No CSI details found for gene ID: 6755
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1760088671
Symbol: SSR5_HUMAN
Name: Somatostatin receptor type 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7908405
Title: Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28.
PubMed ID: 7908405
PubMed ID: 8373420
Title: Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype.
PubMed ID: 8373420
PubMed ID: 8078491
Title: Characterization of cloned human somatostatin receptor SSTR5.
PubMed ID: 8078491
PubMed ID: 12072395
Title: Identification of an upstream pituitary-active promoter of human somatostatin receptor subtype 5.
PubMed ID: 12072395
PubMed ID: 11157797
Title: Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.
PubMed ID: 11157797
DOI: 10.1093/hmg/10.4.339
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 18653781
Title: Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization.
PubMed ID: 18653781
DOI: 10.1210/me.2007-0334
PubMed ID: 21820437
Title: Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase.
PubMed ID: 21820437
Sequence Information:
- Length: 364
- Mass: 39202
- Checksum: 905744715F31121C
- Sequence:
MEPLFPASTP SWNASSPGAA SGGGDNRTLV GPAPSAGARA VLVPVLYLLV CAAGLGGNTL VIYVVLRFAK MKTVTNIYIL NLAVADVLYM LGLPFLATQN AASFWPFGPV LCRLVMTLDG VNQFTSVFCL TVMSVDRYLA VVHPLSSARW RRPRVAKLAS AAAWVLSLCM SLPLLVFADV QEGGTCNASW PEPVGLWGAV FIIYTAVLGF FAPLLVICLC YLLIVVKVRA AGVRVGCVRR RSERKVTRMV LVVVLVFAGC WLPFFTVNIV NLAVALPQEP ASAGLYFFVV ILSYANSCAN PVLYGFLSDN FRQSFQKVLC LRKGSGAKDA DATEPRPDRI RQQQEATPPA HRAAANGLMQ TSKL
Details Unavailable
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{
"geneID": 6755,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AC009041.10"
]
},
"genePos": {
"start": 4992,
"end": 13699
},
"orientation": true,
"symbol": "SSTR5",
"created": {
"$date": {
"$numberLong": "1738333349190"
}
},
"crossReference": {
"enseGeneID": "ENSG00000162009",
"enseRnaID": [
"ENST00000293897.7"
],
"enseProtID": [
"ENSP00000293897.4"
]
},
"chrom": {
"pos": "16",
"type": 1,
"loc": "16p13.3"
},
"desc": "somatostatin receptor 5",
"geneType": 5,
"mim": [
{
"id": 182455,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-162582",
"term": "Signal Transduction",
"cat": 10
},
{
"id": "R-HSA-372790",
"term": "Signaling by GPCR",
"cat": 11
},
{
"id": "R-HSA-388396",
"term": "GPCR downstream signalling",
"cat": 12
},
{
"id": "R-HSA-500792",
"term": "GPCR ligand binding",
"cat": 12
},
{
"id": "R-HSA-373076",
"term": "Class A\/1 (Rhodopsin-like receptors)",
"cat": 13
},
{
"id": "R-HSA-418594",
"term": "G alpha (i) signalling events",
"cat": 13
},
{
"id": "R-HSA-375276",
"term": "Peptide ligand-binding receptors",
"cat": 14
},
{
"id": "GO:0004994",
"term": "somatostatin receptor activity",
"cat": 0
},
{
"id": "GO:0005515",
"term": "protein binding",
"pubMed": [
15247250,
18653781,
19426801
],
"cat": 0
},
{
"id": "GO:0042923",
"term": "neuropeptide binding",
"cat": 0
},
{
"id": "GO:0007186",
"term": "G protein-coupled receptor signaling pathway",
"pubMed": [
9892014
],
"cat": 1
},
{
"id": "GO:0007187",
"term": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger",
"cat": 1
},
{
"id": "GO:0007218",
"term": "neuropeptide signaling pathway",
"cat": 1
},
{
"id": "GO:0008285",
"term": "negative regulation of cell population proliferation",
"cat": 1
},
{
"id": "GO:0032467",
"term": "positive regulation of cytokinesis",
"pubMed": [
22888021
],
"cat": 1
},
{
"id": "GO:0038170",
"term": "somatostatin signaling pathway",
"cat": 1
},
{
"id": "GO:0050796",
"term": "regulation of insulin secretion",
"cat": 1
},
{
"id": "GO:0071385",
"term": "cellular response to glucocorticoid stimulus",
"cat": 1
},
{
"id": "GO:0005886",
"term": "plasma membrane",
"cat": 2
},
{
"id": "GO:0043005",
"term": "neuron projection",
"cat": 2
}
],
"protein": [
{
"symbol": "SSR5_HUMAN",
"name": "Somatostatin receptor type 5",
"accession": [
"P35346",
"P34988",
"Q541E0",
"Q9UJI5"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"L14865",
