FGF10 | ENSG00000070193 | NCBI 2255

Details for: FGF10

Gene ID: 2255

Symbol: FGF10

Ensembl ID: ENSG00000070193

Description: fibroblast growth factor 10

Associated with

Activated point mutants of fgfr2
(R-HSA-2033519)
Constitutive signaling by aberrant pi3k in cancer
(R-HSA-2219530)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Downstream signaling of activated fgfr1
(R-HSA-5654687)
Downstream signaling of activated fgfr2
(R-HSA-5654696)
Fgfr1 ligand binding and activation
(R-HSA-190242)
Fgfr1b ligand binding and activation
(R-HSA-190370)
Fgfr2 ligand binding and activation
(R-HSA-190241)
Fgfr2 mutant receptor activation
(R-HSA-1839126)
Fgfr2b ligand binding and activation
(R-HSA-190377)
Fgfrl1 modulation of fgfr1 signaling
(R-HSA-5658623)
Frs-mediated fgfr1 signaling
(R-HSA-5654693)
Frs-mediated fgfr2 signaling
(R-HSA-5654700)
Igf1r signaling cascade
(R-HSA-2428924)
Insulin receptor signalling cascade
(R-HSA-74751)
Intracellular signaling by second messengers
(R-HSA-9006925)
Irs-mediated signalling
(R-HSA-112399)
Irs-related events triggered by igf1r
(R-HSA-2428928)
Mapk1/mapk3 signaling
(R-HSA-5684996)
Mapk family signaling cascades
(R-HSA-5683057)
Negative regulation of fgfr1 signaling
(R-HSA-5654726)
Negative regulation of fgfr2 signaling
(R-HSA-5654727)
Negative regulation of the pi3k/akt network
(R-HSA-199418)
Phospholipase c-mediated cascade: fgfr1
(R-HSA-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-HSA-5654221)
Pi-3k cascade:fgfr1
(R-HSA-5654689)
Pi-3k cascade:fgfr2
(R-HSA-5654695)
Pi3k/akt signaling in cancer
(R-HSA-2219528)
Pi3k cascade
(R-HSA-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-HSA-6811558)
Pip3 activates akt signaling
(R-HSA-1257604)
Raf/map kinase cascade
(R-HSA-5673001)
Regulation of beta-cell development
(R-HSA-186712)
Regulation of gene expression in early pancreatic precursor cells
(R-HSA-210747)
Shc-mediated cascade:fgfr1
(R-HSA-5654688)
Shc-mediated cascade:fgfr2
(R-HSA-5654699)
Signaling by fgfr
(R-HSA-190236)
Signaling by fgfr1
(R-HSA-5654736)
Signaling by fgfr2
(R-HSA-5654738)
Signaling by fgfr2 in disease
(R-HSA-5655253)
Signaling by fgfr in disease
(R-HSA-1226099)
Signaling by insulin receptor
(R-HSA-74752)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-HSA-2404192)
Signal transduction
(R-HSA-162582)
Actin cytoskeleton organization
(GO:0030036)
Angiogenesis
(GO:0001525)
Blood vessel remodeling
(GO:0001974)
Chemoattractant activity
(GO:0042056)
Determination of left/right symmetry
(GO:0007368)
Embryonic camera-type eye development
(GO:0031076)
Embryonic genitalia morphogenesis
(GO:0030538)
Embryonic pattern specification
(GO:0009880)
Endothelial cell proliferation
(GO:0001935)
Establishment of mitotic spindle orientation
(GO:0000132)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Growth factor activity
(GO:0008083)
Hair follicle morphogenesis
(GO:0031069)
Heparin binding
(GO:0008201)
Lacrimal gland development
(GO:0032808)
Mesonephros development
(GO:0001823)
Metanephros development
(GO:0001656)
Metanephros morphogenesis
(GO:0003338)
Muscle cell fate commitment
(GO:0042693)
Negative regulation of epithelial cell differentiation
(GO:0030857)
Neurogenesis
(GO:0022008)
Odontogenesis of dentin-containing tooth
(GO:0042475)
Organ induction
(GO:0001759)
Otic vesicle formation
(GO:0030916)
Pancreas development
(GO:0031016)
Pituitary gland development
(GO:0021983)
Positive regulation of atp-dependent activity
(GO:0032781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of keratinocyte proliferation
(GO:0010838)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of vascular endothelial growth factor receptor signaling pathway
(GO:0030949)
Protein binding
(GO:0005515)
Protein localization to cell surface
(GO:0034394)
Regulation of activin receptor signaling pathway
(GO:0032925)
Regulation of cell migration
(GO:0030334)
Regulation of smoothened signaling pathway
(GO:0008589)
Response to estradiol
(GO:0032355)
Response to lipopolysaccharide
(GO:0032496)
Salivary gland development
(GO:0007431)
Somatic stem cell population maintenance
(GO:0035019)
Thyroid gland development
(GO:0030878)
Tissue regeneration
(GO:0042246)
Type 2 fibroblast growth factor receptor binding
(GO:0005111)
Wnt signaling pathway
(GO:0016055)
Wound healing
(GO:0042060)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 7.7769
Cell Significance Index: 120.3200
Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 6.1535
Cell Significance Index: -5.8800
Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 5.9563
Cell Significance Index: 36.8500
Cell Name: preadipocyte (CL0002334)
Fold Change: 2.7955
Cell Significance Index: 54.5600
Cell Name: decidual cell (CL2000002)
Fold Change: 2.7095
Cell Significance Index: 43.4700
Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.8048
Cell Significance Index: 15.3400
Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.6623
Cell Significance Index: 25.2900
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.7887
Cell Significance Index: 39.8600
Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.6170
Cell Significance Index: 7.7700
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5338
Cell Significance Index: 191.4600
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.2564
Cell Significance Index: 7.3500
Cell Name: keratocyte (CL0002363)
Fold Change: 0.1494
