TUBA3C | ENSG00000198033 | NCBI 7278

Details for: TUBA3C

Gene ID: 7278

Symbol: TUBA3C

Ensembl ID: ENSG00000198033

Description: tubulin alpha 3c

Associated with

Activation of ampk downstream of nmdars
(R-HSA-9619483)
Activation of nmda receptors and postsynaptic events
(R-HSA-442755)
Adaptive immune system
(R-HSA-1280218)
Aggrephagy
(R-HSA-9646399)
Antiviral mechanism by ifn-stimulated genes
(R-HSA-1169410)
Asparagine n-linked glycosylation
(R-HSA-446203)
Assembly and cell surface presentation of nmda receptors
(R-HSA-9609736)
Autophagy
(R-HSA-9612973)
Axon guidance
(R-HSA-422475)
Carboxyterminal post-translational modifications of tubulin
(R-HSA-8955332)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Chaperonin-mediated protein folding
(R-HSA-390466)
Cilium assembly
(R-HSA-5617833)
Cooperation of prefoldin and tric/cct in actin and tubulin folding
(R-HSA-389958)
Copi-dependent golgi-to-er retrograde traffic
(R-HSA-6811434)
Copi-independent golgi-to-er retrograde traffic
(R-HSA-6811436)
Copi-mediated anterograde transport
(R-HSA-6807878)
Cytokine signaling in immune system
(R-HSA-1280215)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Er to golgi anterograde transport
(R-HSA-199977)
Factors involved in megakaryocyte development and platelet production
(R-HSA-983231)
Formation of tubulin folding intermediates by cct/tric
(R-HSA-389960)
G2/m transition
(R-HSA-69275)
Gap junction assembly
(R-HSA-190861)
Gap junction trafficking
(R-HSA-190828)
Gap junction trafficking and regulation
(R-HSA-157858)
Golgi-to-er retrograde transport
(R-HSA-8856688)
Hcmv early events
(R-HSA-9609690)
Hcmv infection
(R-HSA-9609646)
Hedgehog 'off' state
(R-HSA-5610787)
Hemostasis
(R-HSA-109582)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-HSA-3371497)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Interferon signaling
(R-HSA-913531)
Intra-golgi and retrograde golgi-to-er traffic
(R-HSA-6811442)
Intraflagellar transport
(R-HSA-5620924)
Kinesins
(R-HSA-983189)
L1cam interactions
(R-HSA-373760)
Macroautophagy
(R-HSA-1632852)
Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Mhc class ii antigen presentation
(R-HSA-2132295)
Microtubule-dependent trafficking of connexons from golgi to the plasma membrane
(R-HSA-190840)
Mitotic anaphase
(R-HSA-68882)
Mitotic g2-g2/m phases
(R-HSA-453274)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
M phase
(R-HSA-68886)
Nervous system development
(R-HSA-9675108)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Nuclear envelope (ne) reassembly
(R-HSA-2995410)
Organelle biogenesis and maintenance
(R-HSA-1852241)
Pkr-mediated signaling
(R-HSA-9833482)
Post-chaperonin tubulin folding pathway
(R-HSA-389977)
Post-translational protein modification
(R-HSA-597592)
Post nmda receptor activation events
(R-HSA-438064)
Prefoldin mediated transfer of substrate to cct/tric
(R-HSA-389957)
Protein folding
(R-HSA-391251)
Recruitment of numa to mitotic centrosomes
(R-HSA-380320)
Recycling pathway of l1
(R-HSA-437239)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Rho gtpases activate iqgaps
(R-HSA-5626467)
Sealing of the nuclear envelope (ne) by escrt-iii
(R-HSA-9668328)
Selective autophagy
(R-HSA-9663891)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by hedgehog
(R-HSA-5358351)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
The role of gtse1 in g2/m progression after g2 checkpoint
(R-HSA-8852276)
Translocation of slc2a4 (glut4) to the plasma membrane
(R-HSA-1445148)
Transmission across chemical synapses
(R-HSA-112315)
Transport of connexons to the plasma membrane
(R-HSA-190872)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Vesicle-mediated transport
(R-HSA-5653656)
Viral infection pathways
(R-HSA-9824446)
Cytoplasm
(GO:0005737)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Metal ion binding
(GO:0046872)
Microtubule
(GO:0005874)
Microtubule cytoskeleton
(GO:0015630)
Microtubule cytoskeleton organization
(GO:0000226)
Mitotic cell cycle
(GO:0000278)
Nucleus
(GO:0005634)
Structural constituent of cytoskeleton
(GO:0005200)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: neural progenitor cell (CL0011020)
Fold Change: 10.2423
Cell Significance Index: 101.3400
Cell Name: germ cell (CL0000586)
Fold Change: 0.7993
Cell Significance Index: 6.0400
Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.7520
Cell Significance Index: 18.2200
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.5632
Cell Significance Index: 5.8300
Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.4508
Cell Significance Index: 6.5700
Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.2783
Cell Significance Index: 3.1100
Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0705
Cell Significance Index: 1.0100
Cell Name: hepatoblast (CL0005026)
Fold Change: 0.0595
Cell Significance Index: 1.0000
Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.0544
Cell Significance Index: 0.7900
Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.0542
Cell Significance Index: 0.6300
Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.0385
Cell Significance Index: 0.4600
Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0152
Cell Significance Index: 0.3800
Cell Name: mesangial cell (CL0000650)
Fold Change: 0.0079
Cell Significance Index: 0.1000
Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.0073
Cell Significance Index: 0.1000
Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.0066
Cell Significance Index: 0.0800
Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0027
Cell Significance Index: 0.3200
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0008
Cell Significance Index: 0.1700
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0002
Cell Significance Index: 0.0700
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0002
Cell Significance Index: -0.4600
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0003
Cell Significance Index: -0.4900
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0003
Cell Significance Index: -0.4600
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0011
Cell Significance Index: -0.4100
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0013
Cell Significance Index: -0.8300
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0013
Cell Significance Index: -0.1500
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0014
Cell Significance Index: -0.6200
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0015
Cell Significance Index: -0.8600
Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0028
Cell Significance Index: -0.5600
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0030
Cell Significance Index: -0.0800
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0031
Cell Significance Index: -0.1500
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0036
Cell Significance Index: -0.6200
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0040
Cell Significance Index: -0.5500
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0042
Cell Significance Index: -0.8800
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0043
Cell Significance Index: -0.7800
Cell Name: glial cell (CL0000125)
Fold Change: -0.0046
Cell Significance Index: -0.0500
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0050
Cell Significance Index: -0.7200
Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: -0.0063
Cell Significance Index: -0.0500
Cell Name: pro-B cell (CL0000826)
Fold Change: -0.0065
Cell Significance Index: -0.0700
Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0067
Cell Significance Index: -0.1300
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0071
Cell Significance Index: -0.7400
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0077
Cell Significance Index: -0.4300
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0077
Cell Significance Index: -0.2100
Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.0093
Cell Significance Index: -0.1300
Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.0094
Cell Significance Index: -0.1600
Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0096
Cell Significance Index: -0.2100
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0107
Cell Significance Index: -0.8200
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0112
Cell Significance Index: -0.7500
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0114
Cell Significance Index: -0.4000
Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.0119
Cell Significance Index: -0.1500
Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.0138
Cell Significance Index: -0.2700
Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0141
Cell Significance Index: -0.3700
Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0145
Cell Significance Index: -0.4600
Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0147
Cell Significance Index: -0.1600
Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: -0.0149
Cell Significance Index: -0.1800
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0153
Cell Significance Index: -0.9400
Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.0158
Cell Significance Index: -0.1500
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0161
Cell Significance Index: -0.4300
Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0164
Cell Significance Index: -0.4000
Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0164
Cell Significance Index: -0.4100
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0167
Cell Significance Index: -0.7400
Cell Name: dendritic cell (CL0000451)
Fold Change: -0.0169
Cell Significance Index: -0.2200
Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0176
Cell Significance Index: -0.5600
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0180
Cell Significance Index: -0.5900
Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.0191
Cell Significance Index: -0.2800
Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0202
Cell Significance Index: -0.4200
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0234
Cell Significance Index: -0.8900
Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.0243
Cell Significance Index: -0.3700
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0246
Cell Significance Index: -0.3500
Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.0248
Cell Significance Index: -0.4000
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0249
Cell Significance Index: -0.7000
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0250
Cell Significance Index: -0.6400
Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0265
Cell Significance Index: -0.6600
Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0267
Cell Significance Index: -0.6800
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0271
Cell Significance Index: -0.3700
Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.0278
Cell Significance Index: -0.4500
Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0281
Cell Significance Index: -0.8000
Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.0286
Cell Significance Index: -0.3600
Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.0290
Cell Significance Index: -0.4400
Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.0296
Cell Significance Index: -0.5900
Cell Name: lung ciliated cell (CL1000271)
Fold Change: -0.0296
Cell Significance Index: -0.2900
Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: -0.0297
Cell Significance Index: -0.3900
Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0305
Cell Significance Index: -0.6600
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0306
Cell Significance Index: -0.9000
Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0306
Cell Significance Index: -0.6500
Cell Name: suprabasal keratinocyte (CL4033013)
Fold Change: -0.0308
Cell Significance Index: -0.5000
Cell Name: precursor B cell (CL0000817)
Fold Change: -0.0309
Cell Significance Index: -0.4000
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0320
Cell Significance Index: -0.8600
Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0329
Cell Significance Index: -0.6600
Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0332
Cell Significance Index: -0.3500
Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0334
Cell Significance Index: -0.6600
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.0334
Cell Significance Index: -0.4300
Cell Name: neutrophil (CL0000775)
Fold Change: -0.0336
Cell Significance Index: -0.4200
Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0336
Cell Significance Index: -0.4400
Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0339
Cell Significance Index: -0.4300
Cell Name: stromal cell (CL0000499)
Fold Change: -0.0343
Cell Significance Index: -0.3500
Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0353
Cell Significance Index: -0.4400
Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0355
Cell Significance Index: -0.4400
Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0361
Cell Significance Index: -0.7100
Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0377
Cell Significance Index: -0.4500
Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0379
Cell Significance Index: -0.5600
Cell Name: mesothelial cell (CL0000077)
Fold Change: -0.0383
Cell Significance Index: -0.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** TUBA3C is a member of the tubulin gene family, which consists of 13 genes that encode for alpha, beta, gamma, and delta subunits of microtubules. The alpha subunits are the most abundant and diverse subunits, and TUBA3C is one of the 13 alpha subunit genes. The gene is located on chromosome 15q24 and is highly conserved across species. TUBA3C is a single exon gene that encodes a 157-amino acid protein. **Pathways and Functions** TUBA3C is involved in various cellular pathways, including: 1. **Activation of AMPK downstream of NMDARs**: TUBA3C is a component of the NMDA receptor complex, which is involved in the activation of AMPK (AMP-activated protein kinase) downstream of NMDARs (N-methyl-D-aspartate receptors). 2. **Assembly and cell surface presentation of NMDA receptors**: TUBA3C is involved in the assembly and cell surface presentation of NMDA receptors, which are critical for synaptic plasticity and learning. 3. **Autophagy**: TUBA3C is involved in the regulation of autophagy, a process by which cells recycle damaged or dysfunctional components. 4. **Mitotic spindle formation**: TUBA3C is involved in the formation of the mitotic spindle, a structure that separates chromosomes during cell division. 5. **Ciliary basal body**: TUBA3C is involved in the assembly and function of the ciliary basal body, a structure that is essential for ciliary motility. 6. **Cytoplasmic organization**: TUBA3C is involved in the organization of the cytoskeleton, which is critical for maintaining cell shape and structure. **Clinical Significance** Dysregulation of TUBA3C has been implicated in various diseases, including: 1. **Neurological disorders**: TUBA3C has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. **Cancer**: TUBA3C has been implicated in the development and progression of various cancers, including breast cancer, lung cancer, and colon cancer. 3. **Immune system disorders**: TUBA3C has been implicated in the pathogenesis of immune system disorders, such as multiple sclerosis and rheumatoid arthritis. 4. **Developmental disorders**: TUBA3C has been implicated in the development of developmental disorders, such as autism spectrum disorder and schizophrenia. In conclusion, TUBA3C is a critical gene that plays a vital role in various cellular processes, including cell division, transport, and signaling. Dysregulation of TUBA3C has been implicated in various diseases, highlighting the importance of further research into the function and regulation of this gene.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Tubulin alpha-3C chain

