Details for: CEACAM6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 56.6938
Cell Significance Index: -14.3800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 21.5045
Cell Significance Index: -14.4300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.0664
Cell Significance Index: -18.9300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 3.7520
Cell Significance Index: 56.2200 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 3.5481
Cell Significance Index: 36.6000 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 1.0101
Cell Significance Index: 8.3500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8390
Cell Significance Index: 83.0000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7992
Cell Significance Index: 86.9300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6601
Cell Significance Index: 14.3000 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: 0.6095
Cell Significance Index: 4.0700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4958
Cell Significance Index: 34.2900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2063
Cell Significance Index: 9.3500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1787
Cell Significance Index: 8.3300 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.1657
Cell Significance Index: 1.1000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1517
Cell Significance Index: 4.2400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1394
Cell Significance Index: 4.9000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1219
Cell Significance Index: 110.0500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1036
Cell Significance Index: 2.9900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0878
Cell Significance Index: 66.4300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0817
Cell Significance Index: 15.5400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0650
Cell Significance Index: 35.5200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0586
Cell Significance Index: 36.6100 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.0150
Cell Significance Index: 0.6500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0141
Cell Significance Index: 1.6200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0128
Cell Significance Index: 0.3200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0087
Cell Significance Index: 0.2200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0064
Cell Significance Index: 0.7900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0060
Cell Significance Index: 1.0900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0029
Cell Significance Index: -0.4900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0056
Cell Significance Index: -4.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0077
Cell Significance Index: -14.5600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0079
Cell Significance Index: -1.6700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0081
Cell Significance Index: -4.5500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0169
Cell Significance Index: -0.2300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0184
Cell Significance Index: -33.9000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0223
Cell Significance Index: -34.3300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0238
Cell Significance Index: -1.2000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0254
Cell Significance Index: -34.5500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0270
Cell Significance Index: -17.1400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0283
Cell Significance Index: -1.1600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0324
Cell Significance Index: -0.6900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0359
Cell Significance Index: -4.1800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0385
Cell Significance Index: -13.8000 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0405
Cell Significance Index: -0.5300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0485
Cell Significance Index: -5.5400 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: -0.0501
Cell Significance Index: -0.5300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0507
Cell Significance Index: -23.0000 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0625
Cell Significance Index: -0.4200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0629
Cell Significance Index: -12.4800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0687
Cell Significance Index: -0.7800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0810
Cell Significance Index: -16.2600 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0977
Cell Significance Index: -1.6100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1102
Cell Significance Index: -15.1400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1171
Cell Significance Index: -17.0200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1417
Cell Significance Index: -4.5400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1547
Cell Significance Index: -3.2100 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.1643
Cell Significance Index: -2.3900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1789
Cell Significance Index: -23.1100 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.1924
Cell Significance Index: -2.0300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2100
Cell Significance Index: -14.1200 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.2279
Cell Significance Index: -5.5200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2360
Cell Significance Index: -6.9500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2719
Cell Significance Index: -9.9800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2766
Cell Significance Index: -16.9600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2919
