Details for: ADGRE1

Gene ID: 2015

Symbol: ADGRE1

Ensembl ID: ENSG00000174837

Description: adhesion G protein-coupled receptor E1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 6.2584
    Cell Significance Index: -2.5400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 5.3073
    Cell Significance Index: -2.7300
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 1.7646
    Cell Significance Index: 4.6600
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.7044
    Cell Significance Index: 24.7500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.4920
    Cell Significance Index: 12.2700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3656
    Cell Significance Index: 8.0100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3322
    Cell Significance Index: 6.1400
  • Cell Name: epithelial cell of sweat gland (CL1000448)
    Fold Change: 0.3218
    Cell Significance Index: 0.2300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2568
    Cell Significance Index: 4.4000
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.2442
    Cell Significance Index: 3.5000
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.1903
    Cell Significance Index: 1.0000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.1283
    Cell Significance Index: 0.8700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0599
    Cell Significance Index: 1.7600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0496
    Cell Significance Index: 0.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0169
    Cell Significance Index: 3.3600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0168
    Cell Significance Index: 3.3800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0068
    Cell Significance Index: 0.1000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0046
    Cell Significance Index: 0.6700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0032
    Cell Significance Index: 6.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0021
    Cell Significance Index: 0.7600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0018
    Cell Significance Index: 2.7200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0015
    Cell Significance Index: 2.7500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0012
    Cell Significance Index: 1.6600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0015
    Cell Significance Index: -0.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0022
    Cell Significance Index: -1.3800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0029
    Cell Significance Index: -2.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0031
    Cell Significance Index: -1.4000
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.0034
    Cell Significance Index: -0.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0037
    Cell Significance Index: -1.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0045
    Cell Significance Index: -2.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0105
    Cell Significance Index: -1.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0106
    Cell Significance Index: -1.0800
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0122
    Cell Significance Index: -0.2100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0123
    Cell Significance Index: -0.6200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0153
    Cell Significance Index: -1.8800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0173
    Cell Significance Index: -2.3800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0180
    Cell Significance Index: -1.2100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0183
    Cell Significance Index: -0.9500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0189
    Cell Significance Index: -1.9700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0193
    Cell Significance Index: -0.7900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0204
    Cell Significance Index: -2.4000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0262
    Cell Significance Index: -1.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0266
    Cell Significance Index: -2.0400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0266
    Cell Significance Index: -1.6300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0283
    Cell Significance Index: -0.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0293
    Cell Significance Index: -1.1100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0342
    Cell Significance Index: -2.1000
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0356
    Cell Significance Index: -0.4400
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0358
    Cell Significance Index: -0.2900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0367
    Cell Significance Index: -1.7300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0370
    Cell Significance Index: -1.1700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0386
    Cell Significance Index: -1.2300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0404
    Cell Significance Index: -1.0100
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0405
    Cell Significance Index: -0.9800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0406
    Cell Significance Index: -2.6200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0434
    Cell Significance Index: -1.4200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0438
    Cell Significance Index: -2.4600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0450
    Cell Significance Index: -1.5800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0466
    Cell Significance Index: -2.4200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0485
    Cell Significance Index: -1.0300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0501
    Cell Significance Index: -0.9800
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0522
    Cell Significance Index: -0.4600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0581
    Cell Significance Index: -2.7100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0617
    Cell Significance Index: -1.5400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0618
    Cell Significance Index: -1.5800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0630
    Cell Significance Index: -1.2300
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0643
    Cell Significance Index: -0.6500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0659
    Cell Significance Index: -1.3400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0669
    Cell Significance Index: -1.9100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0674
    Cell Significance Index: -0.9200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0683
    Cell Significance Index: -1.4800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0689
    Cell Significance Index: -1.8400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0698
    Cell Significance Index: -1.3800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0699
    Cell Significance Index: -0.5700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0702
    Cell Significance Index: -1.4100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0726
    Cell Significance Index: -2.5500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0768
    Cell Significance Index: -2.0900
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0779
    Cell Significance Index: -1.1400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0801
    Cell Significance Index: -1.2400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0804
    Cell Significance Index: -2.9500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0808
    Cell Significance Index: -1.1500
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: -0.0820
    Cell Significance Index: -0.7500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0826
    Cell Significance Index: -1.0800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0848
    Cell Significance Index: -1.7700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0855
    Cell Significance Index: -2.4500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0871
    Cell Significance Index: -1.4800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0894
    Cell Significance Index: -2.3500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0895
    Cell Significance Index: -2.5800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0899
    Cell Significance Index: -2.3100
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0903
    Cell Significance Index: -1.2000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0918
    Cell Significance Index: -2.2400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0919
    Cell Significance Index: -2.2100
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0925
    Cell Significance Index: -1.8200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0928
    Cell Significance Index: -1.3700
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0966
    Cell Significance Index: -2.4600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0966
    Cell Significance Index: -1.0000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0981
    Cell Significance Index: -0.9300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1003
    Cell Significance Index: -2.0000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1018
    Cell Significance Index: -1.7600
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.1063
    Cell Significance Index: -1.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ADGRE1 is a transmembrane receptor, comprising an extracellular domain with an EGF-like module and a cytoplasmic tail. Its expression is predominantly found in epithelial cells, immune cells, and stem cells, indicating its involvement in cell-cell interactions and immune regulation. ADGRE1 is also known as EGF-like module receptor 1 (EGFR1) and is encoded by the ADGRE1 gene. **Pathways and Functions:** ADGRE1 is activated by various ligands, including prostaglandin E2 (PGE2), leukotriene D4 (LTD4), and other inflammatory mediators. Upon activation, ADGRE1 triggers a signaling cascade that involves the activation of G proteins, leading to the production of cAMP and subsequent cellular responses. The main signaling pathways associated with ADGRE1 include: 1. **Adenylate cyclase-activating G protein-coupled receptor signaling pathway**: ADGRE1 stimulates the activation of adenylate cyclase, resulting in increased cAMP production and modulation of downstream signaling pathways. 2. **Cell adhesion**: ADGRE1 interacts with other cell surface receptors, facilitating cell-cell interactions and adhesion, particularly in the context of immune responses and inflammation. 3. **Calcium ion binding**: ADGRE1 can bind to calcium ions, influencing calcium-dependent signaling pathways and cellular responses. **Clinical Significance:** ADGRE1's involvement in immune response and inflammation makes it a potential target for therapeutic interventions in various diseases, including: 1. **Asthma**: ADGRE1's role in airway inflammation and smooth muscle contraction makes it a potential target for asthma treatment. 2. **Inflammatory bowel disease**: ADGRE1's involvement in intestinal inflammation and immune regulation suggests its potential as a therapeutic target in IBD. 3. **Autoimmune diseases**: ADGRE1's expression in immune cells and its role in immune regulation imply its potential involvement in autoimmune diseases, such as rheumatoid arthritis and lupus. 4. **Cancer**: ADGRE1's expression in cancer cells and its potential role in tumor progression and metastasis make it a promising target for cancer therapy. In conclusion, ADGRE1 is a multifunctional receptor that plays a crucial role in immune response, inflammation, and cellular adhesion. Its involvement in various diseases highlights the potential for therapeutic interventions targeting this receptor. Further research is needed to fully elucidate the functions of ADGRE1 and its implications in human disease.

