Details for: KIR3DL1

Gene ID: 3811

Symbol: KIR3DL1

Ensembl ID: ENSG00000167633

Description: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 3.7043
    Cell Significance Index: 41.4000
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.4270
    Cell Significance Index: 16.8700
  • Cell Name: activated type II NK T cell (CL0000931)
    Fold Change: 0.5351
    Cell Significance Index: 1.3700
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.2650
    Cell Significance Index: 0.7100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2186
    Cell Significance Index: 3.1300
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 0.2147
    Cell Significance Index: 1.2500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1570
    Cell Significance Index: 4.2000
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.0416
    Cell Significance Index: 0.3700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0309
    Cell Significance Index: 1.4500
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.0100
    Cell Significance Index: 0.0800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: 0.0005
    Cell Significance Index: 0.0200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0005
    Cell Significance Index: -0.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.9700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0007
    Cell Significance Index: -1.3000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0008
    Cell Significance Index: -1.1900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0022
    Cell Significance Index: -1.6300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0024
    Cell Significance Index: -1.0800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0030
    Cell Significance Index: -1.9000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0060
    Cell Significance Index: -1.2100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0061
    Cell Significance Index: -1.2100
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0062
    Cell Significance Index: -0.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0073
    Cell Significance Index: -1.0000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0107
    Cell Significance Index: -1.9200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0108
    Cell Significance Index: -0.2800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0125
    Cell Significance Index: -1.8100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0137
    Cell Significance Index: -1.0500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0159
    Cell Significance Index: -1.9500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0171
    Cell Significance Index: -0.2900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0187
    Cell Significance Index: -1.9100
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0191
    Cell Significance Index: -0.2800
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0253
    Cell Significance Index: -0.2800
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0261
    Cell Significance Index: -0.2700
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0275
    Cell Significance Index: -0.3400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0292
    Cell Significance Index: -0.2600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0298
    Cell Significance Index: -1.9200
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0303
    Cell Significance Index: -0.4000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0368
    Cell Significance Index: -1.2900
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0372
    Cell Significance Index: -0.4000
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0379
    Cell Significance Index: -0.5200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0379
    Cell Significance Index: -1.2000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0388
    Cell Significance Index: -0.9400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0403
    Cell Significance Index: -1.3200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0408
    Cell Significance Index: -1.3000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0447
    Cell Significance Index: -0.6600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0467
    Cell Significance Index: -1.1400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0481
    Cell Significance Index: -0.8100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0483
    Cell Significance Index: -0.5700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0494
    Cell Significance Index: -1.3200
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0510
    Cell Significance Index: -1.3000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0533
    Cell Significance Index: -1.3300
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.0564
    Cell Significance Index: -0.6000
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0578
    Cell Significance Index: -0.4200
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.0598
    Cell Significance Index: -0.4300
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0605
    Cell Significance Index: -0.5600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0609
    Cell Significance Index: -1.2700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0611
    Cell Significance Index: -1.3200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0615
    Cell Significance Index: -1.0600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0616
    Cell Significance Index: -1.8100
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0626
    Cell Significance Index: -0.8100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0638
    Cell Significance Index: -1.3600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0642
    Cell Significance Index: -1.2700
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0667
    Cell Significance Index: -1.0800
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0667
