Details for: CYP19A1

Gene ID: 1588

Symbol: CYP19A1

Ensembl ID: ENSG00000137869

Description: cytochrome P450 family 19 subfamily A member 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 3.32
    Marker Score: 1075
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 3.11
    Marker Score: 2550
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.57
    Marker Score: 8404
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1168
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.58
    Marker Score: 3213
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.38
    Marker Score: 1371
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 869
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.26
    Marker Score: 854
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.21
    Marker Score: 18976
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.17
    Marker Score: 487
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4814
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.13
    Marker Score: 2146
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.09
    Marker Score: 503
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.05
    Marker Score: 553
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 795.5
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251808
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71826
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48051
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 509
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30408
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 462
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5337
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 374
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2741
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 326
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.9
    Marker Score: 291
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5296
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.82
    Marker Score: 1693
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.8
    Marker Score: 5290
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1261
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 708
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.77
    Marker Score: 397
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.76
    Marker Score: 501
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 462
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 179
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.69
    Marker Score: 413
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.69
    Marker Score: 327
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.67
    Marker Score: 2635
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.62
    Marker Score: 196
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.61
    Marker Score: 269
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 446
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 148
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.56
    Marker Score: 232
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.55
    Marker Score: 174
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.51
    Marker Score: 5182
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.48
    Marker Score: 118
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.47
    Marker Score: 134
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.4
    Marker Score: 384
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.39
    Marker Score: 228
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.39
    Marker Score: 443
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.38
    Marker Score: 96
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.37
    Marker Score: 135
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 372
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.36
    Marker Score: 2175
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.36
    Marker Score: 656
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.32
    Marker Score: 397
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.31
    Marker Score: 80
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.27
    Marker Score: 271
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.25
    Marker Score: 583
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.25
    Marker Score: 110
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.23
    Marker Score: 145
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.23
    Marker Score: 65
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.23
    Marker Score: 155
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.22
    Marker Score: 83
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.22
    Marker Score: 131
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 74
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.22
    Marker Score: 117
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.21
    Marker Score: 96
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.2
    Marker Score: 506
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.19
    Marker Score: 58
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.18
    Marker Score: 282.5
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.18
    Marker Score: 320
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.18
    Marker Score: 86
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.18
    Marker Score: 88
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.17
    Marker Score: 43
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.17
    Marker Score: 92
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.17
    Marker Score: 69
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.15
    Marker Score: 96
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.14
    Marker Score: 585
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.14
    Marker Score: 134
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.14
    Marker Score: 154
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.14
    Marker Score: 151
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.12
    Marker Score: 72
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.12
    Marker Score: 75
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.12
    Marker Score: 109
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.12
    Marker Score: 107
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.11
    Marker Score: 114
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.11
    Marker Score: 51
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.11
    Marker Score: 24
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.11
    Marker Score: 118
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.11
    Marker Score: 101
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.1
    Marker Score: 51
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.1
    Marker Score: 88.5
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.1
    Marker Score: 68
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.1
    Marker Score: 20
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.1
    Marker Score: 40
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.1
    Marker Score: 120
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.1
    Marker Score: 96
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.09
    Marker Score: 25

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Other Information

## Summary CYP19A1 is a cytochrome P450 enzyme that plays a crucial role in various biological processes. It is significantly expressed in cells of the reproductive tract, liver, and small intestine. ## Key characteristics * CYP19A1 is a member of the cytochrome P450 family 19 subfamily A. * It is a heterodimeric enzyme composed of two subunits, alpha and beta. * The alpha subunit is responsible for the catalytic activity, while the beta subunit is involved in protein-protein interactions. * CYP19A1 is a key enzyme in the metabolism of various drugs and chemicals, including estrogens, androgens, and other hormones. ## Pathways and functions * CYP19A1 is involved in the following pathways: * Aromatase activity: CYP19A1 is responsible for the conversion of androgens to estrogen in the female reproductive tract. * Biological oxidations: It also plays a role in the metabolism of various biomolecules, including cholesterol, and is involved in the generation of reactive oxygen species. * Electron transfer activity: CYP19A1 is involved in the electron transfer activity of the cytochrome P450 family, catalyzing the reduction of various substrates. * Endogenous sterols: CYP19A1 is involved in the biosynthesis of estrogens in the female reproductive tract. * Estrogen biosynthesis: It is also involved in the biosynthesis of androgens in the male reproductive tract. ## Clinical significance * Mutations in CYP19A1 have been linked to several diseases of metabolism, including breast cancer, prostate cancer, and endometriosis. * CYP19A1 inhibitors are currently being investigated as potential therapeutic agents for these disorders. * Dysregulation of CYP19A1 activity has been implicated in the pathogenesis of several diseases, including obesity, metabolic syndrome, and cardiovascular disease. **Overall, CYP19A1 is a critical enzyme with important roles in various biological processes, including the metabolism of hormones and the generation of reactive oxygen species.**

Genular Protein ID: 3303549204

Symbol: CP19A_HUMAN

Name: CYPXIX

UniProtKB Accession Codes:

P11511 Q16731 Q3B764 Q58FA0 Q8IYJ7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 70 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 52 DrugCentral 1 EC 2 EMBL 19 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 17 PDBsum 11 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 3 RefSeq 11 Rhea 36 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2973313

Title: Cloning of a complete cDNA encoding human aromatase: immunochemical identification and sequence analysis.

