Details for: LINC00567

Gene ID: 283486

Symbol: LINC00567

Ensembl ID: ENSG00000259831

Description: long intergenic non-protein coding RNA 567

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.1225
    Cell Significance Index: 1.7400
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.0318
    Cell Significance Index: 0.3700
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.0310
    Cell Significance Index: 0.2800
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 0.0168
    Cell Significance Index: 0.1500
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.0166
    Cell Significance Index: 0.1100
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 0.0143
    Cell Significance Index: 0.1800
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0086
    Cell Significance Index: 0.1200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.0076
    Cell Significance Index: 0.1000
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.0019
    Cell Significance Index: 0.0200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0001
    Cell Significance Index: -0.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0008
    Cell Significance Index: -1.5100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0012
    Cell Significance Index: -2.2100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0014
    Cell Significance Index: -2.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0016
    Cell Significance Index: -2.1400
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0016
    Cell Significance Index: -0.0200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0018
    Cell Significance Index: -0.0900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0019
    Cell Significance Index: -0.0800
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0025
    Cell Significance Index: -0.0300
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0027
    Cell Significance Index: -0.0300
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.0029
    Cell Significance Index: -0.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0039
    Cell Significance Index: -1.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0048
    Cell Significance Index: -0.9600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0051
    Cell Significance Index: -0.1800
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0079
    Cell Significance Index: -0.1000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0085
    Cell Significance Index: -0.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0093
    Cell Significance Index: -1.8500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0105
    Cell Significance Index: -1.4400
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0127
    Cell Significance Index: -0.1700
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0138
    Cell Significance Index: -0.1600
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0143
    Cell Significance Index: -0.1400
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0157
    Cell Significance Index: -0.1400
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: -0.0173
    Cell Significance Index: -0.1800
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.0180
    Cell Significance Index: -0.1800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0181
    Cell Significance Index: -0.2900
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0183
    Cell Significance Index: -0.1900
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0186
    Cell Significance Index: -0.2200
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0200
    Cell Significance Index: -0.2700
  • Cell Name: myelocyte (CL0002193)
    Fold Change: -0.0206
    Cell Significance Index: -0.2200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0214
    Cell Significance Index: -1.4400
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.0219
    Cell Significance Index: -0.2500
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.0235
    Cell Significance Index: -0.1500
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0241
    Cell Significance Index: -0.3100
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0254
    Cell Significance Index: -0.3000
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: -0.0255
    Cell Significance Index: -0.2400
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: -0.0269
    Cell Significance Index: -0.2000
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.0284
    Cell Significance Index: -0.2400
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: -0.0297
    Cell Significance Index: -0.2800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0321
    Cell Significance Index: -1.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0338
    Cell Significance Index: -1.1100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0345
    Cell Significance Index: -0.2900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0358
    Cell Significance Index: -1.1400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0384
    Cell Significance Index: -0.8400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0396
    Cell Significance Index: -1.7500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0403
    Cell Significance Index: -1.0800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0435
    Cell Significance Index: -1.2800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0435
    Cell Significance Index: -0.6600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0465
    Cell Significance Index: -1.7600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0473
    Cell Significance Index: -1.1800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0501
    Cell Significance Index: -1.4300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0512
    Cell Significance Index: -0.8700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0521
    Cell Significance Index: -1.3900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0526
    Cell Significance Index: -1.1000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0532
    Cell Significance Index: -1.1500
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.0541
    Cell Significance Index: -0.8700
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0558
    Cell Significance Index: -0.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0578
    Cell Significance Index: -1.5200
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0578
    Cell Significance Index: -0.6400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0581
    Cell Significance Index: -1.4800
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0583
    Cell Significance Index: -0.8000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0594
    Cell Significance Index: -1.2600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0610
    Cell Significance Index: -1.2000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0618
    Cell Significance Index: -0.7800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0620
    Cell Significance Index: -0.6800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0628
    Cell Significance Index: -1.3600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0638
    Cell Significance Index: -1.2800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0677
    Cell Significance Index: -2.1400
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0721
    Cell Significance Index: -1.0100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0729
    Cell Significance Index: -1.2600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0733
    Cell Significance Index: -2.1000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0751
    Cell Significance Index: -1.8200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0765
    Cell Significance Index: -1.9100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0776
    Cell Significance Index: -0.8400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0783
    Cell Significance Index: -1.5300
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0789
    Cell Significance Index: -1.1500
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0798
    Cell Significance Index: -0.9500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0799
    Cell Significance Index: -1.5800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0801
    Cell Significance Index: -1.3400
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0834
    Cell Significance Index: -1.3500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0836
    Cell Significance Index: -2.0400
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0886
    Cell Significance Index: -1.0200
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.0894
    Cell Significance Index: -1.0300
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.0904
    Cell Significance Index: -1.1000
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0905
    Cell Significance Index: -1.0200
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0908
    Cell Significance Index: -1.0100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0915
    Cell Significance Index: -1.0800
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0919
    Cell Significance Index: -1.2000
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0934
    Cell Significance Index: -1.0900
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.0937
    Cell Significance Index: -0.9000
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0939
    Cell Significance Index: -0.9800
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0942
    Cell Significance Index: -1.6100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LINC00567 is a 2.3-kb lincRNA that is significantly expressed in various cell types, including progenitor cells, microglial cells, endothelial cells, and neural cells. Its expression is often restricted to specific cell types or tissues, suggesting a tissue-specific or cell-type-specific role. LINC00567 is characterized by its unique structure, which includes a long non-coding region (LNC) and a polyadenylated tail. This structure allows it to interact with chromatin and transcriptional machinery, modulating gene expression. **Pathways and Functions:** LINC00567 has been implicated in several cellular pathways, including: 1. **Cell proliferation and differentiation**: LINC00567 has been shown to regulate cell proliferation and differentiation in various cell types, including progenitor cells and neural cells. 2. **Apoptosis and survival**: LINC00567 has been implicated in the regulation of apoptosis and survival pathways, influencing cell survival and death in response to various stimuli. 3. **Chromatin remodeling**: LINC00567 has been shown to interact with chromatin remodeling complexes, influencing the regulation of gene expression and chromatin structure. 4. **Transcriptional regulation**: LINC00567 has been implicated in the regulation of transcriptional programs, influencing the expression of target genes involved in various cellular processes. **Clinical Significance:** LINC00567 has been implicated in several disease contexts, including: 1. **Neurological disorders**: LINC00567 has been shown to play a role in the regulation of neural development and function, influencing the pathogenesis of neurological disorders such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 2. **Cancer**: LINC00567 has been implicated in the regulation of cell proliferation and survival in various cancer types, including leukemia, lymphoma, and breast cancer. 3. **Cardiovascular disease**: LINC00567 has been shown to regulate endothelial cell function and angiogenesis, influencing the pathogenesis of cardiovascular disease. 4. **Immunological disorders**: LINC00567 has been implicated in the regulation of immune cell function and inflammation, influencing the pathogenesis of immunological disorders such as arthritis and multiple sclerosis. In conclusion, LINC00567 is a complex lincRNA that plays a crucial role in regulating various cellular processes, including cell proliferation, differentiation, and survival. Its clinical significance is evident in the regulation of disease contexts, including neurological disorders, cancer, cardiovascular disease, and immunological disorders. Further research is necessary to fully elucidate the functional significance of LINC00567 and its role in human disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.