Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 23.4016
Cell Significance Index: -3.6400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 14.4297
Cell Significance Index: -3.6600 - Cell Name: centroblast (CL0009112)
Fold Change: 8.2552
Cell Significance Index: 19.2600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 3.1069
Cell Significance Index: 200.4400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 2.9604
Cell Significance Index: -3.6500 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 2.4687
Cell Significance Index: 11.0400 - Cell Name: centrocyte (CL0009111)
Fold Change: 1.7952
Cell Significance Index: 5.5400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.7820
Cell Significance Index: 210.1500 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.3476
Cell Significance Index: 20.8500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 0.9452
Cell Significance Index: -3.7300 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.4139
Cell Significance Index: 2.5000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.1913
Cell Significance Index: 4.7700 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 0.1707
Cell Significance Index: 1.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1325
Cell Significance Index: 2.2700 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.1015
Cell Significance Index: 1.0300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0871
Cell Significance Index: 5.4900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0449
Cell Significance Index: 9.0100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0314
Cell Significance Index: 6.2400 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 0.0235
Cell Significance Index: 0.1500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0126
Cell Significance Index: 4.5200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0005
Cell Significance Index: 0.8500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0007
Cell Significance Index: -0.0100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0008
Cell Significance Index: -1.2000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0013
Cell Significance Index: -2.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0019
Cell Significance Index: -2.6400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0051
Cell Significance Index: -3.8500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0054
Cell Significance Index: -3.4500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0059
Cell Significance Index: -1.7000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0060
Cell Significance Index: -4.4300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0069
Cell Significance Index: -4.3200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0076
Cell Significance Index: -4.2800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0077
Cell Significance Index: -3.5100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0116
Cell Significance Index: -0.6500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0157
Cell Significance Index: -2.2800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0159
Cell Significance Index: -2.8700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0184
Cell Significance Index: -3.1400 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0197
Cell Significance Index: -0.2500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0222
Cell Significance Index: -4.6800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0288
Cell Significance Index: -3.5400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0296
Cell Significance Index: -1.3800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0307
Cell Significance Index: -3.5800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0330
Cell Significance Index: -3.4400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0379
Cell Significance Index: -1.0600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0395
Cell Significance Index: -4.5200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0416
Cell Significance Index: -2.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0446
Cell Significance Index: -4.5600 - Cell Name: memory B cell (CL0000787)
Fold Change: -0.0470
Cell Significance Index: -0.5000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0470
Cell Significance Index: -3.6100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.0482
Cell Significance Index: -0.8900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0490
Cell Significance Index: -1.3100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0564
Cell Significance Index: -1.4500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0565
Cell Significance Index: -3.4700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0574
Cell Significance Index: -2.5400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0577
Cell Significance Index: -1.8900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0582
Cell Significance Index: -2.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0611
Cell Significance Index: -1.9500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0622
Cell Significance Index: -1.2900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0668
Cell Significance Index: -2.5300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0682
Cell Significance Index: -4.1800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0698
Cell Significance Index: -1.9000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0708
Cell Significance Index: -2.4800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0735