Genular Protein ID: 2542540467

Symbol: TBA3C_HUMAN

Name: Tubulin alpha-3C chain

UniProtKB Accession Codes:

P0DPH7 A6NJQ0 Q13748 Q5W099 Q6PEY3 Q96F18

Database IDs:

Citations:

PubMed ID: 9465305

Title: Sequence characterization of a newly identified human alpha-tubulin gene (TUBA2).

PubMed ID: 9465305

DOI: 10.1006/geno.1997.5081

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19524510

Title: Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

PubMed ID: 19524510

DOI: 10.1016/j.cell.2009.05.020

PubMed ID: 24906155

Title: Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.

PubMed ID: 24906155

DOI: 10.1016/j.cell.2014.03.061

PubMed ID: 25908662

Title: Mitosis. Microtubule detyrosination guides chromosomes during mitosis.

PubMed ID: 25908662

DOI: 10.1126/science.aaa5175

PubMed ID: 26875866

Title: Graded control of microtubule severing by tubulin glutamylation.

PubMed ID: 26875866

DOI: 10.1016/j.cell.2016.01.019

PubMed ID: 26972003

Title: Alpha-tubulin tyrosination and CLIP-170 phosphorylation regulate the initiation of dynein-driven transport in neurons.

PubMed ID: 26972003

DOI: 10.1016/j.celrep.2016.02.046

PubMed ID: 29146869

Title: Vasohibins encode tubulin detyrosinating activity.

PubMed ID: 29146869

DOI: 10.1126/science.aao5676

PubMed ID: 35482892

Title: Posttranslational modification of microtubules by the MATCAP detyrosinase.

PubMed ID: 35482892

DOI: 10.1126/science.abn6020

Sequence Information:

Length: 450
Mass: 49960
Checksum: 2A78714CBA782D55
Sequence:

MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK 
HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIVDLVLD 
RIRKLADLCT GLQGFLIFHS FGGGTGSGFA SLLMERLSVD YGKKSKLEFA IYPAPQVSTA 
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA 
SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN 
QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP 
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 
AREDLAALEK DYEEVGVDSV EAEAEEGEEY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TUBA3C

Associated with

Cells (max top 100)

Other Information

Sequence characterization of a newly identified human alpha-tubulin gene (TUBA2). PubMed ID: 9465305

The DNA sequence and analysis of human chromosome 13. PubMed ID: 15057823

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. PubMed ID: 19524510

Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase. PubMed ID: 24906155

Mitosis. Microtubule detyrosination guides chromosomes during mitosis. PubMed ID: 25908662

Graded control of microtubule severing by tubulin glutamylation. PubMed ID: 26875866

Alpha-tubulin tyrosination and CLIP-170 phosphorylation regulate the initiation of dynein-driven transport in neurons. PubMed ID: 26972003

Vasohibins encode tubulin detyrosinating activity. PubMed ID: 29146869

Posttranslational modification of microtubules by the MATCAP detyrosinase. PubMed ID: 35482892