330
    Cell Significance Index: 6.2500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1219
    Cell Significance Index: 8.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1122
    Cell Significance Index: 5.2300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1083
    Cell Significance Index: 6.0800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0928
    Cell Significance Index: 1.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0846
    Cell Significance Index: 0.6900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0809
    Cell Significance Index: 149.2300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0744
    Cell Significance Index: 2.0800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0680
    Cell Significance Index: 1.5700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0667
    Cell Significance Index: 11.4000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0643
    Cell Significance Index: 99.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0499
    Cell Significance Index: 94.0000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.0339
    Cell Significance Index: 0.5200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0268
    Cell Significance Index: 0.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0244
    Cell Significance Index: 1.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0241
    Cell Significance Index: 32.8200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0103
    Cell Significance Index: 6.5400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0018
    Cell Significance Index: 1.3400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0045
    Cell Significance Index: -2.0300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0053
    Cell Significance Index: -3.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0064
    Cell Significance Index: -0.1100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0065
    Cell Significance Index: -0.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0083
    Cell Significance Index: -6.3100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0148
    Cell Significance Index: -0.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0185
    Cell Significance Index: -1.8900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0199
    Cell Significance Index: -11.2400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0310
    Cell Significance Index: -0.8900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0679
    Cell Significance Index: -7.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0732
    Cell Significance Index: -15.4200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0928
    Cell Significance Index: -1.6400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1394
    Cell Significance Index: -14.5100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1507
    Cell Significance Index: -11.9400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1511
    Cell Significance Index: -3.8600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1525
    Cell Significance Index: -2.1900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1642
    Cell Significance Index: -4.4000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1860
    Cell Significance Index: -1.9300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1988
    Cell Significance Index: -2.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2055
    Cell Significance Index: -3.4400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2100
    Cell Significance Index: -2.6900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2175
    Cell Significance Index: -3.7600
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.2531
    Cell Significance Index: -1.3800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2606
    Cell Significance Index: -9.1300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2612
    Cell Significance Index: -4.4000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2639
    Cell Significance Index: -8.6400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2838
    Cell Significance Index: -9.0400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2859
    Cell Significance Index: -17.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Methyltransferase activity**: ASMTL exhibits O-methyltransferase activity, a hallmark of the ASMT enzyme, which is involved in the conversion of acetylserotonin to N-acetylserotonin. 2. **Cellular expression**: ASMTL is expressed in a wide range of cell types, including epithelial cells, immune cells, and germ cells, highlighting its potential involvement in various physiological and pathological processes. 3. **Diphosphatase activity**: ASMTL also possesses diphosphatase activity, which is distinct from its methyltransferase activity, suggesting a complex regulatory mechanism. 4. **Association with biological processes**: ASMTL is linked to several biological processes, including nucleotide metabolic processes, protein binding, and cytosol localization, underscoring its potential role in maintaining cellular homeostasis. **Pathways and Functions:** 1. **Nucleotide metabolic process**: ASMTL's involvement in nucleotide metabolism suggests a role in regulating the synthesis and breakdown of nucleotides, which are essential for various cellular processes, including DNA replication and repair. 2. **Methylation**: ASMTL's O-methyltransferase activity is likely involved in the methylation of nucleotides, which is a critical mechanism for regulating gene expression and maintaining epigenetic marks. 3. **Protein binding**: ASMTL's ability to bind proteins suggests a role in regulating protein function and localization, potentially influencing various cellular processes, including immune response and cellular signaling. 4. **Cytosol localization**: ASMTL's localization to the cytosol implies a role in regulating cytosolic processes, including protein degradation and metabolism. **Clinical Significance:** 1. **Immune regulation**: ASMTL's expression in immune cells, particularly CD1c-positive myeloid dendritic cells, suggests a potential role in regulating immune responses and maintaining immune homeostasis. 2. **Neurological disorders**: ASMTL's expression in retinal cone cells and anterior lens cells raises the possibility of its involvement in neurological disorders, such as retinal degeneration and cataracts. 3. **Cancer research**: ASMTL's expression in epithelial cells and its association with nucleotide metabolic processes suggest a potential role in cancer development and progression. 4. **Epigenetic regulation**: ASMTL's involvement in methylation reactions and its association with epigenetic regulation highlight its potential as a therapeutic target for diseases characterized by epigenetic dysregulation. In conclusion, ASMTL is a gene of methyltransferase activity that plays a complex role in regulating cellular homeostasis and immune regulation. Further studies are necessary to elucidate the functional significance of ASMTL and its potential implications for human disease.