Genular Protein ID: 3573759261

Symbol: AGRE1_HUMAN

Name: EGF-like module receptor 1

UniProtKB Accession Codes:

Q14246 A6NHV2 B7Z486 B7Z489 E7EPX9 E9PD45 H9KV79 Q2I7G5 Q6ZMN0 Q8NGA7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 5 ExpressionAtlas 1 GO 9 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 7 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 Reactome 1 RefSeq 5 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7601460

Title: EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments.

PubMed ID: 7601460

DOI: 10.1016/0888-7543(95)80218-b

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17823986

Title: EMR1, the human homolog of F4/80, is an eosinophil-specific receptor.

PubMed ID: 17823986

DOI: 10.1002/eji.200737553

PubMed ID: 24530099

Title: The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): a novel therapeutic target for eosinophilic disorders.

PubMed ID: 24530099

DOI: 10.1016/j.jaci.2013.11.041

PubMed ID: 25713288

Title: International union of basic and clinical pharmacology. XCIV. Adhesion G protein-coupled receptors.

PubMed ID: 25713288

DOI: 10.1124/pr.114.009647

Sequence Information:

  • Length: 886
  • Mass: 97683
  • Checksum: 07322996EEF5A6F1
  • Sequence:
    • MRGFNLLLFW GCCVMHSWEG HIRPTRKPNT KGNNCRDSTL CPAYATCTNT VDSYYCACKQ 
GFLSSNGQNH FKDPGVRCKD IDECSQSPQP CGPNSSCKNL SGRYKCSCLD GFSSPTGNDW 
VPGKPGNFSC TDINECLTSS VCPEHSDCVN SMGSYSCSCQ VGFISRNSTC EDVDECADPR 
ACPEHATCNN TVGNYSCFCN PGFESSSGHL SFQGLKASCE DIDECTEMCP INSTCTNTPG 
SYFCTCHPGF APSNGQLNFT DQGVECRDID ECRQDPSTCG PNSICTNALG SYSCGCIAGF 
HPNPEGSQKD GNFSCQRVLF KCKEDVIPDN KQIQQCQEGT AVKPAYVSFC AQINNIFSVL 
DKVCENKTTV VSLKNTTESF VPVLKQISTW TKFTKEETSS LATVFLESVE SMTLASFWKP 
SANITPAVRT EYLDIESKVI NKECSEENVT LDLVAKGDKM KIGCSTIEES ESTETTGVAF 
VSFVGMESVL NERFFKDHQA PLTTSEIKLK MNSRVVGGIM TGEKKDGFSD PIIYTLENIQ 
PKQKFERPIC VSWSTDVKGG RWTSFGCVIL EASETYTICS CNQMANLAVI MASGELTMDF 
SLYIISHVGI IISLVCLVLA IATFLLCRSI RNHNTYLHLH LCVCLLLAKT LFLAGIHKTD 
NKMGCAIIAG FLHYLFLACF FWMLVEAVIL FLMVRNLKVV NYFSSRNIKM LHICAFGYGL 
PMLVVVISAS VQPQGYGMHN RCWLNTETGF IWSFLGPVCT VIVINSLLLT WTLWILRQRL 
SSVNAEVSTL KDTRLLTFKA FAQLFILGCS WVLGIFQIGP VAGVMAYLFT IINSLQGAFI 
FLIHCLLNGQ VREEYKRWIT GKTKPSSQSQ TSRILLSSMP SASKTG

