Details for: ITGB2

Gene ID: 3689

Symbol: ITGB2

Ensembl ID: ENSG00000160255

Description: integrin subunit beta 2

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 4.53
    Marker Score: 13220
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 4.22
    Marker Score: 3382
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 4.16
    Marker Score: 13120
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.11
    Marker Score: 229615
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.66
    Marker Score: 42578.5
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 3.56
    Marker Score: 3439
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 3.54
    Marker Score: 6906
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 3.52
    Marker Score: 5181
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.45
    Marker Score: 34146
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 3.38
    Marker Score: 4085
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 3.11
    Marker Score: 1343
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 3.01
    Marker Score: 7272
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 3.01
    Marker Score: 1299
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 3
    Marker Score: 3436
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 2.99
    Marker Score: 4120
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 2.95
    Marker Score: 8286
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 2.9
    Marker Score: 7220.5
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.89
    Marker Score: 2430
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 2.79
    Marker Score: 1638
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.79
    Marker Score: 11968
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 2.79
    Marker Score: 917
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 2.74
    Marker Score: 1512
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.7
    Marker Score: 142845
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.64
    Marker Score: 2637
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.61
    Marker Score: 5115
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 2.45
    Marker Score: 622
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 2.44
    Marker Score: 6332
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 2.43
    Marker Score: 2165.5
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 2.41
    Marker Score: 6662
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.39
    Marker Score: 2241
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.35
    Marker Score: 15030
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 2.32
    Marker Score: 581
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 2.25
    Marker Score: 1382
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 2.22
    Marker Score: 1279
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 2.19
    Marker Score: 1607
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 2.19
    Marker Score: 1207
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 2.16
    Marker Score: 18237.5
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.14
    Marker Score: 54769
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.09
    Marker Score: 854
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 2.08
    Marker Score: 12620
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 2.05
    Marker Score: 668
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.05
    Marker Score: 8535
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 2.02
    Marker Score: 2180
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.97
    Marker Score: 2787
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 1.85
    Marker Score: 772
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.84
    Marker Score: 917
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.8
    Marker Score: 558
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 1.74
    Marker Score: 2980
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 1.73
    Marker Score: 393
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.72
    Marker Score: 1250
  • Cell Name: naive T cell (CL0000898)
    Fold Change: 1.7
    Marker Score: 1095
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 1.69
    Marker Score: 1329
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 1.67
    Marker Score: 1152
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.61
    Marker Score: 1637
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 1.57
    Marker Score: 767
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.55
    Marker Score: 1128
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 1.55
    Marker Score: 1285
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 1.54
    Marker Score: 466
  • Cell Name: CD4-positive, CD25-positive, alpha-beta regulatory T cell (CL0000792)
    Fold Change: 1.49
    Marker Score: 395
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 1.46
    Marker Score: 1056
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 1.45
    Marker Score: 346
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.45
    Marker Score: 166852
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.45
    Marker Score: 2525
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 1.43
    Marker Score: 739
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 1.42
    Marker Score: 2535
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: 1.39
    Marker Score: 1537.5
  • Cell Name: macrophage (CL0000235)
    Fold Change: 1.38
    Marker Score: 1540
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.38
    Marker Score: 831
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.37
    Marker Score: 486
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.37
    Marker Score: 4051
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 1.35
    Marker Score: 1189
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 1.33
    Marker Score: 1722
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 1.32
    Marker Score: 1183
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.32
    Marker Score: 2760
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 1.31
    Marker Score: 2957
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.29
    Marker Score: 451
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.28
    Marker Score: 5232
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.26
    Marker Score: 1241
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.24
    Marker Score: 728
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 1.21
    Marker Score: 598
  • Cell Name: monocyte (CL0000576)
    Fold Change: 1.2
    Marker Score: 1559
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.2
    Marker Score: 720
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 1.19
    Marker Score: 1121
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.19
    Marker Score: 590
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.17
    Marker Score: 2125
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 1.17
    Marker Score: 403
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.14
    Marker Score: 758
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 1.14
    Marker Score: 1235
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 1.13
    Marker Score: 876
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 1.13
    Marker Score: 3184
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.13
    Marker Score: 4723
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 1.13
    Marker Score: 685.5
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 1.12
    Marker Score: 951
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 1.1
    Marker Score: 254
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 1.1
    Marker Score: 381
  • Cell Name: Langerhans cell (CL0000453)
    Fold Change: 1.1
    Marker Score: 329
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.1
    Marker Score: 547
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 1.1
    Marker Score: 751
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.06
    Marker Score: 802
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.06
    Marker Score: 341