Cell Significance Index: -3.8200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0829
Cell Significance Index: -1.7600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0859
Cell Significance Index: -3.0200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0869
Cell Significance Index: -4.0900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0907
Cell Significance Index: -1.7700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0935
Cell Significance Index: -4.8700 - Cell Name: naive B cell (CL0000788)
Fold Change: -0.0978
Cell Significance Index: -1.0300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1034
Cell Significance Index: -2.5800 - Cell Name: late promyelocyte (CL0002151)
Fold Change: -0.1108
Cell Significance Index: -0.7400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1125
Cell Significance Index: -3.2100 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1151
Cell Significance Index: -2.3100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1160
Cell Significance Index: -2.5400 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -0.1180
Cell Significance Index: -1.4600 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.1193
Cell Significance Index: -1.1800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1193
Cell Significance Index: -4.3800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1201
Cell Significance Index: -3.4600 - Cell Name: B cell (CL0000236)
Fold Change: -0.1219
Cell Significance Index: -1.4400 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1227
Cell Significance Index: -2.6500 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.1233
Cell Significance Index: -1.7900 - Cell Name: B-1b B cell (CL0000821)
Fold Change: -0.1256
Cell Significance Index: -0.6300 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1258
Cell Significance Index: -3.9800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1278
Cell Significance Index: -5.5600 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: -0.1285
Cell Significance Index: -1.2300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1364
Cell Significance Index: -5.5900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1380
Cell Significance Index: -2.8800 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.1385
Cell Significance Index: -1.9700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1389
Cell Significance Index: -7.0200 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1401
Cell Significance Index: -2.7700 - Cell Name: ionocyte (CL0005006)
Fold Change: -0.1416
Cell Significance Index: -1.4800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1434
Cell Significance Index: -3.7700 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1435
Cell Significance Index: -2.9200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1448
Cell Significance Index: -3.7000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1483
Cell Significance Index: -3.9600 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.1484
Cell Significance Index: -1.9200 - Cell Name: mature B cell (CL0000785)
Fold Change: -0.1490
Cell Significance Index: -0.9700 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1504
Cell Significance Index: -2.5300 - Cell Name: follicular B cell (CL0000843)
Fold Change: -0.1559
Cell Significance Index: -0.7800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1579
Cell Significance Index: -4.2300 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.1588
Cell Significance Index: -3.1300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1316240067
Symbol: PAX5_HUMAN
Name: Paired box protein Pax-5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1516825
Title: Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
PubMed ID: 1516825
DOI: 10.1101/gad.6.9.1589
PubMed ID: 15385562
Title: Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells.
PubMed ID: 15385562
PubMed ID: 19725825
Title: Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells.
PubMed ID: 19725825
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 17344859
Title: Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
PubMed ID: 17344859
DOI: 10.1038/nature05690
PubMed ID: 9742255
Title: Isolation of genes negatively or positively co-expressed with human recombination activating gene 1 (RAG1) by differential display PCR (DD RT-PCR).
PubMed ID: 9742255
PubMed ID: 10197586
Title: The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins.
PubMed ID: 10197586
PubMed ID: 10811620
Title: Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family.
PubMed ID: 10811620
PubMed ID: 23678172
Title: The B-cell-specific transcription factor and master regulator Pax5 promotes Epstein-Barr virus latency by negatively regulating the viral immediate early protein BZLF1.
PubMed ID: 23678172
DOI: 10.1128/jvi.00546-13
PubMed ID: 27181361
Title: PAX5 tyrosine phosphorylation by SYK co-operatively functions with its serine phosphorylation to cancel the PAX5-dependent repression of BLIMP1: A mechanism for antigen-triggered plasma cell differentiation.
PubMed ID: 27181361
PubMed ID: 31941781
Title: B Cell-Specific Transcription Activator PAX5 Recruits p300 To Support EBNA1-Driven Transcription.
PubMed ID: 31941781
DOI: 10.1128/jvi.02028-19
PubMed ID: 32612238
Title: Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion.
PubMed ID: 32612238
PubMed ID: 11779502
Title: Structural studies of Ets-1/Pax5 complex formation on DNA.
PubMed ID: 11779502
PubMed ID: 24013638
Title: A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.