PubMed ID: 2973313

DOI: 10.1016/s0006-291x(88)80903-3

PubMed ID: 3390233

Title: Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15.

PubMed ID: 3390233

DOI: 10.1089/dna.1988.7.27

PubMed ID: 2848247

Title: Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells.

PubMed ID: 2848247

DOI: 10.1073/pnas.85.23.8948

PubMed ID: 2541021

Title: Alternative usage of different poly(A) addition signals for two major species of mRNA encoding human aromatase P-450.

PubMed ID: 2541021

DOI: 10.1016/0014-5793(89)81373-0

PubMed ID: 2808431

Title: Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis.

PubMed ID: 2808431

DOI: 10.1016/s0021-9258(19)47313-4

PubMed ID: 2691883

Title: Expression of human placental aromatase in Saccharomyces cerevisiae.

PubMed ID: 2691883

DOI: 10.1210/mend-3-9-1477

PubMed ID: 1371509

Title: Biochemical and molecular genetic analyses on placental aromatase (P-450AROM) deficiency.

PubMed ID: 1371509

DOI: 10.1016/s0021-9258(18)42900-6

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3018730

Title: Isolation and characterization of a complementary DNA specific for human aromatase-system cytochrome P-450 mRNA.

PubMed ID: 3018730

DOI: 10.1073/pnas.83.17.6387

PubMed ID: 3653507

Title: Sequencing of cDNA inserts encoding aromatase cytochrome P-450 (P-450AROM).

PubMed ID: 3653507

DOI: 10.1016/0303-7207(87)90054-2

PubMed ID: 2040633

Title: Tissue-specific expression of human P-450AROM. The promoter responsible for expression in adipose tissue is different from that utilized in placenta.

PubMed ID: 2040633

DOI: 10.1016/s0021-9258(18)99159-3

PubMed ID: 7690033

Title: Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

PubMed ID: 7690033

DOI: 10.1016/s0021-9258(19)36538-x

PubMed ID: 3964273

Title: Amino terminal sequence analysis of human placenta aromatase.

PubMed ID: 3964273

DOI: 10.1016/0006-291x(86)90987-3

PubMed ID: 8117272

Title: Novel exon 1 of the aromatase gene specific for aromatase transcripts in human brain.

PubMed ID: 8117272

DOI: 10.1006/bbrc.1994.1163

PubMed ID: 20385561

Title: Kinetic analysis of the three-step steroid aromatase reaction of human cytochrome P450 19A1.

PubMed ID: 20385561

DOI: 10.1074/jbc.m110.123711

PubMed ID: 22773874

Title: Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4.

PubMed ID: 22773874

DOI: 10.1074/jbc.m112.390047

PubMed ID: 19129847

Title: Structural basis for androgen specificity and oestrogen synthesis in human aromatase.

PubMed ID: 19129847

DOI: 10.1038/nature07614

PubMed ID: 8265607

Title: Molecular basis of aromatase deficiency in an adult female with sexual infantilism and polycystic ovaries.

PubMed ID: 8265607

DOI: 10.1073/pnas.90.24.11673

PubMed ID: 8530621

Title: Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens.

PubMed ID: 8530621

DOI: 10.1210/jcem.80.12.8530621

PubMed ID: 9211678

Title: Effect of testosterone and estradiol in a man with aromatase deficiency.

PubMed ID: 9211678

DOI: 10.1056/nejm199707103370204

PubMed ID: 9352581

Title: Arginine-cysteine polymorphism at codon 264 of the human CYP19 gene does not affect aromatase activity.

PubMed ID: 9352581

DOI: 10.1097/00008571-199710000-00014

PubMed ID: 10956405

Title: Breast cancer risk associated with polymorphism in CYP19 in Japanese women.

PubMed ID: 10956405

DOI: 10.1002/1097-0215(20000720)89:4<325::aid-ijc2>3.0.co;2-3

PubMed ID: 18987736

Title: DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.

PubMed ID: 18987736

DOI: 10.1038/nature07485

PubMed ID: 24705274

Title: Characterization of a novel CYP19A1 (aromatase) R192H mutation causing virilization of a 46,XX newborn, undervirilization of the 46,XY brother, but no virilization of the mother during pregnancies.

