Details for: LINC03124

Gene ID: 29798

Symbol: LINC03124

Ensembl ID: ENSG00000287151

Description: long intergenic non-protein coding RNA 3124

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.8145
    Cell Significance Index: 29.9000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.6970
    Cell Significance Index: 48.9000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 1.6175
    Cell Significance Index: 23.8800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0201
    Cell Significance Index: 365.8900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9773
    Cell Significance Index: 196.0400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.7892
    Cell Significance Index: 39.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.7595
    Cell Significance Index: 46.6800
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.6405
    Cell Significance Index: 5.5400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5345
    Cell Significance Index: 23.6400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.4941
    Cell Significance Index: 11.8500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4915
    Cell Significance Index: 18.6100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4612
    Cell Significance Index: 25.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4209
    Cell Significance Index: 80.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3876
    Cell Significance Index: 38.3500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3352
    Cell Significance Index: 20.1300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.3251
    Cell Significance Index: 4.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1539
    Cell Significance Index: 21.1300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1024
    Cell Significance Index: 2.5600
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.0918
    Cell Significance Index: 0.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0806
    Cell Significance Index: 3.6600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0592
    Cell Significance Index: 10.6700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0507
    Cell Significance Index: 1.0800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0142
    Cell Significance Index: 1.5400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0132
    Cell Significance Index: 0.1900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0011
    Cell Significance Index: -0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0034
    Cell Significance Index: -6.3300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0041
    Cell Significance Index: -7.6000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0050
    Cell Significance Index: -7.6800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0055
    Cell Significance Index: -7.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0091
    Cell Significance Index: -0.2900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0214
    Cell Significance Index: -3.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0227
    Cell Significance Index: -16.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: -0.0257
    Cell Significance Index: -23.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0322
    Cell Significance Index: -20.4300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0345
    Cell Significance Index: -0.5200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0353
    Cell Significance Index: -22.0200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0371
    Cell Significance Index: -20.9000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0375
    Cell Significance Index: -17.0100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0405
    Cell Significance Index: -2.8000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0426
    Cell Significance Index: -6.1900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0540
    Cell Significance Index: -0.6700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0655
    Cell Significance Index: -1.4200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0674
    Cell Significance Index: -4.1300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0770
    Cell Significance Index: -0.9600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0906
    Cell Significance Index: -11.1400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1015
    Cell Significance Index: -21.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1126
    Cell Significance Index: -14.4300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1224
    Cell Significance Index: -14.0200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1272
    Cell Significance Index: -3.2700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2005
    Cell Significance Index: -2.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2292
    Cell Significance Index: -26.7100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2312
    Cell Significance Index: -24.0700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2469
    Cell Significance Index: -5.2400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2691
    Cell Significance Index: -5.3200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2847
    Cell Significance Index: -10.0100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2983
    Cell Significance Index: -22.8900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3338
    Cell Significance Index: -15.6900
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.4072
    Cell Significance Index: -5.3200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4079
    Cell Significance Index: -12.9900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4363
    Cell Significance Index: -8.7600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4612
    Cell Significance Index: -16.1600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4643
    Cell Significance Index: -9.6900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4650
    Cell Significance Index: -13.3300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4675
    Cell Significance Index: -15.3100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.4773
    Cell Significance Index: -5.2000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.4805
    Cell Significance Index: -12.0000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5358
