Details for: SLC17A6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 2.6115
Cell Significance Index: 16.9900 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 1.7241
Cell Significance Index: 17.9600 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 0.4947
Cell Significance Index: 4.0500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2709
Cell Significance Index: 54.3400 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.2029
Cell Significance Index: 2.5300 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.1610
Cell Significance Index: 3.9000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0633
Cell Significance Index: 39.5000 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.0194
Cell Significance Index: 0.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0001
Cell Significance Index: -0.0400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.0012
Cell Significance Index: -0.8000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0026
Cell Significance Index: -1.9600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0026
Cell Significance Index: -0.5400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0067
Cell Significance Index: -12.5300 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.0087
Cell Significance Index: -0.1100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0092
Cell Significance Index: -17.0400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0114
Cell Significance Index: -17.5500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0120
Cell Significance Index: -4.3100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0127
Cell Significance Index: -17.2600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0177
Cell Significance Index: -11.2400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0197
Cell Significance Index: -3.3700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0252
Cell Significance Index: -7.2500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0321
Cell Significance Index: -14.5500 - Cell Name: neural cell (CL0002319)
Fold Change: -0.0437
Cell Significance Index: -0.5100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0609
Cell Significance Index: -12.0800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0632
Cell Significance Index: -11.4000 - Cell Name: neuron (CL0000540)
Fold Change: -0.0644
Cell Significance Index: -0.6100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0651
Cell Significance Index: -7.4300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0686
Cell Significance Index: -3.6000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0732
Cell Significance Index: -1.2300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0759
Cell Significance Index: -11.0300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0818
Cell Significance Index: -2.2900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0929
Cell Significance Index: -11.4200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1005
Cell Significance Index: -2.5800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1080
Cell Significance Index: -1.8500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1130
Cell Significance Index: -12.9500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1206
Cell Significance Index: -7.4100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1268
Cell Significance Index: -13.2000 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.1420
Cell Significance Index: -2.1600 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1561
Cell Significance Index: -3.8900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1764
Cell Significance Index: -11.8600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1780
Cell Significance Index: -9.9900 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1955
Cell Significance Index: -2.1300 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.2061
Cell Significance Index: -4.0300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2233
Cell Significance Index: -11.6300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2353
Cell Significance Index: -11.0600 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: -0.2471
Cell Significance Index: -1.9200 - Cell Name: stellate neuron (CL0000122)
Fold Change: -0.2747
Cell Significance Index: -3.1200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2880
Cell Significance Index: -12.7400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3217
Cell Significance Index: -11.2700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3235
Cell Significance Index: -10.5900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3262
Cell Significance Index: -10.3900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3333
Cell Significance Index: -12.6200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3343
Cell Significance Index: -7.3200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.3402
Cell Significance Index: -7.1200 - Cell Name: secretory cell (CL0000151)
Fold Change: -0.3475
Cell Significance Index: -2.4100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.3581
Cell Significance Index: -6.9900 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.3660
Cell Significance Index: -5.3400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3757
Cell Significance Index: -10.7200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.3886
Cell Significance Index: -19.6400 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.3994
Cell Significance Index: -2.7100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4001
Cell Significance Index: -10.7200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.4004
Cell Significance Index: -10.6900 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.4088
Cell Significance Index: -12.9300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.4097
Cell Significance Index: -10.2200 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.4099
Cell Significance Index: -5.3600 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.4215
Cell Significance Index: -5.7800 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.4320
Cell Significance Index: -3.3300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.4320
Cell Significance Index: -17.7000 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: -0.4565
Cell Significance Index: -5.5100 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.4579
Cell Significance Index: -5.9300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.4697
Cell Significance Index: -10.0400 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.4890
Cell Significance Index: -9.9500 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.5059
Cell Significance Index: -12.8900 - Cell Name: retinal astrocyte (CL4033015)
Fold Change: -0.5119
Cell Significance Index: -5.0100 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: -0.5148
Cell Significance Index: -2.7100 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.5191
Cell Significance Index: -6.9200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.5267
Cell Significance Index: -11.3800 - Cell Name: pro-B cell (CL0000826)
Fold Change: -0.5282
Cell Significance Index: -5.6800 - Cell Name: tendon cell (CL0000388)
Fold Change: -0.5295
Cell Significance Index: -7.2000 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.5381
Cell Significance Index: -11.2300 - Cell Name: respiratory basal cell (CL0002633)
Fold Change: -0.5402
Cell Significance Index: -5.3300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.5554
Cell Significance Index: -13.3200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5555
Cell Significance Index: -11.7900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5624
Cell Significance Index: -11.1200 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.5657
Cell Significance Index: -5.8500 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.5700
Cell Significance Index: -5.6400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.5779
Cell Significance Index: -8.5300 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.5884
Cell Significance Index: -11.5800 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: -0.5898
Cell Significance Index: -7.7400 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.5959
Cell Significance Index: -9.8200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.5987
Cell Significance Index: -12.0200 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: -0.5999
Cell Significance Index: -5.4200 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: -0.6036
Cell Significance Index: -6.2600 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.6112
Cell Significance Index: -5.4300 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.6233
Cell Significance Index: -5.9300 - Cell Name: myelocyte (CL0002193)
Fold Change: -0.6261
Cell Significance Index: -6.6900 - Cell Name: immature B cell (CL0000816)
Fold Change: -0.6288
Cell Significance Index: -5.9500 - Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: -0.6313
Cell Significance Index: -6.4900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.6316
Cell Significance Index: -10.6400 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: -0.6321
Cell Significance Index: -7.3200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 547912290
Symbol: VGLU2_HUMAN
Name: Solute carrier family 17 member 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10820226
Title: Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter.
PubMed ID: 10820226
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11698620
Title: Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2).
PubMed ID: 11698620
PubMed ID: 33440152
Title: Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
PubMed ID: 33440152
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 582
- Mass: 64392
- Checksum: CE761E56FA18C6AD
- Sequence:
MESVKQRILA PGKEGLKNFA GKSLGQIYRV LEKKQDTGET IELTEDGKPL EVPERKAPLC DCTCFGLPRR YIIAIMSGLG FCISFGIRCN LGVAIVDMVN NSTIHRGGKV IKEKAKFNWD PETVGMIHGS FFWGYIITQI PGGYIASRLA ANRVFGAAIL LTSTLNMLIP SAARVHYGCV IFVRILQGLV EGVTYPACHG IWSKWAPPLE RSRLATTSFC GSYAGAVIAM PLAGILVQYT GWSSVFYVYG SFGMVWYMFW LLVSYESPAK HPTITDEERR YIEESIGESA NLLGAMEKFK TPWRKFFTSM PVYAIIVANF CRSWTFYLLL ISQPAYFEEV FGFEISKVGM LSAVPHLVMT IIVPIGGQIA DFLRSKQILS TTTVRKIMNC GGFGMEATLL LVVGYSHTRG VAISFLVLAV GFSGFAISGF NVNHLDIAPR YASILMGISN GVGTLSGMVC PIIVGAMTKN KSREEWQYVF LIAALVHYGG VIFYAIFASG EKQPWADPEE TSEEKCGFIH EDELDEETGD ITQNYINYGT TKSYGATTQA NGGWPSGWEK KEEFVQGEVQ DSHSYKDRVD YS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.