PubMed ID: 24705274

DOI: 10.1016/j.mce.2014.03.008

PubMed ID: 27657680

Title: A dominant variant in DMXL2 is linked to nonsyndromic hearing loss.

PubMed ID: 27657680

DOI: 10.1038/gim.2016.142

PubMed ID: 27702664

Title: Impact of R264C and R264H polymorphisms in human aromatase function.

PubMed ID: 27702664

DOI: 10.1016/j.jsbmb.2016.09.022

Sequence Information:

  • Length: 503
  • Mass: 57883
  • Checksum: 9BD9B28651D9A69A
  • Sequence:
    • MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI 
SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL 
GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN 
ESGYVDVLTL LRRVMLDTSN TLFLRIPLDE SAIVVKIQGY FDAWQALLIK PDIFFKISWL 
YKKYEKSVKD LKDAIEVLIA EKRRRISTEE KLEECMDFAT ELILAEKRGD LTRENVNQCI 
LEMLIAAPDT MSVSLFFMLF LIAKHPNVEE AIIKEIQTVI GERDIKIDDI QKLKVMENFI 
YESMRYQPVV DLVMRKALED DVIDGYPVKK GTNIILNIGR MHRLEFFPKP NEFTLENFAK 
NVPYRYFQPF GFGPRGCAGK YIAMVMMKAI LVTLLRRFHV KTLQGQCVES IQKIHDLSLH 
PDETKNMLEM IFTPRNSDRC LEH

Genular Protein ID: 2481404616

Symbol: Q05CU4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q05CU4

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 5 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 360
  • Mass: 41213
  • Checksum: 2B19766F60E13881
  • Sequence:
    • MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI 
SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL 
GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN 
ESGYVDVLTL LRRVMLDTSN TLFLRIPLDE SAIVVKIQGY FDAWQALLIK PDIFFKISWL 
YKKYEKSVKD LKDAIEVLIA EKRRRISTEE KLEECMDFAT ELILAEKRGD LTRENVNQCI 
LEMLIAAPDT MSVSLFFMLF LIAKHPNVEE AIIKEIQTVI GERDIKIDDI QKKKKKKKKK

Genular Protein ID: 3666456787

Symbol: Q8TCA4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8TCA4

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 5 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 ProteomicsDB 1 RefSeq 2 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 181
  • Mass: 20221
  • Checksum: 6D76CF9015E1AB65
  • Sequence:
    • MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI 
SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL 
GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLLLFTPASV 
N

Genular Protein ID: 1515869527

Symbol: Q8IYG4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8IYG4

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 503
  • Mass: 57873
  • Checksum: 58297DBA53610411
  • Sequence:
    • MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI 
SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL 
GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN 
ESGYVDVLTL LRRVMLDTSN TLFLRISLDE SAIVVKIQGY FDAWQALLIK PDIFFKISWL 
YKKYEKSVKD LKDAIEVLIA EKRRRISTEE KLEECMDFAT ELILAEKRGD LTRENVNQCI 
LEMLIAAPDT MSVSLFFMLF LIAKHPNVEE AIIKEIQTVI GERDIKIDDI QKLKVMENFI 
YESMRYQPVV DLVMRKALED DVIDGYPVKK GTNIILNIGR MHRLEFFPKP NEFTLENFAK 
NVPYRYFQPF GFGPRGCAGK YIAMVMMKAI LVTLLRRFHV KTLQGQCVES IQKIHDLSLH 
PDETKNMLEM IFTPRNSDRC LEH

Genular Protein ID: 4251413454

Symbol: A8K6W3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K6W3

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 DNASU 1 EMBL 2 GO 4 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SUPFAM 1

Sequence Information:

  • Length: 503
  • Mass: 57869
  • Checksum: CBD8E38570D95CF4
  • Sequence:
    • MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI 
SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL 
GLQCIGMHEN GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN 
ESGYVDVLTL LRRVMLDTSN TLFLRIPLDE SAIVVKIQGY FDAWQALLIK PDIFFKISWL 
YKKYEKSVKD LKDAIEVLIA EKRRRISTEE KLEECMDFAT ELILAEKRGD LTRENVNQCI 
LEMLIAAPDT MSVSLFFMLF LIAKHPNVEE AIIKEIQTVI GERDIKIDDI QKLKVMENFI 
YESMRYQPVV DLVMRKALED DVIDGYPVKK GTNIILNIGR MHRLEFFPKP NEFTLENFAK 
NVPYRYFQPF GFGPRGCAGK YIAMVMMKAI LVTLLRRFHV KTLQGQCVES IQKIHDLSLH 
PDETKNMLEM IFTPRNSDRC LEH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.