Details for: NOX1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 7.8695
Cell Significance Index: 196.7200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 2.1724
Cell Significance Index: 46.2700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2.1056
Cell Significance Index: 95.4400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.0522
Cell Significance Index: 390.5400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.5993
Cell Significance Index: 158.2100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.5583
Cell Significance Index: 23.3500 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.1820
Cell Significance Index: 28.6300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.0775
Cell Significance Index: 34.5100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9658
Cell Significance Index: 872.0800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8571
Cell Significance Index: 139.4000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5348
Cell Significance Index: 36.9900 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.5029
Cell Significance Index: 7.3300 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.4121
Cell Significance Index: 2.9000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.2622
Cell Significance Index: 5.6100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1713
Cell Significance Index: 8.9000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1648
Cell Significance Index: 2.3600 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.1610
Cell Significance Index: 1.7500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1511
Cell Significance Index: 2.5900 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.1343
Cell Significance Index: 1.7300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1151
Cell Significance Index: 1.5700 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.0875
Cell Significance Index: 0.5400 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.0300
Cell Significance Index: 0.3800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0178
Cell Significance Index: 3.5800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0148
Cell Significance Index: 0.3200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0123
Cell Significance Index: 2.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0121
Cell Significance Index: 2.0600 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.0115
Cell Significance Index: 0.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0101
Cell Significance Index: 0.2900 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 0.0076
Cell Significance Index: 0.0700 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.0070
Cell Significance Index: 0.1000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.0068
Cell Significance Index: 0.1000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0050
Cell Significance Index: 1.7900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0048
Cell Significance Index: 0.0500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0045
Cell Significance Index: 0.3000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0042
Cell Significance Index: 0.1200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0032
Cell Significance Index: 0.5900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0029
Cell Significance Index: 5.2800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0022
Cell Significance Index: 4.0700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0016
Cell Significance Index: 2.4300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0011
Cell Significance Index: 1.4400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0003
Cell Significance Index: 0.0100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0005
Cell Significance Index: -0.0200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0014
Cell Significance Index: -0.0500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0018
Cell Significance Index: -0.2600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0022
Cell Significance Index: -1.6900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0023
Cell Significance Index: -1.4700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0023
Cell Significance Index: -1.7100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0024
Cell Significance Index: -0.7000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0026
Cell Significance Index: -1.4200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0027
Cell Significance Index: -0.0600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0028
Cell Significance Index: -1.2600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0028
Cell Significance Index: -1.5700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0032
Cell Significance Index: -1.9700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0051
Cell Significance Index: -0.3100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0087
Cell Significance Index: -1.8300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0103
Cell Significance Index: -1.2700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0103
Cell Significance Index: -1.4100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0112
Cell Significance Index: -1.1700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0116
Cell Significance Index: -1.3300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0183
Cell Significance Index: -0.4900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0185
Cell Significance Index: -0.5900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0209
Cell Significance Index: -0.4200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0210
Cell Significance Index: -0.4100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0214
Cell Significance Index: -0.5500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0222
Cell Significance Index: -1.7000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0260
Cell Significance Index: -0.8500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0303
Cell Significance Index: -1.0600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0318
Cell Significance Index: -0.6600 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0322
Cell Significance Index: -0.8100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0323
Cell Significance Index: -1.8100 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0325
Cell Significance Index: -0.6900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0340
Cell Significance Index: -2.0900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0351
Cell Significance Index: -1.6500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0382
Cell Significance Index: -1.0200 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.0387
Cell Significance Index: -0.2400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0401
Cell Significance Index: -1.0000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0414
Cell Significance Index: -1.5200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0426
Cell Significance Index: -0.9200 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0435
Cell Significance Index: -0.8600 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0436
Cell Significance Index: -1.3800 - Cell Name: stem cell (CL0000034)
Fold Change: -0.0454
Cell Significance Index: -0.3300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0476
Cell Significance Index: -2.4800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0484
Cell Significance Index: -1.3800 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0506
Cell Significance Index: -1.0300 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0508
Cell Significance Index: -1.2400 - Cell Name: goblet cell (CL0000160)
Fold Change: -0.0509
Cell Significance Index: -0.4600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0513
Cell Significance Index: -1.5100 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: -0.0596
Cell Significance Index: -0.3500 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0613
Cell Significance Index: -1.2800 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.0627
Cell Significance Index: -0.7900 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0645
Cell Significance Index: -0.6800 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0649
Cell Significance Index: -1.5000 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0650
Cell Significance Index: -0.8500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0677
Cell Significance Index: -1.0000 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: -0.0677
Cell Significance Index: -0.6600 - Cell Name: neuron (CL0000540)
Fold Change: -0.0686
Cell Significance Index: -0.6500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0692
Cell Significance Index: -1.9400 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.0697
Cell Significance Index: -0.9400 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0711
Cell Significance Index: -1.2300 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0727
Cell Significance Index: -1.4300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 122685811
Symbol: NOX1_HUMAN
Name: NADPH oxidase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10485709
Title: Cell transformation by the superoxide-generating oxidase Mox1.
PubMed ID: 10485709
DOI: 10.1038/43459
PubMed ID: 10615049
Title: A mammalian H+ channel, generated through alternative splicing of the NADPH oxidase homolog NOH-1.