Genular Protein ID: 2702111616

Symbol: A8K653_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K653

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 3 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 3 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 821
  • Mass: 90334
  • Checksum: 0DD2C0AF81639AFA
  • Sequence:
    • MRGFNLLLFW GCCVMHSWEG HIRPTRKPNT KGNNCRDSTL CPAYATCTNT VDSYYCACKQ 
GFLSSNGQNH FKDPGVRCKD IDECSQSPQP CGPNSSCKNL SGRYKCSCLD GFSSPTGNDW 
VPGKPGNFSC TDINECLTSS VCPEHSDCVN SMGSYSCICQ VGFISRNSTC EDVDECADPR 
ACPEHATCNS TVGNFSCFCN PGFESSSGHL SFQGLKASCE DIDECTEMCP INSTCTNTPG 
SYFCTCHPGF APSNGQLNFT DQGVECRDID ECRQDPSTCG PNSICTNALG SYSCGCIAGF 
HPNPEGSQKD GNFSCQRVLF KCKEDVIPDN KQIQQCQEGT AVKPAYVSFC AQINNIFSVL 
DKVCENKTTV VSLKNTTESF VPVLKQISMW TKFTKEETSS LATVFLESVE SMTLASFWKP 
SANVTPAVRT EYLDIESKVI NKECSEENVT LDLVAKGDKM KIGCSTIEES ESTETTGVAF 
VSFVGMESVL NERFFQDHQA PLTTSEIKLK MNSRVVGGIM TGEKKDGFSD PIIYTLENVQ 
PKQKFERPIC VSWSTDVKGG RWTSFGCVIL EASETYTICS CNQMANLAVI MASGELTTGC 
AIIAGFLHYL FLACFFWMLV EAVILFLMVR NLKVVNYFSS RNIKMLHICA FGYGLPMLVV 
VISASVQPQG YGMHNRCWLN TETGFIWSFL GPVCTVIVIN SLLLTWTLWI LRQRLSSVNA 
EVSTLKDTRL LTFKAFAQLF ILGCSWVLGI FQIGPVAGVM AYLFTIINSL QGAFIFLIHC 
LLNGQVREEY KRWITGKTKP SSQSQTSRIL LSSMPSASKT G

Genular Protein ID: 1205474800

Symbol: A8K2Y6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K2Y6

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 3 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 3 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 889
  • Mass: 97998
  • Checksum: E61DE6022E5A961E
  • Sequence:
    • MRGFNLLLFW GCCVMHSWEG HIRPTRKPNT KGNNCRDSTL CPAYATCTNT VDSYYCACKQ 
GFLSSNGQNH FKDPGVRCKD IDECSQSPQP CGPNSSCKNL SGRYKCSCLD GFSSPTGNDW 
VPGKPGNFSC TDINECLTSS VCPEHSDCVN SMGSYSCSCQ VGFISRNSTC EDVDECADPR 
ACPEHATCNN TVGNYSCFCN PGFESSSGHL SFQGLKASCE DIDECTEMCP INSTCTNTPG 
SYFCTCHPGF APSNGQLNFT DQGVECRDID ECRQDPSTCG PNSICTNALG SYSCGCIAGF 
HPNPEGSQKD GNFSCQRVLF KCKEDVIPDN KQIQQCQEGT AVKPAYVSFC AQINNIFSVL 
DKVCENKTTV VSLKNTTESF VPVLKQISTW TKFTKEETSS LATVFLESVE SMTLASFWKP 
SANVTPAVRT EYLDIESKVI NKECSEENVT LDLVAKGDKM KIGCSTIEES ESTETTGVAF 
VSFVGMESVL NERFFQDHQA PLTTSEIKLK MNSRVVGGIM TGEKKDGFSD PIIYTLENVQ 
PKQKFERPIC VSWSTDVKGG RWTSFGCVIL EASETYTICS CNQMANLAVI MASGELTMDF 
SLYIISHVGI IISLVCLVLA IATFLLCRSI RNHNTYLHLH LCVCLLLAKT LFLAGIHKTD 
NKMGCAIIAG FLHYLFLACF FWMLVEAVIL FLMVRNLKVV NYFSSRNIKM LHICAFGYGL 
PMLVVVISAS VQPQGYGMHN RCWLNTETGF IWSFLGPVCT VIVTLQINSL LLTWTLWILR 
QRLSSVNAEV STLKDTRLLT FKAFAQLFIL GCSWVLGIFQ IGPVAGVMAY LFTIINSLQG 
AFIFLIHCLL NGQVREEYKR WITGKTKPSS QSQTSRILLS SMPSASKTG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.