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Other Information

**Key characteristics:** * ITGB2 is a transmembrane protein with a molecular weight of approximately 120 kDa. * It is a glycoprotein that is expressed in various cell types, including lymphocytes, macrophages, and endothelial cells. * ITGB2 is a key receptor for the cytokine interleukin-4 (IL-4), which is a key cytokine in the regulation of immune responses. * ITGB2 is also a receptor for the cytokine interleukin-13 (IL-13), which is important for the differentiation and activation of dendritic cells. **Pathways and functions:** * ITGB2 is involved in a variety of immune pathways, including the adaptive immune response, the innate immune response, and the regulation of inflammation. * In the adaptive immune response, ITGB2 is expressed on NKp46 cells and other immune cells. ITGB2 binds to the cytokine IL-4, which is expressed on activated T cells and B cells. This binding triggers a signaling cascade that leads to the activation of NKp46 cells and the inhibition of T cells. * In the innate immune response, ITGB2 is expressed on macrophages and dendritic cells. ITGB2 binds to the cytokine IL-4, which promotes the differentiation and activation of macrophages and dendritic cells. * ITGB2 also plays a role in the regulation of inflammation. It is expressed on immune cells and is important for the recruitment of immune cells to sites of inflammation. **Clinical significance:** ITGB2 is a promising target for the treatment of immune disorders. Mutations in ITGB2 have been linked to a number of autoimmune diseases, including rheumatoid arthritis, Crohn's disease, and psoriasis. These mutations can lead to the loss of ITGB2 function, which can result in the activation of immune cells and the development of inflammatory diseases. **Additional information:** * ITGB2 is a highly conserved protein, with similar sequences found in mammals, birds, and fish. * It is a member of the integrin family of cell adhesion molecules, which are expressed in a variety of cell types. * ITGB2 is a key receptor for the cytokine IL-4, which is a key cytokine in the regulation of immune responses. * ITGB2 is also a receptor for the cytokine IL-13, which is important for the differentiation and activation of dendritic cells.

Genular Protein ID: 1330947838

Symbol: ITB2_HUMAN

Name: Integrin beta-2

UniProtKB Accession Codes:

P05107 B3KTS8 D3DSM1 Q16418 Q53HS5 Q9UD72

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugCentral 1 ELM 1 EMBL 25 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 52 Gene3D 6 GeneCards 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 40 PDBsum 23 PIR 1 PIRSF 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 3 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3028646

Title: Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family.

PubMed ID: 3028646

DOI: 10.1016/0092-8674(87)90246-7

PubMed ID: 1683838

Title: The gene organisation of the human beta 2 integrin subunit (CD18).

PubMed ID: 1683838

DOI: 10.1016/0014-5793(91)81351-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2954816

Title: The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor.

PubMed ID: 2954816

DOI: 10.1002/j.1460-2075.1987.tb04838.x

PubMed ID: 7509236

Title: Familial genetic defect in a case of leukocyte adhesion deficiency.

PubMed ID: 7509236

DOI: 10.1002/humu.1380020606

PubMed ID: 1346613

Title: Genetic cause of leukocyte adhesion molecule deficiency. Abnormal splicing and a missense mutation in a conserved region of CD18 impair cell surface expression of beta 2 integrins.

PubMed ID: 1346613

DOI: 10.1016/s0021-9258(19)50738-4

PubMed ID: 10766246

Title: Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity.

PubMed ID: 10766246

DOI: 10.1038/35007098

PubMed ID: 11700305

Title: Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes.

