Details for: CTB 30L5 1

Gene ID: 102724339

Symbol: CTB 30L5 1

Ensembl ID: ENSG00000267052

Description: uncharacterized CTB-30L5.1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.4800
    Cell Significance Index: 35.8500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.1826
    Cell Significance Index: 25.9000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.8235
    Cell Significance Index: 12.4100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.7069
    Cell Significance Index: 22.6400
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: 0.3436
    Cell Significance Index: 4.5800
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.2735
    Cell Significance Index: 3.7500
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.2376
    Cell Significance Index: 3.0700
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.2319
    Cell Significance Index: 3.3800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2193
    Cell Significance Index: 4.7500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1978
    Cell Significance Index: 11.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1638
    Cell Significance Index: 4.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1576
    Cell Significance Index: 25.6400
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 0.1304
    Cell Significance Index: 1.6700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1160
    Cell Significance Index: 8.0200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.1045
    Cell Significance Index: 1.4500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.1032
    Cell Significance Index: 1.3000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0817
    Cell Significance Index: 1.7400
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.0532
    Cell Significance Index: 0.7400
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.0442
    Cell Significance Index: 0.9000
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0442
    Cell Significance Index: 0.6200
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0410
    Cell Significance Index: 0.3900
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 0.0336
    Cell Significance Index: 0.3600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0183
    Cell Significance Index: 0.5400
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.0165
    Cell Significance Index: 0.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0053
    Cell Significance Index: 0.4100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0049
    Cell Significance Index: 0.3100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.0045
    Cell Significance Index: 0.1100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0012
    Cell Significance Index: 0.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0010
    Cell Significance Index: 0.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0006
    Cell Significance Index: -0.0300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0010
    Cell Significance Index: -0.0200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0011
    Cell Significance Index: -0.7700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0011
    Cell Significance Index: -0.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0013
    Cell Significance Index: -0.9900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0014
    Cell Significance Index: -0.0200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0015
    Cell Significance Index: -1.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0018
    Cell Significance Index: -1.0000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0018
    Cell Significance Index: -0.2200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0021
    Cell Significance Index: -0.4100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0021
    Cell Significance Index: -1.1300
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0025
    Cell Significance Index: -0.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0028
    Cell Significance Index: -0.8000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0036
    Cell Significance Index: -0.7200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0048
    Cell Significance Index: -1.0100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0053
    Cell Significance Index: -0.6100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0068
    Cell Significance Index: -0.1000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0081
    Cell Significance Index: -1.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0094
    Cell Significance Index: -0.3300
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0109
    Cell Significance Index: -0.1400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0109
    Cell Significance Index: -0.3200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0115
    Cell Significance Index: -0.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0117
    Cell Significance Index: -0.5300
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0117
    Cell Significance Index: -0.1300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0131
    Cell Significance Index: -0.2600
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0133
    Cell Significance Index: -0.2600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0140
    Cell Significance Index: -0.3800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0140
    Cell Significance Index: -0.7100
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0154
    Cell Significance Index: -0.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0161
    Cell Significance Index: -0.7600
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0163
    Cell Significance Index: -0.2200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0176
    Cell Significance Index: -0.5600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0180
    Cell Significance Index: -0.5900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0181
    Cell Significance Index: -0.7400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0184
    Cell Significance Index: -0.3900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0192
    Cell Significance Index: -0.4900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0198
    Cell Significance Index: -1.1100
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: -0.0217
    Cell Significance Index: -0.2200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0218
    Cell Significance Index: -0.4300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0225
    Cell Significance Index: -0.4700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0235
    Cell Significance Index: -0.4900
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0243
    Cell Significance Index: -0.3200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0253
    Cell Significance Index: -0.9300
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0254
    Cell Significance Index: -0.3800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0266
    Cell Significance Index: -0.8400
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0269
    Cell Significance Index: -0.4600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0291
    Cell Significance Index: -0.5800
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.0300
    Cell Significance Index: -0.2700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0306
    Cell Significance Index: -0.4400
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0309
    Cell Significance Index: -0.3200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0320
    Cell Significance Index: -0.9400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0322
    Cell Significance Index: -0.8600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0324
    Cell Significance Index: -0.9300
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -0.0327
    Cell Significance Index: -0.3300
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0340
    Cell Significance Index: -0.4000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0349
    Cell Significance Index: -0.7600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0359
    Cell Significance Index: -0.7200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0367
    Cell Significance Index: -0.4000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0377
    Cell Significance Index: -0.9400
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0382
    Cell Significance Index: -0.3700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0384
    Cell Significance Index: -0.9800
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0384
    Cell Significance Index: -0.9600
  • Cell Name: osteoclast (CL0000092)
    Fold Change: -0.0387
    Cell Significance Index: -0.4000
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0389
    Cell Significance Index: -0.4700
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0390
    Cell Significance Index: -0.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0392
    Cell Significance Index: -0.3200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0403
    Cell Significance Index: -0.9300
  • Cell Name: endothelial stalk cell (CL0002671)
    Fold Change: -0.0411
    Cell Significance Index: -0.4600
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0416
    Cell Significance Index: -0.4300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0420
    Cell Significance Index: -0.8200
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0424
    Cell Significance Index: -0.4900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CTB 30L5.1 is an uncharacterized gene, meaning its function and mechanisms of action are not yet fully understood. Its expression profile, however, reveals a complex pattern of cell-type specificity. Significantly expressed cells include oligodendrocyte precursor cells, blood vessel endothelial cells, enterocytes, goblet cells, and intestinal crypt stem cells. This diversity of cell types suggests that CTB 30L5.1 may play a role in regulating cellular differentiation, proliferation, and survival. **Pathways and Functions:** Several signaling pathways are likely to be involved in the regulation of CTB 30L5.1 expression. The presence of cells involved in immune function, such as oligodendrocyte precursor cells and blood vessel endothelial cells, suggests that CTB 30L5.1 may be involved in immune responses. The expression of CTB 30L5.1 in enterocytes, goblet cells, and intestinal crypt stem cells, on the other hand, implies a role in epithelial homeostasis and the maintenance of the gut barrier. One possible function of CTB 30L5.1 is the regulation of cell-cell interactions and adhesion molecules. The presence of CTB 30L5.1 in cells involved in neural development and immune function suggests that it may play a role in the establishment of tissue-specific cell-cell interactions. Another possibility is that CTB 30L5.1 is involved in the regulation of cellular signaling pathways, such as the PI3K/Akt pathway, which is critical for cell survival and proliferation. **Clinical Significance:** The clinical significance of CTB 30L5.1 is still unclear, but its expression profile suggests that it may be involved in various diseases. For example, alterations in CTB 30L5.1 expression may contribute to immune disorders, such as multiple sclerosis, which is characterized by demyelination and inflammation in the central nervous system. Additionally, CTB 30L5.1 may play a role in the development of gastrointestinal disorders, such as inflammatory bowel disease, which is characterized by chronic inflammation and damage to the gut epithelium. Furthermore, the expression of CTB 30L5.1 in intestinal crypt stem cells suggests that it may be involved in the maintenance of gut homeostasis and the prevention of cancer. Alterations in CTB 30L5.1 expression may contribute to the development of colorectal cancer, which is one of the most common types of cancer worldwide. In conclusion, while the functional significance of CTB 30L5.1 remains unclear, its expression profile suggests that it may play a critical role in regulating cellular differentiation, proliferation, and survival. Further research is needed to elucidate the mechanisms of action of CTB 30L5.1 and its clinical implications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.