Details for: ITGA7
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 3.91
Marker Score: 1429 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 3
Marker Score: 10668 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.68
Marker Score: 1450 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.53
Marker Score: 2411 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.5
Marker Score: 55872 - Cell Name: fat cell (CL0000136)
Fold Change: 1.9
Marker Score: 1063 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 1.9
Marker Score: 1351 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.89
Marker Score: 40386 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.81
Marker Score: 1188 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.8
Marker Score: 3956 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.55
Marker Score: 1652 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.52
Marker Score: 4348 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.36
Marker Score: 428 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.27
Marker Score: 19810 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.15
Marker Score: 2868 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 1.14
Marker Score: 300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.13
Marker Score: 1746 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.03
Marker Score: 1933.5 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.02
Marker Score: 884 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71813 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48038 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.98
Marker Score: 904.5 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30408 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 505 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 459 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5329 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2736 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.91
Marker Score: 1049 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 322 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.88
Marker Score: 250 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5296 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.85
Marker Score: 406 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.8
Marker Score: 6101 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.79
Marker Score: 444 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.79
Marker Score: 1599 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.79
Marker Score: 600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1257 - Cell Name: pericyte (CL0000669)
Fold Change: 0.77
Marker Score: 449 - Cell Name: brush cell (CL0002204)
Fold Change: 0.76
Marker Score: 698 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.76
Marker Score: 1440.5 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 393 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.74
Marker Score: 188 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.74
Marker Score: 233 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.73
Marker Score: 294 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.73
Marker Score: 1708 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 0.72
Marker Score: 211 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7
Marker Score: 2933.5 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.7
Marker Score: 458 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 176 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 0.65
Marker Score: 437 - Cell Name: bronchial smooth muscle cell (CL0002598)
Fold Change: 0.59
Marker Score: 167 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.58
Marker Score: 368 - Cell Name: mural cell (CL0008034)
Fold Change: 0.56
Marker Score: 64789 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.55
Marker Score: 146 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.55
Marker Score: 2132 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 439 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.54
Marker Score: 20492 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.52
Marker Score: 312 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.52
Marker Score: 2005 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.51
Marker Score: 227 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.49
Marker Score: 2591 - Cell Name: muscle precursor cell (CL0000680)
Fold Change: 0.49
Marker Score: 127 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 0.48
Marker Score: 369 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.46
Marker Score: 1907 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.45
Marker Score: 145 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.44
Marker Score: 746 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.44
Marker Score: 212 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.43
Marker Score: 181 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.4
Marker Score: 264 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.4
Marker Score: 124 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.39
Marker Score: 5869 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.38
Marker Score: 174 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.38
Marker Score: 142 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.36
Marker Score: 2190 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.36
Marker Score: 454 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.36
Marker Score: 93 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.35
Marker Score: 3022 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.35
Marker Score: 3325 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.34
Marker Score: 3479 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.33
Marker Score: 146 - Cell Name: germ cell (CL0000586)
Fold Change: 0.33
Marker Score: 568 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.31
Marker Score: 131 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.31
Marker Score: 587 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.3
Marker Score: 68 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.3
Marker Score: 210 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.3
Marker Score: 201 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.3
Marker Score: 298 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.29
Marker Score: 3917.5 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.29
Marker Score: 1215 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.28
Marker Score: 273.5 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.27
Marker Score: 105 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.27
Marker Score: 110 - Cell Name: myometrial cell (CL0002366)
Fold Change: 0.26
Marker Score: 76 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.26
Marker Score: 83 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.26
Marker Score: 351 - Cell Name: glial cell (CL0000125)
Fold Change: 0.26
Marker Score: 283 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.25
Marker Score: 430.5 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.25
Marker Score: 87 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.25
Marker Score: 125
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Other Information
Genular Protein ID: 3188033869
Symbol: ITA7_HUMAN
Name: Integrin alpha-7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9473524
Title: A novel extracellular domain variant of the human integrin alpha 7 subunit generated by alternative intron splicing.