    Cell Significance Index: -0.8500
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0674
    Cell Significance Index: -0.7600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0675
    Cell Significance Index: -1.0300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0676
    Cell Significance Index: -1.3200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0702
    Cell Significance Index: -1.4100
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: -0.0707
    Cell Significance Index: -0.5800
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.0723
    Cell Significance Index: -0.7200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0729
    Cell Significance Index: -1.1700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0731
    Cell Significance Index: -1.4300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0732
    Cell Significance Index: -1.0800
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: -0.0756
    Cell Significance Index: -0.7600
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0763
    Cell Significance Index: -0.9800
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0773
    Cell Significance Index: -0.9100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0773
    Cell Significance Index: -1.1100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0784
    Cell Significance Index: -1.0700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0794
    Cell Significance Index: -1.1300
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0795
    Cell Significance Index: -1.1300
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.0803
    Cell Significance Index: -0.6500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0810
    Cell Significance Index: -1.4000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0818
    Cell Significance Index: -1.6100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0818
    Cell Significance Index: -1.0000
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0819
    Cell Significance Index: -1.4000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0822
    Cell Significance Index: -1.1400
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: -0.0829
    Cell Significance Index: -0.8600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0831
    Cell Significance Index: -1.3900
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0833
    Cell Significance Index: -0.7900
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0845
    Cell Significance Index: -1.1400
  • Cell Name: memory T cell (CL0000813)
    Fold Change: -0.0845
    Cell Significance Index: -0.7000
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0858
    Cell Significance Index: -1.1000
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0861
    Cell Significance Index: -1.0300
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0862
    Cell Significance Index: -1.1100
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.0867
    Cell Significance Index: -1.1100
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: -0.0897
    Cell Significance Index: -0.9300
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0897
    Cell Significance Index: -0.9100
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0913
    Cell Significance Index: -1.3300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0920
    Cell Significance Index: -1.7000
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.0930
    Cell Significance Index: -0.8900
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: -0.0933
    Cell Significance Index: -1.0900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** KIR3DL1 is a transmembrane receptor with three extracellular immunoglobulin domains, which are responsible for binding to major histocompatibility complex (MHC) class I molecules. This binding leads to the activation of inhibitory signaling pathways, which ultimately result in the suppression of NK cell activity. KIR3DL1 is also characterized by its long cytoplasmic tail, which contains several immunoreceptor tyrosine-based inhibitory motifs (ITIMs). These motifs are essential for recruiting inhibitory signaling molecules, such as SHP-1 and SHP-2, which further enhance the inhibitory effects of KIR3DL1. **Pathways and Functions:** KIR3DL1 is involved in several key pathways, including: 1. **Natural Killer-Mediated Cytotoxicity:** KIR3DL1 inhibits NK cell activity by binding to MHC class I molecules, which prevents the activation of the NK cell receptor, NKG2D. This inhibition leads to a decrease in the production of cytotoxic granules and the release of cytokines, such as IFN-γ. 2. **Immunoregulatory Interactions:** KIR3DL1 interacts with other immune cells, including dendritic cells and T cells, to modulate the immune response. This interaction can lead to the suppression of immune responses and the promotion of tolerance. 3. **Amyloid-β Binding:** KIR3DL1 has been shown to bind to amyloid-β peptides, which are associated with Alzheimer's disease. This binding may play a role in the regulation of immune responses to amyloid-β. **Clinical Significance:** KIR3DL1 has been implicated in several diseases, including: 1. **Alzheimer's Disease:** Variations in the KIR3DL1 gene have been associated with an increased risk of Alzheimer's disease. This suggests that KIR3DL1 may play a role in the regulation of immune responses to amyloid-β. 2. **Autoimmune Diseases:** KIR3DL1 has been shown to modulate immune responses in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer:** KIR3DL1 has been implicated in the regulation of immune responses to cancer. Variations in the KIR3DL1 gene have been associated with an increased risk of certain types of cancer. In conclusion, KIR3DL1 is a complex receptor that plays a crucial role in regulating the immune response. Its involvement in various disease processes highlights the importance of further research into the mechanisms of KIR3DL1 and its potential as a therapeutic target.

