Details for: FUT3

Gene ID: 2525

Symbol: FUT3

Ensembl ID: ENSG00000171124

Description: fucosyltransferase 3 (Lewis blood group)

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 12.0413
    Cell Significance Index: -8.0800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 4.7050
    Cell Significance Index: 70.5000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.4123
    Cell Significance Index: -11.8200
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 3.7993
    Cell Significance Index: 28.8100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 3.6233
    Cell Significance Index: 104.4000
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 3.0931
    Cell Significance Index: 18.5400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.9905
    Cell Significance Index: 135.5500
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 2.0658
    Cell Significance Index: 20.8400
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 1.7836
    Cell Significance Index: 19.3300
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 1.7142
    Cell Significance Index: 21.6600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.5229
    Cell Significance Index: 1375.0800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.1870
    Cell Significance Index: 14.1500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.9734
    Cell Significance Index: 34.2100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.9642
    Cell Significance Index: 60.7700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8532
    Cell Significance Index: 44.3200
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.7208
    Cell Significance Index: 7.4400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.6104
    Cell Significance Index: 19.5500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5973
    Cell Significance Index: 12.7200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4517
    Cell Significance Index: 4.1600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3463
    Cell Significance Index: 37.6700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2302
    Cell Significance Index: 22.7700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.2248
    Cell Significance Index: 3.2000
  • Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
    Fold Change: 0.2082
    Cell Significance Index: 1.3900
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.1895
    Cell Significance Index: 3.2400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1637
    Cell Significance Index: 4.5700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1227
    Cell Significance Index: 5.7200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0905
    Cell Significance Index: 17.2300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0733
    Cell Significance Index: 40.0400
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.0690
    Cell Significance Index: 0.5700
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.0568
    Cell Significance Index: 0.3700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0367
    Cell Significance Index: 1.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0253
    Cell Significance Index: 2.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0247
    Cell Significance Index: 4.4500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0204
    Cell Significance Index: 15.4200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0055
    Cell Significance Index: 0.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0005
    Cell Significance Index: -0.0200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0005
    Cell Significance Index: -0.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0028
    Cell Significance Index: -5.2300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0040
    Cell Significance Index: -6.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0054
    Cell Significance Index: -9.9800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0059
    Cell Significance Index: -0.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0072
    Cell Significance Index: -9.8100
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0081
    Cell Significance Index: -0.0500
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0102
    Cell Significance Index: -0.1400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0131
    Cell Significance Index: -9.6800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0137
    Cell Significance Index: -10.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0141
    Cell Significance Index: -7.9500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0145
    Cell Significance Index: -1.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0148
    Cell Significance Index: -9.4200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0152
    Cell Significance Index: -2.5900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0171
    Cell Significance Index: -0.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0182
    Cell Significance Index: -0.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0190
    Cell Significance Index: -6.8300
  • Cell Name: eosinophil (CL0000771)
    Fold Change: -0.0204
    Cell Significance Index: -0.1800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0250
    Cell Significance Index: -0.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0251
    Cell Significance Index: -4.9900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0270
    Cell Significance Index: -12.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0288
    Cell Significance Index: -8.3000
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.0301
    Cell Significance Index: -0.2000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0304
    Cell Significance Index: -13.4600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0380
    Cell Significance Index: -0.9500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0393
    Cell Significance Index: -7.8800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0478
    Cell Significance Index: -10.0700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0520
    Cell Significance Index: -7.1400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0529