PubMed ID: 10615049
Title:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14617635
Title: NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain.
PubMed ID: 14617635
PubMed ID: 16329988
Title: Molecular interaction of NADPH oxidase 1 with betaPix and Nox Organizer 1.
PubMed ID: 16329988
PubMed ID: 16636067
Title: Nox1-dependent reactive oxygen generation is regulated by Rac1.
PubMed ID: 16636067
PubMed ID: 19755710
Title: Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity.
PubMed ID: 19755710
PubMed ID: 24365146
Title: N-Linked glycosylation of the superoxide-producing NADPH oxidase Nox1.
PubMed ID: 24365146
PubMed ID: 26301257
Title: Defects in NADPH oxidase genes NOX1 and DUOX2 in very early onset inflammatory bowel disease.
PubMed ID: 26301257
Sequence Information:
- Length: 564
- Mass: 64871
- Checksum: C3BE290F4E6DBC9A
- Sequence:
MGNWVVNHWF SVLFLVVWLG LNVFLFVDAF LKYEKADKYY YTRKILGSTL ACARASALCL NFNSTLILLP VCRNLLSFLR GTCSFCSRTL RKQLDHNLTF HKLVAYMICL HTAIHIIAHL FNFDCYSRSR QATDGSLASI LSSLSHDEKK GGSWLNPIQS RNTTVEYVTF TSIAGLTGVI MTIALILMVT SATEFIRRSY FEVFWYTHHL FIFYILGLGI HGIGGIVRGQ TEESMNESHP RKCAESFEMW DDRDSHCRRP KFEGHPPESW KWILAPVILY ICERILRFYR SQQKVVITKV VMHPSKVLEL QMNKRGFSME VGQYIFVNCP SISLLEWHPF TLTSAPEEDF FSIHIRAAGD WTENLIRAFE QQYSPIPRIE VDGPFGTASE DVFQYEVAVL VGAGIGVTPF ASILKSIWYK FQCADHNLKT KKIYFYWICR ETGAFSWFNN LLTSLEQEME ELGKVGFLNY RLFLTGWDSN IVGHAALNFD KATDIVTGLK QKTSFGRPMW DNEFSTIATS HPKSVVGVFL CGPRTLAKSL RKCCHRYSSL DPRKVQFYFN KENF
Genular Protein ID: 1983769164
Symbol: Q1ZYL4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 527
- Mass: 60915
- Checksum: 6995CB1F494BA52A
- Sequence:
MGNWVVNHWF SVLFLVVWLG LNVFLFVDAF LKYEKADKYY YTRKILGFCS RTLRKQLDHN LTFHKLVAYM ICLHTAIHII AHLFNFDCYS RSRQATDGSL ASILSSLSHD EKKGGSWLNP IQSRNTTVEY VTFTSIAGLT GVIMTIALIL MVTSATEFIR RSYFEVFWYT HHLFIFYILG LGIHGIGGIV RGQTEESMNE SHPRKCAESF EMWDDRDSHC RRPKFEGHPP ESWKWILAPV ILYICERILR FYRSQQKVVI TKVVMHPSKV LELQMNKRGF SMEVGQYIFV NCPSISLLEW HPFTLASAPE EDFFSIHIRA AGDWTENLIR AFEQQYSPIP RIEVDGPFGT ASEDVFQYEV AVLVGAGIGV TPFASILKSI WYKFQCADHN LKTKKIYFYW ICRETGAFSW FNNLLTSLEQ EMEELGKVGF LNYRLFLTGW DSNIVGHAAL NFDKATDIVT GLKQKTSFGR PMWDNEFSTI ATSHPKSVVG VFLCGPRTLA KSLRKCCHRY SSLDPRKVQF YFNKENF
Genular Protein ID: 4141687593
Symbol: A6NGA6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15772651
Sequence Information:
- Length: 527
- Mass: 60945
- Checksum: D4320163EE848D9C
- Sequence:
MGNWVVNHWF SVLFLVVWLG LNVFLFVDAF LKYEKADKYY YTRKILGFCS RTLRKQLDHN LTFHKLVAYM ICLHTAIHII AHLFNFDCYS RSRQATDGSL ASILSSLSHD EKKGGSWLNP IQSRNTTVEY VTFTSIAGLT GVIMTIALIL MVTSATEFIR RSYFEVFWYT HHLFIFYILG LGIHGIGGIV RGQTEESMNE SHPRKCAESF EMWDDRDSHC RRPKFEGHPP ESWKWILAPV ILYICERILR FYRSQQKVVI TKVVMHPSKV LELQMNKRGF SMEVGQYIFV NCPSISLLEW HPFTLTSAPE EDFFSIHIRA AGDWTENLIR AFEQQYSPIP RIEVDGPFGT ASEDVFQYEV AVLVGAGIGV TPFASILKSI WYKFQCADHN LKTKKIYFYW ICRETGAFSW FNNLLTSLEQ EMEELGKVGF LNYRLFLTGW DSNIVGHAAL NFDKATDIVT GLKQKTSFGR PMWDNEFSTI ATSHPKSVVG VFLCGPRTLA KSLRKCCHRY SSLDPRKVQF YFNKENF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.