Details for: TBCE
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 19.7658
Cell Significance Index: -8.0300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 8.5049
Cell Significance Index: -8.1200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 3.2348
Cell Significance Index: 80.8600 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.0672
Cell Significance Index: 13.0000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 1.4951
Cell Significance Index: 22.5300 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 1.2954
Cell Significance Index: 18.8800 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.1943
Cell Significance Index: 17.3400 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.9836
Cell Significance Index: 8.3600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.8125
Cell Significance Index: 154.6200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6385
Cell Significance Index: 18.2200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5834
Cell Significance Index: 15.8800 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.4960
Cell Significance Index: 3.8600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4799
Cell Significance Index: 47.4800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3758
Cell Significance Index: 22.5600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3627
Cell Significance Index: 327.4500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3602
Cell Significance Index: 22.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.3595
Cell Significance Index: 41.8900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3098
Cell Significance Index: 33.7000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.3096
Cell Significance Index: 4.7900 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.2999
Cell Significance Index: 3.8000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2900
Cell Significance Index: 13.5200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2753
Cell Significance Index: 18.5100 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.2720
Cell Significance Index: 2.8200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2681
Cell Significance Index: 12.1500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2627
Cell Significance Index: 42.7300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2466
Cell Significance Index: 49.4700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.2291
Cell Significance Index: 3.8600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2221
Cell Significance Index: 6.4000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.2203
Cell Significance Index: 6.4900 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.2194
Cell Significance Index: 3.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1999
Cell Significance Index: 10.4200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1985
Cell Significance Index: 10.3100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1604
Cell Significance Index: 11.0900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1273
Cell Significance Index: 45.6500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0990
Cell Significance Index: 11.3500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0826
Cell Significance Index: 1.7900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0682
Cell Significance Index: 13.5300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0484
Cell Significance Index: 8.2700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.0264
Cell Significance Index: 0.3900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0247
Cell Significance Index: 38.1000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0151
Cell Significance Index: 0.5300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0123
Cell Significance Index: 23.1500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0117
Cell Significance Index: 21.5700 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.0081
Cell Significance Index: 0.1400 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.0060
Cell Significance Index: 0.0500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.0039
Cell Significance Index: 0.2400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.0007
Cell Significance Index: 0.0200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0027
Cell Significance Index: -3.7000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0061
Cell Significance Index: -3.8900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0075
Cell Significance Index: -5.5300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0088
Cell Significance Index: -4.9500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0136
Cell Significance Index: -8.5000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0137
Cell Significance Index: -6.2400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0160
Cell Significance Index: -0.3400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0263
Cell Significance Index: -3.8200 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0349
Cell Significance Index: -0.5000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0365
Cell Significance Index: -7.6900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0623
Cell Significance Index: -1.3000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0659
Cell Significance Index: -6.8600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0849
Cell Significance Index: -2.7200 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: -0.1178
Cell Significance Index: -1.1400 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.1427
Cell Significance Index: -1.8500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1433
Cell Significance Index: -5.0200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1513
Cell Significance Index: -4.8200 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1524
Cell Significance Index: -3.1000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1542
Cell Significance Index: -5.0500 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.1594
Cell Significance Index: -2.0600 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.1646
Cell Significance Index: -2.2200 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1647
Cell Significance Index: -2.7700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1685
Cell Significance Index: -3.6400 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.1728
Cell Significance Index: -2.2600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1767
Cell Significance Index: -3.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1819
Cell Significance Index: -8.5500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1854
Cell Significance Index: -2.5300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1869
Cell Significance Index: -11.4900 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1964
Cell Significance Index: -4.9000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1989
Cell Significance Index: -5.2300 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.2088
Cell Significance Index: -2.9300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2097
Cell Significance Index: -4.2100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2295
Cell Significance Index: -5.6000 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.2373
Cell Significance Index: -3.9100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2387
Cell Significance Index: -4.7200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.2479
Cell Significance Index: -10.7800 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.2641
Cell Significance Index: -4.1900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2734
Cell Significance Index: -7.3000 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.2754
Cell Significance Index: -5.4200 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: -0.2834
Cell Significance Index: -4.2400 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.2861
Cell Significance Index: -4.0000 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.2963
Cell Significance Index: -4.1100 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.3027
Cell Significance Index: -4.2000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3113
Cell Significance Index: -5.2100 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.3485
Cell Significance Index: -8.8800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.3513
Cell Significance Index: -8.7600 - Cell Name: neuron (CL0000540)
Fold Change: -0.3524
Cell Significance Index: -3.3400 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.3539
Cell Significance Index: -8.8400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3550
Cell Significance Index: -10.1800 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.3556
Cell Significance Index: -4.5600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3654
Cell Significance Index: -7.5800 - Cell Name: Mueller cell (CL0000636)
Fold Change: -0.3691
Cell Significance Index: -2.8400 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.3696
Cell Significance Index: -7.3700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 412169850
Symbol: TBCE_HUMAN
Name: Tubulin-specific chaperone E
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8706133
Title: Pathway leading to correctly folded beta-tubulin.