Genular Protein ID: 377094829

Symbol: KI3L1_HUMAN

Name: CD158 antigen-like family member E

UniProtKB Accession Codes:

P43629 O43473 Q14946 Q16541

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 9 Ensembl 9 EvolutionaryTrace 1 ExpressionAtlas 1 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7716543

Title: Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

PubMed ID: 7716543

DOI: 10.1126/science.7716543

PubMed ID: 8777725

Title: Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.

PubMed ID: 8777725

DOI: 10.1016/1074-7613(95)90069-1

PubMed ID: 8760804

Title: The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

PubMed ID: 8760804

DOI: 10.1084/jem.184.2.505

PubMed ID: 7650366

Title: Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes.

PubMed ID: 7650366

PubMed ID: 9430221

Title: Human diversity in killer cell inhibitory receptor genes.

PubMed ID: 9430221

DOI: 10.1016/s1074-7613(00)80394-5

PubMed ID: 8662091

Title: Alternatively spliced forms of human killer inhibitory receptors.

PubMed ID: 8662091

DOI: 10.1007/bf02602590

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 22020283

Title: Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B.

PubMed ID: 22020283

DOI: 10.1038/nature10517

Sequence Information:

  • Length: 444
  • Mass: 49098
  • Checksum: 47DEA12BBAFDEC53
  • Sequence:
    • MSLMVVSMAC VGLFLVQRAG PHMGGQDKPF LSAWPSAVVP RGGHVTLRCH YRHRFNNFML 
YKEDRIHIPI FHGRIFQESF NMSPVTTAHA GNYTCRGSHP HSPTGWSAPS NPVVIMVTGN 
HRKPSLLAHP GPLVKSGERV ILQCWSDIMF EHFFLHKEGI SKDPSRLVGQ IHDGVSKANF 
SIGPMMLALA GTYRCYGSVT HTPYQLSAPS DPLDIVVTGP YEKPSLSAQP GPKVQAGESV 
TLSCSSRSSY DMYHLSREGG AHERRLPAVR KVNRTFQADF PLGPATHGGT YRCFGSFRHS 
PYEWSDPSDP LLVSVTGNPS SSWPSPTEPS SKSGNPRHLH ILIGTSVVII LFILLLFFLL 
HLWCSNKKNA AVMDQEPAGN RTANSEDSDE QDPEEVTYAQ LDHCVFTQRK ITRPSQRPKT 
PPTDTILYTE LPNAKPRSKV VSCP

Genular Protein ID: 3177857429

Symbol: Q8N6C9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N6C9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 14 GO 1 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 SAM 3 SMART 2 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19411600

Title: Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

PubMed ID: 19411600

DOI: 10.1101/gr.085738.108

Sequence Information:

  • Length: 444
  • Mass: 49086
  • Checksum: DD465C0E774AA6D4
  • Sequence:
    • MSLMVVSMAC VGLFLVQRAG PHMGGQDKPF LSAWPSAVVP RGGHVTLRCH YRHRFNNFML 
YKEDRIHVPI FHGRIFQEGF NMSPVTTAHA GNYTCRGSHP HSPTGWSAPS NPMVIMVTGN 
HRKPSLLAHP GPLVKSGERV ILQCWSDIMF EHFFLHKEGI SKDPSRLVGQ IHDGVSKANF 
SIGPMMLALA GTYRCYGSVT HTPYQLSAPS DPLDIVVTGP YEKPSLSAQP GPKVQAGESV 
TLSCSSRSSY DMYHLSREGG AHERRLPAVR KVNRTFQADF PLGPATHGGT YRCFGSFRHS 
PYEWSDPSDP LLVSVTGNPS SSWPSPTEPS SKSGNPRHLH ILIGTSVVII LFILLLFFLL 
HLWCSNKKNA AVMDQEPAGN RTANSEDSDE QDPEEVTYAQ LDHCVFTQRK ITRPSQRPKT 
PPTDTILYTE LPNAKPRSKV VSCP

Genular Protein ID: 2988955348

Symbol: Q6H2G3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6H2G3

Database IDs:

ARBA 2 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 30 Ensembl 5 GO 1 Gene3D 1 HGNC 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 2 SUPFAM 1 UCSC 1

Citations:

PubMed ID: 14607943

Title: Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

PubMed ID: 14607943

PubMed ID: 19411600

Title: Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

PubMed ID: 19411600

DOI: 10.1101/gr.085738.108

Sequence Information:

  • Length: 444
  • Mass: 49112
  • Checksum: C535D7963242A5CE
  • Sequence:
    • MLLMVVSMAC VGFFLVQRAG PHVGGQDKPF LSAWPSAVVP RGGHVTLRCH YRHRFNNFML 
YKEDRIHVPI FHGRLFQESF NMSPVTTAHA GNYTCRGSHP HSPTGWSAPS NPVVIMVTGN 
HRKPSLLAHP GPLVKSGERV ILQCWSDIMF EHFFLHKEGI SKDPSRLVGQ IHDGVSKANF 
SIGPMMLALA GTYRCYGSVT HTPYQLSAPS DPLDIVVTGP YEKPSLSAQP GPKVQAGESV 
TLSCSSRSSY DMYHLSREGG AHERRLPAVR KVNRTFQADF PLGPATHGGT YRCFGSFRHS 
PYEWSDPSDP LLVSVTGNPS SSWPSPTEPS SKSGNPRHLH ILIGTSVVII LFILLLFFLL 
HLWCSNKKNA AVMDQEPAGN RTANSEDSDE QDPEEVTYAQ LDHCVFTQRK ITRPSQRPKT 
PPTDTILYTE LPNAKPRSKV VSCP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.