Details for: SI

Gene ID: 6476

Symbol: SI

Ensembl ID: ENSG00000090402

Description: sucrase-isomaltase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: precursor cell (CL0011115)
    Fold Change: 23.3766
    Cell Significance Index: 177.2700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 6.6253
    Cell Significance Index: 99.8400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 4.4410
    Cell Significance Index: -2.9800
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 4.3101
    Cell Significance Index: 43.4800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.4809
    Cell Significance Index: 148.9400
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 2.3518
    Cell Significance Index: 16.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.2600
    Cell Significance Index: 102.4400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 2.1599
    Cell Significance Index: 44.8100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0518
    Cell Significance Index: 59.1200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 2.0364
    Cell Significance Index: 43.3700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.9983
    Cell Significance Index: 217.3500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.9273
    Cell Significance Index: 1740.1800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.8962
    Cell Significance Index: 47.4000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.3561
    Cell Significance Index: 20.3200
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 1.2184
    Cell Significance Index: 13.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.9694
    Cell Significance Index: 34.0700
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.8940
    Cell Significance Index: 21.6600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.7988
    Cell Significance Index: 11.4400
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.4422
    Cell Significance Index: 6.4500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1965
    Cell Significance Index: 19.4400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1573
    Cell Significance Index: 29.9400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0654
    Cell Significance Index: 1.1200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.0651
    Cell Significance Index: 1.6200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0193
    Cell Significance Index: 0.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0006
    Cell Significance Index: -1.1300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0006
    Cell Significance Index: -0.9300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0010
    Cell Significance Index: -1.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0012
    Cell Significance Index: -1.5800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0014
    Cell Significance Index: -0.2900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0018
    Cell Significance Index: -0.5200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0035
    Cell Significance Index: -1.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0038
    Cell Significance Index: -2.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0044
    Cell Significance Index: -0.1400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0046
    Cell Significance Index: -2.9000
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0048
    Cell Significance Index: -0.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0050
    Cell Significance Index: -2.8400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0059
    Cell Significance Index: -3.7500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0066
    Cell Significance Index: -2.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0069
    Cell Significance Index: -0.1500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0074
    Cell Significance Index: -1.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0075
    Cell Significance Index: -1.2800
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0083
    Cell Significance Index: -0.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0086
    Cell Significance Index: -1.0000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0137
    Cell Significance Index: -2.8800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0186
    Cell Significance Index: -1.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0212
    Cell Significance Index: -2.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0220
    Cell Significance Index: -3.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0234
    Cell Significance Index: -4.2300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0262
    Cell Significance Index: -2.7300
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0270
    Cell Significance Index: -0.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0299
    Cell Significance Index: -3.6800
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.0301
    Cell Significance Index: -0.3800
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0319
    Cell Significance Index: -0.3300
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0334
    Cell Significance Index: -0.6800
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0337
    Cell Significance Index: -0.2200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0360
    Cell Significance Index: -0.9800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0382
    Cell Significance Index: -2.5700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0388
    Cell Significance Index: -0.6400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0407
    Cell Significance Index: -0.6000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0445
    Cell Significance Index: -1.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0494
    Cell Significance Index: -3.7900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0497
    Cell Significance Index: -0.9700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0511
    Cell Significance Index: -2.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0516
    Cell Significance Index: -1.4400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0520
    Cell Significance Index: -1.3000
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.0586
    Cell Significance Index: -0.5300
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.0599
    Cell Significance Index: -0.3700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0603
    Cell Significance Index: -1.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0604
    Cell Significance Index: -3.7100
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0636
    Cell Significance Index: -2.0100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0642
    Cell Significance Index: -2.8400
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0648
    Cell Significance Index: -0.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0663
    Cell Significance Index: -3.7200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0714
    Cell Significance Index: -1.2000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0753
    Cell Significance Index: -2.8500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0774
    Cell Significance Index: -2.7100
  • Cell Name: peptic cell (CL0000155)
    Fold Change: -0.0776
    Cell Significance Index: -0.6900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0788
    Cell Significance Index: -2.5800
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0797
    Cell Significance Index: -0.8700
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: -0.0812
    Cell Significance Index: -0.7000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0816
    Cell Significance Index: -2.6000
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.0847
    Cell Significance Index: -0.9000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0849
    Cell Significance Index: -4.4200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0853
    Cell Significance Index: -2.4400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0933
    Cell Significance Index: -2.4900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0947
    Cell Significance Index: -2.3100
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0976
    Cell Significance Index: -1.2500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0978
    Cell Significance Index: -2.6200
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0995
    Cell Significance Index: -0.6900
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.1003
    Cell Significance Index: -1.5000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1045
    Cell Significance Index: -4.9100
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.1069
    Cell Significance Index: -0.5600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1122
    Cell Significance Index: -2.8000
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.1131
    Cell Significance Index: -1.1700
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.1145
    Cell Significance Index: -1.5000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1181
    Cell Significance Index: -1.9900
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.1189
    Cell Significance Index: -1.0300
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.1190
    Cell Significance Index: -1.4700
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.1230
    Cell Significance Index: -1.5800
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: -0.1235
    Cell Significance Index: -1.2100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzyme Function:** Sucrase-isomaltase is a glycosidase enzyme that catalyzes the hydrolysis of sucrose and isomaltose into glucose and fructose, respectively. 2. **Expression Patterns:** The SI gene is highly expressed in enterocytes, goblet cells, and Paneth cells of the small intestine, as well as in cardiac endothelial cells and lymphoid lineage-restricted progenitor cells. 3. **Cellular Localization:** The enzyme is primarily localized to the brush border of the small intestine, where it interacts with carbohydrate molecules to facilitate digestion. 4. **Pathway Involvement:** SI is integral to the alpha-1,4-glucosidase activity pathway, which is crucial for carbohydrate digestion and absorption. **Pathways and Functions:** 1. **Alpha-1,4-Glucosidase Activity:** SI is a key player in the alpha-1,4-glucosidase activity pathway, which is responsible for breaking down complex carbohydrates into simpler sugars. 2. **Digestion and Absorption:** The enzyme facilitates the digestion of sucrose and isomaltose, enabling the absorption of essential nutrients, including glucose and fructose. 3. **Carbohydrate Binding:** SI interacts with carbohydrate molecules at the brush border of the small intestine, facilitating the breakdown of complex carbohydrates into simpler sugars. 4. **Golgi Apparatus and Extracellular Exosome:** The enzyme is also involved in the transport of carbohydrates to the Golgi apparatus and extracellular exosome, where they can be further processed and utilized by other cells. **Clinical Significance:** 1. **Intestinal Saccharidase Deficiencies:** Mutations in the SI gene have been linked to various diseases, including intestinal saccharidase deficiencies, which can lead to impaired carbohydrate digestion and absorption. 2. **Carbohydrate Metabolism Disorders:** Dysregulation of the SI gene has also been implicated in carbohydrate metabolism disorders, including diabetes and obesity. 3. **Gastrointestinal Diseases:** SI deficiency has been associated with gastrointestinal diseases, including celiac disease and Crohn's disease, which can lead to impaired nutrient absorption and malnutrition. 4. **Cancer and Inflammation:** The enzyme's involvement in carbohydrate metabolism and immune response makes it an attractive target for cancer research and potential therapeutic interventions. In conclusion, the sucrase-isomaltase gene plays a vital role in carbohydrate digestion and absorption, and its dysregulation has significant implications for human health. Further research is necessary to fully understand the mechanisms underlying SI deficiency and its relationship to various diseases, ultimately leading to the development of effective therapeutic strategies.

