Details for: TMEM184B AS1

Gene ID: 128385376

Symbol: TMEM184B AS1

Ensembl ID: ENSG00000235246

Description: TMEM184B antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.1454
    Cell Significance Index: 27.7500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.1989
    Cell Significance Index: 3.4000
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.1661
    Cell Significance Index: 2.6900
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.1287
    Cell Significance Index: 1.7700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.1261
    Cell Significance Index: 3.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0616
    Cell Significance Index: 3.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0408
    Cell Significance Index: 1.8500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0403
    Cell Significance Index: 0.6400
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.0323
    Cell Significance Index: 0.3900
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.0214
    Cell Significance Index: 0.1700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0173
    Cell Significance Index: 1.9800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.0169
    Cell Significance Index: 0.2400
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.0115
    Cell Significance Index: 0.1200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0063
    Cell Significance Index: 1.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0057
    Cell Significance Index: 1.1400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0051
    Cell Significance Index: 0.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0045
    Cell Significance Index: 0.9000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0042
    Cell Significance Index: 1.2000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0028
    Cell Significance Index: 1.0000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0024
    Cell Significance Index: 0.3500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0016
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0013
    Cell Significance Index: 2.4200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0013
    Cell Significance Index: 1.8400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0009
    Cell Significance Index: 1.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0009
    Cell Significance Index: 1.3200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0004
    Cell Significance Index: 0.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0007
    Cell Significance Index: -0.4400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0015
    Cell Significance Index: -0.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0017
    Cell Significance Index: -0.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0020
    Cell Significance Index: -1.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0022
    Cell Significance Index: -0.9800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0022
    Cell Significance Index: -0.1100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0024
    Cell Significance Index: -0.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0026
    Cell Significance Index: -0.0900
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0036
    Cell Significance Index: -0.0500
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.0042
    Cell Significance Index: -0.0400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0043
    Cell Significance Index: -0.1400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0052
    Cell Significance Index: -0.1700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0053
    Cell Significance Index: -1.1100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0054
    Cell Significance Index: -0.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0064
    Cell Significance Index: -1.1000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0070
    Cell Significance Index: -0.5400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0079
    Cell Significance Index: -1.0200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0081
    Cell Significance Index: -0.1400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0085
    Cell Significance Index: -0.8900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0088
    Cell Significance Index: -0.9000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0094
    Cell Significance Index: -0.2700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0101
    Cell Significance Index: -0.2100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0106
    Cell Significance Index: -0.2700
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0120
    Cell Significance Index: -0.1600
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: -0.0120
    Cell Significance Index: -0.1300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0125
    Cell Significance Index: -0.2700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0127
    Cell Significance Index: -0.9500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0130
    Cell Significance Index: -0.2800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0130
    Cell Significance Index: -0.3300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0132
    Cell Significance Index: -0.7400
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.0132
    Cell Significance Index: -0.1800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0148
    Cell Significance Index: -0.5200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0152
    Cell Significance Index: -0.4800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0154
    Cell Significance Index: -0.4100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0155
    Cell Significance Index: -0.4200
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0155
    Cell Significance Index: -0.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0167
    Cell Significance Index: -0.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0174
    Cell Significance Index: -0.8200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0182
    Cell Significance Index: -0.3800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0196
    Cell Significance Index: -0.4900
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.0201
    Cell Significance Index: -0.2600
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0203
    Cell Significance Index: -0.3500
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0211
    Cell Significance Index: -0.3200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0228
    Cell Significance Index: -0.4500
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0241
    Cell Significance Index: -0.4800
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0244
