Details for: HCRTR1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 2.3166
Cell Significance Index: 39.6000 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.4729
Cell Significance Index: 5.2900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.2787
Cell Significance Index: 6.7500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.2688
Cell Significance Index: 3.8500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.1662
Cell Significance Index: 3.6400 - Cell Name: helper T cell (CL0000912)
Fold Change: 0.1084
Cell Significance Index: 1.5400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0668
Cell Significance Index: 1.7900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0463
Cell Significance Index: 8.3500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.0440
Cell Significance Index: 0.6500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0408
Cell Significance Index: 5.9300 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.0269
Cell Significance Index: 0.3400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.0250
Cell Significance Index: 0.2300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0226
Cell Significance Index: 8.0900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.0174
Cell Significance Index: 0.3600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0165
Cell Significance Index: 3.2700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0068
Cell Significance Index: 0.8400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0067
Cell Significance Index: 1.3500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0035
Cell Significance Index: 6.6800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0002
Cell Significance Index: -0.1400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0002
Cell Significance Index: -0.3500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0009
Cell Significance Index: -1.5700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0014
Cell Significance Index: -0.1100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0014
Cell Significance Index: -1.8600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0024
Cell Significance Index: -1.7800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0029
Cell Significance Index: -1.6000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0030
Cell Significance Index: -1.7000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0035
Cell Significance Index: -1.0200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0038
Cell Significance Index: -1.7300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0038
Cell Significance Index: -0.0500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0067
Cell Significance Index: -0.4100 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.0075
Cell Significance Index: -0.1100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0088
Cell Significance Index: -1.5100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0090
Cell Significance Index: -1.8900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0093
Cell Significance Index: -0.2600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0119
Cell Significance Index: -1.6400 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0122
Cell Significance Index: -0.1600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0126
Cell Significance Index: -1.4500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0126
Cell Significance Index: -0.3300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0147
Cell Significance Index: -0.9900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0159
Cell Significance Index: -1.6600 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: -0.0202
Cell Significance Index: -0.1900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0205
Cell Significance Index: -0.4000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0206
Cell Significance Index: -1.1600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0226
Cell Significance Index: -0.3800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0265
Cell Significance Index: -1.3900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0268
Cell Significance Index: -0.5800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0271
Cell Significance Index: -1.2800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0276
Cell Significance Index: -1.2500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0294
Cell Significance Index: -1.3000 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0303
Cell Significance Index: -0.4400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0312
Cell Significance Index: -0.8500 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.0314
Cell Significance Index: -0.4300 - Cell Name: mesangial cell (CL0000650)
Fold Change: -0.0328
Cell Significance Index: -0.4200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0329
Cell Significance Index: -0.7900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0333
Cell Significance Index: -1.2600 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0356
Cell Significance Index: -0.7000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0357
Cell Significance Index: -1.0300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0363
Cell Significance Index: -1.1900 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0365
Cell Significance Index: -0.9100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0371
Cell Significance Index: -0.9900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0378
