Details for: LINC02722

Gene ID: 105376619

Symbol: LINC02722

Ensembl ID: ENSG00000254508

Description: long intergenic non-protein coding RNA 2722

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 3.1427
    Cell Significance Index: 61.4500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.0779
    Cell Significance Index: 26.1100
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.3852
    Cell Significance Index: 5.6200
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.3235
    Cell Significance Index: 4.2500
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.2584
    Cell Significance Index: 3.2700
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.1920
    Cell Significance Index: 3.1100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.1377
    Cell Significance Index: 3.4400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.0649
    Cell Significance Index: 0.5000
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.0520
    Cell Significance Index: 0.6300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0347
    Cell Significance Index: 0.5200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0335
    Cell Significance Index: 1.5200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0187
    Cell Significance Index: 0.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0152
    Cell Significance Index: 0.7900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0127
    Cell Significance Index: 0.3800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0066
    Cell Significance Index: 0.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0053
    Cell Significance Index: 0.6800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0049
    Cell Significance Index: 0.1400
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.0048
    Cell Significance Index: 0.0500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0038
    Cell Significance Index: 0.0600
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.0034
    Cell Significance Index: 0.0300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0029
    Cell Significance Index: 0.0600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0017
    Cell Significance Index: 0.0600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0011
    Cell Significance Index: 0.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0010
    Cell Significance Index: 0.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0004
    Cell Significance Index: 0.0200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0002
    Cell Significance Index: 0.0500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0001
    Cell Significance Index: 0.0200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0000
    Cell Significance Index: -0.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0001
    Cell Significance Index: -0.0400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0002
    Cell Significance Index: -0.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0002
    Cell Significance Index: -0.0600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0002
    Cell Significance Index: -0.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0004
    Cell Significance Index: -0.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0004
    Cell Significance Index: -0.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0005
    Cell Significance Index: -0.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0005
    Cell Significance Index: -0.2900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0011
    Cell Significance Index: -0.0200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0013
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0017
    Cell Significance Index: -0.3600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0019
    Cell Significance Index: -0.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0021
    Cell Significance Index: -0.2900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0023
    Cell Significance Index: -0.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0044
    Cell Significance Index: -0.3500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0044
    Cell Significance Index: -0.0600
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0046
    Cell Significance Index: -0.0600
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0046
    Cell Significance Index: -0.0500
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0055
    Cell Significance Index: -0.0400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0057
    Cell Significance Index: -0.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0062
    Cell Significance Index: -0.2900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0063
    Cell Significance Index: -0.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0064
    Cell Significance Index: -0.3600
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.0071
    Cell Significance Index: -0.0400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0074
    Cell Significance Index: -0.2400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0076
    Cell Significance Index: -0.2500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0077
    Cell Significance Index: -0.3400
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.0077
    Cell Significance Index: -0.0800
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0080
    Cell Significance Index: -0.1000
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.0083
    Cell Significance Index: -0.0800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0087
    Cell Significance Index: -0.3200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0090
    Cell Significance Index: -0.3400
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0105
    Cell Significance Index: -0.2200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0105
    Cell Significance Index: -0.2200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0106
    Cell Significance Index: -0.0900
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0106
    Cell Significance Index: -0.1200
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0116
    Cell Significance Index: -0.1500
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0117
    Cell Significance Index: -0.1300
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0122
    Cell Significance Index: -0.2400
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0123
    Cell Significance Index: -0.1400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0130
    Cell Significance Index: -0.3700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0132
    Cell Significance Index: -0.3300
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.0132
    Cell Significance Index: -0.1000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0133
    Cell Significance Index: -0.3800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0135
    Cell Significance Index: -0.3600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0137
    Cell Significance Index: -0.1300
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0145
    Cell Significance Index: -0.1800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0146
    Cell Significance Index: -0.3100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0148
    Cell Significance Index: -0.3600
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0151
    Cell Significance Index: -0.1700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0154
    Cell Significance Index: -0.3700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0157
    Cell Significance Index: -0.3400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0159
    Cell Significance Index: -0.3200
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.0159
    Cell Significance Index: -0.1800
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0163
    Cell Significance Index: -0.2100
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0165
    Cell Significance Index: -0.2200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0167
    Cell Significance Index: -0.2800
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0168
    Cell Significance Index: -0.2000
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0169
    Cell Significance Index: -0.1300
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.0171
    Cell Significance Index: -0.2100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0172
    Cell Significance Index: -0.3400
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0173
    Cell Significance Index: -0.2300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0176
    Cell Significance Index: -0.2600
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: -0.0177
    Cell Significance Index: -0.1900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0179
    Cell Significance Index: -0.1500
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0180
    Cell Significance Index: -0.1900
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0181
    Cell Significance Index: -0.2600
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0182
    Cell Significance Index: -0.2300
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0184
    Cell Significance Index: -0.2300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0184
    Cell Significance Index: -0.2000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0185
    Cell Significance Index: -0.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **LincRNA classification**: LINC02722 belongs to the lincRNA family, which is a class of long non-coding RNAs (lncRNAs) that do not encode proteins but regulate gene expression through various mechanisms. 2. **Expression profile**: LINC02722 is significantly expressed in a wide range of cell types, including progenitor cells, oligodendrocyte precursor cells, epithelial cells, and immune cells such as microglial cells and endothelial cells. 3. **Ensembl ID**: The Ensembl ID for LINC02722 is ENSG00000255169, indicating its presence in the Ensembl database, a comprehensive resource for gene annotation and expression data. **Pathways and Functions:** 1. **Regulation of gene expression**: LINC02722 is thought to regulate gene expression by modulating chromatin structure, DNA methylation, and transcription factor activity. Its expression is often associated with the regulation of cell proliferation, differentiation, and survival. 2. **Involvement in cellular processes**: LINC02722 has been implicated in various cellular processes, including cell migration, angiogenesis, and immune responses. Its expression is often upregulated in response to tissue injury or inflammation. 3. **Interactions with other RNAs**: LINC02722 has been shown to interact with other RNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), to regulate gene expression and cellular processes. **Clinical Significance:** 1. **Immunological implications**: LINC02722's expression in immune cells, such as microglial cells and endothelial cells, suggests its potential role in regulating immune responses and inflammation. 2. **Neurological disorders**: The expression of LINC02722 in oligodendrocyte precursor cells and cerebral cortex endothelial cells has led to speculation about its involvement in neurological disorders, such as multiple sclerosis and Alzheimer's disease. 3. **Cancer research**: LINC02722's expression in various cancer types has led to its investigation as a potential biomarker and therapeutic target for cancer treatment. In conclusion, LINC02722 is a complex lincRNA with widespread tissue expression and potential immunological implications. Further research is needed to fully elucidate its role in regulating gene expression, cellular processes, and disease pathology.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.