    Cell Significance Index: -1.4400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0574
    Cell Significance Index: -1.1900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0607
    Cell Significance Index: -0.6400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0629
    Cell Significance Index: -9.1500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0696
    Cell Significance Index: -8.9900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0705
    Cell Significance Index: -7.3400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0893
    Cell Significance Index: -9.1300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0937
    Cell Significance Index: -3.4400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1002
    Cell Significance Index: -2.9500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1021
    Cell Significance Index: -1.1600
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.1051
    Cell Significance Index: -1.3600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1232
    Cell Significance Index: -0.8400
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.1265
    Cell Significance Index: -0.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1266
    Cell Significance Index: -10.0300
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.1320
    Cell Significance Index: -1.4500
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.1348
    Cell Significance Index: -0.9800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1393
    Cell Significance Index: -8.5400
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.1432
    Cell Significance Index: -1.3000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1534
    Cell Significance Index: -8.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1617
    Cell Significance Index: -8.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1668
    Cell Significance Index: -12.4400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1692
    Cell Significance Index: -7.9500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1713
    Cell Significance Index: -4.1500
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.1785
    Cell Significance Index: -1.1100
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: -0.1813
    Cell Significance Index: -1.3800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1866
    Cell Significance Index: -12.0400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1953
    Cell Significance Index: -13.8100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1965
    Cell Significance Index: -2.3900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1965
    Cell Significance Index: -6.8900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1998
    Cell Significance Index: -5.0900
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.2005
    Cell Significance Index: -2.1300
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.2274
    Cell Significance Index: -1.9700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2359
    Cell Significance Index: -6.3000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2417
    Cell Significance Index: -4.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2519
    Cell Significance Index: -6.7500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2542
    Cell Significance Index: -11.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Fucosyltransferase activity:** FUT3 is a type of fucosyltransferase enzyme that catalyzes the transfer of fucose sugar molecules to specific glycoproteins and glycolipids. 2. **Blood group systems biosynthesis:** FUT3 is involved in the synthesis of Lewis blood group antigens, which are present on the surface of red blood cells and other tissues. 3. **Cell-cell recognition:** Fucosylation of glycoproteins and glycolipids plays a crucial role in cell-cell recognition and adhesion, particularly in the immune system. 4. **Glycosylation:** FUT3 is involved in the glycosylation of proteins and lipids, which is essential for their proper functioning and stability. **Pathways and Functions:** 1. **3-galactosyl-n-acetylglucosaminide 4-alpha-l-fucosyltransferase activity:** FUT3 catalyzes the transfer of fucose sugar molecules to 3-galactosyl-n-acetylglucosaminide, a precursor molecule for the synthesis of Lewis blood group antigens. 2. **4-galactosyl-n-acetylglucosaminide 3-alpha-l-fucosyltransferase activity:** FUT3 is also involved in the transfer of fucose sugar molecules to 4-galactosyl-n-acetylglucosaminide, another precursor molecule for the synthesis of Lewis blood group antigens. 3. **Alpha-(1->3)-fucosyltransferase activity:** FUT3 catalyzes the transfer of fucose sugar molecules to alpha-(1->3)-linked glycoproteins and glycolipids, which is essential for cell-cell recognition and adhesion. 4. **Asparagine n-linked glycosylation:** FUT3 is involved in the glycosylation of asparagine-linked proteins, which is essential for their proper functioning and stability. 5. **Cell-cell recognition:** Fucosylation of glycoproteins and glycolipids plays a crucial role in cell-cell recognition and adhesion, particularly in the immune system. **Clinical Significance:** 1. **Cancer:** Dysregulation of FUT3 has been implicated in various cancers, including leukemia, lymphoma, and breast cancer. 2. **Autoimmune disorders:** FUT3 has been implicated in autoimmune disorders, including rheumatoid arthritis and lupus. 3. **Inflammatory conditions:** FUT3 has been implicated in inflammatory conditions, including asthma and allergic reactions. 4. **Blood group systems:** FUT3 is involved in the synthesis of Lewis blood group antigens, which are present on the surface of red blood cells and other tissues. 5. **Immunological processes:** Fucosylation of glycoproteins and glycolipids plays a crucial role in immune responses, including cell-cell recognition and adhesion. In conclusion, the FUT3 gene plays a crucial role in various biological processes, including cell-cell recognition, immune responses, and blood group systems. Its dysregulation has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions. Further research is needed to fully understand the mechanisms of FUT3 and its role in human health and disease.

