Details for: NOL4L
Gene ID: 140688
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: NOL4L
Ensembl ID: ENSG00000197183
Description: nucleolar protein 4 like
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 14.87rCSI 20.31%PRS 83.17
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CSI 6.78rCSI 6.53%PRS 83.24
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CSI 6.37rCSI 9.73%PRS 87.11
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CSI 5.55rCSI 8.86%PRS 87.08
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CSI 4.73rCSI 10.61%PRS 68.07
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CSI 4.44rCSI 10.79%PRS 65.01
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CSI 4.24rCSI 5.45%PRS 80.18
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CSI 4.02rCSI 10.47%PRS 84.9
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CSI 3.92rCSI 14.82%PRS 67.61
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CSI 3.83rCSI 2.69%PRS 94.03
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CSI 3.54rCSI 7.35%PRS 80.92
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CSI 3.47rCSI 2.75%PRS 74.07
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CSI 3.45rCSI 5.97%PRS 76.15
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CSI 3.41rCSI 3.56%PRS 81.44
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CSI 3.34rCSI 3.15%PRS 82.13
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CSI 3.3rCSI 2.9%PRS 73.77
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CSI 3.2rCSI 5.76%PRS 77.69
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CSI 3.2rCSI 2.4%PRS 89.05
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CSI 3.07rCSI 3.71%PRS 90.52
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CSI 3.06rCSI 5.01%PRS 74.27
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CSI 3.06rCSI 15.06%PRS 90
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CSI 2.99rCSI 4.81%PRS 82.25
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CSI 2.91rCSI 4.27%PRS 77.29
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CSI 2.88rCSI 2.53%PRS 88.33
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CSI 2.88rCSI 2.62%PRS 93.53
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CSI 2.84rCSI 5.7%PRS 75.24
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CSI 2.78rCSI 2.68%PRS 78.24
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CSI 2.75rCSI 2.22%PRS 91.04
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CSI 2.73rCSI 5.41%PRS 79.74
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CSI 2.63rCSI 5.01%PRS 91.75
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CSI 2.58rCSI 3.21%PRS 65.06
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CSI 2.54rCSI 2.93%PRS 76.31
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CSI 2.53rCSI 14.91%PRS 67.62
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CSI 2.52rCSI 4.42%PRS 78.37
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CSI 2.49rCSI 10.03%PRS 83.99
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CSI 2.45rCSI 3.16%PRS 68.33
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CSI 2.43rCSI 2.16%PRS 81.61
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CSI 2.43rCSI 7.6%PRS 68.68
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CSI 2.31rCSI 1.78%PRS 87.11
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CSI 2.28rCSI 5.26%PRS 72.44
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CSI 2.21rCSI 2.26%PRS 91.84
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CSI 2.2rCSI 3.22%PRS 78.78
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CSI 2.18rCSI 2.29%PRS 81.34
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CSI 2.17rCSI 3.58%PRS 87.28
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CSI 2.09rCSI 4.63%PRS 83.5
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CSI 2.02rCSI 7.28%PRS 65.04
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CSI 2rCSI 2.35%PRS 85.3
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CSI 1.97rCSI 1.82%PRS 85.25
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CSI 1.97rCSI 3.47%PRS 79.24
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CSI 1.96rCSI 2.34%PRS 67.21
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CSI 1.72rCSI 1.99%PRS 76.9
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CSI 1.63rCSI 38.96%PRS 65.06
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CSI 1.63rCSI 2.22%PRS 76
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CSI 1.57rCSI 2.26%PRS 83.66
