Details for: RBP3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 9.9520
Cell Significance Index: 627.2400 - Cell Name: macroglial cell (CL0000126)
Fold Change: 4.5300
Cell Significance Index: 52.4500 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 1.7009
Cell Significance Index: 13.1100 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 1.2289
Cell Significance Index: 10.8300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8077
Cell Significance Index: 11.0200 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.5263
Cell Significance Index: 6.3800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.2047
Cell Significance Index: 23.4500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1216
Cell Significance Index: 1.4500 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.0577
Cell Significance Index: 0.9700 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 0.0096
Cell Significance Index: 0.1200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0092
Cell Significance Index: 1.6600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0032
Cell Significance Index: -6.0600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0086
Cell Significance Index: -5.4600 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0120
Cell Significance Index: -0.2000 - Cell Name: Mueller cell (CL0000636)
Fold Change: -0.0208
Cell Significance Index: -0.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0281
Cell Significance Index: -15.8500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0313
Cell Significance Index: -6.2800 - Cell Name: pancreatic epsilon cell (CL0005019)
Fold Change: -0.0327
Cell Significance Index: -0.3000 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0371
Cell Significance Index: -0.4100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0378
Cell Significance Index: -5.4900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0380
Cell Significance Index: -2.1300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0533
Cell Significance Index: -2.7700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0544
Cell Significance Index: -2.8600 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: -0.0673
Cell Significance Index: -0.7600 - Cell Name: pulmonary alveolar type 1 cell (CL0002062)
Fold Change: -0.0766
Cell Significance Index: -0.8400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0808
Cell Significance Index: -5.4400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0903
Cell Significance Index: -5.5500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0961
Cell Significance Index: -4.2500 - Cell Name: neural cell (CL0002319)
Fold Change: -0.1029
Cell Significance Index: -1.2000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1074
Cell Significance Index: -6.5800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1105
Cell Significance Index: -5.7600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1125
Cell Significance Index: -4.2600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1198
Cell Significance Index: -3.2000 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.1504
Cell Significance Index: -3.0000 - Cell Name: neuron (CL0000540)
Fold Change: -0.1604
Cell Significance Index: -1.5200 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1696
Cell Significance Index: -4.3200 - Cell Name: retinal astrocyte (CL4033015)
Fold Change: -0.1706
Cell Significance Index: -1.6700 - Cell Name: differentiation-committed oligodendrocyte precursor (CL4023059)
Fold Change: -0.1770
Cell Significance Index: -2.1000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.1790
Cell Significance Index: -2.2200 - Cell Name: stromal cell (CL0000499)
Fold Change: -0.1840
Cell Significance Index: -1.8800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1868
Cell Significance Index: -6.5500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1948
Cell Significance Index: -2.7900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2019
Cell Significance Index: -6.6100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2036
Cell Significance Index: -5.8100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2055
Cell Significance Index: -6.5500 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.2235
Cell Significance Index: -3.1000 - Cell Name: diffuse bipolar 2 cell (CL4033028)
Fold Change: -0.2320
Cell Significance Index: -2.8500 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.2336
Cell Significance Index: -3.1500 - Cell Name: adipocyte (CL0000136)
Fold Change: -0.2363
Cell Significance Index: -3.1500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2454
Cell Significance Index: -5.8900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2499
Cell Significance Index: -4.2100 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: -0.2565
Cell Significance Index: -3.1200 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: -0.2582
Cell Significance Index: -3.2400 - Cell Name: invaginating midget bipolar cell (CL4033034)
Fold Change: -0.2593
Cell Significance Index: -3.2000 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.2630
Cell Significance Index: -3.4400 - Cell Name: mural cell (CL0008034)
Fold Change: -0.2678
Cell Significance Index: -3.2600 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: -0.2723