Genular Protein ID: 2954381914

Symbol: ASML_HUMAN

Name: N-acetylserotonin O-methyltransferase-like protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9736779

Title: Gene duplications as a recurrent theme in the evolution of the human pseudoautosomal region 1: isolation of the gene ASMTL.

PubMed ID: 9736779

DOI: 10.1093/hmg/7.11.1771

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24210219

Title: Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides.

PubMed ID: 24210219

DOI: 10.1016/j.chembiol.2013.09.011

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 621
  • Mass: 68857
  • Checksum: 564C2D538F4919EC
  • Sequence:
  • MVLCPVIGKL LHKRVVLASA SPRRQEILSN AGLRFEVVPS KFKEKLDKAS FATPYGYAME 
    TAKQKALEVA NRLYQKDLRA PDVVIGADTI VTVGGLILEK PVDKQDAYRM LSRLSGREHS 
    VFTGVAIVHC SSKDHQLDTR VSEFYEETKV KFSELSEELL WEYVHSGEPM DKAGGYGIQA 
    LGGMLVESVH GDFLNVVGFP LNHFCKQLVK LYYPPRPEDL RRSVKHDSIP AADTFEDLSD 
    VEGGGSEPTQ RDAGSRDEKA EAGEAGQATA EAECHRTRET LPPFPTRLLE LIEGFMLSKG 
    LLTACKLKVF DLLKDEAPQK AADIASKVDA SACGMERLLD ICAAMGLLEK TEQGYSNTET 
    ANVYLASDGE YSLHGFIMHN NDLTWNLFTY LEFAIREGTN QHHRALGKKA EDLFQDAYYQ 
    SPETRLRFMR AMHGMTKLTA CQVATAFNLS RFSSACDVGG CTGALARELA REYPRMQVTV 
    FDLPDIIELA AHFQPPGPQA VQIHFAAGDF FRDPLPSAEL YVLCRILHDW PDDKVHKLLS 
    RVAESCKPGA GLLLVETLLD EEKRVAQRAL MQSLNMLVQT EGKERSLGEY QCLLELHGFH 
    QVQVVHLGGV LDAILATKVA P

Genular Protein ID: 2218523609

Symbol: B3KM43_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 621
  • Mass: 68798
  • Checksum: DC8CD66B4E6E4EA2
  • Sequence:
  • MVLCPVIGKL LHKRVVLASA SPRRQEILSN AGLRFEVVPS KFKEKLDKAS FATPYGYAME 
    TAKQKALEVA NRLYQKDLRA PDVVIGADTI VTVGGLILEK PVDKQDAYRM LSRLSGREHS 
    VFTGVAIVHC SSKDHQLDTR VSEFYGETKV KFSELSEELL WEYVHSGEPM DKAGGYGIQA 
    LGGMLVESVH GDFLNVVGFP LNHFCKQLVK LYYPPRPEDL RRSVKHDSIP AADTFEDLSD 
    VEGGGSEPTQ RDAGSRDEKA EAGEAGQATA EAECHRTRET LPPFPTRLLE LIEGFMLSKG 
    LLTACKLKVF DLLKDEAPQK AADIASKVDA SACGMERLLD ICAAMGLLEK TEQGYSNTET 
    ANVYLASDGE YSLHGFIMHN NDLTWNLFTY LEFAIREGTN QHHRALGKKA EDLFQDAYYQ 
    SPETRLRFMR AMHGMTKLTA CQVATAFNLS RFSSACDMGG CTGALARELA HEYPRMQVTV 
    FDLPDIIELA AHFQPPGPQA VQIHFAAGDF FRDPLPSAEL YVLCRILHDW PDDKVHKLLS 
    RVAESCKPGA GLLLVETLLD EEKRVAQRAL MQSLNMLVQT EGKERSLGEY QCLLELHGFH 
    QVQVVHLGGV LDAILATKVA P

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.