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CSI 1.5rCSI 2.22%PRS 92.05
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CSI 1.48rCSI 2.38%PRS 68.57
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CSI 1.47rCSI 3.41%PRS 88.16
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CSI 1.46rCSI 2.76%PRS 90.6
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CSI 1.42rCSI 3.98%PRS 89.22
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CSI 1.41rCSI 4.01%PRS 79.62
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CSI 1.39rCSI 1.25%PRS 82.46
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CSI 1.38rCSI 2.23%PRS 74.59
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CSI 1.38rCSI 2.58%PRS 73.09
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CSI 1.37rCSI 33.09%PRS 65.55
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CSI 1.36rCSI 2.29%PRS 67.1
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CSI 1.35rCSI 3.2%PRS 87.78
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CSI 1.32rCSI 3.56%PRS 87.51
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CSI 1.31rCSI 2.86%PRS 88.14
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CSI 1.29rCSI 5.68%PRS 72.45
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CSI 1.28rCSI 3.07%PRS 71.14
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CSI 1.24rCSI 3.15%PRS 75.15
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CSI 1.24rCSI 2.19%PRS 66.69
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CSI 1.22rCSI 3.53%PRS 73.84
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CSI 1.18rCSI 3.87%PRS 70.19
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CSI 1.13rCSI 5.15%PRS 95.56
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CSI 0.88rCSI 1.94%PRS 70.54
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CSI 0.85rCSI 6.27%PRS 72.25
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CSI 0.75rCSI 4.26%PRS 70.54
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CSI 0.71rCSI 2.22%PRS 70.97
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CSI 0.71rCSI 3.14%PRS 84.57
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CSI 0.7rCSI 3.04%PRS 87.79
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CSI 0.33rCSI 5.22%PRS 85.05
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CSI 0.26rCSI 2.27%PRS 72.77
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
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Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1116020775
Symbol: NOL4L_HUMAN
Name: Nucleolar protein 4-like
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 436
- Mass: 47215
- Checksum: 139A07537D875DF8
- Sequence:
MSDSTWMSAD PHLASSLSPS QDERMRSPQN LHSQEDDDSS SESGSGNGSS TLNPSTSSST QGDPAFPEMN GNGAVAPMDF TTAAEDQPIN LCDKLPPATA LGTASYPSDG CGADGLRSRV KYGVKTTPES PPYSSGSYDS IKTEVSGCPE DLTVGRAPTA DDDDDDHDDH EDNDKMNDSE GMDPERLKAF NMFVRLFVDE NLDRMVPISK QPKEKIQAII ESCSRQFPEF QERARKRIRT YLKSCRRMKK NGMEMTRPTP PHLTSAMAEN ILAAACESET RKAAKRMRLE IYQSSQDEPI ALDKQHSRDS AAITHSTYSL PASSYSQDPV YANGGLNYSY RGYGALSSNL QPPASLQTGN HSNGPTDLSM KGGASTTSTT PTPTPSSTST SRPVPTAQLS PTEISAVRQL IAGYRESAAF LLRSADELEN LILQQN
Genular Protein ID: 93901777
Symbol: A0A087X0N3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 680
- Mass: 74224
- Checksum: EE242B95A12C5497
- Sequence:
MPKPTLLLRG GWERERSPGD SELGRQFRDW CLRTYGDSAK TKTVTRSKYQ RIAEVLQGGG GTGAGSGPAA GEKGKFQFWV RSKGFRLGSG REPKMGQVVY VPVKTGSGAD GLSEPEGISL KRVAVVEDFF DIIYSMHVES SAEPGKAPKH AGQKKTYRAI AETYAFLPRE AVTRFLMSCT ECQKRMHFNS NGLEPKENEP PSPLVSGIID YNMPLTSTYL KQMKLRVMNS QEQDETSVSS EDFDMSDSTW MSADPHLASS LSPSQDERMR SPQNLHSQED DDSSSESGSG NGSSTLNPST SSSTQGDPAF PEMNGNGAVA PMDFTTAAED QPINLCDKLP PATALGTASY PSDGCGADGL RSRVKYGVKT TPESPPYSSG SYDSIKTEVS GCPEDLTVGR APTADDDDDD HDDHEDNDKM NDSEGMDPER LKAFNMFVRL FVDENLDRMV PISKQPKEKI QAIIESCSRQ FPEFQERARK RIRTYLKSCR RMKKNGMEMT RPTPPHLTSA MAENILAAAC ESETRKAAKR MRLEIYQSSQ DEPIALDKQH SRDSAAITHS TYSLPASSYS QDPVYANGGL NYSYRGYGAL SSNLQPPASL QTGNHSNGPT DLSMKGGAST TSTTPTPTPS STSTSRPVPT AQLSPTEISA VRQLIAGYRE SAAFLLRSAD ELENLILQQN
Genular Protein ID: 4272981809
Symbol: Q6P0R2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 206
- Mass: 22384
- Checksum: 14F0685C3FC81353
- Sequence:
RAAAPRVRPP PAPIQQPRRS HTAGQTRPRR VPARSSPAQP SPGTGRPGGR PAPEGAGRGG RMPKPTLLLR GGWERERSPG DSELGRQFRD WCLRTYGDSA KTKTVTRSKY QRIAEVLQGG GGTGAGSGPA AGEKGKFQFW VRSKGFRLGS GREPKMGQVV YVPVKTGSLC SIQFYGCTII YLSSPLLMDI WIVYDILLSQ DFSEHP