Details for: LINC01393

Gene ID: 102724386

Symbol: LINC01393

Ensembl ID: ENSG00000225535

Description: long intergenic non-protein coding RNA 1393

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2967
    Cell Significance Index: 7.9500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.2571
    Cell Significance Index: 3.6600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2398
    Cell Significance Index: 5.2500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1325
    Cell Significance Index: 1.2200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0599
    Cell Significance Index: 1.9000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0445
    Cell Significance Index: 2.3100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0366
    Cell Significance Index: 0.5000
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.0259
    Cell Significance Index: 0.2700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0189
    Cell Significance Index: 3.4000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0096
    Cell Significance Index: 0.2400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0087
    Cell Significance Index: 1.2600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0073
    Cell Significance Index: 0.7500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0065
    Cell Significance Index: 1.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0052
    Cell Significance Index: 1.0500
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.0050
    Cell Significance Index: 0.0600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0050
    Cell Significance Index: 0.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0033
    Cell Significance Index: 0.2500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0010
    Cell Significance Index: 1.3100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0009
    Cell Significance Index: 0.0400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0007
    Cell Significance Index: 0.1300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0006
    Cell Significance Index: 0.8700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0005
    Cell Significance Index: 0.9200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0004
    Cell Significance Index: 0.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0005
    Cell Significance Index: -0.3000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0005
    Cell Significance Index: -0.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0008
    Cell Significance Index: -0.3600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0013
    Cell Significance Index: -0.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0013
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0014
    Cell Significance Index: -1.0700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0017
    Cell Significance Index: -0.9500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0020
    Cell Significance Index: -1.1100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.0024
    Cell Significance Index: -0.0300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0043
    Cell Significance Index: -0.7400
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0045
    Cell Significance Index: -0.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0050
    Cell Significance Index: -0.2800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0051
    Cell Significance Index: -1.0700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0056
    Cell Significance Index: -0.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0058
    Cell Significance Index: -0.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0075
    Cell Significance Index: -1.0300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0076
    Cell Significance Index: -0.8900
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0077
    Cell Significance Index: -0.0900
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0096
    Cell Significance Index: -0.1600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0100
    Cell Significance Index: -1.1800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0103
    Cell Significance Index: -0.4900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0112
    Cell Significance Index: -0.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0119
    Cell Significance Index: -0.9400
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.0130
    Cell Significance Index: -0.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0147
    Cell Significance Index: -0.9900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0150
    Cell Significance Index: -0.4900
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0172
    Cell Significance Index: -0.2200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0194
    Cell Significance Index: -0.6800
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0202
    Cell Significance Index: -0.3400
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0214
    Cell Significance Index: -0.2700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0226
    Cell Significance Index: -1.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0228
    Cell Significance Index: -0.6100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0231
    Cell Significance Index: -0.6800
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0231
    Cell Significance Index: -0.3200
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0243
    Cell Significance Index: -0.3000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0245
    Cell Significance Index: -0.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0246
    Cell Significance Index: -0.9300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0248
    Cell Significance Index: -0.7900
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0249
    Cell Significance Index: -0.2300
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0255
    Cell Significance Index: -0.3500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0259
    Cell Significance Index: -0.9500
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0261
    Cell Significance Index: -0.6700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0261
    Cell Significance Index: -0.5100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0265
    Cell Significance Index: -0.1600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0266
    Cell Significance Index: -0.6500
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0296
    Cell Significance Index: -0.4200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0303
    Cell Significance Index: -0.7800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0305
    Cell Significance Index: -0.7600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0307
    Cell Significance Index: -0.8800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0318
    Cell Significance Index: -0.9400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0327
    Cell Significance Index: -0.4700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0329
    Cell Significance Index: -0.8800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0330
    Cell Significance Index: -0.7000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0344
    Cell Significance Index: -1.2100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0357
    Cell Significance Index: -1.0200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0368
    Cell Significance Index: -0.6200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0375
    Cell Significance Index: -0.8100
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.0376
    Cell Significance Index: -0.3900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0378
    Cell Significance Index: -1.0900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0380
    Cell Significance Index: -0.6100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0388
    Cell Significance Index: -0.9900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0393
    Cell Significance Index: -0.5800
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0394
    Cell Significance Index: -0.6800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0407
    Cell Significance Index: -0.6000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0409
    Cell Significance Index: -0.9800
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0414
    Cell Significance Index: -0.4600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0419
    Cell Significance Index: -0.7300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0419
    Cell Significance Index: -1.1400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0424
    Cell Significance Index: -0.7100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0431
    Cell Significance Index: -0.8700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0440
    Cell Significance Index: -0.8700
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0442
    Cell Significance Index: -0.5600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0443
    Cell Significance Index: -0.4200
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.0452
    Cell Significance Index: -0.3000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0455
    Cell Significance Index: -0.9000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0455
    Cell Significance Index: -0.9500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LINC01393 is a lincRNA, a class of non-coding RNAs that do not encode proteins but regulate gene expression through various mechanisms. Its expression is tightly regulated, and its levels are often correlated with specific cellular processes. One of the notable characteristics of LINC01393 is its ability to interact with various cellular components, including transcription factors, microRNAs, and messenger RNAs (mRNAs). This interaction can modulate gene expression, influencing cellular behavior and fate. **Pathways and Functions:** LINC01393 has been implicated in several signaling pathways, including the Notch, Wnt, and PI3K/AKT pathways, which are crucial for immune cell development, differentiation, and survival. Its expression has been shown to regulate the expression of genes involved in these pathways, thereby influencing the function of immune cells. Specifically, LINC01393 has been found to: * Regulate the expression of Notch ligands, influencing the fate of T cells and B cells * Modulate the Wnt/β-catenin pathway, affecting the proliferation and differentiation of immune cells * Interact with PI3K/AKT signaling, influencing the survival and migration of immune cells **Clinical Significance:** The identification of LINC01393 as a significant player in immune regulation has significant implications for the understanding and treatment of immune-related disorders. Some of the potential clinical applications of LINC01393 include: * **Immunotherapy:** LINC01393 may serve as a novel therapeutic target for cancer treatment, as its expression is often elevated in neoplastic cells. * **Autoimmune diseases:** LINC01393 may play a role in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus, and may serve as a potential therapeutic target. * **Regenerative medicine:** LINC01393 may be involved in the regulation of stem cell fate and differentiation, making it a potential target for regenerative therapies. In conclusion, LINC01393 is a complex lincRNA that plays a significant role in immune regulation and disease. Further research is needed to fully elucidate its mechanisms of action and potential clinical applications. However, the current evidence suggests that LINC01393 is a promising target for the development of novel therapeutic strategies for immune-related disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.