Details for: DPYS
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 5.8509
Cell Significance Index: 49.7300 - Cell Name: plasmablast (CL0000980)
Fold Change: 4.0223
Cell Significance Index: 37.3300 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 3.6278
Cell Significance Index: 9.5700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 2.7468
Cell Significance Index: 46.2700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4916
Cell Significance Index: 296.0200 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.3467
Cell Significance Index: 14.7300 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.8955
Cell Significance Index: 7.1500 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.5342
Cell Significance Index: 8.2700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.4640
Cell Significance Index: 17.5700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.3870
Cell Significance Index: 17.1200 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 0.3677
Cell Significance Index: 1.3900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.3550
Cell Significance Index: 5.2400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2825
Cell Significance Index: 56.6700 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.2388
Cell Significance Index: 1.3800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2080
Cell Significance Index: 74.5900 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.1653
Cell Significance Index: 2.7800 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.1546
Cell Significance Index: 1.3300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0666
Cell Significance Index: 1.9000 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.0517
Cell Significance Index: 0.5100 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: 0.0480
Cell Significance Index: 0.6400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0442
Cell Significance Index: 83.2000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0334
Cell Significance Index: 4.8600 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.0327
Cell Significance Index: 0.2500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.0327
Cell Significance Index: 2.5900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0318
Cell Significance Index: 2.1400 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.0273
Cell Significance Index: 0.2300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0074
Cell Significance Index: 0.9500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0042
Cell Significance Index: 0.0600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0008
Cell Significance Index: 0.4800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0022
Cell Significance Index: -3.4300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0028
Cell Significance Index: -5.2300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0039
Cell Significance Index: -2.8900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0047
Cell Significance Index: -6.3800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0070
Cell Significance Index: -5.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0071
Cell Significance Index: -5.3800 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0073
Cell Significance Index: -0.0800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0087
Cell Significance Index: -5.4200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0094
Cell Significance Index: -5.2800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0098
Cell Significance Index: -5.3400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0119
Cell Significance Index: -5.4200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0125
Cell Significance Index: -3.6000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0157
Cell Significance Index: -1.6000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0223
Cell Significance Index: -0.7100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0255
Cell Significance Index: -5.3700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0263
Cell Significance Index: -4.7400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0264
Cell Significance Index: -4.5100 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: -0.0277
Cell Significance Index: -0.3100 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0292
Cell Significance Index: -0.3900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0312
Cell Significance Index: -3.5800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0339
Cell Significance Index: -0.6700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0390
Cell Significance Index: -5.3600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0400
Cell Significance Index: -1.3100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0416
Cell Significance Index: -5.3800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0420
Cell Significance Index: -5.1700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0430
Cell Significance Index: -4.4800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0531
Cell Significance Index: -0.9100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0599
Cell Significance Index: -4.6000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0702
Cell Significance Index: -2.4600 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.0723
Cell Significance Index: -1.0200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0729
Cell Significance Index: -3.4000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0733
Cell Significance Index: -5.4600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0823
Cell Significance Index: -5.0600 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0833
Cell Significance Index: -3.6200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0862
Cell Significance Index: -2.1500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0904
Cell Significance Index: -4.2500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0934
Cell Significance Index: -5.2400 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0937
Cell Significance Index: -2.3400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0948
Cell Significance Index: -4.9400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1011
Cell Significance Index: -2.7100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1038
Cell Significance Index: -2.9000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1114
Cell Significance Index: -5.8500 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.1123
Cell Significance Index: -1.8500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1165
Cell Significance Index: -5.2800 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: -0.1265
Cell Significance Index: -0.9700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1385
Cell Significance Index: -3.9700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1487
Cell Significance Index: -5.4600 - Cell Name: neuron (CL0000540)
Fold Change: -0.1561
Cell Significance Index: -1.4800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1572
Cell Significance Index: -4.6300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1642
Cell Significance Index: -5.7700 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1671
Cell Significance Index: -1.8200 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.1672
Cell Significance Index: -1.7300 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1729
Cell Significance Index: -4.6300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1758
Cell Significance Index: -6.1100 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1793
Cell Significance Index: -5.6700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1805
Cell Significance Index: -4.6400 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1814
Cell Significance Index: -3.9200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1824
Cell Significance Index: -4.8700 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.1829
Cell Significance Index: -1.7400 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1838
Cell Significance Index: -3.7400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1875
Cell Significance Index: -3.6600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1897
Cell Significance Index: -3.9600 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.1932
Cell Significance Index: -2.6800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1946
Cell Significance Index: -4.1300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1972
Cell Significance Index: -5.1900 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: -0.1988
Cell Significance Index: -1.8900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1996
Cell Significance Index: -5.7500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.2022
Cell Significance Index: -3.9800 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.2040
Cell Significance Index: -1.3800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.2073
Cell Significance Index: -4.3400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2095
Cell Significance Index: -4.2100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1682929951
Symbol: DPYS_HUMAN
Name: Dihydropyrimidinase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8973361
Title: A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.
PubMed ID: 8973361
PubMed ID: 9718352
Title: Dihydropyrimidinase deficiency: structural organization, chromosomal localization, and mutation analysis of the human dihydropyrimidinase gene.
PubMed ID: 9718352
DOI: 10.1086/302022
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 519
- Mass: 56630
- Checksum: 882E33D7C49D6ECC
- Sequence:
MAAPSRLLIR GGRVVNDDFS EVADVLVEDG VVRALGHDLL PPGGAPAGLR VLDAAGKLVL PGGIDTHTHM QFPFMGSRSI DDFHQGTKAA LSGGTTMIID FAIPQKGGSL IEAFETWRSW ADPKVCCDYS LHVAVTWWSD QVKEEMKILV QDKGVNSFKM FMAYKDLYMV TDLELYEAFS RCKEIGAIAQ VHAENGDLIA EGAKKMLALG ITGPEGHELC RPEAVEAEAT LRAITIASAV NCPLYIVHVM SKSAAKVIAD ARRDGKVVYG EPIAASLGTD GTHYWNKEWH HAAHHVMGPP LRPDPSTPDF LMNLLANDDL TTTGTDNCTF NTCQKALGKD DFTKIPNGVN GVEDRMSVIW EKGVHSGKMD ENRFVAVTST NAAKIFNLYP RKGRIAVGSD ADIVIWDPKG TRTISAKTHH QAVNFNIFEG MVCHGVPLVT ISRGKVVYEA GVFSVTAGDG KFIPRKPFAE YIYKRIKQRD RTCTPTPVER APYKGEVATL KSRVTKEDAT AGTRKQAHP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.