Details for: CHIA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.8274
Cell Significance Index: 11.4800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.8052
Cell Significance Index: 19.5100 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.4823
Cell Significance Index: 7.0300 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.4250
Cell Significance Index: 2.1200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.3665
Cell Significance Index: 9.9800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1205
Cell Significance Index: 1.7300 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.0864
Cell Significance Index: 0.1900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0438
Cell Significance Index: 0.7500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0261
Cell Significance Index: 0.2700 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.0191
Cell Significance Index: 0.1700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0179
Cell Significance Index: 13.5500 - Cell Name: parietal cell (CL0000162)
Fold Change: 0.0153
Cell Significance Index: 0.1500 - Cell Name: pulmonary alveolar type 2 cell (CL0002063)
Fold Change: 0.0109
Cell Significance Index: 0.0900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.0055
Cell Significance Index: 0.2400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0052
Cell Significance Index: 0.1400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0044
Cell Significance Index: 0.5200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0044
Cell Significance Index: 2.7300 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.0029
Cell Significance Index: 0.0300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0024
Cell Significance Index: 0.4800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0005
Cell Significance Index: 0.0800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0000
Cell Significance Index: -0.0800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0002
Cell Significance Index: -0.1200 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0004
Cell Significance Index: -0.2100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0004
Cell Significance Index: -0.6900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0006
Cell Significance Index: -0.9000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0007
Cell Significance Index: -0.0800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0007
Cell Significance Index: -0.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0008
Cell Significance Index: -0.1600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0009
Cell Significance Index: -0.5700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0009
Cell Significance Index: -1.1900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0010
Cell Significance Index: -0.5400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0013
Cell Significance Index: -0.1900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0013
Cell Significance Index: -0.3600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0014
Cell Significance Index: -0.5000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0016
Cell Significance Index: -0.7400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0019
Cell Significance Index: -0.3500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0021
Cell Significance Index: -0.2900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0029
Cell Significance Index: -0.6100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0030
Cell Significance Index: -0.3500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0043
Cell Significance Index: -0.4400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0047
Cell Significance Index: -0.2200 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.0053
Cell Significance Index: -0.0500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0056
Cell Significance Index: -0.4400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0065
Cell Significance Index: -0.4000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0065
Cell Significance Index: -0.4400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0066
Cell Significance Index: -0.6900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0067
Cell Significance Index: -0.1500 - Cell Name: mesangial cell (CL0000650)
Fold Change: -0.0095
Cell Significance Index: -0.1200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0122
Cell Significance Index: -0.9400 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0129
Cell Significance Index: -0.1400 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0166
Cell Significance Index: -0.1800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0183
Cell Significance Index: -0.6000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0185
Cell Significance Index: -0.5900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0185
Cell Significance Index: -0.8200 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: -0.0189
Cell Significance Index: -0.1500 - Cell Name: endocrine cell (CL0000163)
Fold Change: -0.0190
Cell Significance Index: -0.2300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0193
Cell Significance Index: -0.5500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0195
Cell Significance Index: -1.1000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0200
Cell Significance Index: -0.7000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0214
Cell Significance Index: -0.6000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0224
Cell Significance Index: -0.5900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0227
Cell Significance Index: -0.8600 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.0234
Cell Significance Index: -0.3000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0241
Cell Significance Index: -0.6000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0241
Cell Significance Index: -0.6200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0247
Cell Significance Index: -0.6600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0264
Cell Significance Index: -1.2400 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.0271
Cell Significance Index: -0.3300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0273
Cell Significance Index: -0.5800 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0276
Cell Significance Index: -0.5800 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0279
Cell Significance Index: -0.7100 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0285
Cell Significance Index: -0.5600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0287
Cell Significance Index: -0.6200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0289
Cell Significance Index: -0.5800 - Cell Name: acinar cell (CL0000622)
Fold Change: -0.0295
Cell Significance Index: -0.3700 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0297
Cell Significance Index: -0.7400 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0298
Cell Significance Index: -0.5900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0299
Cell Significance Index: -1.2300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0300
Cell Significance Index: -1.5100 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: -0.0301
Cell Significance Index: -0.3200 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0309
Cell Significance Index: -0.5200 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.0313
Cell Significance Index: -0.4400 - Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.0318
Cell Significance Index: -0.5200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0321
Cell Significance Index: -0.7700 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.0326
Cell Significance Index: -0.6500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0330
Cell Significance Index: -1.2100 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0335
Cell Significance Index: -0.5000 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.0348
Cell Significance Index: -0.6800 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0349
Cell Significance Index: -0.7100 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0352
Cell Significance Index: -0.4700 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.0353
Cell Significance Index: -0.4700 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.0363
Cell Significance Index: -0.6200 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.0364
Cell Significance Index: -0.6300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0364
Cell Significance Index: -0.7100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0368
Cell Significance Index: -0.6200 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: -0.0372
Cell Significance Index: -0.3500 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: -0.0372
Cell Significance Index: -0.4200 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0379
Cell Significance Index: -0.5600 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.0382
Cell Significance Index: -0.5300 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0386
Cell Significance Index: -0.4200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 924193494
Symbol: CHIA_HUMAN
Name: Acidic mammalian chitinase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10548734
Title: Isolation and mapping of a human lung-specific gene, TSA1902, encoding a novel chitinase family member.
PubMed ID: 10548734
PubMed ID: 11085997
Title: Identification of a novel acidic mammalian chitinase distinct from chitotriosidase.
PubMed ID: 11085997
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15192232
Title: Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation.
PubMed ID: 15192232
PubMed ID: 18824549
Title: Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells.
PubMed ID: 18824549
PubMed ID: 19342690
Title: Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism.
