Details for: TBX22
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
Fold Change: 2.0365
Cell Significance Index: 19.0500 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.5297
Cell Significance Index: 19.3600 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.7276
Cell Significance Index: 17.6300 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.6249
Cell Significance Index: 6.6400 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: 0.3330
Cell Significance Index: 4.3700 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.1997
Cell Significance Index: 2.9100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1323
Cell Significance Index: 15.4200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1297
Cell Significance Index: 7.2800 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.0748
Cell Significance Index: 0.5600 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.0635
Cell Significance Index: 0.5400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0492
Cell Significance Index: 6.3100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0405
Cell Significance Index: 0.5800 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.0217
Cell Significance Index: 0.3100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0143
Cell Significance Index: 0.2400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0039
Cell Significance Index: 0.1000 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: 0.0020
Cell Significance Index: 0.0300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0003
Cell Significance Index: 0.5500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0003
Cell Significance Index: 0.4700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0005
Cell Significance Index: -0.8700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0006
Cell Significance Index: -0.8200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0010
Cell Significance Index: -0.0200 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0011
Cell Significance Index: -0.6200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0014
Cell Significance Index: -0.9200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0018
Cell Significance Index: -1.0200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0019
Cell Significance Index: -1.3600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0021
Cell Significance Index: -1.5700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0021
Cell Significance Index: -1.6300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0022
Cell Significance Index: -1.0100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0027
Cell Significance Index: -0.9700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0031
Cell Significance Index: -0.6200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0034
Cell Significance Index: -0.9700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0061
Cell Significance Index: -0.7000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0063
Cell Significance Index: -1.0700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0074
Cell Significance Index: -1.3300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0075
Cell Significance Index: -1.4800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0078
Cell Significance Index: -1.1300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0083
Cell Significance Index: -1.1400 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0090
Cell Significance Index: -0.2200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0093
Cell Significance Index: -0.2500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0108
Cell Significance Index: -1.3300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0119
Cell Significance Index: -0.3300 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.0121
Cell Significance Index: -0.1200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0132
Cell Significance Index: -1.3700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0154
Cell Significance Index: -0.7200 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.0160
Cell Significance Index: -0.2300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0176
Cell Significance Index: -1.0800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0193
Cell Significance Index: -1.4800 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0198
Cell Significance Index: -0.2500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0202
Cell Significance Index: -1.3600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0230
Cell Significance Index: -0.8000 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0243
Cell Significance Index: -0.2700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0248
Cell Significance Index: -1.6000 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.0257
Cell Significance Index: -0.3600 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0299
Cell Significance Index: -0.2000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0306
Cell Significance Index: -1.4400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0312
Cell Significance Index: -1.0000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0316
Cell Significance Index: -0.9300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0318
Cell Significance Index: -0.8500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0320
Cell Significance Index: -1.6200 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0336
Cell Significance Index: -0.8400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0339
Cell Significance Index: -1.5000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0351
Cell Significance Index: -1.1100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0355
Cell Significance Index: -1.1300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0357
Cell Significance Index: -1.2500 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.0374
Cell Significance Index: -0.4600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0379
Cell Significance Index: -1.2400 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0388
Cell Significance Index: -0.6400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0398
Cell Significance Index: -0.9700 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.0404
Cell Significance Index: -0.5100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0405
Cell Significance Index: -1.6600 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: -0.0414
Cell Significance Index: -0.4400 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: -0.0416
Cell Significance Index: -0.4400 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0420
Cell Significance Index: -0.9700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0425
Cell Significance Index: -1.6100 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.0442
Cell Significance Index: -0.3800 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.0463
Cell Significance Index: -0.2900 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0474
Cell Significance Index: -0.6200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0481
Cell Significance Index: -1.0200 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.0498
Cell Significance Index: -0.5200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0505
Cell Significance Index: -1.2100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0511
Cell Significance Index: -1.0100 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0517
Cell Significance Index: -1.2900 - Cell Name: erythroblast (CL0000765)
Fold Change: -0.0520
Cell Significance Index: -0.6200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0521
Cell Significance Index: -1.1400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0526
Cell Significance Index: -1.5000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0534
Cell Significance Index: -1.5300 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.0540
Cell Significance Index: -0.7200 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: -0.0546
Cell Significance Index: -0.6500 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.0547
Cell Significance Index: -0.7500 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0550
Cell Significance Index: -1.4500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0555
Cell Significance Index: -0.7900 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: -0.0565
Cell Significance Index: -0.4400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0569
Cell Significance Index: -1.1100 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: -0.0572
Cell Significance Index: -0.5400 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0592
Cell Significance Index: -0.7500 - Cell Name: tendon cell (CL0000388)
Fold Change: -0.0625
Cell Significance Index: -0.8500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.0626
Cell Significance Index: -1.0100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0627
Cell Significance Index: -1.3600 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.0632
Cell Significance Index: -0.8100 - Cell Name: osteoblast (CL0000062)
Fold Change: -0.0639
Cell Significance Index: -0.6200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3018252633
Symbol: TBX22_HUMAN
Name: T-box transcription factor TBX22
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11024289
Title: Molecular characterization of a new human T-box gene (TBX22) located in Xq21.1 encoding a protein containing a truncated T-domain.