Cell Significance Index: 2.3700
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.0981
Cell Significance Index: 3.4100
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0958
Cell Significance Index: 19.2200
Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0483
Cell Significance Index: 33.3900
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0374
Cell Significance Index: 5.1400
Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.0369
Cell Significance Index: 0.3100
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0308
Cell Significance Index: 1.7300
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0266
Cell Significance Index: 12.0900
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0169
Cell Significance Index: 2.8800
Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0167
Cell Significance Index: 22.6500
Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0156
Cell Significance Index: 24.0600
Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0043
Cell Significance Index: 7.9200
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0004
Cell Significance Index: 0.7300
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0078
Cell Significance Index: -5.9300
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0083
Cell Significance Index: -5.3000
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0091
Cell Significance Index: -6.7800
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0102
Cell Significance Index: -6.4000
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0113
Cell Significance Index: -6.4000
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0161
Cell Significance Index: -2.9100
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0165
Cell Significance Index: -4.7500
Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0203
Cell Significance Index: -0.3400
Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0227
Cell Significance Index: -4.5100
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0325
Cell Significance Index: -6.8400
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0338
Cell Significance Index: -4.9100
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0441
Cell Significance Index: -5.4200
Cell Name: lactocyte (CL0002325)
Fold Change: -0.0444
Cell Significance Index: -5.7400
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0448
Cell Significance Index: -5.1300
Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0457
Cell Significance Index: -0.6100
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0459
Cell Significance Index: -4.7800
Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0554
Cell Significance Index: -2.4100
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0558
Cell Significance Index: -3.5200
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0579
Cell Significance Index: -2.7200
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0602
Cell Significance Index: -1.2600
Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0620
Cell Significance Index: -0.6800
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0657
Cell Significance Index: -5.0400
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0737
Cell Significance Index: -5.4900
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0787
Cell Significance Index: -1.1200
Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0880
Cell Significance Index: -1.2600
Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0939
Cell Significance Index: -4.8900
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0956
Cell Significance Index: -3.1300
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0981
Cell Significance Index: -6.0300
Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.1037
Cell Significance Index: -1.0000
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.1049
Cell Significance Index: -1.1400
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1103
Cell Significance Index: -3.2500
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1103
Cell Significance Index: -4.8800
Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1230
Cell Significance Index: -6.4600
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1233
Cell Significance Index: -4.3200
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1233
Cell Significance Index: -5.7500
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1254
Cell Significance Index: -4.7500
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1280
Cell Significance Index: -5.8000
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1560
Cell Significance Index: -4.0100
Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1586
Cell Significance Index: -5.0500
Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1600
Cell Significance Index: -3.9900
Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1631
Cell Significance Index: -5.1600
Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.1692
Cell Significance Index: -2.4300
Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1695
Cell Significance Index: -3.4000
Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.1714
Cell Significance Index: -2.8300
Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1772
Cell Significance Index: -4.6600
Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1796
Cell Significance Index: -4.3500
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1803