PubMed ID: 19342690
PubMed ID: 19241384
Title: Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.
PubMed ID: 19241384
DOI: 10.1002/pro.63
PubMed ID: 19435888
Title: Differential enzymatic activity of common haplotypic versions of the human acidic mammalian chitinase protein.
PubMed ID: 19435888
Sequence Information:
- Length: 476
- Mass: 52271
- Checksum: 92B27BAD2F7EB4CC
- Sequence:
MTKLILLTGL VLILNLQLGS AYQLTCYFTN WAQYRPGLGR FMPDNIDPCL CTHLIYAFAG RQNNEITTIE WNDVTLYQAF NGLKNKNSQL KTLLAIGGWN FGTAPFTAMV STPENRQTFI TSVIKFLRQY EFDGLDFDWE YPGSRGSPPQ DKHLFTVLVQ EMREAFEQEA KQINKPRLMV TAAVAAGISN IQSGYEIPQL SQYLDYIHVM TYDLHGSWEG YTGENSPLYK YPTDTGSNAY LNVDYVMNYW KDNGAPAEKL IVGFPTYGHN FILSNPSNTG IGAPTSGAGP AGPYAKESGI WAYYEICTFL KNGATQGWDA PQEVPYAYQG NVWVGYDNIK SFDIKAQWLK HNKFGGAMVW AIDLDDFTGT FCNQGKFPLI STLKKALGLQ SASCTAPAQP IEPITAAPSG SGNGSGSSSS GGSSGGSGFC AVRANGLYPV ANNRNAFWHC VNGVTYQQNC QAGLVFDTSC DCCNWA
Genular Protein ID: 2406680836
Symbol: Q2VT96_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 430
- Mass: 46616
- Checksum: 27F13917B2B1ECFE
- Sequence:
ETSSSVHEQV ADSGAQAVAF QSGGESSIVW SCPYTEFAAR NSQLKTLLAI GGWNFGTAPF TAMVSTPENR QTFITSVIRF LRQYEFDGLD FDWEYPGSRG SPPQDKHLFT VLVQEMREAF EQEAKQINKP RLMVTAAVAA GISNIQSGYE IPQLSQYLDY IHVMTYDLHG SWEGYTGENS PLYKYPTDTG SNAYLNVDYV MNYWKDNGAP AEKLIVGFPT YGHNFILSNP SNTGIGAPTS GAGPAGPYAK ESGIWAYYEI CTFLKNGATQ GWDAPQEVPY AYQGNVWVGY DNIKSFDIKA QWLKHNKFGG AMVWAIDLDD FTGTFCNQGK FPLISTLKKA LGLQSASCTA PAQPIEPITA APSGSGNGSG SSSSGGSSGG SGFCAVRANG LYPVANNRNA FWHCVNGVTY QQNCQAGLVF DTSCDCCNWA
Genular Protein ID: 165608301
Symbol: A8K3T7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 368
- Mass: 40079
- Checksum: F68BE370DFB687DF
- Sequence:
MVSTPENRQT SITSVIKFLR QYEFDGLDFD WEYPGSRGSP PQDKHLFTVL VQEMREAFEQ EAKQINKPRL MVTAAVAAGI SNIQSGYEIP QLSQYLDYIH VMTYDLHGSW EGYTGENSPL YKYPTDTGSN AYLNVDYVMN YWKDNGAPAE KLIVGFPTYG HNFILSNPSN TGIGAPTSGA GPAGPYAKES GIWAYYEICT FLKNGATQGW DAPQEVPYAY QGNVWVGYDN IKSFDIKAQW LKHNKFGGAM VWAIDLDDFT GTFCNQGKFP LISTLKKALG LQSASCTAPA QPIEPITAAP SGSGNGSGSS SSGGSSGGSG FCAVRANGLY PVANNRNAFW HCVNGVTYQQ NCQAGLVFDT SCDCCNWA
Genular Protein ID: 1169153850
Symbol: Q1M0P3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 315
- Mass: 33763
- Checksum: 9178C22637E268F0
- Sequence:
MREAFEQEAK QINKPRLMVT AAVAAGISNI QSGYEIPQLS QYLDYIHVMT YDLHGSWEGY TGENSPLYKY PTDTGSNAYL NVDYVMNYWK DNGAPAEKLI VGFPTYGHNF ILSNPSNTGI GAPTSGAGPA GPYAKESGIW AYYEICTFLK NGATQGWDAP QEVPYAYQGN VWVGYDNVKS FDIKAQWLKH NKSGGAMVWA IDLDDFTGTF CNQGKFPLIS TLKKALGLQS ASCTAPAQPI EPITAAPSGS GNGSGSSSSG GSSGGSGFCA GRANGLYPVA SNRNAFWHCV NGVTYQQNCQ AGLVFDTSCD CCNWA
Genular Protein ID: 525723742
Symbol: Q1M0P4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 315
- Mass: 33747
- Checksum: FEC71FF721A36023
- Sequence:
MREAFEQEAK QINKPRLMVT AAVAAGISNI QSGYEIPQLS QYLDYVHVMT YDLHGSWEGY TGENSPLYKY PTDTGSNAYL NVDYVMNYWK DNGAPAEKLI VGFPTYGHNF ILSNPSNTGI GAPTSGAGPA GPYAKESGIW AYYEICTFLK NGATQGWDAP QEVPYAYQGN VWAGYDNVKS FDIKAQWLKH NKSGGAMVWA IDLDDFTGTF CNQGKFPLIS TLKKALGLQS ASCTAPAQPI EPITAAPSGS GNGSGSSSSG GSSGGSGFCA GRANGLYPVA NNRNAFWHCV NGVTYQQNCQ AGLVFDTSCD CCNWA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.