Details for: PCK1

Gene ID: 5105

Symbol: PCK1

Ensembl ID: ENSG00000124253

Description: phosphoenolpyruvate carboxykinase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 30.8672
    Cell Significance Index: -12.5400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 12.0282
    Cell Significance Index: 202.6200
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 9.9490
    Cell Significance Index: 26.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 4.8742
    Cell Significance Index: 140.4400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.6064
    Cell Significance Index: -12.3400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 3.5574
    Cell Significance Index: 77.0700
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 3.5231
    Cell Significance Index: 13.4900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.5696
    Cell Significance Index: 116.4700
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 2.3907
    Cell Significance Index: 25.9100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 2.2467
    Cell Significance Index: 32.2000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.1189
    Cell Significance Index: 31.7500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 2.0190
    Cell Significance Index: 29.8000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.7998
    Cell Significance Index: 14.3700
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 1.7219
    Cell Significance Index: 17.3700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 1.5467
    Cell Significance Index: 122.5000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.3270
    Cell Significance Index: 1198.1700
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 1.1767
    Cell Significance Index: 9.9200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.9922
    Cell Significance Index: 31.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9760
    Cell Significance Index: 158.7300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.9230
    Cell Significance Index: 15.5300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9127
    Cell Significance Index: 181.1300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.8142
    Cell Significance Index: 17.3400
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.8014
    Cell Significance Index: 4.6200
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.6432
    Cell Significance Index: 2.8000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6163
    Cell Significance Index: 37.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.5769
    Cell Significance Index: 14.4200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5747
    Cell Significance Index: 56.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4114
    Cell Significance Index: 14.4600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.4055
    Cell Significance Index: 297.2800
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.3660
    Cell Significance Index: 3.2000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3487
    Cell Significance Index: 66.3600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.2946
    Cell Significance Index: 4.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2427
    Cell Significance Index: 16.7900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.1905
    Cell Significance Index: 4.6200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1650
    Cell Significance Index: 19.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0959
    Cell Significance Index: 2.5700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0773
    Cell Significance Index: 1.1000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0164
    Cell Significance Index: 0.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0140
    Cell Significance Index: 1.7900
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0026
    Cell Significance Index: 0.0200
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.0016
    Cell Significance Index: 0.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0006
    Cell Significance Index: -0.4400
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0009
    Cell Significance Index: -0.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0011
    Cell Significance Index: -0.6400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0016
    Cell Significance Index: -1.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0030
    Cell Significance Index: -5.6700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0034
    Cell Significance Index: -5.1600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0035
    Cell Significance Index: -6.4600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0051
    Cell Significance Index: -6.9600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0063
    Cell Significance Index: -3.4300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0078
    Cell Significance Index: -5.9300
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.0080
    Cell Significance Index: -0.0300
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.0081
    Cell Significance Index: -0.0500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0084
    Cell Significance Index: -3.8300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0106
    Cell Significance Index: -2.2300
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.0142
    Cell Significance Index: -0.1000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0163
    Cell Significance Index: -10.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0169
    Cell Significance Index: -2.8900
  • Cell Name: urothelial cell (CL0000731)
    Fold Change: -0.0186
    Cell Significance Index: -0.1300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0214
    Cell Significance Index: -2.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0229
    Cell Significance Index: -2.3400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0268
    Cell Significance Index: -1.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0321
    Cell Significance Index: -6.4400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0342
    Cell Significance Index: -9.8300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0349
    Cell Significance Index: -4.7900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0381
    Cell Significance Index: -0.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0392
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0423
    Cell Significance Index: -4.8500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0471
    Cell Significance Index: -0.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0554
    Cell Significance Index: -6.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0559
    Cell Significance Index: -8.1300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0559
    Cell Significance Index: -6.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0570
    Cell Significance Index: -5.9300
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0619
    Cell Significance Index: -0.4500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0626
    Cell Significance Index: -3.1600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0646
    Cell Significance Index: -1.0000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0660
    Cell Significance Index: -11.9000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0718
    Cell Significance Index: -1.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0744
    Cell Significance Index: -2.1900
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: -0.0852
    Cell Significance Index: -0.5000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0855
    Cell Significance Index: -5.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0889
    Cell Significance Index: -10.9300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0915
    Cell Significance Index: -6.1500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0929
    Cell Significance Index: -5.7100
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.1001
    Cell Significance Index: -0.7900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1005
    Cell Significance Index: -7.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1007
    Cell Significance Index: -13.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1088
    Cell Significance Index: -5.7100
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.1141
    Cell Significance Index: -1.4900
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.1306
    Cell Significance Index: -1.4300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1333
    Cell Significance Index: -2.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1374
    Cell Significance Index: -7.7100
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.1380
    Cell Significance Index: -1.3300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1464
    Cell Significance Index: -3.6500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1471
    Cell Significance Index: -6.8600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1579
    Cell Significance Index: -8.2000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.1630
    Cell Significance Index: -2.8100
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.1764
    Cell Significance Index: -1.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1782
    Cell Significance Index: -13.2800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1802
    Cell Significance Index: -2.5800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subcellular localization**: PCK1 is primarily located in the cytosol of liver cells, where it is involved in gluconeogenesis. 2. **Enzymatic activity**: PCK1 catalyzes the conversion of oxaloacetate to phosphoenolpyruvate, a critical step in gluconeogenesis. 3. **Regulation**: PCK1 is regulated by various factors, including glucagon, insulin, and glucocorticoids, which are hormones that modulate glucose metabolism. 4. **Expression**: PCK1 is highly expressed in liver cells, particularly in the periportal region and centrilobular region of hepatocytes. **Pathways and Functions:** 1. **Gluconeogenesis**: PCK1 is a key enzyme in the gluconeogenic pathway, which generates glucose from non-carbohydrate sources. 2. **Glucose homeostasis**: PCK1 plays a critical role in maintaining glucose homeostasis by regulating gluconeogenesis and glycogen synthesis. 3. **Metabolic regulation**: PCK1 is involved in the regulation of various metabolic processes, including lipid metabolism, protein synthesis, and oxidative stress. 4. **Hormonal regulation**: PCK1 is regulated by various hormones, including glucagon, insulin, and glucocorticoids, which modulate glucose metabolism. **Clinical Significance:** 1. **Diabetes**: Abnormalities in PCK1 expression or function have been linked to diabetes, particularly type 2 diabetes. 2. **Fatty liver disease**: PCK1 is overexpressed in fatty liver disease, which is characterized by excessive fat accumulation in liver cells. 3. **Metabolic syndrome**: PCK1 is involved in the regulation of metabolic syndrome, a cluster of conditions that increase the risk of developing type 2 diabetes and cardiovascular disease. 4. **Cancer**: PCK1 is overexpressed in certain types of cancer, including hepatocellular carcinoma, which is linked to glucose metabolism and energy production. In conclusion, PCK1 is a critical enzyme involved in the regulation of gluconeogenesis and metabolic homeostasis. Abnormalities in PCK1 expression or function have been linked to various metabolic disorders, including diabetes and fatty liver disease. Further research is needed to understand the mechanisms by which PCK1 regulates glucose metabolism and to develop novel therapeutic strategies for the treatment of metabolic disorders.