    Cell Significance Index: -0.2200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0250
    Cell Significance Index: -0.6800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0255
    Cell Significance Index: -1.1300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0258
    Cell Significance Index: -0.7400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0261
    Cell Significance Index: -0.5100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0265
    Cell Significance Index: -0.5800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0267
    Cell Significance Index: -1.1600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0280
    Cell Significance Index: -0.4500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0283
    Cell Significance Index: -0.3700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0293
    Cell Significance Index: -0.4200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0298
    Cell Significance Index: -1.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0325
    Cell Significance Index: -0.6800
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0331
    Cell Significance Index: -0.3200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0343
    Cell Significance Index: -1.2600
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0343
    Cell Significance Index: -0.3300
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: -0.0350
    Cell Significance Index: -0.3700
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0363
    Cell Significance Index: -0.4600
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0377
    Cell Significance Index: -0.3900
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0381
    Cell Significance Index: -0.7600
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.0387
    Cell Significance Index: -0.4200
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.0398
    Cell Significance Index: -0.4900
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0398
    Cell Significance Index: -0.5100
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.0414
    Cell Significance Index: -0.4500
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.0424
    Cell Significance Index: -0.4500
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0425
    Cell Significance Index: -0.5900
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0434
    Cell Significance Index: -0.4500
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: -0.0438
    Cell Significance Index: -0.4900
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0442
    Cell Significance Index: -0.4700
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0445
    Cell Significance Index: -0.2900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TMEM184B AS1 is a non-coding RNA gene, meaning that it does not encode a protein. Despite its non-coding nature, TMEM184B AS1 has been found to regulate gene expression through various mechanisms, including antisense RNA-mediated interference (RNAi) and chromatin remodeling. The gene is also characterized by its high expression levels in certain cell types, such as glial cells and intestinal epithelial cells, where it is thought to play a role in maintaining tissue homeostasis. One of the most striking features of TMEM184B AS1 is its ability to regulate the expression of other genes. Studies have shown that TMEM184B AS1 can bind to and regulate the expression of genes involved in various cellular processes, including cell proliferation, differentiation, and survival. This regulatory function is thought to be mediated by the antisense RNAi mechanism, where TMEM184B AS1 competes with sense RNA molecules for binding to specific microRNA binding sites, thereby regulating the expression of target genes. **Pathways and Functions** TMEM184B AS1 has been implicated in various cellular pathways, including the regulation of cell proliferation, differentiation, and survival. In the context of glial cells, TMEM184B AS1 has been shown to regulate the expression of genes involved in the maintenance of glial cell identity and function. In intestinal epithelial cells, TMEM184B AS1 is thought to play a role in regulating the expression of genes involved in the maintenance of intestinal homeostasis and the prevention of disease. One of the most significant pathways associated with TMEM184B AS1 is the regulation of the Wnt/β-catenin signaling pathway. Studies have shown that TMEM184B AS1 can bind to and regulate the expression of Wnt/β-catenin target genes, thereby modulating the activity of this critical signaling pathway. The Wnt/β-catenin pathway is involved in a wide range of cellular processes, including cell proliferation, differentiation, and survival, and dysregulation of this pathway has been implicated in various diseases, including cancer and neurodegenerative disorders. **Clinical Significance** TMEM184B AS1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and gastrointestinal diseases. In the context of cancer, TMEM184B AS1 has been shown to regulate the expression of genes involved in cell proliferation, differentiation, and survival, thereby modulating the activity of the Wnt/β-catenin signaling pathway. Aberrant expression of TMEM184B AS1 has been observed in various types of cancer, including colorectal cancer, breast cancer, and lung cancer. In the context of neurodegenerative disorders, TMEM184B AS1 has been implicated in the regulation of gene expression in the brain. Studies have shown that TMEM184B AS1 is expressed in the cerebral cortex and hippocampus, where it regulates the expression of genes involved in neuronal function and survival. Aberrant expression of TMEM184B AS1 has been observed in various neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. In the context of gastrointestinal diseases, TMEM184B AS1 has been implicated in the regulation of gene expression in the intestinal epithelium. Studies have shown that TMEM184B AS1 regulates the expression of genes involved in the maintenance of intestinal homeostasis and the prevention of disease. Aberrant expression of TMEM184B AS1 has been observed in various gastrointestinal diseases, including inflammatory bowel disease and irritable bowel syndrome. In summary, TMEM184B AS1 is a non-coding RNA gene that plays a critical role in regulating gene expression in various tissues and cell types. Its ability to regulate the expression of genes involved in cellular processes such as cell proliferation, differentiation, and survival makes it a potential therapeutic target for various diseases, including cancer, neurodegenerative disorders, and gastrointestinal diseases. Further research is needed to fully understand the mechanisms by which TMEM184B AS1 regulates gene expression and to explore its potential as a therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.