Details for: ABCC3
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 3.95
Marker Score: 3501 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 3.57
Marker Score: 4040 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 2.26
Marker Score: 12136 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.23
Marker Score: 6994 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 2.07
Marker Score: 13235 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.96
Marker Score: 2035 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.89
Marker Score: 12153 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.88
Marker Score: 467 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.82
Marker Score: 7867 - Cell Name: enterocyte (CL0000584)
Fold Change: 1.8
Marker Score: 8646 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.75
Marker Score: 2574 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 1.67
Marker Score: 8789 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.64
Marker Score: 3099 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.57
Marker Score: 1564 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.53
Marker Score: 440.5 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.41
Marker Score: 3209 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.41
Marker Score: 3315 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.39
Marker Score: 2833 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.39
Marker Score: 3399 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.38
Marker Score: 6790 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 1.38
Marker Score: 1321 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.3
Marker Score: 262 - Cell Name: malignant cell (CL0001064)
Fold Change: 1.29
Marker Score: 17371 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 1.29
Marker Score: 3176 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.22
Marker Score: 19099 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.21
Marker Score: 842 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.17
Marker Score: 920 - Cell Name: stem cell (CL0000034)
Fold Change: 1.14
Marker Score: 2713 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 1.13
Marker Score: 474 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.07
Marker Score: 399 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 1.04
Marker Score: 393 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251776 - Cell Name: precursor cell (CL0011115)
Fold Change: 1.01
Marker Score: 246 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71795 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48019 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30405 - Cell Name: epithelial cell (CL0000066)
Fold Change: 0.98
Marker Score: 1556 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 503 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 457 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.97
Marker Score: 1034.5 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2410 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.95
Marker Score: 272 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.94
Marker Score: 1533 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5328 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2740 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.91
Marker Score: 14648 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 322 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5295 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.86
Marker Score: 227 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.83
Marker Score: 891 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.81
Marker Score: 20787 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.81
Marker Score: 619 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.79
Marker Score: 256 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.79
Marker Score: 294.5 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.77
Marker Score: 280 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 392 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.75
Marker Score: 301 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.74
Marker Score: 1571.5 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.73
Marker Score: 469 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.73
Marker Score: 731 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.72
Marker Score: 422 - Cell Name: brush cell (CL0002204)
Fold Change: 0.72
Marker Score: 660 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.72
Marker Score: 757 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.71
Marker Score: 5314 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.71
Marker Score: 2529 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.71
Marker Score: 159 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.69
Marker Score: 331 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 177 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.68
Marker Score: 2868 - Cell Name: basal cell (CL0000646)
Fold Change: 0.65
Marker Score: 844 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 0.64
Marker Score: 3886.5 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.61
Marker Score: 1398 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.6
Marker Score: 329 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.59
Marker Score: 595 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.57
Marker Score: 344 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.57
Marker Score: 1037 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.56
Marker Score: 262 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.56
Marker Score: 145 - Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 0.56
Marker Score: 198 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.55
Marker Score: 781 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 440 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.55
Marker Score: 375 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.54
Marker Score: 345 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 0.54
Marker Score: 1295 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.53
Marker Score: 351 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 0.53
Marker Score: 818 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.53
Marker Score: 135 - Cell Name: lung macrophage (CL1001603)
Fold Change: 0.53
Marker Score: 605 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.53
Marker Score: 158 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.52
Marker Score: 365 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.52
Marker Score: 840 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.52
Marker Score: 350 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.52
Marker Score: 196 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 0.52
Marker Score: 288 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.51
Marker Score: 4486 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.49
Marker Score: 225 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.49
Marker Score: 153 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.48
Marker Score: 127 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.48
Marker Score: 248 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.48
Marker Score: 926
Other Information
Genular Protein ID: 721390770
Symbol: MRP3_HUMAN
Name: ATP-binding cassette sub-family C member 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9813153
Title: Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport.
PubMed ID: 9813153
PubMed ID: 9738950
Title: cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3).
PubMed ID: 9738950
PubMed ID: 9827529
Title: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.
PubMed ID: 9827529
PubMed ID: 9889399
Title: Human MRP3 transporter: identification of the 5'-flanking region, genomic organization and alternative splice variants.
PubMed ID: 9889399
PubMed ID: 10094960
Title: Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane.
PubMed ID: 10094960
PubMed ID: 10359813
Title: MRP3, an organic anion transporter able to transport anti-cancer drugs.
PubMed ID: 10359813
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9270026
Title: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.
PubMed ID: 9270026
PubMed ID: 11581266
Title: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).
PubMed ID: 11581266
PubMed ID: 15083066
Title: Identification and functional characterization of the natural variant MRP3-Arg1297His of human multidrug resistance protein 3 (MRP3/ABCC3).
PubMed ID: 15083066
PubMed ID: 14759258
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28408210
Title: The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.
PubMed ID: 28408210
PubMed ID: 35307651
Title: Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.
