Details for: SPO11
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: progenitor cell (CL0011026)
Fold Change: 8.24
Marker Score: 53,066 - Cell Name: microglial cell (CL0000129)
Fold Change: 3.76
Marker Score: 6,848 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 3.16
Marker Score: 3,181 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 2.21
Marker Score: 1,522 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.39
Marker Score: 879 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.29
Marker Score: 1,851 - Cell Name: germ cell (CL0000586)
Fold Change: 1.26
Marker Score: 2,198 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.16
Marker Score: 7,693 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.05
Marker Score: 805 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,833 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1
Marker Score: 2,537 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,061 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,356 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.93
Marker Score: 1,507 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,744 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,291 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 714 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.78
Marker Score: 402 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.77
Marker Score: 507 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.74
Marker Score: 213 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.71
Marker Score: 182 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.67
Marker Score: 534 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.62
Marker Score: 380 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.57
Marker Score: 151 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.57
Marker Score: 237 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.5
Marker Score: 481 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.47
Marker Score: 283 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.44
Marker Score: 251 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.37
Marker Score: 377 - Cell Name: mast cell (CL0000097)
Fold Change: 0.36
Marker Score: 211 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.34
Marker Score: 694 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.28
Marker Score: 101 - Cell Name: pericyte (CL0000669)
Fold Change: 0.23
Marker Score: 137 - Cell Name: macrophage (CL0000235)
Fold Change: 0.23
Marker Score: 259 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: 0.22
Marker Score: 119 - Cell Name: oocyte (CL0000023)
Fold Change: 0.22
Marker Score: 54 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.17
Marker Score: 325 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.16
Marker Score: 168 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.15
Marker Score: 79 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.15
Marker Score: 2,313 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.12
Marker Score: 210 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.11
Marker Score: 270 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.11
Marker Score: 232 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.1
Marker Score: 121 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.09
Marker Score: 27 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.08
Marker Score: 49 - Cell Name: podocyte (CL0000653)
Fold Change: 0.06
Marker Score: 22 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.06
Marker Score: 15 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.06
Marker Score: 25 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.05
Marker Score: 65 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.05
Marker Score: 25 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.05
Marker Score: 34 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.05
Marker Score: 16 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.05
Marker Score: 17 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.04
Marker Score: 258 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.04
Marker Score: 16 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.04
Marker Score: 12 - Cell Name: T cell (CL0000084)
Fold Change: 0.04
Marker Score: 64 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.04
Marker Score: 96 - Cell Name: leukocyte (CL0000738)
Fold Change: 0.03
Marker Score: 19 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.03
Marker Score: 15 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.03
Marker Score: 23 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.03
Marker Score: 28 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.03
Marker Score: 23 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.03
Marker Score: 17 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.02
Marker Score: 22 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.02
Marker Score: 16 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.02
Marker Score: 83 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.02
Marker Score: 200 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.02
Marker Score: 24 - Cell Name: monocyte (CL0000576)
Fold Change: 0.02
Marker Score: 24 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.02
Marker Score: 8 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.02
Marker Score: 12 - Cell Name: natural killer cell (CL0000623)
Fold Change: 0.02
Marker Score: 22 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.02
Marker Score: 169 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 0.02
Marker Score: 15 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 0.01
Marker Score: 9 - Cell Name: club cell (CL0000158)
Fold Change: 0.01
Marker Score: 17 - Cell Name: B cell (CL0000236)
Fold Change: 0.01
Marker Score: 13 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.01
Marker Score: 13 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.01
Marker Score: 9 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.01
Marker Score: 16 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.01
Marker Score: 17 - Cell Name: basal cell (CL0000646)
Fold Change: 0.01
Marker Score: 15 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.01
Marker Score: 18 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.01
Marker Score: 18 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.01
Marker Score: 16 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.01
Marker Score: 24 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.01
Marker Score: 14 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.01
Marker Score: 13 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.01
Marker Score: 14 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.01
Marker Score: 18 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.01
Marker Score: 14 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.01
Marker Score: 16 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 0.01
Marker Score: 14 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 0.01
Marker Score: 16 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.01
Marker Score: 16 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.01
Marker Score: 18 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0.01
Marker Score: 16
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1400137905
Symbol: SPO11_HUMAN
Name: Meiotic recombination protein SPO11
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10622720
Title: Differential gene expression of mammalian SPO11/TOP6A homologs during meiosis.
PubMed ID: 10622720
PubMed ID: 10534401
Title: Cloning, characterization, and localization of mouse and human SPO11.
PubMed ID: 10534401
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 396
- Mass: 44537
- Checksum: 117A93D1E7BEBEC8
- Sequence:
MAFAPMGPEA SFFDVLDRHR ESLLAALRRG GREPPTGGSR LASSSEVLAS IENIIQDIIT SLARNEAPAF TIDNRSSWEN IKFEDSVGLQ MVSHCTTRKI KSDSPKSAQK FSLILKILSM IYKLVQSNTY ATKRDIYYTD SQLFGNQTVV DNIINDISCM LKVSRRSLHI LSTSKGLIAG NLRYIEEDGT KVNCTCGATA VAVPSNIQGI RNLVTDAKFV LIVEKDATFQ RLLDDNFCNK LSPCIMITGK GVPDLNTRLL VKKLWDTFHV PVFTLVDADP HGIEIMCIYK YGSMSMSFEA HHLTVPAIRW LGLLPSDLKR LNVPKDSLIP LTKRDQMKLD SILRRPYVTC QPFWRKEMEI MADSKMKAEI QALTFLSSDY LSRVYLPNKL KFGGWI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.