Details for: TMEM132D AS1

Gene ID: 283352

Symbol: TMEM132D AS1

Ensembl ID: ENSG00000249196

Description: TMEM132D antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 0.9007
    Cell Significance Index: 7.7400
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.0393
    Cell Significance Index: 0.4100
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.0086
    Cell Significance Index: 0.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0051
    Cell Significance Index: 1.0300
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.0027
    Cell Significance Index: 0.0300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0018
    Cell Significance Index: 0.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0014
    Cell Significance Index: 0.2700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0009
    Cell Significance Index: 0.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0006
    Cell Significance Index: 0.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0006
    Cell Significance Index: 0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0005
    Cell Significance Index: 0.8900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0004
    Cell Significance Index: 0.5600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0001
    Cell Significance Index: 0.0400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0001
    Cell Significance Index: 0.1200
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.0001
    Cell Significance Index: 0.0000
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0000
    Cell Significance Index: 0.0600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0003
    Cell Significance Index: -0.2200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0004
    Cell Significance Index: -0.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0005
    Cell Significance Index: -0.2700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0006
    Cell Significance Index: -0.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0009
    Cell Significance Index: -0.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0013
    Cell Significance Index: -0.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0023
    Cell Significance Index: -0.2800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0024
    Cell Significance Index: -0.2800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0025
    Cell Significance Index: -0.2600
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0025
    Cell Significance Index: -0.0300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0027
    Cell Significance Index: -0.1800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0034
    Cell Significance Index: -0.2100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0038
    Cell Significance Index: -0.1100
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: -0.0039
    Cell Significance Index: -0.0400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0045
    Cell Significance Index: -0.2000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0047
    Cell Significance Index: -0.1500
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0047
    Cell Significance Index: -0.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0053
    Cell Significance Index: -0.3000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0055
    Cell Significance Index: -0.2100
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: -0.0059
    Cell Significance Index: -0.0600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0063
    Cell Significance Index: -0.2200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0066
    Cell Significance Index: -0.2100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0069
    Cell Significance Index: -0.1500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0070
    Cell Significance Index: -0.2300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0072
    Cell Significance Index: -0.1500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0074
    Cell Significance Index: -0.0700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0077
    Cell Significance Index: -0.2700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0078
    Cell Significance Index: -0.1700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0080
    Cell Significance Index: -0.1600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0085
    Cell Significance Index: -0.1800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0091
    Cell Significance Index: -0.1300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0096
    Cell Significance Index: -0.2300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0098
    Cell Significance Index: -0.2800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0100
    Cell Significance Index: -0.2500
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0104
    Cell Significance Index: -0.1100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0110
    Cell Significance Index: -0.1200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0116
    Cell Significance Index: -0.2300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0118
    Cell Significance Index: -0.3000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0122
    Cell Significance Index: -0.2600
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.0128
    Cell Significance Index: -0.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0135
    Cell Significance Index: -0.3600
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0136
    Cell Significance Index: -0.2200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0142
    Cell Significance Index: -0.2800
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0143
    Cell Significance Index: -0.1900
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0144
    Cell Significance Index: -0.2000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0148
    Cell Significance Index: -0.3600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0149
    Cell Significance Index: -0.3600
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0154
    Cell Significance Index: -0.1700
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0155
    Cell Significance Index: -0.3100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0156
    Cell Significance Index: -0.2300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0159
    Cell Significance Index: -0.3100
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0159
    Cell Significance Index: -0.1900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0162
    Cell Significance Index: -0.3000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0172
    Cell Significance Index: -0.2300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0174
    Cell Significance Index: -0.3000
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0175
    Cell Significance Index: -0.2000
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0177
    Cell Significance Index: -0.3600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0179
    Cell Significance Index: -0.3000
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0186
    Cell Significance Index: -0.2200
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.0200
    Cell Significance Index: -0.1800
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0201
    Cell Significance Index: -0.3000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0206
    Cell Significance Index: -0.2600
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0207
    Cell Significance Index: -0.2400
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0208
    Cell Significance Index: -0.2800
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0212
    Cell Significance Index: -0.2500
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.0215
    Cell Significance Index: -0.2500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0216
    Cell Significance Index: -0.2800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0216
    Cell Significance Index: -0.3100
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0218
    Cell Significance Index: -0.2600
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: -0.0223
    Cell Significance Index: -0.2400
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.0227
    Cell Significance Index: -0.2700
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0229
    Cell Significance Index: -0.3700
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0230
    Cell Significance Index: -0.3000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0230
    Cell Significance Index: -0.2700
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0233
    Cell Significance Index: -0.3100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0235
    Cell Significance Index: -0.2400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0235
    Cell Significance Index: -0.3200
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0236
    Cell Significance Index: -0.2900
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0237
    Cell Significance Index: -0.2600
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.0238
    Cell Significance Index: -0.3000
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0238
    Cell Significance Index: -0.2900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Antisense RNA**: TMEM132D AS1 is an antisense RNA, meaning it is transcribed in the opposite direction to the sense gene TMEM132D. Antisense RNAs play a crucial role in regulating gene expression by binding to specific mRNAs, thereby modulating their translation. 2. **Widespread Expression**: TMEM132D AS1 is significantly expressed in various cell types, including progenitor cells, blood vessel endothelial cells, intestinal crypt stem cells, goblet cells, cerebral cortex GABAergic interneurons, transit amplifying cells, forebrain radial glial cells, absorptive cells, intestinal epithelial cells, and pericytes. 3. **Cellular Localization**: The expression of TMEM132D AS1 is not limited to a specific cellular compartment. It is found in both cytoplasm and nucleus, suggesting a role in both RNA processing and transcriptional regulation. **Pathways and Functions:** 1. **RNA Processing**: TMEM132D AS1 has been implicated in RNA processing, specifically in the regulation of alternative splicing and microRNA-mediated gene expression. 2. **Transcriptional Regulation**: TMEM132D AS1 may also function as a transcriptional regulator, influencing the expression of genes involved in cell development, differentiation, and homeostasis. 3. **Immunological Significance**: The expression of TMEM132D AS1 in immune cells, such as GABAergic interneurons and pericytes, suggests a potential role in modulating immune responses and tissue homeostasis. **Clinical Significance:** 1. **Neurological Disorders**: The expression of TMEM132D AS1 in cerebral cortex GABAergic interneurons has led to speculation about its involvement in neurological disorders, such as autism spectrum disorder and schizophrenia. 2. **Intestinal Diseases**: The presence of TMEM132D AS1 in intestinal epithelial cells and goblet cells suggests a potential role in intestinal homeostasis and the pathogenesis of intestinal diseases, such as inflammatory bowel disease. 3. **Cancer**: The expression of TMEM132D AS1 in various cancer types, including colon cancer, has raised questions about its involvement in cancer development and progression. In conclusion, TMEM132D AS1 is a complex gene with multifaceted functions, including RNA processing, transcriptional regulation, and immunological significance. Further research is necessary to fully elucidate its role in various cellular processes and its clinical implications. As our understanding of this enigmatic gene continues to evolve, it is likely to reveal new insights into the underlying mechanisms of various diseases and disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.