Cell Significance Index: -3.7400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2726
Cell Significance Index: -6.8000 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.2738
Cell Significance Index: -2.2600 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: -0.2756
Cell Significance Index: -3.1600 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: -0.2799
Cell Significance Index: -3.2500 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.2840
Cell Significance Index: -4.3200 - Cell Name: podocyte (CL0000653)
Fold Change: -0.2842
Cell Significance Index: -3.2600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.2922
Cell Significance Index: -4.1600 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: -0.2998
Cell Significance Index: -3.1500 - Cell Name: diffuse bipolar 3b cell (CL4033030)
Fold Change: -0.3058
Cell Significance Index: -3.6900 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.3073
Cell Significance Index: -3.9700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3096
Cell Significance Index: -6.6900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.3097
Cell Significance Index: -5.7300 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: -0.3099
Cell Significance Index: -3.2600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3138
Cell Significance Index: -6.6600 - Cell Name: flat midget bipolar cell (CL4033033)
Fold Change: -0.3138
Cell Significance Index: -3.9000 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.3238
Cell Significance Index: -6.3300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3240
Cell Significance Index: -6.5100 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.3243
Cell Significance Index: -4.1100 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3301
Cell Significance Index: -6.8900 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: -0.3334
Cell Significance Index: -4.0300 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.3339
Cell Significance Index: -4.3200 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3351
Cell Significance Index: -6.6300 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: -0.3365
Cell Significance Index: -3.2100 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.3430
Cell Significance Index: -6.7500 - Cell Name: amacrine cell (CL0000561)
Fold Change: -0.3521
Cell Significance Index: -4.4100 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: -0.3635
Cell Significance Index: -3.7600 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.3673
Cell Significance Index: -4.5800 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3716
Cell Significance Index: -4.6900 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: -0.3721
Cell Significance Index: -4.1200 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: -0.3732
Cell Significance Index: -4.4100 - Cell Name: pro-B cell (CL0000826)
Fold Change: -0.3739
Cell Significance Index: -4.0200 - Cell Name: macrophage (CL0000235)
Fold Change: -0.3776
Cell Significance Index: -3.8600 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.3818
Cell Significance Index: -4.1600 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: -0.3873
Cell Significance Index: -4.0600 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: -0.3885
Cell Significance Index: -4.2500 - Cell Name: myelocyte (CL0002193)
Fold Change: -0.3968
Cell Significance Index: -4.2400 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.3984
Cell Significance Index: -4.1100 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3985
Cell Significance Index: -6.8900 - Cell Name: T cell (CL0000084)
Fold Change: -0.4015
Cell Significance Index: -4.7400 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: -0.4016
Cell Significance Index: -3.8600 - Cell Name: basal cell (CL0000646)
Fold Change: -0.4025
Cell Significance Index: -4.7900 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: -0.4086
Cell Significance Index: -3.5200 - Cell Name: myeloid cell (CL0000763)
Fold Change: -0.4116
Cell Significance Index: -5.4700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 605132852
Symbol: RET3_HUMAN
Name: Retinol-binding protein 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2542268
Title: Human interstitial retinoid-binding protein. Gene structure and primary structure.
PubMed ID: 2542268
PubMed ID: 2303470
Title: Characterization and comparative structural features of the gene for human interstitial retinol-binding protein.
PubMed ID: 2303470
PubMed ID: 2792773
Title: Cloning of cDNAs encoding human interphotoreceptor retinoid-binding protein (IRBP) and comparison with bovine IRBP sequences.
PubMed ID: 2792773
PubMed ID: 3170584
Title: Internal quadruplication in the structure of human interstitial retinol-binding protein deduced from its cloned cDNA.
PubMed ID: 3170584
PubMed ID: 21697133
Title: Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.
PubMed ID: 21697133
DOI: 10.1167/iovs.11-7479
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3455009
Title: Human interstitial retinol-binding protein (IRBP): cloning, partial sequence, and chromosomal localization.
PubMed ID: 3455009
DOI: 10.1007/bf01534925
PubMed ID: 2402443
Title: Hypomethylation of the interphotoreceptor retinoid-binding protein (IRBP) promotor and first exon is linked to expression of the gene.