PubMed ID: 11700305

DOI: 10.1074/jbc.m106856200

PubMed ID: 11812992

Title: JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes.

PubMed ID: 11812992

DOI: 10.1038/ni755

PubMed ID: 14722085

Title: RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.

PubMed ID: 14722085

DOI: 10.1074/jbc.m313515200

PubMed ID: 15356110

Title: LFA-1 contributes an early signal for NK cell cytotoxicity.

PubMed ID: 15356110

DOI: 10.4049/jimmunol.173.6.3653

PubMed ID: 16301335

Title: Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms.

PubMed ID: 16301335

DOI: 10.1083/jcb.200504016

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 18587400

Title: Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins.

PubMed ID: 18587400

DOI: 10.1038/ni.1628

PubMed ID: 19828450

Title: Identification and characterization of multiple similar ligand-binding repeats in filamin: implication on filamin-mediated receptor clustering and cross-talk.

PubMed ID: 19828450

DOI: 10.1074/jbc.m109.060954

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21193407

Title: Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.

PubMed ID: 21193407

DOI: 10.1074/jbc.m110.171256

PubMed ID: 23775590

Title: Novel role of ICAM3 and LFA-1 in the clearance of apoptotic neutrophils by human macrophages.

PubMed ID: 23775590

DOI: 10.1007/s10495-013-0873-z

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27055590

Title: LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin.

PubMed ID: 27055590

DOI: 10.1016/j.bbrc.2016.04.007

PubMed ID: 28807980

Title: CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation.

PubMed ID: 28807980

DOI: 10.1182/blood-2017-03-768507

PubMed ID: 29100055

Title: Extracellular ISG15 signals cytokine secretion through the LFA-1 integrin receptor.

PubMed ID: 29100055

DOI: 10.1016/j.molcel.2017.10.003

PubMed ID: 20033057

Title: Structure of an integrin with an alphaI domain, complement receptor type 4.

PubMed ID: 20033057

DOI: 10.1038/emboj.2009.367

PubMed ID: 24385486

Title: An internal ligand-bound, metastable state of a leukocyte integrin, alphaXbeta2.

PubMed ID: 24385486

DOI: 10.1083/jcb.201308083

PubMed ID: 1968911

Title: Point mutations impairing cell surface expression of the common beta subunit (CD18) in a patient with leukocyte adhesion molecule (Leu-CAM) deficiency.

PubMed ID: 1968911

DOI: 10.1172/jci114529

PubMed ID: 1694220

Title: Distinct mutations in two patients with leukocyte adhesion deficiency and their functional correlates.

PubMed ID: 1694220

DOI: 10.1084/jem.172.1.335

PubMed ID: 1590804

Title: Leukocyte adhesion deficiency: identification of novel mutations in two Japanese patients with a severe form.

PubMed ID: 1590804

DOI: 10.1016/s0006-291x(05)80047-6

PubMed ID: 1352501

Title: Molecular basis for a severe case of leukocyte adhesion deficiency.

PubMed ID: 1352501

DOI: 10.1002/eji.1830220730

PubMed ID: 1347532

Title: Identification of two molecular defects in a child with leukocyte adherence deficiency.

PubMed ID: 1347532

DOI: 10.1016/s0021-9258(18)42791-3

PubMed ID: 7686755

Title: A point mutation associated with leukocyte adhesion deficiency type 1 of moderate severity.

PubMed ID: 7686755

DOI: 10.1006/bbrc.1993.1712

PubMed ID: 9884339

Title: A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.

PubMed ID: 9884339

DOI: 10.1172/jci3312

PubMed ID: 20529581

Title: A novel point mutation in CD18 causing leukocyte adhesion deficiency in a Chinese patient.

PubMed ID: 20529581

PubMed ID: 20549317

Title: Characterization of 11 new cases of leukocyte adhesion deficiency type 1 with seven novel mutations in the ITGB2 gene.