Genular Protein ID: 15839856

Symbol: SUIS_HUMAN

Name: Sucrase-isomaltase, intestinal

UniProtKB Accession Codes:

P14410 A2RUC3 Q1JQ80 Q1RMC2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 1 CDD 3 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 4 EMBL 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 4 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1353958

Title: Sequence of the complete cDNA and the 5' structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase.

PubMed ID: 1353958

DOI: 10.1042/bj2850915

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2962903

Title: Isolation of a cDNA probe for a human jejunal brush-border hydrolase, sucrase-isomaltase, and assignment of the gene locus to chromosome 3.

PubMed ID: 2962903

DOI: 10.1016/0378-1119(87)90181-8

PubMed ID: 1677636

Title: Expression of sucrase-isomaltase and dipeptidylpeptidase IV in human small intestine and colon.

PubMed ID: 1677636

DOI: 10.1016/0016-5085(91)90517-o

PubMed ID: 8521865

Title: Phosphorylation of the N-terminal intracellular tail of sucrase-isomaltase by cAMP-dependent protein kinase.

PubMed ID: 8521865

DOI: 10.1111/j.1432-1033.1995.963_3.x

PubMed ID: 20356844

Title: Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.

PubMed ID: 20356844

DOI: 10.1074/jbc.m109.078980

PubMed ID: 8609217

Title: Congenital sucrase-isomaltase deficiency: identification of a glutamine to proline substitution that leads to a transport block of sucrase-isomaltase in a pre-Golgi compartment.

PubMed ID: 8609217

DOI: 10.1172/jci118459

PubMed ID: 10903344

Title: Congenital sucrase-isomaltase deficiency arising from cleavage and secretion of a mutant form of the enzyme.

PubMed ID: 10903344

DOI: 10.1172/jci9677

PubMed ID: 11340066

Title: Molecular basis of aberrant apical protein transport in an intestinal enzyme disorder.

PubMed ID: 11340066

DOI: 10.1074/jbc.c100219200

PubMed ID: 14724820

Title: Congenital sucrase-isomaltase deficiency because of an accumulation of the mutant enzyme in the endoplasmic reticulum.

