Details for: GRINA
Gene ID: 2907
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: GRINA
Ensembl ID: ENSG00000178719
Description: glutamate ionotropic receptor NMDA type subunit associated protein 1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 54.12rCSI 49.69%PRS 38.89
-
CSI 28.38rCSI 21.86%PRS 31.4
-
CSI 26.69rCSI 50.38%PRS 41.44
-
CSI 26.26rCSI 43.25%PRS 37.86
-
CSI 22.71rCSI 21.86%PRS 33.77
-
CSI 21.51rCSI 47.51%PRS 24.03
-
CSI 21.23rCSI 26.69%PRS 45.94
-
CSI 17.81rCSI 28.67%PRS 25.73
-
CSI 15.84rCSI 27.94%PRS 40.99
-
CSI 12.38rCSI 19.02%PRS 38.74
-
CSI 12.38rCSI 18.91%PRS 50.64
-
CSI 11.34rCSI 25.45%PRS 54.73
-
CSI 11.33rCSI 15.42%PRS 45.45
-
CSI 10.16rCSI 25.14%PRS 31.21
-
CSI 9.81rCSI 15.73%PRS 64.23
-
CSI 8.75rCSI 12.54%PRS 40.85
-
CSI 8.63rCSI 6.79%PRS 38.7
-
CSI 8.52rCSI 19.02%PRS 38.3
-
CSI 8.46rCSI 8.84%PRS 33.3
-
CSI 8.19rCSI 9.97%PRS 39.74
-
CSI 7.85rCSI 5.48%PRS 34.59
-
CSI 7.74rCSI 6.87%PRS 32.55
-
CSI 7.34rCSI 26.42%PRS 19.84
-
CSI 6.07rCSI 19.69%PRS 37.06
-
CSI 5.75rCSI 6%PRS 33.56
-
CSI 5.64rCSI 14.26%PRS 40.04
-
CSI 5.56rCSI 7.99%PRS 26.27
-
CSI 5.33rCSI 3.82%PRS 44.02
-
CSI 5.19rCSI 9.43%PRS 48.01
-
CSI 5.02rCSI 8.91%PRS 22.27
-
CSI 5rCSI 54.38%PRS 70.11
-
CSI 4.99rCSI 6.15%PRS 63.42
-
CSI 4.65rCSI 6.09%PRS 44.85
-
CSI 4.6rCSI 14.37%PRS 23.57
-
CSI 4.58rCSI 4.91%PRS 30.82
-
CSI 4.49rCSI 8.17%PRS 68.15
-
CSI 4.33rCSI 6.91%PRS 28.18
-
CSI 4.3rCSI 4.57%PRS 48.9
-
CSI 4.14rCSI 3.47%PRS 37.88
-
CSI 4.1rCSI 22.91%PRS 47.85
-
CSI 4.05rCSI 5.18%PRS 71.76
-
CSI 4.04rCSI 2.81%PRS 39.66
-
CSI 4.04rCSI 5.59%PRS 39.91
-
CSI 4.02rCSI 2.98%PRS 45.24
-
CSI 3.99rCSI 9.37%PRS 43.22
-
CSI 3.9rCSI 5.32%PRS 35.67
-
CSI 3.87rCSI 4.93%PRS 37.61
-
CSI 3.8rCSI 3.28%PRS 43.27
-
CSI 3.8rCSI 3.5%PRS 34.07
-
CSI 3.78rCSI 7.6%PRS 24.98
-
CSI 3.75rCSI 5.58%PRS 36.38
-
CSI 3.73rCSI 3.13%PRS 48.81
-
CSI 3.62rCSI 3.02%PRS 59.37
-
CSI 3.59rCSI 4.99%PRS 33.1
-
CSI 3.5rCSI 2.33%PRS 37.29
-
CSI 3.48rCSI 6.91%PRS 33.26
-
CSI 3.45rCSI 6.83%PRS 61.62
-
CSI 3.36rCSI 3.3%PRS 35.11
-
CSI 3.32rCSI 6.01%PRS 59.68
-
CSI 3.31rCSI 7.57%PRS 32.51
-
CSI 3.27rCSI 2.54%PRS 32.54
-
CSI 3.18rCSI 2.63%PRS 33.55
-
CSI 3.18rCSI 4.22%PRS 36.41
-
CSI 3.13rCSI 4.81%PRS 38.65
-
CSI 3.05rCSI 8.06%PRS 38.93
-
CSI 3.05rCSI 3.8%PRS 43.73
-
CSI 3.01rCSI 17.72%PRS 21.94
-
CSI 2.89rCSI 2.88%PRS 28.3
-
CSI 2.89rCSI 4.68%PRS 32.28
-
CSI 2.87rCSI 1.91%PRS 61.12
-
CSI 2.86rCSI 2.31%PRS 33.22