PubMed ID: 11024289
PubMed ID: 11559848
Title: The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia.
PubMed ID: 11559848
DOI: 10.1038/ng730
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22784330
Title: X-linked CHARGE-like Abruzzo-Erickson syndrome and classic cleft palate with ankyloglossia result from TBX22 splicing mutations.
PubMed ID: 22784330
PubMed ID: 12374769
Title: Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patients.
PubMed ID: 12374769
PubMed ID: 14729838
Title: TBX22 mutations are a frequent cause of cleft palate.
PubMed ID: 14729838
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 23033978
Title: Diagnostic exome sequencing in persons with severe intellectual disability.
PubMed ID: 23033978
Sequence Information:
- Length: 520
- Mass: 57910
- Checksum: 1502E19245CC2C93
- Sequence:
MALSSRARAF SVEALVGRPS KRKLQDPIQA EQPELREKKG GEEEEERRSS AAGKSEPLEK QPKTEPSTSA SSGCGSDSGY GNSSESLEEK DIQMELQGSE LWKRFHDIGT EMIITKAGRR MFPSVRVKVK GLDPGKQYHV AIDVVPVDSK RYRYVYHSSQ WMVAGNTDHL CIIPRFYVHP DSPCSGETWM RQIISFDRMK LTNNEMDDKG HIILQSMHKY KPRVHVIEQG SSVDLSQIQS LPTEGVKTFS FKETEFTTVT AYQNQQITKL KIERNPFAKG FRDTGRNRGV LDGLLETYPW RPSFTLDFKT FGADTQSGSS GSSPVTSSGG APSPLNSLLS PLCFSPMFHL PTSSLGMPCP EAYLPNVNLP LCYKICPTNF WQQQPLVLPA PERLASSNSS QSLAPLMMEV PMLSSLGVTN SKSGSSEDSS DQYLQAPNST NQMLYGLQSP GNIFLPNSIT PEALSCSFHP SYDFYRYNFS MPSRLISGSN HLKVNDDSQV SFGEGKCNHV HWYPAINHYL
Genular Protein ID: 3698519914
Symbol: B3KUL8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 400
- Mass: 44748
- Checksum: DC76A11ADD29E6C3
- Sequence:
MFPSVRVKVK GLDPGKQYHV AIDVVPVDSK RYRYVYHSSQ WMVAGNTDHL CIIPRFYVHP DSPCSGETWM RQIISFDRMK LTNNEMDDKG HIILQSMHKY KPRVHVIEQG SSVDLSQIQS LPTEGVKTFS FKETEFTTVT AYQNQQITKL KIERNPFAKG FRDTGRNRGV LDGLLETYPW RPSFTLDFKT FGADTQSGSS GSSPVTSSGG APSPLNSLLS PLCFSPMFHL PTSSLGMPCP EAYLPNVNLP LCYKICPTNF WQQQPLVLPA PERLASSNSS QSLAPLMMEV PMLSSLGVTN SKSGSSEDSS DQYLQAPNST NQMLYGLQSP GNIFLPNSIT PEALSCSFHP SYDFYRYNFS MPSRLISSSN HLKVNDDSQV SFGEGKCNHV HWYPAINHYL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.