Cell Significance Index: -1.0800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0398
Cell Significance Index: -1.4000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0406
Cell Significance Index: -0.8500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0411
Cell Significance Index: -1.3100 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: -0.0434
Cell Significance Index: -0.4500 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0435
Cell Significance Index: -0.6500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0452
Cell Significance Index: -1.2100 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.0461
Cell Significance Index: -0.5900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0462
Cell Significance Index: -0.3100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0469
Cell Significance Index: -1.3800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0473
Cell Significance Index: -0.8100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0475
Cell Significance Index: -1.1600 - Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: -0.0486
Cell Significance Index: -0.5000 - Cell Name: neuroplacodal cell (CL0000032)
Fold Change: -0.0487
Cell Significance Index: -0.6000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0489
Cell Significance Index: -1.7200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0501
Cell Significance Index: -1.2500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0503
Cell Significance Index: -1.0100 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.0507
Cell Significance Index: -0.6500 - Cell Name: neural crest cell (CL0011012)
Fold Change: -0.0525
Cell Significance Index: -0.5700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0530
Cell Significance Index: -1.8400 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0546
Cell Significance Index: -1.3900 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0550
Cell Significance Index: -1.1200 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.0563
Cell Significance Index: -0.7300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0566
Cell Significance Index: -1.1200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0572
Cell Significance Index: -1.6400 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0580
Cell Significance Index: -0.9300 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.0593
Cell Significance Index: -0.7900 - Cell Name: acinar cell (CL0000622)
Fold Change: -0.0597
Cell Significance Index: -0.7500 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0600
Cell Significance Index: -1.0100 - Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.0605
Cell Significance Index: -0.9800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0608
Cell Significance Index: -1.2900 - Cell Name: suprabasal keratinocyte (CL4033013)
Fold Change: -0.0609
Cell Significance Index: -0.9800 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: -0.0611
Cell Significance Index: -0.6200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.0612
Cell Significance Index: -0.8800 - Cell Name: regulatory T cell (CL0000815)
Fold Change: -0.0621
Cell Significance Index: -0.7200 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0625
Cell Significance Index: -0.6900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0627
Cell Significance Index: -1.6500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0636
Cell Significance Index: -2.0100 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.0643
Cell Significance Index: -0.8800 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.0651
Cell Significance Index: -0.8200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4036064441
Symbol: OX1R_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9491897
Title: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
PubMed ID: 9491897
PubMed ID: 10973318
Title: A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains.
PubMed ID: 10973318
DOI: 10.1038/79690
PubMed ID: 11723285
Title: Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.
PubMed ID: 11723285
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11340621
PubMed ID: 11283317
Title: To eat or to sleep? Orexin in the regulation of feeding and wakefulness.
PubMed ID: 11283317
PubMed ID: 26950369
Title: Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
PubMed ID: 26950369
DOI: 10.1038/nsmb.3183
Sequence Information:
- Length: 425
- Mass: 47536
- Checksum: B650B37F3A2CA096
- Sequence:
MEPSATPGAQ MGVPPGSREP SPVPPDYEDE FLRYLWRDYL YPKQYEWVLI AAYVAVFVVA LVGNTLVCLA VWRNHHMRTV TNYFIVNLSL ADVLVTAICL PASLLVDITE SWLFGHALCK VIPYLQAVSV SVAVLTLSFI ALDRWYAICH PLLFKSTARR ARGSILGIWA VSLAIMVPQA AVMECSSVLP ELANRTRLFS VCDERWADDL YPKIYHSCFF IVTYLAPLGL MAMAYFQIFR KLWGRQIPGT TSALVRNWKR PSDQLGDLEQ GLSGEPQPRA RAFLAEVKQM RARRKTAKML MVVLLVFALC YLPISVLNVL KRVFGMFRQA SDREAVYACF TFSHWLVYAN SAANPIIYNF LSGKFREQFK AAFSCCLPGL GPCGSLKAPS PRSSASHKSL SLQSRCSISK ISEHVVLTSV TTVLP
Genular Protein ID: 1345760348
Symbol: A6NMV7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 389
- Mass: 43613
- Checksum: 36DB58EF470D7B13
- Sequence:
MEPSATPGAQ MGVPPGSREP SPVPPDYEDE FLRYLWRDYL YPKQYEWVLI AAYVAVFVVA LVGNTLVCLA VWRNHHMRTV TNYFIVNLSL ADVLVTAICL PASLLVDITE SWLFGHALCK VIPYLQAVSV SVAVLTLSFI ALDRWYAICH PLLFKSTARR ARGSILGIWA VSLAIMVPQA AVMECSSVLP ELANRTRLFS VCDERWADDL YPKIYHSCFF IVTYLAPLGL MAMAYFQIFR KLWGRQIPGT TSALVRNWKR PSDQLGDLEQ GLSGEPQPRA RAFLAEVKQM RARRKTAKML MVVLLVFALC YLPISVLNVL KRVFGMFRQA SDREAVYACF TFSHWLVYAN SAANPIIYNF LSGCKEKSLA LSCPSCPGHD PHLAAALCS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.