PubMed ID: 2402443
PubMed ID: 17286855
Title: Mapping of transcription start sites of human retina expressed genes.
PubMed ID: 17286855
PubMed ID: 3827838
Title: Interspecies conservation of structure of interphotoreceptor retinoid-binding protein. Similarities and differences as adjudged by peptide mapping and N-terminal sequencing.
PubMed ID: 3827838
DOI: 10.1042/bj2400019
PubMed ID: 3743780
Title: N-terminal sequence homologies in interstitial retinol-binding proteins from 10 vertebrate species.
PubMed ID: 3743780
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 19074801
Title: A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa.
PubMed ID: 19074801
DOI: 10.1167/iovs.08-2497
PubMed ID: 23486466
Title: Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP).
PubMed ID: 23486466
Sequence Information:
- Length: 1247
- Mass: 135363
- Checksum: 6C1841411E012E0F
- Sequence:
MMREWVLLMS VLLCGLAGPT HLFQPSLVLD MAKVLLDNYC FPENLLGMQE AIQQAIKSHE ILSISDPQTL ASVLTAGVQS SLNDPRLVIS YEPSTPEPPP QVPALTSLSE EELLAWLQRG LRHEVLEGNV GYLRVDSVPG QEVLSMMGEF LVAHVWGNLM GTSALVLDLR HCTGGQVSGI PYIISYLHPG NTILHVDTIY NRPSNTTTEI WTLPQVLGER YGADKDVVVL TSSQTRGVAE DIAHILKQMR RAIVVGERTG GGALDLRKLR IGESDFFFTV PVSRSLGPLG GGSQTWEGSG VLPCVGTPAE QALEKALAIL TLRSALPGVV HCLQEVLKDY YTLVDRVPTL LQHLASMDFS TVVSEEDLVT KLNAGLQAAS EDPRLLVRAI GPTETPSWPA PDAAAEDSPG VAPELPEDEA IRQALVDSVF QVSVLPGNVG YLRFDSFADA SVLGVLAPYV LRQVWEPLQD TEHLIMDLRH NPGGPSSAVP LLLSYFQGPE AGPVHLFTTY DRRTNITQEH FSHMELPGPR YSTQRGVYLL TSHRTATAAE EFAFLMQSLG WATLVGEITA GNLLHTRTVP LLDTPEGSLA LTVPVLTFID NHGEAWLGGG VVPDAIVLAE EALDKAQEVL EFHQSLGALV EGTGHLLEAH YARPEVVGQT SALLRAKLAQ GAYRTAVDLE SLASQLTADL QEVSGDHRLL VFHSPGELVV EEAPPPPPAV PSPEELTYLI EALFKTEVLP GQLGYLRFDA MAELETVKAV GPQLVRLVWQ QLVDTAALVI DLRYNPGSYS TAIPLLCSYF FEAEPRQHLY SVFDRATSKV TEVWTLPQVA GQRYGSHKDL YILMSHTSGS AAEAFAHTMQ DLQRATVIGE PTAGGALSVG IYQVGSSPLY ASMPTQMAMS ATTGKAWDLA GVEPDITVPM SEALSIAQDI VALRAKVPTV LQTAGKLVAD NYASAELGAK MATKLSGLQS RYSRVTSEVA LAEILGADLQ MLSGDPHLKA AHIPENAKDR IPGIVPMQIP SPEVFEELIK FSFHTNVLED NIGYLRFDMF GDGELLTQVS RLLVEHIWKK IMHTDAMIID MRFNIGGPTS SIPILCSYFF DEGPPVLLDK IYSRPDDSVS ELWTHAQVVG ERYGSKKSMV ILTSSVTAGT AEEFTYIMKR LGRALVIGEV TSGGCQPPQT YHVDDTNLYL TIPTARSVGA SDGSSWEGVG VTPHVVVPAE EALARAKEML QHNQLRVKRS PGLQDHL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.