PubMed ID: 8706133
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11847227
Title: Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C.
PubMed ID: 11847227
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 27666374
Title: Biallelic TBCD mutations cause early-onset neurodegenerative encephalopathy.
PubMed ID: 27666374
PubMed ID: 27666369
Title: TBCE mutations cause early-onset progressive encephalopathy with distal spinal muscular atrophy.
PubMed ID: 27666369
PubMed ID: 12389028
Title: Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome.
PubMed ID: 12389028
DOI: 10.1038/ng1012
Sequence Information:
- Length: 527
- Mass: 59346
- Checksum: C919052D2D463BA1
- Sequence:
MSDTLTADVI GRRVEVNGEH ATVRFAGVVP PVAGPWLGVE WDNPERGKHD GSHEGTVYFK CRHPTGGSFI RPNKVNFGTD FLTAIKNRYV LEDGPEEDRK EQIVTIGNKP VETIGFDSIM KQQSQLSKLQ EVSLRNCAVS CAGEKGGVAE ACPNIRKVDL SKNLLSSWDE VIHIADQLRH LEVLNVSENK LKFPSGSVLT GTLSVLKVLV LNQTGITWAE VLRCVAGCPG LEELYLESNN IFISERPTDV LQTVKLLDLS SNQLIDENQL YLIAHLPRLE QLILSDTGIS SLHFPDAGIG CKTSMFPSLK YLVVNDNQIS QWSFFNELEK LPSLRALSCL RNPLTKEDKE AETARLLIIA SIGQLKTLNK CEILPEERRR AELDYRKAFG NEWKQAGGHK DPEKNRLSEE FLTAHPRYQF LCLKYGAPED WELKTQQPLM LKNQLLTLKI KYPHQLDQKV LEKQLPGSMT IQKVKGLLSR LLKVPVSDLL LSYESPKKPG REIELENDLK SLQFYSVENG DCLLVRW
Genular Protein ID: 3600004349
Symbol: A0A2R8Y6Q1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 414
- Mass: 46877
- Checksum: 2F27838C79E1CC73
- Sequence:
MYPCELCFSC SQLSKLQEVS LRNCAVSCAG EKGGVAEACP NIRKVDLSKN LLSSWDEVIH IADQLRHLEV LNVSENKLKF PSGSVLTGTL SVLKVLVLNQ TGITWAEVLR CVAGCPGLEE LYLESNNIFI SERPTDVLQT VKLLDLSSNQ LIDENQLYLI AHLPRLEQLI LSDTGISSLH FPDAGIGCKT SMFPSLKYLV VNDNQISQWS FFNELEKLPS LRALSCLRNP LTKEDKEAET ARLLIIASIG QLKTLNKCEI LPEERRRAEL DYRKAFGNEW KQAGGHKDPE KNRLSEEFLT AHPRYQFLCL KYGAPEDWEL KTQQPLMLKN QLLTLKIKYP HQLDQKVLEK QLPGSMTIQK VKGLLSRLLK VPVSDLLLSY ESPKKPGREI ELENDLKSLQ FYSVENGDCL LVRW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.