Details for: PRY

Gene ID: 9081

Symbol: PRY

Ensembl ID: ENSG00000169789

Description: PTPN13 like Y-linked

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: glial cell (CL0000125)
    Fold Change: 1.1464
    Cell Significance Index: 12.5600
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.0872
    Cell Significance Index: 1.4900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0488
    Cell Significance Index: 0.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0351
    Cell Significance Index: 0.9400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: 0.0157
    Cell Significance Index: 0.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0016
    Cell Significance Index: -0.3200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0034
    Cell Significance Index: -0.1200
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0041
    Cell Significance Index: -0.0500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0047
    Cell Significance Index: -0.3200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0060
    Cell Significance Index: -0.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0075
    Cell Significance Index: -0.2400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0076
    Cell Significance Index: -0.2500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0095
    Cell Significance Index: -0.2400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0100
    Cell Significance Index: -0.2000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0119
    Cell Significance Index: -0.2900
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: -0.0127
    Cell Significance Index: -0.1500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0128
    Cell Significance Index: -0.3200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0141
    Cell Significance Index: -0.3000
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0142
    Cell Significance Index: -0.1700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0156
    Cell Significance Index: -0.3300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0164
    Cell Significance Index: -0.3300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0165
    Cell Significance Index: -0.3300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0167
    Cell Significance Index: -0.3600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0168
    Cell Significance Index: -0.3300
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0205
    Cell Significance Index: -0.2700
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0207
    Cell Significance Index: -0.2700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0214
    Cell Significance Index: -0.2700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0220
    Cell Significance Index: -0.3800
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0226
    Cell Significance Index: -0.3000
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.0227
    Cell Significance Index: -0.2900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0229
    Cell Significance Index: -0.2500
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0241
    Cell Significance Index: -0.2500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0242
    Cell Significance Index: -0.3100
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0250
    Cell Significance Index: -0.3200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0251
    Cell Significance Index: -0.3700
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0254
    Cell Significance Index: -0.2800
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.0257
    Cell Significance Index: -0.2600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0265
    Cell Significance Index: -0.3800
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0271
    Cell Significance Index: -0.3000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0281
    Cell Significance Index: -0.3300
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0284
    Cell Significance Index: -0.4600
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: -0.0285
    Cell Significance Index: -0.2900
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0285
    Cell Significance Index: -0.3000
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0312
    Cell Significance Index: -0.3800
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.0313
    Cell Significance Index: -0.2700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0314
    Cell Significance Index: -0.4500
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0316
    Cell Significance Index: -0.3000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0317
    Cell Significance Index: -0.3400
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0318
    Cell Significance Index: -0.3700
  • Cell Name: smooth muscle cell of the pulmonary artery (CL0002591)
    Fold Change: -0.0318
    Cell Significance Index: -0.2700
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0320
    Cell Significance Index: -0.4100
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0323
    Cell Significance Index: -0.2900
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0324
    Cell Significance Index: -0.2900
  • Cell Name: muscle cell (CL0000187)
    Fold Change: -0.0327
    Cell Significance Index: -0.3100
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0334
    Cell Significance Index: -0.4500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0343
    Cell Significance Index: -0.3300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0369
    Cell Significance Index: -0.4400
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.0379
    Cell Significance Index: -0.4600
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0387
    Cell Significance Index: -0.4700
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0406
    Cell Significance Index: -0.4400
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: -0.0406
    Cell Significance Index: -0.2100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0419
    Cell Significance Index: -0.4800
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.0428
    Cell Significance Index: -0.4600
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0428
    Cell Significance Index: -0.4600
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.0466
    Cell Significance Index: -0.2900
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0527
    Cell Significance Index: -0.5000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0553
    Cell Significance Index: -1.2100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0588
    Cell Significance Index: -1.1500
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0598
    Cell Significance Index: -0.4600
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0602
    Cell Significance Index: -0.8300
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0626
    Cell Significance Index: -0.7700
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0729
    Cell Significance Index: -0.9600
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0847
    Cell Significance Index: -1.2300
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0999
    Cell Significance Index: -1.1800
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.1106
    Cell Significance Index: -1.1300
  • Cell Name: platelet (CL0000233)
    Fold Change: -0.1128
    Cell Significance Index: -1.1600
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.1232
    Cell Significance Index: -1.2500
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.1261
    Cell Significance Index: -1.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.1269
    Cell Significance Index: -1.2200
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1368
    Cell Significance Index: -1.2800
  • Cell Name: naive T cell (CL0000898)
    Fold Change: -0.1376
    Cell Significance Index: -1.2500
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: -0.1401
    Cell Significance Index: -1.2500
  • Cell Name: contractile cell (CL0000183)
    Fold Change: -0.1439
    Cell Significance Index: -0.2800
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.1463
    Cell Significance Index: -1.2800
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: -0.1470
    Cell Significance Index: -1.4000
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.1547
    Cell Significance Index: -1.4100
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: -0.1555
    Cell Significance Index: -1.2500
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1805
    Cell Significance Index: -1.3800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Location:** The PRY gene is located on the Y-chromosome, which is a unique characteristic of this gene. 2. **Expression Pattern:** PRY is significantly expressed in various cell types, including progenitor cells, oligodendrocyte precursor cells, microglial cells, megakaryocyte-erythroid progenitor cells, blood vessel endothelial cells, epithelial cells of the alveoli in the lungs, hematopoietic stem cells, T cells, erythrocytes, and megakaryocytes. 3. **Protein Structure:** Although the protein structure of PRY is not available, its similarity to PTPN13 suggests that it may possess phosphatase activity. **Pathways and Functions:** 1. **Cell Signaling:** PRY may be involved in cell signaling pathways that regulate cell growth, differentiation, and survival. Its expression in various cell types suggests that it plays a role in maintaining tissue homeostasis. 2. **Immune Responses:** PRY's expression in T cells and microglial cells suggests that it may be involved in immune responses, particularly in the context of inflammation and immune cell activation. 3. **Hematopoiesis:** PRY's expression in megakaryocyte-erythroid progenitor cells and hematopoietic stem cells suggests that it may be involved in the regulation of hematopoiesis, the process by which blood cells are produced. **Clinical Significance:** 1. **Cancer Association:** PRY's expression in various cancer types, including leukemia and lymphoma, suggests that it may be involved in tumorigenesis and cancer progression. 2. **Immunological Disorders:** PRY's expression in T cells and microglial cells suggests that it may be involved in immunological disorders, such as autoimmune diseases and inflammatory conditions. 3. **Regenerative Medicine:** PRY's expression in progenitor cells and stem cells suggests that it may be involved in regenerative medicine, particularly in the context of tissue repair and repair. In conclusion, PRY is a gene with a complex and multifaceted role in various cellular processes. Further research is needed to fully elucidate its functional significance and to explore its potential applications in medicine.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.