PubMed ID: 35307651
Sequence Information:
- Length: 1527
- Mass: 169343
- Checksum: 0D1F879B6F18370C
- Sequence:
MDALCGSGEL GSKFWDSNLS VHTENPDLTP CFQNSLLAWV PCIYLWVALP CYLLYLRHHC RGYIILSHLS KLKMVLGVLL WCVSWADLFY SFHGLVHGRA PAPVFFVTPL VVGVTMLLAT LLIQYERLQG VQSSGVLIIF WFLCVVCAIV PFRSKILLAK AEGEISDPFR FTTFYIHFAL VLSALILACF REKPPFFSAK NVDPNPYPET SAGFLSRLFF WWFTKMAIYG YRHPLEEKDL WSLKEEDRSQ MVVQQLLEAW RKQEKQTARH KASAAPGKNA SGEDEVLLGA RPRPRKPSFL KALLATFGSS FLISACFKLI QDLLSFINPQ LLSILIRFIS NPMAPSWWGF LVAGLMFLCS MMQSLILQHY YHYIFVTGVK FRTGIMGVIY RKALVITNSV KRASTVGEIV NLMSVDAQRF MDLAPFLNLL WSAPLQIILA IYFLWQNLGP SVLAGVAFMV LLIPLNGAVA VKMRAFQVKQ MKLKDSRIKL MSEILNGIKV LKLYAWEPSF LKQVEGIRQG ELQLLRTAAY LHTTTTFTWM CSPFLVTLIT LWVYVYVDPN NVLDAEKAFV SVSLFNILRL PLNMLPQLIS NLTQASVSLK RIQQFLSQEE LDPQSVERKT ISPGYAITIH SGTFTWAQDL PPTLHSLDIQ VPKGALVAVV GPVGCGKSSL VSALLGEMEK LEGKVHMKGS VAYVPQQAWI QNCTLQENVL FGKALNPKRY QQTLEACALL ADLEMLPGGD QTEIGEKGIN LSGGQRQRVS LARAVYSDAD IFLLDDPLSA VDSHVAKHIF DHVIGPEGVL AGKTRVLVTH GISFLPQTDF IIVLADGQVS EMGPYPALLQ RNGSFANFLC NYAPDEDQGH LEDSWTALEG AEDKEALLIE DTLSNHTDLT DNDPVTYVVQ KQFMRQLSAL SSDGEGQGRP VPRRHLGPSE KVQVTEAKAD GALTQEEKAA IGTVELSVFW DYAKAVGLCT TLAICLLYVG QSAAAIGANV WLSAWTNDAM ADSRQNNTSL RLGVYAALGI LQGFLVMLAA MAMAAGGIQA ARVLHQALLH NKIRSPQSFF DTTPSGRILN CFSKDIYVVD EVLAPVILML LNSFFNAIST LVVIMASTPL FTVVILPLAV LYTLVQRFYA ATSRQLKRLE SVSRSPIYSH FSETVTGASV IRAYNRSRDF EIISDTKVDA NQRSCYPYII SNRWLSIGVE FVGNCVVLFA ALFAVIGRSS LNPGLVGLSV SYSLQVTFAL NWMIRMMSDL ESNIVAVERV KEYSKTETEA PWVVEGSRPP EGWPPRGEVE FRNYSVRYRP GLDLVLRDLS LHVHGGEKVG IVGRTGAGKS SMTLCLFRIL EAAKGEIRID GLNVADIGLH DLRSQLTIIP QDPILFSGTL RMNLDPFGSY SEEDIWWALE LSHLHTFVSS QPAGLDFQCS EGGENLSVGQ RQLVCLARAL LRKSRILVLD EATAAIDLET DNLIQATIRT QFDTCTVLTI AHRLNTIMDY TRVLVLDKGV VAEFDSPANL IAARGIFYGM ARDAGLA
Genular Protein ID: 3399721916
Symbol: Q86VN9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 573
- Mass: 64738
- Checksum: B7CD551085F1CA88
- Sequence:
PMDALCGSGE LGSKFWDSNL SVHTENPDLT PCFQNSLLAW VPCIYLWVAL PCYLLYLRHH CRGYIILSHL SKLKMVLGVL LWCVSWADLF YSFHGLVHGR APAPVFFVTP LVVGVTMLLA TLLIQYERLQ GVQSSGVLII FWFLCVVCAI VPFRSKILLA KAEGEISDPF RFTTFYIHFA LVLSALILAC FREKPPFFSA KNVDPNPYPE TSAGFLSRLF FWWFTKMAIY GYRHPLEEKD LWSLKEEDRS QMVVQQLLEA WRKQEKQTAR HKASAAPGKN ASGEDEVLLG ARPRPRKPSF LKALLATFGS SFLISACFKL IQDLLSFINP QLLSILIRFI SNPMAPSWWG FLVAGLMFLC SMMQSLILQH YYHYIFVTGV KFRTGIMGVI YRKALVITNS VKRASTVGEI VNLMSVDAQR FMDLAPFLNL LWSAPLQIIL AIYFLWQNLG PSVLAGVAFM VLLIPLNGAV AVKMRAFQVK QMKLKDSRIK LMSEILNGIK VLKLYAWEPS FLKQVEGIRQ GELQLLRTAA YLHTTTTFTW MCSPFLVRLG TGLGPCLHGS GCPGMARAHW TLP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.