"D16827",
"AY081193",
"AE006466",
"AL031713",
"CH471112"
],
"CCDS": [
"CCDS10429.1"
],
"PIR": [
"I57955",
"JN0763"
],
"RefSeq": [
"NP_001044.1",
"NP_001166031.1"
],
"PDB": [
"8X8L",
"8X8N"
],
"PDBsum": [
"8X8L",
"8X8N"
],
"AlphaFoldDB": [
"P35346"
],
"EMDB": [
"EMD-38148",
"EMD-38150"
],
"SMR": [
"P35346"
],
"BioGRID": [
"112633"
],
"CORUM": [
"P35346"
],
"IntAct": [
"P35346"
],
"STRING": [
"9606.ENSP00000293897"
],
"BindingDB": [
"P35346"
],
"ChEMBL": [
"CHEMBL1792"
],
"DrugBank": [
"DB15494",
"DB06791",
"DB13985",
"DB06663",
"DB09099",
"DB04894"
],
"DrugCentral": [
"P35346"
],
"GuidetoPHARMACOLOGY": [
"359"
],
"GlyCosmos": [
"P35346"
],
"GlyGen": [
"P35346"
],
"iPTMnet": [
"P35346"
],
"PhosphoSitePlus": [
"P35346"
],
"BioMuta": [
"SSTR5"
],
"DMDM": [
"12644225"
],
"jPOST": [
"P35346"
],
"PaxDb": [
"9606-ENSP00000293897"
],
"PeptideAtlas": [
"P35346"
],
"ProteomicsDB": [
"55025"
],
"Antibodypedia": [
"3358"
],
"DNASU": [
"6755"
],
"Ensembl": [
"ENST00000293897.7",
"ENST00000689027.1",
"ENST00000711615.1"
],
"KEGG": [
"hsa:6755"
],
"MANE-Select": [
"ENST00000689027.1"
],
"UCSC": [
"uc002ckq.4"
],
"AGR": [
"HGNC:11334"
],
"CTD": [
"6755"
],
"DisGeNET": [
"6755"
],
"GeneCards": [
"SSTR5"
],
"HGNC": [
"HGNC:11334"
],
"HPA": [
"ENSG00000162009"
],
"MIM": [
"182455"
],
"neXtProt": [
"NX_P35346"
],
"OpenTargets": [
"ENSG00000162009"
],
"PharmGKB": [
"PA36158"
],
"VEuPathDB": [
"HostDB:ENSG00000162009"
],
"eggNOG": [
"KOG3656"
],
"GeneTree": [
"ENSGT00940000160265"
],
"HOGENOM": [
"CLU_009579_8_1_1"
],
"InParanoid": [
"P35346"
],
"OMA": [
"QEDFQTC"
],
"OrthoDB": [
"5393360at2759"
],
"PhylomeDB": [
"P35346"
],
"TreeFam": [
"TF315737"
],
"PathwayCommons": [
"P35346"
],
"Reactome": [
"R-HSA-375276",
"R-HSA-418594"
],
"SignaLink": [
"P35346"
],
"SIGNOR": [
"P35346"
],
"BioGRID-ORCS": [
"6755"
],
"ChiTaRS": [
"SSTR5"
],
"GeneWiki": [
"Somatostatin_receptor_5"
],
"GenomeRNAi": [
"6755"
],
"Pharos": [
"P35346"
],
"PRO": [
"PR:P35346"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"P35346"
],
"Bgee": [
"ENSG00000162009"
],
"GO": [
"GO:0043005",
"GO:0005886",
"GO:0042923",
"GO:0004994",
"GO:0071385",
"GO:0007186",
"GO:0007187",
"GO:0008285",
"GO:0007218",
"GO:0032467",
"GO:0050796"
],
"CDD": [
"cd15974"
],
"Gene3D": [
"1.20.1070.10"
],
"InterPro": [
"IPR000276",
"IPR017452",
"IPR000586",
"IPR001184"
],
"PANTHER": [
"PTHR24229",
"PTHR24229:SF20"
],
"Pfam": [
"PF00001"
],
"PRINTS": [
"PR00237",
"PR00246",
"PR00591"
],
"SMART": [
"SM01381"
],
"SUPFAM": [
"SSF81321"
],
"PROSITE": [
"PS00237",
"PS50262"
]
},
"citations": [
{
"title": "Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28.",
"pubmedID": "7908405"
},
{
"title": "Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype.",
"pubmedID": "8373420",
"doi": "10.1006\/bbrc.1993.2122"
},
{
"title": "Characterization of cloned human somatostatin receptor SSTR5.",
"pubmedID": "8078491"
},
{
"title": "Identification of an upstream pituitary-active promoter of human somatostatin receptor subtype 5.",
"pubmedID": "12072395",
"doi": "10.1210\/endo.143.7.8883"
},
{
"title": "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.",
"pubmedID": "11157797",
"doi": "10.1093\/hmg\/10.4.339"
},
{
"title": "The sequence and analysis of duplication-rich human chromosome 16.",
"pubmedID": "15616553",
"doi": "10.1038\/nature03187"
},
{
"title": "Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization.",
"pubmedID": "18653781",
"doi": "10.1210\/me.2007-0334"
},
{
"title": "Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase.",
"pubmedID": "21820437",
"doi": "10.1016\/j.febslet.2011.07.028"
}
],
"sequence": {
"length": 364,
"mass": 39202,
"checksum": "905744715F31121C",
"modified": {
"$date": {
"$numberLong": "975628800000"
}
},
"version": 3,
"sequence": "MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL"
},
"existence": 0,
"relevance": 1,
"proteinID": 1760088671
}
],
"singleCellExpressions": {
"cellSignificanceIndex": []
}
}