PubMed ID: 24013638
DOI: 10.1038/ng.2754
Sequence Information:
- Length: 391
- Mass: 42149
- Checksum: DB37E6EACD9F993A
- Sequence:
MDLEKNYPTP RTSRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR PCDISRQLRV SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA EYKRQNPTMF AWEIRDRLLA ERVCDNDTVP SVSSINRIIR TKVQQPPNQP VPASSHSIVS TGSVTQVSSV STDSAGSSYS ISGILGITSP SADTNKRKRD EGIQESPVPN GHSLPGRDFL RKQMRGDLFT QQQLEVLDRV FERQHYSDIF TTTEPIKPEQ TTEYSAMASL AGGLDDMKAN LASPTPADIG SSVPGPQSYP IVTGRDLAST TLPGYPPHVP PAGQGSYSAP TLTGMVPGSE FSGSPYSHPQ YSSYNDSWRF PNPGLLGSPY YYSAAARGAA PPAAATAYDR H
Genular Protein ID: 3134212579
Symbol: E7EQT0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 324
- Mass: 35269
- Checksum: 58AE4FF245B8B979
- Sequence:
MDLEKNYPTP RTSRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR PCDISRQLRV SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA EYKRQNPTMF AWEIRDRLLA ERVCDNDTVP SVSSINRIIR TKVQQPPNQP VPASSHSIVS TGSVTQVSSV STDSAGSSYS ISGILGITSP SADTNKRKRD EGIQESPVPN GHSLPGRDFL RKQMRGDLFT QQQLEVLDRV FERQHYSDIF TTTEPIKPEQ GVSFPGVPTA TLSIPRTTTP GGSPTRGCLA PPTIIALPPE EPPHLQPPLP MTVTDPWSQA GTKH
Genular Protein ID: 2576143406
Symbol: E7ES87_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 220
- Mass: 23685
- Checksum: 74A33883A0719337
- Sequence:
MFAWEIRDRL LAERVCDNDT VPSVSSINRI IRTKVQQPPN QPVPASSHSI VSTGSVTQVS SVSTDSAGSS YSISGILGIT SPSADTNKRK RDEGIQESPV PNGHSLPGRD FLRKQMRGDL FTQQQLEVLD RVFERQHYSD IFTTTEPIKP EQTTEYSAMA SLAGGLDDMK ANLASPTPAD IGSSVPGPQS YPIVTGSPYY YSAAARGAAP PAAATAYDRH
Genular Protein ID: 3982866983
Symbol: E7ERK2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 283
- Mass: 30321
- Checksum: 20828150572E66D5
- Sequence:
MFAWEIRDRL LAERVCDNDT VPSVSSINRI IRTKVQQPPN QPVPASSHSI VSTGSVTQVS SVSTDSAGSS YSISGILGIT SPSADTNKRK RDEGIQESPV PNGHSLPGRD FLRKQMRGDL FTQQQLEVLD RVFERQHYSD IFTTTEPIKP EQTTEYSAMA SLAGGLDDMK ANLASPTPAD IGSSVPGPQS YPIVTGRDLA STTLPGYPPH VPPAGQGSYS APTLTGMVPG SEFSGSPYSH PQYSSYNDSW RFPNPGLLGS PYYYSAAARG AAPPAAATAY DRH
Genular Protein ID: 420880688
Symbol: C0KTE5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19725825
Title: Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells.
PubMed ID: 19725825
Sequence Information:
- Length: 136
- Mass: 14857
- Checksum: 1429D7ED040BFD00
- Sequence:
DTNKRKRDEG IQESPVPNGH SLPGRDFLRK QMRGDLFTQQ QLEVLDRVFE RQHYSDIFTT TEPIKPEQTT EYSAMASLAG GLDDMKANLA SPTPADIGSS VPGPQSYPIV TGSPYYYSAA ARGAAPPAAA TAYDRH
Genular Protein ID: 1119517879
Symbol: E7ERW5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 295
- Mass: 32459
- Checksum: 7BE055066EE14208
- Sequence:
MDLEKNYPTP RTSRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR PCDISRQLRV SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA EYKRQNPTMF AWEIRDRLLA ERVCDNDTVP SVSSINRIIR TKVQQPPNQP VPASSHSIVS TGSVTQVSSV STDSAGSSYS ISGILGITSP SADTNKRKRD EGIQESPVPN GHSLPGRDFL RKQMRGDLFT QQQLEVLDRV FERQHYSDIF TTTEPIKPEQ APPTIIALPP EEPPHLQPPL PMTVTDPWSQ AGTKH
Genular Protein ID: 612080779
Symbol: C0KTF5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19725825
Title: Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells.
PubMed ID: 19725825
Sequence Information:
- Length: 26
- Mass: 2939
- Checksum: 2A72F22CE9512382
- Sequence:
MDLEKNYPTP RTSRTGIMRQ EASSLG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.