Cell Significance Index: -6.6200
Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1882
Cell Significance Index: -5.3700
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1924
Cell Significance Index: -6.7600
Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1956
Cell Significance Index: -4.8800
Cell Name: stromal cell (CL0000499)
Fold Change: -0.1962
Cell Significance Index: -2.0100
Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: -0.2093
Cell Significance Index: -2.4300
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2097
Cell Significance Index: -5.6200
Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.2118
Cell Significance Index: -2.9800
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2131
Cell Significance Index: -5.6900
Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.2162
Cell Significance Index: -4.4000
Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2210
Cell Significance Index: -4.6900
Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.2227
Cell Significance Index: -4.4400
Cell Name: thymocyte (CL0000893)
Fold Change: -0.2248
Cell Significance Index: -2.8400
Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2270
Cell Significance Index: -3.8900
Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2347
Cell Significance Index: -5.0700
Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.2378
Cell Significance Index: -4.6800
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.2405
Cell Significance Index: -6.9300
Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2448
Cell Significance Index: -5.8700
Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2453
Cell Significance Index: -5.1200
Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2468
Cell Significance Index: -4.8800
Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.2482
Cell Significance Index: -5.4400
Cell Name: erythrocyte (CL0000232)
Fold Change: -0.2492
Cell Significance Index: -6.3500
Cell Name: keratinocyte (CL0000312)
Fold Change: -0.2542
Cell Significance Index: -6.3500
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2546
Cell Significance Index: -6.9300
Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2607
Cell Significance Index: -2.8400
Cell Name: neuron (CL0000540)
Fold Change: -0.2732
Cell Significance Index: -2.5900
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2744
Cell Significance Index: -6.8600
Cell Name: Mueller cell (CL0000636)
Fold Change: -0.2769
Cell Significance Index: -2.1300
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2807
Cell Significance Index: -3.8300
Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2854
Cell Significance Index: -6.1000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** 1. **Structure**: FGF10 is a single-stranded polypeptide consisting of 164 amino acids, with a molecular weight of approximately 18 kDa. 2. **Expression**: FGF10 is expressed in various tissues, including the cornea, heart, intestine, and brain, and is also found in the plasma and urine. 3. **Function**: FGF10 acts as a potent mitogen, stimulating cell proliferation and migration, and is involved in the regulation of various cellular processes, including differentiation, survival, and angiogenesis. 4. **Receptor binding**: FGF10 binds to the FGF receptors, specifically FGF2 and FGF3, triggering a cascade of signaling pathways that regulate cell growth and differentiation. **Pathways and Functions** FGF10 signaling pathways are involved in various biological processes, including: 1. **Angiogenesis**: FGF10 promotes angiogenesis by stimulating the proliferation and migration of endothelial cells. 2. **Cell differentiation**: FGF10 regulates the differentiation of various cell types, including epithelial cells, endothelial cells, and neural cells. 3. **Growth and development**: FGF10 plays a crucial role in embryonic development, particularly in the formation of the heart, lungs, and limbs. 4. **Tissue regeneration**: FGF10 is involved in tissue regeneration, particularly in the repair of cardiac tissue after injury. 5. **Cancer**: FGF10 is overexpressed in various types of cancer, including breast, lung, and colon cancer, and its dysregulation has been implicated in tumorigenesis. **Clinical Significance** Dysregulation of FGF10 has been implicated in various diseases, including: 1. **Cancer**: FGF10 overexpression has been associated with poor prognosis and aggressive tumor behavior in various types of cancer. 2. **Cardiovascular diseases**: FGF10 dysregulation has been implicated in cardiovascular diseases, including atherosclerosis and cardiac hypertrophy. 3. **Developmental disorders**: FGF10 mutations have been associated with developmental disorders, including congenital heart defects and limb abnormalities. 4. **Neurological disorders**: FGF10 has been implicated in various neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, FGF10 is a multifunctional protein that plays a crucial role in various biological processes, including development, growth, and differentiation. Its dysregulation has been implicated in various diseases, including cancer, cardiovascular diseases, and developmental disorders. Further research is needed to fully understand the mechanisms of FGF10 signaling and its clinical significance.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Fibroblast growth factor 10