PubMed ID: 20549317

DOI: 10.1007/s10875-010-9433-2

Sequence Information:

  • Length: 769
  • Mass: 84791
  • Checksum: 0390BD89F1E71E98
  • Sequence:
    • MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLN FTGPGDPDSI 
RCDTRPQLLM RGCAADDIMD PTSLAETQED HNGGQKQLSP QKVTLYLRPG QAAAFNVTFR 
RAKGYPIDLY YLMDLSYSML DDLRNVKKLG GDLLRALNEI TESGRIGFGS FVDKTVLPFV 
NTHPDKLRNP CPNKEKECQP PFAFRHVLKL TNNSNQFQTE VGKQLISGNL DAPEGGLDAM 
MQVAACPEEI GWRNVTRLLV FATDDGFHFA GDGKLGAILT PNDGRCHLED NLYKRSNEFD 
YPSVGQLAHK LAENNIQPIF AVTSRMVKTY EKLTEIIPKS AVGELSEDSS NVVHLIKNAY 
NKLSSRVFLD HNALPDTLKV TYDSFCSNGV THRNQPRGDC DGVQINVPIT FQVKVTATEC 
IQEQSFVIRA LGFTDIVTVQ VLPQCECRCR DQSRDRSLCH GKGFLECGIC RCDTGYIGKN 
CECQTQGRSS QELEGSCRKD NNSIICSGLG DCVCGQCLCH TSDVPGKLIY GQYCECDTIN 
CERYNGQVCG GPGRGLCFCG KCRCHPGFEG SACQCERTTE GCLNPRRVEC SGRGRCRCNV 
CECHSGYQLP LCQECPGCPS PCGKYISCAE CLKFEKGPFG KNCSAACPGL QLSNNPVKGR 
TCKERDSEGC WVAYTLEQQD GMDRYLIYVD ESRECVAGPN IAAIVGGTVA GIVLIGILLL 
VIWKALIHLS DLREYRRFEK EKLKSQWNND NPLFKSATTT VMNPKFAES

Genular Protein ID: 243051150

Symbol: B4E0R1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E0R1

Database IDs:

ARBA 18 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 5 GenomeRNAi 1 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 3 RefSeq 3 RuleBase 1 SAM 2 SMART 6 SMR 1 SUPFAM 4

Sequence Information:

  • Length: 700
  • Mass: 77355
  • Checksum: 212FE992C68B6B89
  • Sequence:
    • MRGCAADDIM DPTSLAETQE DHNGGQKQLS PQKVTLYLRP GQAAAFNVTF RRAKGYPIDL 
YYLMDLSYSM LDDLRNVKKL GGDLLRALNE ITESGRIGFG SFVDKTVLPF VNTHPDKLRN 
PCPNKEKECQ PPFAFRHVLK LTNNSNQFQT EVGKQLISGN LDAPEGGLDA MMQVAACPEE 
IGWRNVTRLL VFATDDGFHF AGDGKLGAIL TPNDGRCHLE DNLYKRSNEF DYPSVGQLAH 
KLAENNIQPI FAVTSRMVKT YEKLTEIIPK SAVGELSEDS SNVVHLIKNA YNKLSSRVFL 
DHNALPDTLK VTYDSFCSNG VTHRNQPRGD CDGVQINVPI TFQVKVTATE CIQEQSFVIR 
ALGFTDIVTV QVLPQCECRC RDQSRDRSLC HGKGFLECGI CRCDTGYIGK NCECQTQGRS 
SQELEGSCRK DNNSIICSGL GDCVCGQCLC HTSDVPGKLI YGQYCECDTI NCERYNGQVC 
GGPGRGLCFC GKCRCHPGFE GSACQCERTT EGCLNPRRVE CSGRGRCRCN VCECHSGYQL 
PLCQECPGCP SPCGKYISCA ECLKFEKGPF GKNCSAACPG LQLSNNPVKG RTCKERDSEG 
CWVAYTLEQQ DGMDRYLIYV DESRECVAGP NIAAIVGGTV AGIVLIGILL LVIWKALIHL 
SDLREYRRFE KEKLKSQWNN DNPLFKSATT TVMNPKFAES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.