PubMed ID: 14724820

DOI: 10.1053/j.gastro.2003.09.022

PubMed ID: 16329100

Title: Novel mutations in the human sucrase-isomaltase gene (SI) that cause congenital carbohydrate malabsorption.

PubMed ID: 16329100

DOI: 10.1002/humu.9392

Sequence Information:

  • Length: 1827
  • Mass: 209453
  • Checksum: DCB93F068AEEF83E
  • Sequence:
    • MARKKFSGLE ISLIVLFVIV TIIAIALIVV LATKTPAVDE ISDSTSTPAT TRVTTNPSDS 
GKCPNVLNDP VNVRINCIPE QFPTEGICAQ RGCCWRPWND SLIPWCFFVD NHGYNVQDMT 
TTSIGVEAKL NRIPSPTLFG NDINSVLFTT QNQTPNRFRF KITDPNNRRY EVPHQYVKEF 
TGPTVSDTLY DVKVAQNPFS IQVIRKSNGK TLFDTSIGPL VYSDQYLQIS TRLPSDYIYG 
IGEQVHKRFR HDLSWKTWPI FTRDQLPGDN NNNLYGHQTF FMCIEDTSGK SFGVFLMNSN 
AMEIFIQPTP IVTYRVTGGI LDFYILLGDT PEQVVQQYQQ LVGLPAMPAY WNLGFQLSRW 
NYKSLDVVKE VVRRNREAGI PFDTQVTDID YMEDKKDFTY DQVAFNGLPQ FVQDLHDHGQ 
KYVIILDPAI SIGRRANGTT YATYERGNTQ HVWINESDGS TPIIGEVWPG LTVYPDFTNP 
NCIDWWANEC SIFHQEVQYD GLWIDMNEVS SFIQGSTKGC NVNKLNYPPF TPDILDKLMY 
SKTICMDAVQ NWGKQYDVHS LYGYSMAIAT EQAVQKVFPN KRSFILTRST FAGSGRHAAH 
WLGDNTASWE QMEWSITGML EFSLFGIPLV GADICGFVAE TTEELCRRWM QLGAFYPFSR 
NHNSDGYEHQ DPAFFGQNSL LVKSSRQYLT IRYTLLPFLY TLFYKAHVFG ETVARPVLHE 
FYEDTNSWIE DTEFLWGPAL LITPVLKQGA DTVSAYIPDA IWYDYESGAK RPWRKQRVDM 
YLPADKIGLH LRGGYIIPIQ EPDVTTTASR KNPLGLIVAL GENNTAKGDF FWDDGETKDT 
IQNGNYILYT FSVSNNTLDI VCTHSSYQEG TTLAFQTVKI LGLTDSVTEV RVAENNQPMN 
AHSNFTYDAS NQVLLIADLK LNLGRNFSVQ WNQIFSENER FNCYPDADLA TEQKCTQRGC 
VWRTGSSLSK APECYFPRQD NSYSVNSARY SSMGITADLQ LNTANARIKL PSDPISTLRV 
EVKYHKNDML QFKIYDPQKK RYEVPVPLNI PTTPISTYED RLYDVEIKEN PFGIQIRRRS 
SGRVIWDSWL PGFAFNDQFI QISTRLPSEY IYGFGEVEHT AFKRDLNWNT WGMFTRDQPP 
GYKLNSYGFH PYYMALEEEG NAHGVFLLNS NAMDVTFQPT PALTYRTVGG ILDFYMFLGP 
TPEVATKQYH EVIGHPVMPA YWALGFQLCR YGYANTSEVR ELYDAMVAAN IPYDVQYTDI 
DYMERQLDFT IGEAFQDLPQ FVDKIRGEGM RYIIILDPAI SGNETKTYPA FERGQQNDVF 
VKWPNTNDIC WAKVWPDLPN ITIDKTLTED EAVNASRAHV AFPDFFRTST AEWWAREIVD 
FYNEKMKFDG LWIDMNEPSS FVNGTTTNQC RNDELNYPPY FPELTKRTDG LHFRTICMEA 
EQILSDGTSV LHYDVHNLYG WSQMKPTHDA LQKTTGKRGI VISRSTYPTS GRWGGHWLGD 
NYARWDNMDK SIIGMMEFSL FGMSYTGADI CGFFNNSEYH LCTRWMQLGA FYPYSRNHNI 
ANTRRQDPAS WNETFAEMSR NILNIRYTLL PYFYTQMHEI HANGGTVIRP LLHEFFDEKP 
TWDIFKQFLW GPAFMVTPVL EPYVQTVNAY VPNARWFDYH TGKDIGVRGQ FQTFNASYDT 
INLHVRGGHI LPCQEPAQNT FYSRQKHMKL IVAADDNQMA QGSLFWDDGE SIDTYERDLY 
LSVQFNLNQT TLTSTILKRG YINKSETRLG SLHVWGKGTT PVNAVTLTYN GNKNSLPFNE 
DTTNMILRID LTTHNVTLEE PIEINWS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.