Genular Protein ID: 1461498223

Symbol: PCKGC_HUMAN

Name: N/A

UniProtKB Accession Codes:

P35558 A8K437 B4DT64 Q8TCA3 Q9UJD2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 18 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 EC 1 EMBL 9 Ensembl 1 EvolutionaryTrace 1 GO 46 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 Rhea 7 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8490617

Title: cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young.

PubMed ID: 8490617

DOI: 10.1093/hmg/2.1.1

PubMed ID: 8325643

Title: Phosphoenolpyruvate carboxykinase (GTP): characterization of the human PCK1 gene and localization distal to MODY on chromosome 20.

PubMed ID: 8325643

DOI: 10.1006/geno.1993.1250

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8547315

Title: Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter.

PubMed ID: 8547315

DOI: 10.1016/0167-4781(95)00194-8

PubMed ID: 1656199

Title: Regulation of phosphoenolpyruvate carboxykinase (GTP) gene transcription.

PubMed ID: 1656199

PubMed ID: 20167786

Title: Regulation of cellular metabolism by protein lysine acetylation.

PubMed ID: 20167786

DOI: 10.1126/science.1179689

PubMed ID: 21726808

Title: Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.

PubMed ID: 21726808

DOI: 10.1016/j.molcel.2011.04.028

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30193097

Title: Dynamic acetylation of phosphoenolpyruvate carboxykinase toggles enzyme activity between gluconeogenic and anaplerotic reactions.

PubMed ID: 30193097

DOI: 10.1016/j.molcel.2018.07.031

PubMed ID: 32322062

Title: The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.

PubMed ID: 32322062

DOI: 10.1038/s41586-020-2183-2

PubMed ID: 11851336

Title: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.

PubMed ID: 11851336

DOI: 10.1006/jmbi.2001.5364

PubMed ID: 14552798

Title: X-ray structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-dibenzylxanthines.

PubMed ID: 14552798

DOI: 10.1016/s0960-894x(03)00723-6

PubMed ID: 17532214

Title: C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase.

PubMed ID: 17532214

DOI: 10.1016/j.bmcl.2007.05.013

PubMed ID: 24863970

Title: Three rare diseases in one sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.

PubMed ID: 24863970

DOI: 10.1016/j.ymgme.2014.04.001

PubMed ID: 26971250

Title: Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis.

PubMed ID: 26971250

DOI: 10.1016/j.ymgme.2016.03.001

PubMed ID: 28216384

Title: Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction.

PubMed ID: 28216384

DOI: 10.1016/j.ymgme.2017.02.003

Sequence Information:

  • Length: 622
  • Mass: 69195
  • Checksum: 78D309E0845CC181
  • Sequence:
    • MPPQLQNGLN LSAKVVQGSL DSLPQAVREF LENNAELCQP DHIHICDGSE EENGRLLGQM 
EEEGILRRLK KYDNCWLALT DPRDVARIES KTVIVTQEQR DTVPIPKTGL SQLGRWMSEE 
DFEKAFNARF PGCMKGRTMY VIPFSMGPLG SPLSKIGIEL TDSPYVVASM RIMTRMGTPV 
LEAVGDGEFV KCLHSVGCPL PLQKPLVNNW PCNPELTLIA HLPDRREIIS FGSGYGGNSL 
LGKKCFALRM ASRLAKEEGW LAEHMLILGI TNPEGEKKYL AAAFPSACGK TNLAMMNPSL 
PGWKVECVGD DIAWMKFDAQ GHLRAINPEN GFFGVAPGTS VKTNPNAIKT IQKNTIFTNV 
AETSDGGVYW EGIDEPLASG VTITSWKNKE WSSEDGEPCA HPNSRFCTPA SQCPIIDAAW 
ESPEGVPIEG IIFGGRRPAG VPLVYEALSW QHGVFVGAAM RSEATAAAEH KGKIIMHDPF 
AMRPFFGYNF GKYLAHWLSM AQHPAAKLPK IFHVNWFRKD KEGKFLWPGF GENSRVLEWM 
FNRIDGKAST KLTPIGYIPK EDALNLKGLG HINMMELFSI SKEFWEKEVE DIEKYLEDQV 
NADLPCEIER EILALKQRIS QM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.