Details for: TRIM67 AS1

Gene ID: 149373

Symbol: TRIM67 AS1

Ensembl ID: ENSG00000235710

Description: TRIM67 antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 2.0268
    Cell Significance Index: 18.9600
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.4016
    Cell Significance Index: 5.2700
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.2683
    Cell Significance Index: 3.9100
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.2566
    Cell Significance Index: 2.6200
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.1887
    Cell Significance Index: 2.7600
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 0.1081
    Cell Significance Index: 0.8900
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.0620
    Cell Significance Index: 0.8100
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.0533
    Cell Significance Index: 0.6300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0521
    Cell Significance Index: 1.1400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.0412
    Cell Significance Index: 0.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0312
    Cell Significance Index: 1.6400
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.0207
    Cell Significance Index: 0.2500
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.0189
    Cell Significance Index: 0.1600
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.0073
    Cell Significance Index: 0.0900
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.0027
    Cell Significance Index: 0.0200
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.0012
    Cell Significance Index: 0.0200
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 0.0009
    Cell Significance Index: 0.0100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0004
    Cell Significance Index: 0.0200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0003
    Cell Significance Index: -0.0900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0004
    Cell Significance Index: -0.1500
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0007
    Cell Significance Index: -0.0100
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0011
    Cell Significance Index: -0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0013
    Cell Significance Index: -0.2600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0022
    Cell Significance Index: -0.0300
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0034
    Cell Significance Index: -0.0400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0035
    Cell Significance Index: -0.0600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0047
    Cell Significance Index: -0.0700
  • Cell Name: interneuron (CL0000099)
    Fold Change: -0.0060
    Cell Significance Index: -0.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0060
    Cell Significance Index: -0.1900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0060
    Cell Significance Index: -0.1500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0061
    Cell Significance Index: -0.1200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0062
    Cell Significance Index: -0.1300
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0066
    Cell Significance Index: -0.1300
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0066
    Cell Significance Index: -0.0800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0069
    Cell Significance Index: -0.0800
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.0075
    Cell Significance Index: -0.0900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0080
    Cell Significance Index: -0.1600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0082
    Cell Significance Index: -0.2200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0083
    Cell Significance Index: -0.1800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0085
    Cell Significance Index: -0.1800
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0093
    Cell Significance Index: -0.0600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0094
    Cell Significance Index: -0.1200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0095
    Cell Significance Index: -0.0900
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0097
    Cell Significance Index: -0.1300
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0108
    Cell Significance Index: -0.1400
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.0108
    Cell Significance Index: -0.1400
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0118
    Cell Significance Index: -0.1500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0124
    Cell Significance Index: -0.3000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0126
    Cell Significance Index: -0.3200
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0126
    Cell Significance Index: -0.1400
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0132
    Cell Significance Index: -0.1400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0133
    Cell Significance Index: -0.1700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0134
    Cell Significance Index: -0.1600
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.0140
    Cell Significance Index: -0.1700
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -0.0148
    Cell Significance Index: -0.1500
  • Cell Name: H1 horizontal cell (CL0004217)
    Fold Change: -0.0151
    Cell Significance Index: -0.1900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0153
    Cell Significance Index: -0.3000
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0157
    Cell Significance Index: -0.1900
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.0157
    Cell Significance Index: -0.1000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0172
    Cell Significance Index: -0.2200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0190
    Cell Significance Index: -0.2400
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0199
    Cell Significance Index: -0.1800
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0206
    Cell Significance Index: -0.1800
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.0211
    Cell Significance Index: -0.2200
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.0212