Genular Protein ID: 2629450378

Symbol: FGF10_HUMAN

Name: Fibroblast growth factor 10

UniProtKB Accession Codes:

O15520 C7FDY0 Q6FHR3 Q6FHT6 Q96P59

Database IDs:

Citations:

PubMed ID: 9287324

Title: Structure and expression of human fibroblast growth factor-10.

PubMed ID: 9287324

DOI: 10.1074/jbc.272.37.23191

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15806171

Title: The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.

PubMed ID: 15806171

DOI: 10.1038/sj.onc.1208560

PubMed ID: 16597617

Title: Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.

PubMed ID: 16597617

DOI: 10.1074/jbc.m601252200

PubMed ID: 20094046

Title: Fibroblast growth factor signalling: from development to cancer.

PubMed ID: 20094046

DOI: 10.1038/nrc2780

PubMed ID: 12591959

Title: Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.

PubMed ID: 12591959

DOI: 10.1073/pnas.0436500100

PubMed ID: 15654336

Title: Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands.

PubMed ID: 15654336

DOI: 10.1038/ng1507

PubMed ID: 16630169

Title: LADD syndrome is caused by FGF10 mutations.

PubMed ID: 16630169

DOI: 10.1111/j.1399-0004.2006.00597.x

PubMed ID: 16501574

Title: Mutations in different components of FGF signaling in LADD syndrome.

PubMed ID: 16501574

DOI: 10.1038/ng1757

Sequence Information:

Length: 208
Mass: 23436
Checksum: C0A0705C108680B3
Sequence:

MWKWILTHCA SAFPHLPGCC CCCFLLLFLV SSVPVTCQAL GQDMVSPEAT NSSSSSFSSP 
SSAGRHVRSY NHLQGDVRWR KLFSFTKYFL KIEKNGKVSG TKKENCPYSI LEITSVEIGV 
VAVKAINSNY YLAMNKKGKL YGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVAL 
NGKGAPRRGQ KTRRKNTSAH FLPMVVHS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FGF10

Associated with

Cells (max top 100)

Other Information

Structure and expression of human fibroblast growth factor-10. PubMed ID: 9287324

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair. PubMed ID: 15806171

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. PubMed ID: 16597617

Fibroblast growth factor signalling: from development to cancer. PubMed ID: 20094046

Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. PubMed ID: 12591959

Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands. PubMed ID: 15654336

LADD syndrome is caused by FGF10 mutations. PubMed ID: 16630169

Mutations in different components of FGF signaling in LADD syndrome. PubMed ID: 16501574