-
CSI 2.86rCSI 2.5%PRS 42.09
-
CSI 2.83rCSI 3.64%PRS 31.51
-
CSI 2.83rCSI 5.35%PRS 57.64
-
CSI 2.82rCSI 5.06%PRS 27.78
-
CSI 2.81rCSI 3.61%PRS 31.04
-
CSI 2.79rCSI 4.5%PRS 43.72
-
CSI 2.77rCSI 4.96%PRS 31.23
-
CSI 2.75rCSI 5.24%PRS 48.86
-
CSI 2.74rCSI 2.78%PRS 79.56
-
CSI 2.74rCSI 2.55%PRS 32.82
-
CSI 2.71rCSI 10.24%PRS 21.65
-
CSI 2.67rCSI 3.65%PRS 44.3
-
CSI 2.64rCSI 2.15%PRS 33.88
-
CSI 2.63rCSI 15.31%PRS 44.54
-
CSI 2.59rCSI 5.7%PRS 36.68
-
CSI 2.58rCSI 15.63%PRS 59.63
-
CSI 2.51rCSI 5.69%PRS 39.56
-
CSI 2.49rCSI 3.64%PRS 35.09
-
CSI 2.48rCSI 5.15%PRS 32.12
-
CSI 2.48rCSI 2.38%PRS 57.3
-
CSI 2.48rCSI 11.43%PRS 56.37
-
CSI 2.44rCSI 2.55%PRS 34.91
-
CSI 2.43rCSI 6.1%PRS 66.48
-
CSI 2.41rCSI 2.11%PRS 37.43
-
CSI 2.4rCSI 2.27%PRS 34.08
-
CSI 2.39rCSI 5.45%PRS 28.38
-
CSI 2.38rCSI 1.97%PRS 31.4
-
CSI 2.37rCSI 11.87%PRS 42.27
-
CSI 2.33rCSI 1.75%PRS 47
-
CSI 0.1rCSI 1.4%PRS 50.4%
-
CSI 0.1rCSI 0.6%PRS 50.6%
-
CSI 0.2rCSI 3.8%PRS 73.4%
-
CSI 0.3rCSI 1.6%PRS 45.2%
-
CSI 0.4rCSI 9.8%PRS 75.4%
-
CSI 0.4rCSI 2.8%PRS 62.3%
-
CSI 0.5rCSI 1.5%PRS 21.8%
-
CSI 0.5rCSI 1.1%PRS 30.6%
-
CSI 0.6rCSI 1.9%PRS 44.5%
-
CSI 0.6rCSI 2.3%PRS 49.2%
-
CSI 0.6rCSI 3.1%PRS 43.0%
-
CSI 0.6rCSI 3.0%PRS 61.8%
-
CSI 0.7rCSI 1.2%PRS 20.2%
-
CSI 0.7rCSI 0.9%PRS 17.9%
-
CSI 0.7rCSI 2.7%PRS 55.9%
-
CSI 0.7rCSI 1.7%PRS 25.7%
-
CSI 0.7rCSI 2.0%PRS 51.7%
-
CSI 0.7rCSI 3.8%PRS 49.6%
-
CSI 0.7rCSI 2.5%PRS 47.2%
-
CSI 0.8rCSI 4.7%PRS 71.0%
-
CSI 0.8rCSI 2.1%PRS 49.0%
-
CSI 0.8rCSI 1.0%PRS 51.4%
-
CSI 0.8rCSI 2.4%PRS 35.8%
-
CSI 0.9rCSI 4.7%PRS 72.7%
-
CSI 0.9rCSI 1.4%PRS 35.8%
-
CSI 0.9rCSI 4.0%PRS 49.6%
-
CSI 0.9rCSI 4.1%PRS 31.7%
-
CSI 1.0rCSI 0.8%PRS 40.8%
-
CSI 1.0rCSI 1.8%PRS 28.6%
-
CSI 1.0rCSI 1.6%PRS 33.6%
-
CSI 1.0rCSI 1.8%PRS 41.9%
-
CSI 1.1rCSI 2.5%PRS 20.3%
-
CSI 1.1rCSI 1.7%PRS 22.6%
-
CSI 1.1rCSI 4.2%PRS 42.5%
-
CSI 1.1rCSI 1.6%PRS 48.6%
-
CSI 1.1rCSI 4.2%PRS 29.4%
-
CSI 1.1rCSI 3.3%PRS 26.5%
-
CSI 1.1rCSI 1.6%PRS 31.5%
-
CSI 1.2rCSI 3.2%PRS 43.7%
-
CSI 1.2rCSI 7.0%PRS 68.7%
-
CSI 1.3rCSI 2.7%PRS 53.9%
-
CSI 1.3rCSI 1.5%PRS 20.7%
-
CSI 1.3rCSI 3.0%PRS 21.4%
-
CSI 1.3rCSI 4.3%PRS 36.4%
-
CSI 1.4rCSI 15.2%PRS 62.3%
-
CSI 1.4rCSI 1.4%PRS 30.8%
-
CSI 1.4rCSI 5.0%PRS 49.5%
-
CSI 1.4rCSI 2.2%PRS 41.3%
-
CSI 1.4rCSI 1.9%PRS 55.1%
-
CSI 1.5rCSI 2.8%PRS 34.2%
-
CSI 1.5rCSI 6.0%PRS 32.7%
-
CSI 1.5rCSI 2.1%PRS 47.8%
-
CSI 1.5rCSI 2.3%PRS 31.2%
-
CSI 1.5rCSI 2.0%PRS 28.4%
-