Cell Significance Index: -18.8300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2935
Cell Significance Index: -21.8700 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.2991
Cell Significance Index: -7.4700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.3357
Cell Significance Index: -3.4800 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.3395
Cell Significance Index: -5.7100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3464
Cell Significance Index: -21.2900 - Cell Name: malignant cell (CL0001064)
Fold Change: -0.3474
Cell Significance Index: -1.8600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3756
Cell Significance Index: -19.5100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3957
Cell Significance Index: -22.2100 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.4046
Cell Significance Index: -2.5100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4168
Cell Significance Index: -19.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4307
Cell Significance Index: -11.5200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4661
Cell Significance Index: -16.3300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4673
Cell Significance Index: -20.6700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4951
Cell Significance Index: -14.1300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5003
Cell Significance Index: -16.3800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.5126
Cell Significance Index: -16.3300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.5324
Cell Significance Index: -14.0000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.5451
Cell Significance Index: -20.6400 - Cell Name: pulmonary alveolar type 2 cell (CL0002063)
Fold Change: -0.5580
Cell Significance Index: -4.6200 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: -0.5917
Cell Significance Index: -6.5800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.5927
Cell Significance Index: -14.7800 - Cell Name: goblet cell (CL0000160)
Fold Change: -0.5932
Cell Significance Index: -5.3700 - Cell Name: pulmonary alveolar type 1 cell (CL0002062)
Fold Change: -0.6158
Cell Significance Index: -6.7600 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.6383
Cell Significance Index: -12.4800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.6599
Cell Significance Index: -16.4600 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: -0.6676
Cell Significance Index: -6.2800 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.6906
Cell Significance Index: -9.4700 - Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
Fold Change: -0.7053
Cell Significance Index: -4.9500 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.7240
Cell Significance Index: -15.1100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.7449
Cell Significance Index: -11.2300 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.7543
Cell Significance Index: -11.6700 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.7552
Cell Significance Index: -15.0600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.7732
Cell Significance Index: -16.4100 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.7784
Cell Significance Index: -15.3200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.7868
Cell Significance Index: -17.0000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4164654688
Symbol: CEAM6_HUMAN
Name: Carcinoembryonic antigen-related cell adhesion molecule 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3220478
Title: Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.
PubMed ID: 3220478
PubMed ID: 3337731
Title: Primary structure of nonspecific crossreacting antigen (NCA), a member of carcinoembryonic antigen (CEA) gene family, deduced from cDNA sequence.
PubMed ID: 3337731
PubMed ID: 2830274
Title: Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen.
PubMed ID: 2830274
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 2803308
Title: Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion.
PubMed ID: 2803308
PubMed ID: 2317824
Title: Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.
PubMed ID: 2317824
PubMed ID: 2022629
Title: A specific heterotypic cell adhesion activity between members of carcinoembryonic antigen family, W272 and NCA, is mediated by N-domains.
PubMed ID: 2022629
PubMed ID: 1378450
Title: CD66 nonspecific cross-reacting antigens are involved in neutrophil adherence to cytokine-activated endothelial cells.
PubMed ID: 1378450
PubMed ID: 8776764
Title: Preparation and characterization of two human carcinoembryonic antigen family proteins of neutrophils, CD66b and c, in silkworm larvae.
PubMed ID: 8776764
PubMed ID: 10436421
Title: Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.
PubMed ID: 10436421
DOI: 10.1159/000030075
PubMed ID: 10910050
Title: Human carcinoembryonic antigen functions as a general inhibitor of anoikis.
PubMed ID: 10910050
PubMed ID: 11590190
Title: Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8.
PubMed ID: 11590190
PubMed ID: 14724575
Title: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells.
PubMed ID: 14724575
PubMed ID: 16204051
Title: Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).
PubMed ID: 16204051
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 26483485
Title: Diverse oligomeric states of CEACAM IgV domains.
PubMed ID: 26483485
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
Sequence Information:
- Length: 344
- Mass: 37237
- Checksum: 4322C5D6E25849F5
- Sequence:
MGPPSAPPCR LHVPWKEVLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLAHNLPQ NRIGYSWYKG ERVDGNSLIV GYVIGTQQAT PGPAYSGRET IYPNASLLIQ NVTQNDTGFY TLQVIKSDLV NEEATGQFHV YPELPKPSIS SNNSNPVEDK DAVAFTCEPE VQNTTYLWWV NGQSLPVSPR LQLSNGNMTL TLLSVKRNDA GSYECEIQNP ASANRSDPVT LNVLYGPDVP TISPSKANYR PGENLNLSCH AASNPPAQYS WFINGTFQQS TQELFIPNIT VNNSGSYMCQ AHNSATGLNR TTVTMITVSG SAPVLSAVAT VGITIGVLAR VALI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.