    Cell Significance Index: -0.2300
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.0225
    Cell Significance Index: -0.2500
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.0225
    Cell Significance Index: -0.2600
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0226
    Cell Significance Index: -0.2600
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0228
    Cell Significance Index: -0.2300
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0230
    Cell Significance Index: -0.3000
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: -0.0230
    Cell Significance Index: -0.2500
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.0236
    Cell Significance Index: -0.2700
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.0243
    Cell Significance Index: -0.1300
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0245
    Cell Significance Index: -0.2800
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0246
    Cell Significance Index: -0.2900
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0247
    Cell Significance Index: -0.1900
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0247
    Cell Significance Index: -0.2600
  • Cell Name: OFF parasol ganglion cell (CL4033051)
    Fold Change: -0.0247
    Cell Significance Index: -0.3100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0247
    Cell Significance Index: -0.3000
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0248
    Cell Significance Index: -0.3100
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: -0.0249
    Cell Significance Index: -0.3000
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.0249
    Cell Significance Index: -0.3100
  • Cell Name: ON parasol ganglion cell (CL4033052)
    Fold Change: -0.0249
    Cell Significance Index: -0.3100
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: -0.0251
    Cell Significance Index: -0.2700
  • Cell Name: invaginating midget bipolar cell (CL4033034)
    Fold Change: -0.0251
    Cell Significance Index: -0.3100
  • Cell Name: diffuse bipolar 2 cell (CL4033028)
    Fold Change: -0.0252
    Cell Significance Index: -0.3100
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0253
    Cell Significance Index: -0.2800
  • Cell Name: H2 horizontal cell (CL0004218)
    Fold Change: -0.0254
    Cell Significance Index: -0.3000
  • Cell Name: diffuse bipolar 4 cell (CL4033031)
    Fold Change: -0.0255
    Cell Significance Index: -0.3100
  • Cell Name: diffuse bipolar 3b cell (CL4033030)
    Fold Change: -0.0257
    Cell Significance Index: -0.3100
  • Cell Name: diffuse bipolar 3a cell (CL4033029)
    Fold Change: -0.0258
    Cell Significance Index: -0.3100
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0261
    Cell Significance Index: -0.3000
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: -0.0261
    Cell Significance Index: -0.3100
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: -0.0261
    Cell Significance Index: -0.1200
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0263
    Cell Significance Index: -0.3100
  • Cell Name: giant bipolar cell (CL4033035)
    Fold Change: -0.0265
    Cell Significance Index: -0.3100
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.0273
    Cell Significance Index: -0.3300
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0273
    Cell Significance Index: -0.2300
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0281
    Cell Significance Index: -0.2600
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0295
    Cell Significance Index: -0.3400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TRIM67 AS1 is a long non-coding RNA (lncRNA) that is antisense to the TRIM67 gene, suggesting a potential regulatory relationship between the two. Its expression is widespread, with significant levels detected in various cell types, including progenitor cells, microglial cells, and neoplastic cells. Notably, TRIM67 AS1 is also expressed in cells of the nervous system, including retina horizontal cells and cerebral cortex GABAergic interneurons. The cellular localization of TRIM67 AS1 is primarily nuclear, although its exact subcellular distribution remains unclear. **Pathways and Functions:** The mechanisms by which TRIM67 AS1 exerts its effects are not well understood. However, several lines of evidence suggest that TRIM67 AS1 may play a role in regulating gene expression, particularly in the context of cellular differentiation and proliferation. Studies have shown that TRIM67 AS1 can interact with its sense partner, TRIM67, to modulate the expression of target genes. This regulatory relationship may involve the enhancement of transcriptional activity or the suppression of gene expression, depending on the cellular context. In addition to its potential role in regulating gene expression, TRIM67 AS1 may also influence cellular signaling pathways. For example, studies have shown that TRIM67 AS1 can interact with microRNAs (miRNAs) to modulate the expression of target genes involved in cellular proliferation and differentiation. Furthermore, TRIM67 AS1 has been implicated in the regulation of cell migration and invasion, processes that are critical in the development and progression of various diseases, including cancer. **Clinical Significance:** The clinical significance of TRIM67 AS1 remains largely unknown, although its expression in neoplastic cells suggests a potential role in tumorigenesis. Further studies are needed to elucidate the mechanisms by which TRIM67 AS1 contributes to cancer development and progression. Additionally, the expression of TRIM67 AS1 in microglial cells and other immune cells may have implications for our understanding of immune-related disorders, such as multiple sclerosis and Alzheimer's disease. In conclusion, TRIM67 AS1 is a complex and enigmatic gene that requires further investigation to fully understand its role in cellular processes. While its expression in various cell types suggests a potential regulatory relationship with its sense partner, TRIM67, the exact mechanisms by which TRIM67 AS1 exerts its effects remain unclear. Further studies are needed to elucidate the clinical significance of TRIM67 AS1 and its potential role in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.