Details for: OR7E36P

Gene ID: 26637

Symbol: OR7E36P

Ensembl ID: ENSG00000205240

Description: olfactory receptor family 7 subfamily E member 36 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 3.3268
    Cell Significance Index: 36.0200
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.7053
    Cell Significance Index: 6.9000
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.3080
    Cell Significance Index: 3.0500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0691
    Cell Significance Index: 0.9400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0473
    Cell Significance Index: 0.6800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0247
    Cell Significance Index: 1.1500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0209
    Cell Significance Index: 0.5200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0034
    Cell Significance Index: 0.6800
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 0.0032
    Cell Significance Index: 0.0300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0166
    Cell Significance Index: -0.6100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0235
    Cell Significance Index: -0.7700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0255
    Cell Significance Index: -0.8100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0280
    Cell Significance Index: -0.7500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0303
    Cell Significance Index: -0.7600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0360
    Cell Significance Index: -0.4700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0367
    Cell Significance Index: -0.7800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0370
    Cell Significance Index: -0.8000
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0374
    Cell Significance Index: -0.4800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0411
    Cell Significance Index: -0.7100
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0430
    Cell Significance Index: -0.4000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0445
    Cell Significance Index: -0.8800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0485
    Cell Significance Index: -1.3200
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0495
    Cell Significance Index: -0.6400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0503
    Cell Significance Index: -1.0100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0529
    Cell Significance Index: -0.5400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0530
    Cell Significance Index: -1.3500
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0546
    Cell Significance Index: -0.7500
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0607
    Cell Significance Index: -0.6400
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0677
    Cell Significance Index: -0.5600
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0698
    Cell Significance Index: -0.6300
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0725
    Cell Significance Index: -0.8100
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0854
    Cell Significance Index: -1.0500
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0884
    Cell Significance Index: -1.0600
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0895
    Cell Significance Index: -1.0700
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0907
    Cell Significance Index: -1.0300
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0917
    Cell Significance Index: -1.0200
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0960
    Cell Significance Index: -1.3300
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0964
    Cell Significance Index: -1.1500
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1008
    Cell Significance Index: -1.1900
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1018
    Cell Significance Index: -1.0400
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1035
    Cell Significance Index: -1.2300
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1052
    Cell Significance Index: -1.3800
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: -0.1071
    Cell Significance Index: -1.1800
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: -0.1109
    Cell Significance Index: -0.9200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1130
    Cell Significance Index: -1.3000
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1135
    Cell Significance Index: -1.3800
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.1139
    Cell Significance Index: -1.1800
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1142
    Cell Significance Index: -1.3500
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1176
    Cell Significance Index: -1.5400
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.1186
    Cell Significance Index: -1.2500
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.1191
    Cell Significance Index: -1.4300
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.1191
    Cell Significance Index: -1.4400
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1230
    Cell Significance Index: -1.3500
  • Cell Name: alveolar adventitial fibroblast (CL4028006)
    Fold Change: -0.1242
    Cell Significance Index: -1.3800
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1245
    Cell Significance Index: -1.3500
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.1246
    Cell Significance Index: -1.3800
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1260
    Cell Significance Index: -1.1100
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.1273
    Cell Significance Index: -1.5000
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.1277
    Cell Significance Index: -1.2900
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1293
    Cell Significance Index: -1.4800
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: -0.1293
    Cell Significance Index: -1.3800
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.1303
    Cell Significance Index: -1.3500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.1314
    Cell Significance Index: -1.3600
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1325
    Cell Significance Index: -1.6600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1368
    Cell Significance Index: -1.4900
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1394
    Cell Significance Index: -1.5000
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1417
    Cell Significance Index: -1.3300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1418
    Cell Significance Index: -1.6900
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.1424
    Cell Significance Index: -1.3500
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1436
    Cell Significance Index: -1.6200
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.1439
    Cell Significance Index: -1.3400
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.1464
    Cell Significance Index: -1.2800
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1465
    Cell Significance Index: -1.3700
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: -0.1614
    Cell Significance Index: -1.7800
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1664
    Cell Significance Index: -1.6100
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.1721
    Cell Significance Index: -1.5900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1725
    Cell Significance Index: -1.6400
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.1806
    Cell Significance Index: -1.7400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.2070
    Cell Significance Index: -1.3000
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2192
    Cell Significance Index: -1.3600
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.2197
    Cell Significance Index: -1.6900
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.2320
    Cell Significance Index: -1.3800
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.5192
    Cell Significance Index: -8.9500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Classification:** OR7E36P belongs to the olfactory receptor family 7 subfamily E, a group of genes involved in the detection of odorant molecules in the nose. 2. **Pseudogene status:** Despite its classification as a pseudogene, OR7E36P exhibits significant expression in various cell types, suggesting that it may have evolved to perform alternative functions. 3. **Widespread expression:** OR7E36P has been detected in multiple cell types, including lung ciliated cells, ependymal cells, Bergmann glial cells, and various immune cells, such as plasma cells, CD4-positive T cells, and alpha-beta T cells. 4. **Cellular localization:** OR7E36P is primarily expressed in the cytoplasm, although its subcellular localization and potential membrane-bound activity are unknown. **Pathways and Functions:** Despite its pseudogene status, OR7E36P may be involved in various cellular processes, including: 1. **Immune regulation:** OR7E36P's expression in immune cells suggests that it may play a role in modulating immune responses, potentially influencing the function of T cells and other immune cells. 2. **Cell signaling:** OR7E36P's cytoplasmic expression and potential membrane-bound activity could imply a role in cell signaling pathways, including those involved in immune cell activation and regulation. 3. **Pseudogene-mediated regulation:** As a pseudogene, OR7E36P may exert regulatory effects on gene expression, potentially influencing the function of nearby genes or participating in non-coding RNA-mediated mechanisms. **Clinical Significance:** The OR7E36P gene's involvement in the immune system raises important questions about its potential clinical implications. Some possible areas of investigation include: 1. **Immune-mediated disorders:** OR7E36P's expression in immune cells may contribute to the development of immune-mediated disorders, such as autoimmune diseases or allergies. 2. **Cancer immunotherapy:** OR7E36P's potential role in immune regulation may make it a target for cancer immunotherapy strategies, aimed at enhancing anti-tumor immune responses. 3. **Pseudogene-mediated gene regulation:** Further studies on OR7E36P's regulatory functions may provide insights into the mechanisms of gene expression and the potential impact of pseudogenes on disease pathology. In conclusion, the OR7E36P gene is a fascinating example of a pseudogene that has been found to be significantly expressed in multiple cell types, including those of the immune system. While its functional implications remain unclear, further investigation into OR7E36P's role in immune regulation and cell signaling may uncover new avenues for understanding immune system function and developing novel therapeutic strategies.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.