CSI 1.5rCSI 1.8%PRS 43.6%
-
CSI 1.5rCSI 2.2%PRS 35.7%
-
CSI 1.6rCSI 4.0%PRS 30.9%
-
CSI 1.7rCSI 2.8%PRS 20.9%
-
CSI 1.7rCSI 1.9%PRS 36.5%
-
CSI 1.7rCSI 3.0%PRS 26.6%
-
CSI 1.8rCSI 2.2%PRS 29.4%
-
CSI 1.8rCSI 2.7%PRS 34.1%
-
CSI 1.8rCSI 2.0%PRS 56.4%
-
CSI 1.8rCSI 6.8%PRS 53.5%
-
CSI 1.8rCSI 2.1%PRS 36.6%
-
CSI 1.8rCSI 6.6%PRS 28.0%
-
CSI 1.8rCSI 3.3%PRS 25.0%
-
CSI 1.8rCSI 2.6%PRS 42.7%
-
CSI 1.8rCSI 2.2%PRS 39.3%
-
CSI 1.8rCSI 4.4%PRS 44.2%
-
CSI 1.8rCSI 2.3%PRS 41.5%
-
CSI 1.9rCSI 1.6%PRS 24.5%
-
CSI 1.9rCSI 2.2%PRS 25.0%
-
CSI 1.9rCSI 2.9%PRS 30.6%
-
CSI 1.9rCSI 4.5%PRS 44.8%
-
CSI 1.9rCSI 2.3%PRS 31.7%
-
CSI 1.9rCSI 2.9%PRS 37.1%
-
CSI 1.9rCSI 3.0%PRS 33.3%
-
CSI 2.0rCSI 2.0%PRS 38.2%
-
CSI 2.0rCSI 2.9%PRS 34.7%
-
CSI 2.0rCSI 2.2%PRS 48.3%
-
CSI 2.0rCSI 3.8%PRS 57.1%
-
CSI 2.1rCSI 1.5%PRS 35.5%
-
CSI 2.1rCSI 3.1%PRS 37.1%
-
CSI 2.1rCSI 8.8%PRS 33.0%
-
CSI 2.1rCSI 4.8%PRS 27.2%
-
CSI 2.1rCSI 5.1%PRS 50.5%
-
CSI 2.1rCSI 4.9%PRS 32.6%
-
CSI 2.1rCSI 2.9%PRS 36.9%
-
CSI 2.1rCSI 3.8%PRS 32.1%
-
CSI 2.2rCSI 2.8%PRS 21.5%
-
CSI 2.2rCSI 3.7%PRS 59.0%
-
CSI 2.2rCSI 2.0%PRS 30.3%
-
CSI 2.2rCSI 3.2%PRS 42.4%
-
CSI 2.2rCSI 3.2%PRS 30.6%
-
CSI 2.2rCSI 1.9%PRS 36.4%
-
CSI 2.2rCSI 5.6%PRS 31.1%
-
CSI 2.2rCSI 1.8%PRS 23.2%
-
CSI 2.2rCSI 2.6%PRS 28.8%
-
CSI 2.2rCSI 4.2%PRS 54.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 714598771
Symbol: LFG1_HUMAN
Name: Protein lifeguard 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12761501
Title: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
PubMed ID: 12761501
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8406459
Title: Mapping of the human NMDA receptor subunit (NMDAR1) and the proposed NMDA receptor glutamate-binding subunit (NMDARA1) to chromosomes 9q34.3 and chromosome 8, respectively.
PubMed ID: 8406459
PubMed ID: 19784873
Title: LFG: a candidate apoptosis regulatory gene family.
PubMed ID: 19784873
Sequence Information:
- Length: 371
- Mass: 41203
- Checksum: 62E012DFB0E7DEEB
- Sequence:
MSHEKSFLVS GDNYPPPNPG YPGGPQPPMP PYAQPPYPGA PYPQPPFQPS PYGQPGYPHG PSPYPQGGYP QGPYPQGGYP QGPYPQEGYP QGPYPQGGYP QGPYPQSPFP PNPYGQPQVF PGQDPDSPQH GNYQEEGPPS YYDNQDFPAT NWDDKSIRQA FIRKVFLVLT LQLSVTLSTV SVFTFVAEVK GFVRENVWTY YVSYAVFFIS LIVLSCCGDF RRKHPWNLVA LSVLTASLSY MVGMIASFYN TEAVIMAVGI TTAVCFTVVI FSMQTRYDFT SCMGVLLVSM VVLFIFAILC IFIRNRILEI VYASLGALLF TCFLAVDTQL LLGNKQLSLS PEEYVFAALN LYTDIINIFL YILTIIGRAK E