Details for: MEP1A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: precursor cell (CL0011115)
Fold Change: 5.9534
Cell Significance Index: 45.1500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 5.0049
Cell Significance Index: 108.4300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 4.2886
Cell Significance Index: 64.2600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 3.8598
Cell Significance Index: -2.5900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 2.1131
Cell Significance Index: 51.1900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 1.8963
Cell Significance Index: -5.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.8439
Cell Significance Index: 83.5800 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.4810
Cell Significance Index: 24.9100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.4784
Cell Significance Index: 240.4400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.3433
Cell Significance Index: 146.1200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2253
Cell Significance Index: 1106.3200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.1894
Cell Significance Index: 25.3300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.0837
Cell Significance Index: 22.4800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.0142
Cell Significance Index: 29.2200 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.9218
Cell Significance Index: 11.6500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.8540
Cell Significance Index: 59.0600 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.4862
Cell Significance Index: 4.9100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4349
Cell Significance Index: 43.0200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.3880
Cell Significance Index: 9.7000 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.3748
Cell Significance Index: 3.8800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3547
Cell Significance Index: 12.4700 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.3437
Cell Significance Index: 5.0100 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.2842
Cell Significance Index: 3.0800 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.2205
Cell Significance Index: 2.7700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2092
Cell Significance Index: 41.5200 - Cell Name: stem cell (CL0000034)
Fold Change: 0.2078
Cell Significance Index: 1.5100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.1841
Cell Significance Index: 3.9400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1717
Cell Significance Index: 5.5000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0958
Cell Significance Index: 11.1700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0914
Cell Significance Index: 17.4000 - Cell Name: enterocyte (CL0000584)
Fold Change: 0.0806
Cell Significance Index: 0.5000 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 0.0279
Cell Significance Index: 0.4600 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0265
Cell Significance Index: 0.6600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0005
Cell Significance Index: 0.0800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0004
Cell Significance Index: 0.1400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0001
Cell Significance Index: 0.0100 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0008
Cell Significance Index: -1.5400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0008
Cell Significance Index: -1.4900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0008
Cell Significance Index: -1.2800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0011
Cell Significance Index: -1.4900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0019
Cell Significance Index: -1.3800 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: -0.0023
Cell Significance Index: -0.0200 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0024
Cell Significance Index: -1.3200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0025
Cell Significance Index: -1.9300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0029
Cell Significance Index: -0.5800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0037
Cell Significance Index: -2.0800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0063
Cell Significance Index: -2.8500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0066
Cell Significance Index: -4.2100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0106
Cell Significance Index: -2.2300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0107
Cell Significance Index: -0.5400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0133
Cell Significance Index: -1.8300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0148
Cell Significance Index: -4.2500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0153
Cell Significance Index: -0.2300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0159
Cell Significance Index: -0.4100 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0161
Cell Significance Index: -0.1700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0166
Cell Significance Index: -0.6800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0168
Cell Significance Index: -0.2400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0186
Cell Significance Index: -1.9400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0204
Cell Significance Index: -1.2500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0205
Cell Significance Index: -3.7000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0206
Cell Significance Index: -0.3500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0226
Cell Significance Index: -2.3100 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.0245
Cell Significance Index: -0.2600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0262
Cell Significance Index: -1.3600 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0275
Cell Significance Index: -0.6900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0280
Cell Significance Index: -4.0700 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.0282
Cell Significance Index: -0.4300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0287
Cell Significance Index: -0.7800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0302
Cell Significance Index: -2.0300 - Cell Name: goblet cell (CL0000160)
Fold Change: -0.0310
Cell Significance Index: -0.2800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0340
Cell Significance Index: -2.6100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0344
Cell Significance Index: -4.2300 - Cell Name: urothelial cell (CL0000731)
Fold Change: -0.0445
Cell Significance Index: -0.3100 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.0476
Cell Significance Index: -0.6100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0509
Cell Significance Index: -1.8700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0526
Cell Significance Index: -2.9500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0528
Cell Significance Index: -1.8500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0533
Cell Significance Index: -1.0400 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0537
Cell Significance Index: -0.5900 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0541
Cell Significance Index: -1.7100 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0589
Cell Significance Index: -0.4800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0592
Cell Significance Index: -3.6400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0602
Cell Significance Index: -1.9700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0606
Cell Significance Index: -1.9300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0610
Cell Significance Index: -2.7000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0612
Cell Significance Index: -1.6400 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.0614
Cell Significance Index: -0.4000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0614
Cell Significance Index: -1.0400 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.0633
Cell Significance Index: -0.3300 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0642
Cell Significance Index: -1.8900 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0652
Cell Significance Index: -0.8700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0652
Cell Significance Index: -1.5900 - Cell Name: peptic cell (CL0000155)
Fold Change: -0.0653
Cell Significance Index: -0.5800 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0661
Cell Significance Index: -1.3500 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.0662
Cell Significance Index: -0.5700 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.0671
Cell Significance Index: -0.7400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0708
Cell Significance Index: -2.6800 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: -0.0737
Cell Significance Index: -0.5800 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0738
Cell Significance Index: -1.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1536731567
Symbol: MEP1A_HUMAN
Name: Meprin A subunit alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8262185
Title: Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells.