PubMed ID: 9473524
PubMed ID: 9590299
Title: Mutations in the integrin alpha7 gene cause congenital myopathy.
PubMed ID: 9590299
DOI: 10.1038/ng0598-94
PubMed ID: 10403775
Title: Structure, genetic localization, and identification of the cardiac and skeletal muscle transcripts of the human integrin alpha7 gene (ITGA7).
PubMed ID: 10403775
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8126096
Title: Expression of alpha 7 integrin cytoplasmic domains during skeletal muscle development: alternate forms, conformational change, and homologies with serine/threonine kinases and tyrosine phosphatases.
PubMed ID: 8126096
PubMed ID: 9352853
Title: Relation between integrin alpha7Bbeta1 expression in human intestinal cells and enterocytic differentiation.
PubMed ID: 9352853
PubMed ID: 1839357
Title: Laminin-binding integrin alpha 7 beta 1: functional characterization and expression in normal and malignant melanocytes.
PubMed ID: 1839357
DOI: 10.1091/mbc.2.10.805
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 9307969
Title: The laminin-binding activity of the alpha 7 integrin receptor is defined by developmentally regulated splicing in the extracellular domain.
PubMed ID: 9307969
DOI: 10.1091/mbc.8.9.1723
PubMed ID: 10694445
Title: The role of extracellular and cytoplasmic splice domains of alpha7-integrin in cell adhesion and migration on laminins.
PubMed ID: 10694445
PubMed ID: 8626012
Title: Synaptic integrins in developing, adult, and mutant muscle: selective association of alpha1, alpha7A, and alpha7B integrins with the neuromuscular junction.
PubMed ID: 8626012
PubMed ID: 17641293
Title: Laminin-binding integrin alpha7 is required for contractile phenotype expression by human airway myocytes.
PubMed ID: 17641293
PubMed ID: 18940796
Title: Genetically determined proteolytic cleavage modulates alpha7beta1 integrin function.
PubMed ID: 18940796
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 22779914
Title: Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.
PubMed ID: 22779914
DOI: 10.1139/o2012-021
Sequence Information:
- Length: 1181
- Mass: 128948
- Checksum: 341C0C72CDB8CA57
- Sequence:
MAGARSRDPW GASGICYLFG SLLVELLFSR AVAFNLDVMG ALRKEGEPGS LFGFSVALHR QLQPRPQSWL LVGAPQALAL PGQQANRTGG LFACPLSLEE TDCYRVDIDQ GADMQKESKE NQWLGVSVRS QGPGGKIVTC AHRYEARQRV DQILETRDMI GRCFVLSQDL AIRDELDGGE WKFCEGRPQG HEQFGFCQQG TAAAFSPDSH YLLFGAPGTY NWKGTARVEL CAQGSADLAH LDDGPYEAGG EKEQDPRLIP VPANSYFGLL FVTNIDSSDP DQLVYKTLDP ADRLPGPAGD LALNSYLGFS IDSGKGLVRA EELSFVAGAP RANHKGAVVI LRKDSASRLV PEVMLSGERL TSGFGYSLAV ADLNSDGWPD LIVGAPYFFE RQEELGGAVY VYLNQGGHWA GISPLRLCGS PDSMFGISLA VLGDLNQDGF PDIAVGAPFD GDGKVFIYHG SSLGVVAKPS QVLEGEAVGI KSFGYSLSGS LDMDGNQYPD LLVGSLADTA VLFRARPILH VSHEVSIAPR SIDLEQPNCA GGHSVCVDLR VCFSYIAVPS SYSPTVALDY VLDADTDRRL RGQVPRVTFL SRNLEEPKHQ ASGTVWLKHQ HDRVCGDAMF QLQENVKDKL RAIVVTLSYS LQTPRLRRQA PGQGLPPVAP ILNAHQPSTQ RAEIHFLKQG CGEDKICQSN LQLVRARFCT RVSDTEFQPL PMDVDGTTAL FALSGQPVIG LELMVTNLPS DPAQPQADGD DAHEAQLLVM LPDSLHYSGV RALDPAEKPL CLSNENASHV ECELGNPMKR GAQVTFYLIL STSGISIETT ELEVELLLAT ISEQELHPVS ARARVFIELP LSIAGMAIPQ QLFFSGVVRG ERAMQSERDV GSKVKYEVTV SNQGQSLRTL GSAFLNIMWP HEIANGKWLL YPMQVELEGG QGPGQKGLCS PRPNILHLDV DSRDRRRREL EPPEQQEPGE RQEPSMSWWP VSSAEKKKNI TLDCARGTAN CVVFSCPLYS FDRAAVLHVW GRLWNSTFLE EYSAVKSLEV IVRANITVKS SIKNLMLRDA STVIPVMVYL DPMAVVAEGV PWWVILLAVL AGLLVLALLV LLLWKMGFFK RAKHPEATVP QYHAVKIPRE DRQQFKEEKT GTILRNNWGS PRREGPDAHP ILAADGHPEL GPDGHPGPGT A
Genular Protein ID: 4125268018
Symbol: Q4LE35_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1200
- Mass: 130819
- Checksum: 540E87C8095F8EC2
- Sequence:
LAGAGAAGWR SGGRAGGLAG RTSGRRLKDQ RDFGDQRRAW GDLGLGACEI SLAFAGSSRR DRPMAGARSR DPWGASGICY LFGSLLVELL FSRAVAFNLD VMGALRKEGE PGSLFGFSVA LHRQLQPRPQ SWLLVGAPQA LALPGQQANR TGGLFACPLS LEETDCYRVD IDQGADMQKE SKENQWLGVS VRSQGPGGKI VTCAHRYEAR QRVDQILETR DMIGRCFVLS QDLAIRDELD GGEWKFCEGR PQGHEQFGFC QQGTAAAFSP DSHYLLFGAP GTYNWKGLLF VTNIDSSDPD QLVYKTLDPA DRLPGPAGDL ALNSYLGFSI DSGKGLVRAE ELSFVAGAPR ANHKGAVVIL RKDSASRLVP EVMLSGERLT SGFGYSLAVA DLNSDGWPDL IVGAPYFFER QEELGGAVYV YLNQGGHWAG ISPLRLCGSP DSMFGISLAV LGDLNQDGFP DIAVGAPFDG DGKVFIYHGS SLGVVAKPSQ VLEGEAVGIK SFGYSLSGSL DMDGNQYPDL LVGSLADTAV LFRARPILHV SHEVSIAPRS IDLEQPNCAG GHSVCVDLRV CFSYIAVPSS YSPTVALDYV LDADTDRRLR GQVPRVTFLS RNLEEPKHQA SGTVWLKHQH DRVCGDAMFQ LQENVKDKLR AIVVTLSYSL QTPRLRRQAP GQGLPPVAPI LNAHQPSTQR AEIHFLKQGC GEDKICQSNL QLVRARFCTR VSDTEFQPLP MDVDGTTALF ALSGQPVIGL ELMVTNLPSD PAQPQADGDD AHEAQLLVML PDSLHYSGVR ALDPAEKPLC LSNENASHVE CELGNPMKRG AQVTFYLILS TSGISIETTE LEVELLLATI SEQELHPVSA RARVFIELPL SIAGMAIPQQ LFFSGVVRGE RAMQSERDVG SKVKYEVTVS NQGQSLRTLG SAFLNIMWPH EIANGKWLLY PMQVELEGGQ GPGQKGLCSP RPNILHLDVD SRDRRRRELE PPEQQEPGER QEPSMSWWPV SSAEKKKNIT LDCARGTANC VVFSCPLYSF DRAAVLHVWG RLWNSTFLEE YSAVKSLEVI VRANITVKSS IKNLMLRDAS TVIPVMVYLD PMAVVAEGVP WWVILLAVLA GLLVLALLVL LLWKMGFFKR AKHPEATVPQ YHAVKIPRED RQQFKEEKTG TILRNNWGSP RREGPDAHPI LAADGHPELG PDGHPGPGTA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.