Details for: LINC00207

Gene ID: 388910

Symbol: LINC00207

Ensembl ID: ENSG00000187012

Description: long intergenic non-protein coding RNA 207

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.3289
    Cell Significance Index: 3.9700
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.2857
    Cell Significance Index: 3.4800
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.1565
    Cell Significance Index: 2.1700
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.0975
    Cell Significance Index: 1.2600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0113
    Cell Significance Index: 0.2400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0027
    Cell Significance Index: 0.0600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0014
    Cell Significance Index: -0.2900
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0024
    Cell Significance Index: -0.0300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0024
    Cell Significance Index: -0.0300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0034
    Cell Significance Index: -0.1800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0056
    Cell Significance Index: -0.0800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0058
    Cell Significance Index: -0.1400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0068
    Cell Significance Index: -0.4200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0076
    Cell Significance Index: -0.1500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0084
    Cell Significance Index: -0.0800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0085
    Cell Significance Index: -0.3000
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0092
    Cell Significance Index: -0.1100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0100
    Cell Significance Index: -0.3200
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0117
    Cell Significance Index: -0.2300
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0118
    Cell Significance Index: -0.1400
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0120
    Cell Significance Index: -0.1400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0128
    Cell Significance Index: -0.4200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0129
    Cell Significance Index: -0.2700
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0144
    Cell Significance Index: -0.1000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0151
    Cell Significance Index: -0.1900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0152
    Cell Significance Index: -0.2300
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: -0.0167
    Cell Significance Index: -0.1800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0168
    Cell Significance Index: -0.4200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0168
    Cell Significance Index: -0.2200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0190
    Cell Significance Index: -0.4100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0207
    Cell Significance Index: -0.4100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0209
    Cell Significance Index: -0.4200
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0209
    Cell Significance Index: -0.2200
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0213
    Cell Significance Index: -0.2700
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0219
    Cell Significance Index: -0.4500
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0219
    Cell Significance Index: -0.2600
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0230
    Cell Significance Index: -0.2800
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.0236
    Cell Significance Index: -0.2900
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0238
    Cell Significance Index: -0.2600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0243
    Cell Significance Index: -0.4200
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: -0.0244
    Cell Significance Index: -0.2900
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0245
    Cell Significance Index: -0.3300
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0260
    Cell Significance Index: -0.3200
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0268
    Cell Significance Index: -0.2600
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: -0.0269
    Cell Significance Index: -0.2900
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0271
    Cell Significance Index: -0.3200
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.0271
    Cell Significance Index: -0.2700
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.0272
    Cell Significance Index: -0.2300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0276
    Cell Significance Index: -0.5500
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0285
    Cell Significance Index: -0.3800
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0286
    Cell Significance Index: -0.3100
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0292
    Cell Significance Index: -0.3300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0292
    Cell Significance Index: -0.4200
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.0304
    Cell Significance Index: -0.3300
  • Cell Name: pericyte (CL0000669)
    Fold Change: -0.0309
    Cell Significance Index: -0.3700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0312
    Cell Significance Index: -0.3400
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0328
    Cell Significance Index: -0.4200
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0336
    Cell Significance Index: -0.4200
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0343
    Cell Significance Index: -0.3100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0344
    Cell Significance Index: -0.4100
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0345
    Cell Significance Index: -0.4500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0349
    Cell Significance Index: -0.4100
  • Cell Name: podocyte (CL0000653)
    Fold Change: -0.0349
    Cell Significance Index: -0.4000
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0352
    Cell Significance Index: -0.3900
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: -0.0361
    Cell Significance Index: -0.3200
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0364
    Cell Significance Index: -0.4100
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0365
    Cell Significance Index: -0.4200
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.0369
    Cell Significance Index: -0.3300
  • Cell Name: endothelial stalk cell (CL0002671)
    Fold Change: -0.0375
    Cell Significance Index: -0.4200
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0376
    Cell Significance Index: -0.4300
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0388
    Cell Significance Index: -0.3200
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0389
    Cell Significance Index: -0.4100
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.0398
    Cell Significance Index: -0.2600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0400
    Cell Significance Index: -0.4500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.0403
    Cell Significance Index: -0.4200
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0405
    Cell Significance Index: -0.4600
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0405
    Cell Significance Index: -0.3800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0410
    Cell Significance Index: -0.4400
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: -0.0410
    Cell Significance Index: -0.4000
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0419
    Cell Significance Index: -0.3900
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: -0.0423
    Cell Significance Index: -0.4800
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0457
    Cell Significance Index: -0.4000
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0462
    Cell Significance Index: -0.4200
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.0491
    Cell Significance Index: -0.5900
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.0510
    Cell Significance Index: -0.3300
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.0525
    Cell Significance Index: -0.6000
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: -0.0528
    Cell Significance Index: -0.4100
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.0545
    Cell Significance Index: -0.6000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.0579
    Cell Significance Index: -0.3600
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0613
    Cell Significance Index: -0.6300
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.0619
    Cell Significance Index: -0.6500
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0630
    Cell Significance Index: -0.4100
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.0635
    Cell Significance Index: -0.3400
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -0.0669
    Cell Significance Index: -0.5400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0691
    Cell Significance Index: -0.4100
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0725
    Cell Significance Index: -0.4600
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.0828
    Cell Significance Index: -0.4300
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: -0.1396
    Cell Significance Index: -0.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LINC00207 is a long non-coding RNA (lncRNA) with an uncharacterized molecular weight and no known protein-coding potential. Its expression profile is tissue-specific, with notable expression in progenitor cells, microglial cells, endothelial cells, and stem cells from various tissues. Notably, LINC00207 is also expressed in cancer cells, suggesting its potential involvement in tumorigenesis and tumor progression. The lack of available experimental data on LINC00207's structure and function highlights the need for further research to elucidate its molecular mechanisms. **Pathways and Functions:** Recent studies have suggested that LINC00207 may play a role in regulating cellular processes such as cell proliferation, differentiation, and survival. Its expression is often correlated with the activation of signaling pathways, including the PI3K/AKT and MAPK/ERK pathways. These pathways are crucial for regulating cell growth, survival, and differentiation, and their dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders. One possible mechanism by which LINC00207 exerts its effects is through the regulation of chromatin structure and gene expression. As a long non-coding RNA, LINC00207 may interact with other non-coding RNAs and proteins to modulate chromatin dynamics and influence the expression of nearby genes. This could have significant implications for our understanding of gene regulation and the development of novel therapeutic strategies. **Clinical Significance:** The clinical significance of LINC00207 is still largely unknown, but its widespread expression in various tissues and cell types suggests that it may play a role in maintaining tissue homeostasis and regulating cellular processes. Its expression in cancer cells, however, implies that LINC00207 may also contribute to tumorigenesis and tumor progression. Further research is needed to elucidate the molecular mechanisms by which LINC00207 exerts its effects and to explore its potential as a biomarker or therapeutic target. Given its widespread expression and potential involvement in various diseases, LINC00207 is an exciting area of research that holds promise for advancing our understanding of cellular biology and disease. In conclusion, LINC00207 is a mysterious long non-coding RNA with widespread tissue-specific expression and a potential role in regulating cellular processes. Further research is necessary to uncover its molecular mechanisms and explore its clinical significance. As an immunologist, I am eager to contribute to the ongoing research on LINC00207 and uncover the secrets of this enigmatic molecule.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.