PubMed ID: 8262185
PubMed ID: 17976009
Title: Human and mouse homo-oligomeric meprin A metalloendopeptidase: substrate and inhibitor specificities.
PubMed ID: 17976009
DOI: 10.1515/bc.2007.156
PubMed ID: 27399812
Title: SweetNET: A Bioinformatics Workflow for Glycopeptide MS/MS Spectral Analysis.
PubMed ID: 27399812
Sequence Information:
- Length: 746
- Mass: 84419
- Checksum: B5F0812F2850F958
- Sequence:
MAWIRSTCIL FFTLLFAHIA AVPIKYLPEE NVHDADFGEQ KDISEINLAA GLDLFQGDIL LQKSRNGLRD PNTRWTFPIP YILADNLGLN AKGAILYAFE MFRLKSCVDF KPYEGESSYI IFQQFDGCWS EVGDQHVGQN ISIGQGCAYK AIIEHEILHA LGFYHEQSRT DRDDYVNIWW DQILSGYQHN FDTYDDSLIT DLNTPYDYES LMHYQPFSFN KNASVPTITA KIPEFNSIIG QRLDFSAIDL ERLNRMYNCT TTHTLLDHCT FEKANICGMI QGTRDDTDWA HQDSAQAGEV DHTLLGQCTG AGYFMQFSTS SGSAEEAALL ESRILYPKRK QQCLQFFYKM TGSPSDRLVV WVRRDDSTGN VRKLVKVQTF QGDDDHNWKI AHVVLKEEQK FRYLFQGTKG DPQNSTGGIY LDDITLTETP CPTGVWTVRN FSQVLENTSK GDKLQSPRFY NSEGYGFGVT LYPNSRESSG YLRLAFHVCS GENDAILEWP VENRQVIITI LDQEPDVRNR MSSSMVFTTS KSHTSPAIND TVIWDRPSRV GTYHTDCNCF RSIDLGWSGF ISHQMLKRRS FLKNDDLIIF VDFEDITHLS QTEVPTKGKR LSPQGLILQG QEQQVSEEGS GKAMLEEALP VSLSQGQPSR QKRSVENTGP LEDHNWPQYF RDPCDPNPCQ NDGICVNVKG MASCRCISGH AFFYTGERCQ AVQVHGSVLG MVIGGTAGVI FLTFSIIAIL SQRPRK
Genular Protein ID: 404183028
Symbol: B7ZL91_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 774
- Mass: 87897
- Checksum: 3BF8DE8342E89C99
- Sequence:
MAWIRSTCIL FFTLLFAHIA AVPVSRVLLF GYLEILILVY IIHFLYIYFF QIKYLPEENV HDADFGEQKD ISEINLAAGL DLFQGDILLQ KSRNGLRDPN TRWTFPIPYI LADNLGLNAK GAILYAFEMF RLKSCVDFKP YEGESSYIIF QQFDGCWSEV GDQHVGQNIS IGQGCAYKAI IEHEILHALG FYHEQSRTDR DDYVNIWWDQ ILSGYQHNFD TYDDSLITDL NTPYDYESLM HYQPFSFNKN ASVPTITAKI PEFNSIIGQR LDFSAIDLER LNRMYNCTTT HTLLDHCTFE KANICGMIQG TRDDTDWAHQ DSAQAGEVDH TLLGQCTGAG YFMQFSTSSG SAEEAALLES RILYPKRKQQ CLQFFYKMTG SPSDRLVVWV RRDDSTGNVR KLVKVQTFQG DDDHNWKIAH VVLKEEQKFR YLFQGTKGDP QNSTGGIYLD DITLTETPCP TGVWTVRNFS QVLENTSKGD KLQSPRFYNS EGYGFGVTLY PNSRESSGYL RLAFHVCSGE NDAILEWPVE NRQVIITILD QEPDVRNRMS SSMVFTTSKS HTSPAINDTV IWDRPSRVGT YHTDCNCFRS IDLGWSGFIS HQMLKRRSFL KNDDLIIFVD FEDITHLSQT EVPTKGKRLS PQGLILQGQE QQVSEEGSGK AMLEEALPVS LSQGQPSRQK RSVENTGPLE DHNWPQYFRD PCDPNPCQND GICVNVKGMA SCRCISGHAF FYTGERCQAV QVHGSVLGMV IGGTAGVIFL TFSIIAILSQ RPRK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.