Details for: KLK2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 6.2472
Cell Significance Index: 64.6500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.8200
Cell Significance Index: 111.5800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.5906
Cell Significance Index: 34.4600 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.2864
Cell Significance Index: 31.1600 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.1589
Cell Significance Index: 7.1500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.9841
Cell Significance Index: 14.8300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5576
Cell Significance Index: 106.1200 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.5069
Cell Significance Index: 4.5000 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.4745
Cell Significance Index: 7.6900 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.3948
Cell Significance Index: 1.8800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.3728
Cell Significance Index: 7.9400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3376
Cell Significance Index: 33.4000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2861
Cell Significance Index: 258.3400 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.2659
Cell Significance Index: 1.9100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2187
Cell Significance Index: 23.7900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2115
Cell Significance Index: 12.7000 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.2012
Cell Significance Index: 1.2500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1869
Cell Significance Index: 30.3900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1397
Cell Significance Index: 2.0000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1236
Cell Significance Index: 8.5500 - Cell Name: sebaceous gland cell (CL2000021)
Fold Change: 0.0804
Cell Significance Index: 0.1000 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.0627
Cell Significance Index: 0.6500 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.0571
Cell Significance Index: 0.1300 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.0339
Cell Significance Index: 0.3600 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 0.0290
Cell Significance Index: 0.3200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0276
Cell Significance Index: 0.9700 - Cell Name: helper T cell (CL0000912)
Fold Change: 0.0197
Cell Significance Index: 0.2800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0163
Cell Significance Index: 2.0100 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 0.0137
Cell Significance Index: 0.1500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0131
Cell Significance Index: 2.3700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0088
Cell Significance Index: 0.2400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.0061
Cell Significance Index: 0.0900 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0060
Cell Significance Index: 0.6100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0032
Cell Significance Index: 0.0800 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: 0.0016
Cell Significance Index: 0.0200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.0003
Cell Significance Index: 0.0100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0003
Cell Significance Index: -0.0100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0007
Cell Significance Index: -0.0300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0010
Cell Significance Index: -1.8500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0018
Cell Significance Index: -3.2700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0018
Cell Significance Index: -2.8300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0022
Cell Significance Index: -1.6100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0023
Cell Significance Index: -3.1900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0025
Cell Significance Index: -1.5700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0031
Cell Significance Index: -1.7800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0031
Cell Significance Index: -2.3300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0034
Cell Significance Index: -0.0700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0034
Cell Significance Index: -0.0900 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0034
Cell Significance Index: -1.8300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0034
Cell Significance Index: -0.0900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0038
Cell Significance Index: -0.1100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0043
Cell Significance Index: -1.9700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0044
Cell Significance Index: -0.6000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0046
Cell Significance Index: -1.6500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0047
Cell Significance Index: -0.2200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0061
Cell Significance Index: -1.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0061
Cell Significance Index: -1.0500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0063
Cell Significance Index: -1.8100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0070
Cell Significance Index: -0.2900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0073
Cell Significance Index: -0.3700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0088
Cell Significance Index: -1.2800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0091
Cell Significance Index: -1.8400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0093
Cell Significance Index: -1.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0099
Cell Significance Index: -0.7400 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: -0.0121
Cell Significance Index: -0.1400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0122
Cell Significance Index: -1.4000 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0146
Cell Significance Index: -0.1600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0152
Cell Significance Index: -0.7900 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: -0.0167
Cell Significance Index: -0.2100 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0183
Cell Significance Index: -0.3200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0189
Cell Significance Index: -2.2300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0192
Cell Significance Index: -2.4800 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.0203
Cell Significance Index: -0.1300 - Cell Name: endocrine cell (CL0000163)
Fold Change: -0.0215
Cell Significance Index: -0.2600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0225
Cell Significance Index: -2.3500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0234
Cell Significance Index: -0.7400 - Cell Name: taste receptor cell (CL0000209)
Fold Change: -0.0249
Cell Significance Index: -0.2900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0268
Cell Significance Index: -0.5600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0270
Cell Significance Index: -1.7400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0278
Cell Significance Index: -0.3200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0280
Cell Significance Index: -1.8800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0293
Cell Significance Index: -0.9400 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0299
Cell Significance Index: -0.4800 - Cell Name: PP cell (CL0000696)
Fold Change: -0.0325
Cell Significance Index: -0.3300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0335
Cell Significance Index: -1.5800 - Cell Name: ionocyte (CL0005006)
Fold Change: -0.0344
Cell Significance Index: -0.3600 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0369
Cell Significance Index: -0.6200 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.0377
Cell Significance Index: -0.5500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0389
Cell Significance Index: -0.7600 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.0392
Cell Significance Index: -0.6700 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: -0.0392
Cell Significance Index: -0.3900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0452
Cell Significance Index: -1.5700 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.0461
Cell Significance Index: -0.4900 - Cell Name: neuroplacodal cell (CL0000032)
Fold Change: -0.0463
Cell Significance Index: -0.5700 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0496
Cell Significance Index: -0.7200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0506
Cell Significance Index: -2.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0507
Cell Significance Index: -2.6600 - Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
Fold Change: -0.0509
Cell Significance Index: -0.5500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0521
Cell Significance Index: -1.1400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0540
Cell Significance Index: -1.8900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1714494839
Symbol: KLK2_HUMAN
Name: Kallikrein-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2824146
Title: Primary structure of a human glandular kallikrein gene.
PubMed ID: 2824146
PubMed ID: 1726490
Title: Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species.
PubMed ID: 1726490
PubMed ID: 10544017
Title: Identification of three new alternate human kallikrein 2 transcripts: evidence of long transcript and alternative splicing.
PubMed ID: 10544017
PubMed ID: 11054574
Title: Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.
PubMed ID: 11054574
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14759258
PubMed ID: 10391209
Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.
PubMed ID: 10391209
DOI: 10.1038/10290
Sequence Information:
- Length: 261
- Mass: 28671
- Checksum: 9CF7F4A1162EF42D
- Sequence:
MWDLVLSIAL SVGCTGAVPL IQSRIVGGWE CEKHSQPWQV AVYSHGWAHC GGVLVHPQWV LTAAHCLKKN SQVWLGRHNL FEPEDTGQRV PVSHSFPHPL YNMSLLKHQS LRPDEDSSHD LMLLRLSEPA KITDVVKVLG LPTQEPALGT TCYASGWGSI EPEEFLRPRS LQCVSLHLLS NDMCARAYSE KVTEFMLCAG LWTGGKDTCG GDSGGPLVCN GVLQGITSWG PEPCALPEKP AVYTKVVHYR KWIKDTIAAN P
Genular Protein ID: 3058167978
Symbol: B4DU77_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 244
- Mass: 26421
- Checksum: 078D1FB643B276AD
- Sequence:
MGTLWGCPGA PPVGAHSCPL PKEVSRTLGS GEGMAVSHRN NSGMLPPGSL LRNSQVWLGR HNLFEPEDTG RRVPVSHSFP HPLYNMSLLK HQSLRPDEDS SHDLMLLRLS EPAKITDVVK VLGLPTQEPA LGTTCYASGW GSIEPEEFLR PRSLQCVSLH LLSNDMCARA YSEKVTEFML CAGLWTGGKD TCGGDSGGPL VCNGVLQGIT SWGPEPCALP EKPAVYTKVV HYRKWIKDTI AANP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.