Genular Protein ID: 535020183

Symbol: FUT3_HUMAN

Name: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase

UniProtKB Accession Codes:

P21217 B5U7U9 B5U7V0 Q32NE7 Q99448 Q99449

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 1 CTD 1 ChEBI 70 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 14 Ensembl 8 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 2 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRIDE 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 7 Rhea 28 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1977660

Title: A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.

PubMed ID: 1977660

DOI: 10.1101/gad.4.8.1288

PubMed ID: 8240337

Title: Alpha (1,3/1,4)fucosyltransferase (FucT-III) gene is inactivated by a single amino acid substitution in Lewis histo-blood type negative individuals.

PubMed ID: 8240337

DOI: 10.1006/bbrc.1993.2295

PubMed ID: 7650030

Title: Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.

PubMed ID: 7650030

DOI: 10.1074/jbc.270.34.20112

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7721776

Title: Acceptor specificity of different length constructs of human recombinant alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolyzing activity.

PubMed ID: 7721776

DOI: 10.1074/jbc.270.15.8712

PubMed ID: 11058871

Title: Peritoneal colonization by human pancreatic cancer cells is inhibited by antisense FUT3 sequence.

PubMed ID: 11058871

DOI: 10.1002/1097-0215(20001115)88:4<558::aid-ijc7>3.0.co;2-b

PubMed ID: 12668675

Title: Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.

PubMed ID: 12668675

DOI: 10.1074/jbc.m211034200

PubMed ID: 27453266

Title: Effect of FUT3 gene silencing with miRNA on proliferation, invasion and migration abilities of human KATO-III gastric cancer cell line.

PubMed ID: 27453266

PubMed ID: 29593094

Title: Distinct human alpha(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

PubMed ID: 29593094

DOI: 10.1074/jbc.ra117.000775

PubMed ID: 8240322

Title: Genotypic heterogeneity among Lewis negative individuals.

PubMed ID: 8240322

DOI: 10.1006/bbrc.1993.2280

PubMed ID: 8219240

Title: Analysis of Lewis fucosyltransferase genes from the human gastric mucosa of Lewis-positive and -negative individuals.

PubMed ID: 8219240

PubMed ID: 8063716

Title: Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees.

PubMed ID: 8063716

DOI: 10.1016/s0021-9258(17)31919-1

PubMed ID: 7961897

Title: Molecular genetic analysis of the human Lewis histo-blood group system.

PubMed ID: 7961897

DOI: 10.1016/s0021-9258(19)62041-7

PubMed ID: 8801770

Title: DNA sequencing and screening for point mutations in the human Lewis 'FUT3' gene enables molecular genotyping of the human Lewis blood group system.

PubMed ID: 8801770

DOI: 10.1111/j.1423-0410.1996.tb01300.x

PubMed ID: 9268337

Title: Significance of individual point mutations, T202C and C314T, in the human Lewis 'FUT3' gene for expression of Lewis antigens by the human alpha'1,3/1,4'-fucosyltransferase, Fuc-TIII.

PubMed ID: 9268337

DOI: 10.1074/jbc.272.35.21994

PubMed ID: 10211701

Title: Significance of each of three missense mutations, G484A, G667A, and G808A, present in an inactive allele of the human Lewis gene (FUT3) for alpha(1,3/1,4)fucosyltransferase inactivation.

PubMed ID: 10211701

DOI: 10.1023/a:1006981724233

PubMed ID: 9703429

Title: Five novel missense mutations of the Lewis gene 'FUT3' in African 'Xhosa' and Caucasian populations in South Africa.

PubMed ID: 9703429

DOI: 10.1007/s004390050760

Sequence Information:

  • Length: 361
  • Mass: 42117
  • Checksum: 5EC3A1E3DBA51842
  • Sequence:
    • MDPLGAAKPQ WPWRRCLAAL LFQLLVAVCF FSYLRVSRDD ATGSPRAPSG SSRQDTTPTR 
PTLLILLRTW PFHIPVALSR CSEMVPGTAD CHITADRKVY PQADMVIVHH WDIMSNPKSR 
LPPSPRPQGQ RWIWFNLEPP PNCQHLEALD RYFNLTMSYR SDSDIFTPYG WLEPWSGQPA 
HPPLNLSAKT ELVAWAVSNW KPDSARVRYY QSLQAHLKVD VYGRSHKPLP KGTMMETLSR 
YKFYLAFENS LHPDYITEKL WRNALEAWAV PVVLGPSRSN YERFLPPDAF IHVDDFQSPK 
DLARYLQELD KDHARYLSYF RWRETLRPRS FSWALDFCKA CWKLQQESRY QTVRSIAAWF 
T

Genular Protein ID: 553090567

Symbol: A8K737_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K737

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CAZy 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 GO 4 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 3 PharmGKB 1 RefSeq 4 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 UniPathway 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 361
  • Mass: 42117
  • Checksum: BF4398044F19C284
  • Sequence:
    • MDPLGAAKPQ WPWRRCLAAL LFQLLVAVCF FSYLRVSRDD ATGSPRAPSG SSRQDTTPTR 
PTLLILLWTW PFHIPVALSR CSEMVPGTAD CHITADRKVY PQADTVIVHH WDIMSNPKSR 
LPPSPRPQGQ RWIWFNLEPP PNCQHLEALD RYFNLTMSYR SDSDIFTPYG WLEPWSGQPA 
HPPLNLSAKT ELVAWAVSNW KPDSARVRYY QSLQAHLKVD VYGRSHKPLP KGTMMETLSR 
YKFYLAFENS LHPDYITEKL WRNALEAWAV PVVLGPSRSN YERFLPPDAF IHVDDFQSPK 
DLARYLQELD KDHARYLSYF RWRETLRPRS FSWALDFCKA CWKLQQESRY QTVRSIAAWF 
T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.