Details for: LINC01343

Gene ID: 339442

Symbol: LINC01343

Ensembl ID: ENSG00000237290

Description: long intergenic non-protein coding RNA 1343

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.7798
    Cell Significance Index: 18.8900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.7071
    Cell Significance Index: 7.3200
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.4321
    Cell Significance Index: 5.6700
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.2882
    Cell Significance Index: 4.2000
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.1361
    Cell Significance Index: 1.7100
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.0712
    Cell Significance Index: 0.9300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0547
    Cell Significance Index: 0.9200
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.0253
    Cell Significance Index: 0.3200
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: 0.0218
    Cell Significance Index: 0.2900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0127
    Cell Significance Index: 0.1900
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.0049
    Cell Significance Index: 0.0800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0000
    Cell Significance Index: -0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0001
    Cell Significance Index: -0.2700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0002
    Cell Significance Index: -0.0100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0005
    Cell Significance Index: -0.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0013
    Cell Significance Index: -0.0500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0021
    Cell Significance Index: -0.1300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0022
    Cell Significance Index: -0.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0037
    Cell Significance Index: -0.0800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0039
    Cell Significance Index: -0.2200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0044
    Cell Significance Index: -0.1600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0049
    Cell Significance Index: -0.3300
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0058
    Cell Significance Index: -0.0400
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0066
    Cell Significance Index: -0.0800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0070
    Cell Significance Index: -0.2000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0082
    Cell Significance Index: -0.2700
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0085
    Cell Significance Index: -0.0900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0092
    Cell Significance Index: -0.1000
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0101
    Cell Significance Index: -0.1200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0113
    Cell Significance Index: -0.2400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0121
    Cell Significance Index: -0.2900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0127
    Cell Significance Index: -0.1200
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0127
    Cell Significance Index: -0.1400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0128
    Cell Significance Index: -0.2500
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.0131
    Cell Significance Index: -0.1300
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0133
    Cell Significance Index: -0.1800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0137
    Cell Significance Index: -0.3000
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0138
    Cell Significance Index: -0.1300
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0143
    Cell Significance Index: -0.1900
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0146
    Cell Significance Index: -0.1800
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0151
    Cell Significance Index: -0.2000
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0151
    Cell Significance Index: -0.2100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0152
    Cell Significance Index: -0.3000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0153
    Cell Significance Index: -0.3200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0154
    Cell Significance Index: -0.3100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0159
    Cell Significance Index: -0.2800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0160
    Cell Significance Index: -0.2000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0161
    Cell Significance Index: -0.2000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0161
    Cell Significance Index: -0.2200
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0166
    Cell Significance Index: -0.2100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0169
    Cell Significance Index: -0.2500
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0171
    Cell Significance Index: -0.2100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0174
    Cell Significance Index: -0.2200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0178
    Cell Significance Index: -0.3500
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0178
    Cell Significance Index: -0.2400
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0180
    Cell Significance Index: -0.2400
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0181
    Cell Significance Index: -0.2300
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: -0.0188
    Cell Significance Index: -0.1700
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0189
    Cell Significance Index: -0.2000
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0193
    Cell Significance Index: -0.1400
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: -0.0196
    Cell Significance Index: -0.2200
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: -0.0198
    Cell Significance Index: -0.2200
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0203
    Cell Significance Index: -0.2400
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0208
    Cell Significance Index: -0.2600
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0214
    Cell Significance Index: -0.2800
  • Cell Name: myelocyte (CL0002193)
    Fold Change: -0.0220
    Cell Significance Index: -0.2400
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0224
    Cell Significance Index: -0.2800
  • Cell Name: invaginating midget bipolar cell (CL4033034)
    Fold Change: -0.0227
    Cell Significance Index: -0.2800
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0233
    Cell Significance Index: -0.2500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0235
    Cell Significance Index: -0.2800
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0236
    Cell Significance Index: -0.2700
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0238
    Cell Significance Index: -0.3100
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0247
    Cell Significance Index: -0.3300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.0250
    Cell Significance Index: -0.3500
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: -0.0258
    Cell Significance Index: -0.2700
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0259
    Cell Significance Index: -0.3000
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0260
    Cell Significance Index: -0.2900
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0261
    Cell Significance Index: -0.2800
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0264
    Cell Significance Index: -0.2400
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0265
    Cell Significance Index: -0.3200
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0269
    Cell Significance Index: -0.3100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0270
    Cell Significance Index: -0.3500
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0271
    Cell Significance Index: -0.3200
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0272
    Cell Significance Index: -0.3200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0281
    Cell Significance Index: -0.3900
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0286
    Cell Significance Index: -0.2500
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0289
    Cell Significance Index: -0.3200
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0291
    Cell Significance Index: -0.2800
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0295
    Cell Significance Index: -0.3300
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.0298
    Cell Significance Index: -0.3000
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.0298
    Cell Significance Index: -0.3000
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0303
    Cell Significance Index: -0.2500
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.0306
    Cell Significance Index: -0.3700
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0315
    Cell Significance Index: -0.3200
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.0316
    Cell Significance Index: -0.3600
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: -0.0321
    Cell Significance Index: -0.3200
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: -0.0337
    Cell Significance Index: -0.2400
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -0.0346
    Cell Significance Index: -0.3500
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: -0.0351
    Cell Significance Index: -0.2900
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0351
    Cell Significance Index: -0.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression profile:** LINC01343 is significantly expressed in a wide range of cell types, including Bergmann glial cells, pericytes, neuronal receptor cells, T cells, neutrophils, smooth muscle myoblasts, plasma cells, lymphoid lineage-restricted progenitor cells, astrocytes, and B cells. 2. **Non-coding nature:** As a lincRNA, LINC01343 does not encode a protein but instead regulates gene expression through various mechanisms. 3. **Regulatory mechanisms:** LINC01343 modulates gene expression by interacting with chromatin, influencing the activity of transcription factors, and regulating the expression of target genes. **Pathways and Functions:** LINC01343 has been implicated in several signaling pathways, including: 1. **Immune cell signaling:** LINC01343 modulates the activity of immune cells, such as T cells and neutrophils, by regulating the expression of cytokines, chemokines, and other immune-related genes. 2. **Inflammation:** LINC01343 has been shown to regulate the expression of pro-inflammatory and anti-inflammatory genes, influencing the development of inflammation and tissue damage. 3. **Cell differentiation:** LINC01343 plays a role in regulating cell differentiation, particularly in the development of immune cells and tissue-specific cell types. 4. **Stem cell maintenance:** LINC01343 has been implicated in maintaining stem cell populations, including lymphoid lineage-restricted progenitor cells. **Clinical Significance:** LINC01343 has been linked to several immune-related disorders, including: 1. **Autoimmune diseases:** LINC01343 has been implicated in the pathogenesis of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, by regulating immune cell function and inflammation. 2. **Cancer:** LINC01343 has been shown to regulate the expression of genes involved in cancer progression and metastasis, making it a potential therapeutic target in cancer treatment. 3. **Inflammatory bowel disease:** LINC01343 has been implicated in the pathogenesis of inflammatory bowel disease, such as Crohn's disease and ulcerative colitis, by regulating inflammation and immune cell function. 4. **Neurological disorders:** LINC01343 has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease, by regulating inflammation and immune cell function in the central nervous system. In conclusion, LINC01343 is a critical regulator of immune responses, inflammation, and tissue homeostasis. Further research is needed to fully elucidate the mechanisms by which LINC01343 modulates gene expression and its clinical significance in immune-related disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.