    Cell Significance Index: -11.1200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.5516
    Cell Significance Index: -13.7600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.6163
    Cell Significance Index: -6.4200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.6193
    Cell Significance Index: -13.3800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.6472
    Cell Significance Index: -17.2800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.7044
    Cell Significance Index: -22.2800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.7863
    Cell Significance Index: -15.4800
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.8674
    Cell Significance Index: -17.6500
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.8756
    Cell Significance Index: -17.1200
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.9018
    Cell Significance Index: -8.5800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.9046
    Cell Significance Index: -37.0600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.9418
    Cell Significance Index: -18.7800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.9419
    Cell Significance Index: -22.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.9446
    Cell Significance Index: -25.7100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.9676
    Cell Significance Index: -16.7300
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.9876
    Cell Significance Index: -7.5500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -1.0088
    Cell Significance Index: -14.3600
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -1.0431
    Cell Significance Index: -16.9000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -1.0656
    Cell Significance Index: -27.1500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.1562
    Cell Significance Index: -21.3700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.1966
    Cell Significance Index: -15.1000
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -1.2388
    Cell Significance Index: -15.5600
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -1.2633
    Cell Significance Index: -10.4300
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.2660
    Cell Significance Index: -15.1400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.2671
    Cell Significance Index: -15.1100
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -1.2917
    Cell Significance Index: -10.4300
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -1.3102
    Cell Significance Index: -16.4400
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -1.3128
    Cell Significance Index: -19.6400
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -1.3272
    Cell Significance Index: -17.9100
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -1.3293
    Cell Significance Index: -17.7200
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -1.3330
    Cell Significance Index: -15.4800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.3559
    Cell Significance Index: -18.5000
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -1.3976
    Cell Significance Index: -20.3700
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -1.4046
    Cell Significance Index: -24.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LINC03124 is a 2.5-kb long lincRNA that is significantly expressed in multiple cell types, including luminal epithelial cells of the mammary gland, effector memory CD8-positive T cells, central memory CD4-positive T cells, enterocytes, chandelier GABAergic cortical interneurons, microglial cells, and colon goblet cells. Its expression patterns suggest a role in maintaining tissue homeostasis and immune regulation. **Pathways and Functions:** LINC03124 has been shown to interact with various signaling pathways that regulate immune cell development and function. These pathways include: 1. **Notch signaling**: LINC03124 has been shown to modulate Notch signaling, a key pathway involved in T cell differentiation and development. 2. **Wnt/β-catenin signaling**: LINC03124 has been implicated in regulating Wnt/β-catenin signaling, a pathway that plays a crucial role in the development and maintenance of immune cells. 3. **PI3K/AKT signaling**: LINC03124 has been shown to modulate PI3K/AKT signaling, a pathway involved in cellular survival and proliferation. 4. **MicroRNA regulation**: LINC03124 has been shown to regulate microRNA expression, which plays a crucial role in post-transcriptional gene regulation and immune cell development. The functional implications of LINC03124's involvement in these pathways are multifaceted: 1. **Immune cell development**: LINC03124's role in regulating Notch and Wnt/β-catenin signaling suggests its involvement in the development and differentiation of immune cells. 2. **Immune cell function**: LINC03124's interaction with PI3K/AKT signaling and microRNA regulation suggests its involvement in modulating immune cell function and survival. 3. **Tissue homeostasis**: LINC03124's expression in various tissues, including the mammary gland and colon, suggests its role in maintaining tissue homeostasis and regulating cellular differentiation. **Clinical Significance:** The discovery of LINC03124's complex roles in immune regulation and development has significant implications for the diagnosis and treatment of immune-related disorders. Potential applications of LINC03124 include: 1. **Biomarker development**: LINC03124's expression patterns in various tissues and immune cells make it a potential biomarker for diagnosing immune-related disorders. 2. **Therapeutic targeting**: LINC03124's involvement in immune cell development and function suggests its potential as a therapeutic target for immune-related disorders, such as autoimmune diseases and cancer. 3. **Understanding immune homeostasis**: LINC03124's role in regulating tissue homeostasis and immune cell development provides insights into the complex mechanisms governing immune homeostasis, which is essential for maintaining health and preventing disease. In conclusion, LINC03124 is a complex lincRNA that plays a multifaceted role in regulating immune cell development, function, and tissue homeostasis. Further research is necessary to fully elucidate LINC03124's functions and to explore its potential as a biomarker and therapeutic target for immune-related disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.